ATE432365T1 - Verfahren, kits und reagenzien zur nukleinsäuresequenzierung - Google Patents

Verfahren, kits und reagenzien zur nukleinsäuresequenzierung

Info

Publication number
ATE432365T1
ATE432365T1 AT04713125T AT04713125T ATE432365T1 AT E432365 T1 ATE432365 T1 AT E432365T1 AT 04713125 T AT04713125 T AT 04713125T AT 04713125 T AT04713125 T AT 04713125T AT E432365 T1 ATE432365 T1 AT E432365T1
Authority
AT
Austria
Prior art keywords
nucleic acid
methods
kits
reagents
acid sequencing
Prior art date
Application number
AT04713125T
Other languages
English (en)
Inventor
Mark J Hoser
Original Assignee
Geneform Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0303964A external-priority patent/GB0303964D0/en
Priority claimed from GB0305525A external-priority patent/GB0305525D0/en
Priority claimed from GB0306119A external-priority patent/GB0306119D0/en
Priority claimed from GB0307515A external-priority patent/GB0307515D0/en
Priority claimed from GB0310294A external-priority patent/GB0310294D0/en
Priority claimed from GB0313689A external-priority patent/GB0313689D0/en
Priority claimed from GB0320157A external-priority patent/GB0320157D0/en
Priority claimed from GB0322245A external-priority patent/GB0322245D0/en
Priority claimed from GB0325657A external-priority patent/GB0325657D0/en
Priority claimed from GB0329053A external-priority patent/GB0329053D0/en
Application filed by Geneform Technologies Ltd filed Critical Geneform Technologies Ltd
Publication of ATE432365T1 publication Critical patent/ATE432365T1/de
Application granted granted Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nanotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT04713125T 2003-02-21 2004-02-20 Verfahren, kits und reagenzien zur nukleinsäuresequenzierung ATE432365T1 (de)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
GB0303964A GB0303964D0 (en) 2003-02-21 2003-02-21 FRET based sequencing technology
GB0305525A GB0305525D0 (en) 2003-03-11 2003-03-11 Inhibitor based sequencing technology
GB0306119A GB0306119D0 (en) 2003-03-18 2003-03-18 Non-incorporable label determined sequencing
GB0307515A GB0307515D0 (en) 2003-04-01 2003-04-01 Non-incorporable label determined sequencing process
GB0310294A GB0310294D0 (en) 2003-05-03 2003-05-03 Non-incorporable label determined sequencing-2
GB0313689A GB0313689D0 (en) 2003-06-13 2003-06-13 Sequencing method-j
GB0320157A GB0320157D0 (en) 2003-08-28 2003-08-28 Sequencing method-M
GB0322245A GB0322245D0 (en) 2003-09-23 2003-09-23 Nucleic acid sequencing method
GB0325657A GB0325657D0 (en) 2003-11-04 2003-11-04 Nucleic acid sequencing method
GB0329053A GB0329053D0 (en) 2003-12-16 2003-12-16 Dye conjugate based sequencing
PCT/GB2004/000709 WO2004074503A2 (en) 2003-02-21 2004-02-20 Nucleic acid sequencing methods, kits and reagents

Publications (1)

Publication Number Publication Date
ATE432365T1 true ATE432365T1 (de) 2009-06-15

Family

ID=32913446

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04713125T ATE432365T1 (de) 2003-02-21 2004-02-20 Verfahren, kits und reagenzien zur nukleinsäuresequenzierung

Country Status (5)

Country Link
US (1) US8399196B2 (de)
EP (1) EP1594987B1 (de)
AT (1) ATE432365T1 (de)
DE (1) DE602004021235D1 (de)
WO (1) WO2004074503A2 (de)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6780591B2 (en) 1998-05-01 2004-08-24 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US7875440B2 (en) 1998-05-01 2011-01-25 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US6818395B1 (en) 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
US7501245B2 (en) 1999-06-28 2009-03-10 Helicos Biosciences Corp. Methods and apparatuses for analyzing polynucleotide sequences
US6982146B1 (en) 1999-08-30 2006-01-03 The United States Of America As Represented By The Department Of Health And Human Services High speed parallel molecular nucleic acid sequencing
JP2004523243A (ja) 2001-03-12 2004-08-05 カリフォルニア インスティチュート オブ テクノロジー 非同期性塩基伸長によってポリヌクレオチド配列を分析するための方法および装置
GB0324456D0 (en) * 2003-10-20 2003-11-19 Isis Innovation Parallel DNA sequencing methods
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
ATE463584T1 (de) 2004-02-19 2010-04-15 Helicos Biosciences Corp Verfahren zur analyse von polynukleotidsequenzen
US7476734B2 (en) 2005-12-06 2009-01-13 Helicos Biosciences Corporation Nucleotide analogs
EP1766090B1 (de) 2004-05-25 2011-04-27 Helicos Biosciences Corporation Verfahren zur nukleinsäureimmobilisierung
US7220549B2 (en) 2004-12-30 2007-05-22 Helicos Biosciences Corporation Stabilizing a nucleic acid for nucleic acid sequencing
US7482120B2 (en) * 2005-01-28 2009-01-27 Helicos Biosciences Corporation Methods and compositions for improving fidelity in a nucleic acid synthesis reaction
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids
JP2009519041A (ja) * 2005-12-12 2009-05-14 アメリカ合衆国 核酸配列決定のためのプローブおよび使用方法
US8703734B2 (en) 2005-12-12 2014-04-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Nanoprobes for detection or modification of molecules
US20080145844A1 (en) * 2006-01-25 2008-06-19 Evrogen Joint Stock Company Methods of cDNA preparation
US20070202521A1 (en) * 2006-02-14 2007-08-30 Applera Corporation Single Molecule DNA Sequencing Using Fret Based Dynamic Labeling
US7397546B2 (en) 2006-03-08 2008-07-08 Helicos Biosciences Corporation Systems and methods for reducing detected intensity non-uniformity in a laser beam
CA2622649C (en) 2007-03-09 2018-04-24 Riken Nucleic acid amplification method using primer exhibiting exciton effect
ES2385268T3 (es) * 2007-03-09 2012-07-20 Riken Compuesto que tiene una estructura derivada de mononucleósido o mononucleótido, ácido nucleico, sustancia marcadora y método y kit para la detección de ácido nucleico
CA2715385A1 (en) * 2008-02-12 2009-08-20 Pacific Biosciences Of California, Inc. Compositions and methods for use in analytical reactions
US8354233B2 (en) 2008-04-01 2013-01-15 University Of Washington Sequence data by reduction of noise due to carry-over primer
WO2010002939A2 (en) * 2008-06-30 2010-01-07 Life Technologies Corporation Methods for real time single molecule sequencing
US20100227327A1 (en) * 2008-08-08 2010-09-09 Xiaoliang Sunney Xie Methods and compositions for continuous single-molecule nucleic acid sequencing by synthesis with fluorogenic nucleotides
US20100036110A1 (en) * 2008-08-08 2010-02-11 Xiaoliang Sunney Xie Methods and compositions for continuous single-molecule nucleic acid sequencing by synthesis with fluorogenic nucleotides
GB0901593D0 (en) 2009-01-30 2009-03-11 Touchlight Genetics Ltd Production of closed linear DNA
US8501405B2 (en) 2009-04-27 2013-08-06 Pacific Biosciences Of California, Inc. Real-time sequencing methods and systems
WO2010141391A2 (en) 2009-06-05 2010-12-09 Life Technologies Corporation Mutant dna polymerases
GB201013153D0 (en) 2010-08-04 2010-09-22 Touchlight Genetics Ltd Primer for production of closed linear DNA
WO2013080941A1 (ja) * 2011-12-01 2013-06-06 三菱レイヨン株式会社 核酸増幅用基材及び核酸増幅方法
GB201301178D0 (en) * 2013-01-23 2013-03-06 Dynamic Biosensors Gmbh Method for sequencing a template nucleic acid immobilized on a substrate
AU2014218911B2 (en) * 2013-02-20 2018-07-12 Eve Biomedical, Inc. Methods and compositions for nanostructure-based nucleic acid sequencing
US9146248B2 (en) 2013-03-14 2015-09-29 Intelligent Bio-Systems, Inc. Apparatus and methods for purging flow cells in nucleic acid sequencing instruments
WO2014142981A1 (en) * 2013-03-15 2014-09-18 Illumina, Inc. Enzyme-linked nucleotides
US9591268B2 (en) 2013-03-15 2017-03-07 Qiagen Waltham, Inc. Flow cell alignment methods and systems
US9546398B2 (en) * 2013-11-14 2017-01-17 Agilent Technologies, Inc. Polymerase idling method for single molecule DNA sequencing
US9909167B2 (en) 2014-06-23 2018-03-06 The Board Of Trustees Of The Leland Stanford Junior University On-slide staining by primer extension
GB201415789D0 (en) 2014-09-05 2014-10-22 Touchlight Genetics Ltd Synthesis of DNA
US10077470B2 (en) 2015-07-21 2018-09-18 Omniome, Inc. Nucleic acid sequencing methods and systems
WO2017177017A1 (en) 2016-04-07 2017-10-12 Omniome, Inc. Methods of quantifying target nucleic acids and identifying sequence variants
WO2017190018A1 (en) 2016-04-29 2017-11-02 Omniome, Inc. Sequencing method employing ternary complex destabilization to identify cognate nucleotides
EP3490616B1 (de) 2016-07-27 2022-09-28 The Board of Trustees of the Leland Stanford Junior University Hochmultiplexierte fluoreszente bildgebung
US10443098B2 (en) 2016-08-15 2019-10-15 Omniome, Inc. Method and system for sequencing nucleic acids
US10428378B2 (en) 2016-08-15 2019-10-01 Omniome, Inc. Sequencing method for rapid identification and processing of cognate nucleotide pairs
AU2017386515B2 (en) 2016-12-30 2021-08-19 Pacific Biosciences Of California, Inc. Method and system employing distinguishable polymerases for detecting ternary complexes and identifying cognate nucleotides
FI4112741T3 (fi) * 2017-01-04 2025-05-15 Mgi Tech Co Ltd Vaiheittainen sekvensointi ei-leimatuilla, reversiibeleillä terminaattoreilla tai luonnollisilla nukleotideilla
CA3049722C (en) 2017-01-10 2023-01-24 Omniome, Inc. Polymerases engineered to reduce nucleotide-independent dna binding
US9932631B1 (en) 2017-09-11 2018-04-03 Omniome, Inc. Genotyping by polymerase binding
AU2018210944B2 (en) * 2017-01-20 2021-07-22 Pacific Biosciences Of California, Inc. Process for cognate nucleotide detection in a nucleic acid sequencing workflow
CA3050241C (en) 2017-01-20 2022-11-29 Omniome, Inc. Allele-specific capture of nucleic acids
US11492666B2 (en) 2017-02-15 2022-11-08 Pacific Biosciences Of California, Inc. Distinguishing sequences by detecting polymerase dissociation
WO2018187013A1 (en) 2017-04-04 2018-10-11 Omniome, Inc. Fluidic apparatus and methods useful for chemical and biological reactions
US9951385B1 (en) 2017-04-25 2018-04-24 Omniome, Inc. Methods and apparatus that increase sequencing-by-binding efficiency
US10161003B2 (en) 2017-04-25 2018-12-25 Omniome, Inc. Methods and apparatus that increase sequencing-by-binding efficiency
US20200109446A1 (en) * 2017-06-14 2020-04-09 Board Of Regents, The University Of Texas System Chip hybridized association-mapping platform and methods of use
WO2019079593A1 (en) 2017-10-19 2019-04-25 Omniome, Inc. BACKGROUND NOISE REDUCTION AND STABILIZATION OF SIMULTANEOUS COMPLEXES IN LINKED ASSAY WORKFLOWS
AU2019217824A1 (en) * 2018-02-06 2020-07-30 Omniome, Inc. Compositions and techniques for nucleic acid primer extension
CA3097583A1 (en) * 2018-04-19 2019-10-24 Omniome, Inc. Improving accuracy of base calls in nucleic acid sequencing methods
JP7554117B2 (ja) 2018-04-26 2024-09-19 パシフィック・バイオサイエンシズ・オブ・カリフォルニア・インク. 核酸-ヌクレオチド-ポリメラーゼ複合体を安定化するための方法及び組成物
US11180794B2 (en) 2018-05-31 2021-11-23 Omniome, Inc. Methods and compositions for capping nucleic acids
JP2021525078A (ja) 2018-05-31 2021-09-24 オムニオム インコーポレイテッドOmniome, Inc. 核酸配列決定におけるシグナル対ノイズの増加
WO2019241305A1 (en) 2018-06-12 2019-12-19 Element Biosciences, Inc. Improved reverse transcriptase for nucleic acid sequencing
AU2019312152A1 (en) 2018-07-24 2021-02-18 Pacific Biosciences Of California, Inc. Serial formation of ternary complex species
US11242512B2 (en) 2018-09-17 2022-02-08 Omniome, Inc. Engineered polymerases for improved sequencing
US10876148B2 (en) 2018-11-14 2020-12-29 Element Biosciences, Inc. De novo surface preparation and uses thereof
US10704094B1 (en) 2018-11-14 2020-07-07 Element Biosciences, Inc. Multipart reagents having increased avidity for polymerase binding
US10768173B1 (en) 2019-09-06 2020-09-08 Element Biosciences, Inc. Multivalent binding composition for nucleic acid analysis
GB2613480B (en) 2018-11-15 2023-11-22 Element Biosciences Inc Methods for generating circular nucleic acid molecules
DE202019005610U1 (de) 2018-12-07 2021-06-10 Element Biosciences, Inc. Durchflusszellenvorrichtung und ihre Verwendung
US12467085B2 (en) 2019-03-07 2025-11-11 The Trustees Of Columbia University In The City Of New York High accuracy nanopore-based single molecule sequencing by synthesis with tagged nucleotides
US12313627B2 (en) 2019-05-01 2025-05-27 Element Biosciences, Inc. Multivalent binding composition for nucleic acid analysis
WO2020242901A1 (en) 2019-05-24 2020-12-03 Element Biosciences, Inc. Polymerase-nucleotide conjugates for sequencing by trapping
US12252582B2 (en) 2019-08-29 2025-03-18 University Of Delaware Biofunctional thiophene monomers and polymers thereof for electronic biomedical devices
US11287422B2 (en) 2019-09-23 2022-03-29 Element Biosciences, Inc. Multivalent binding composition for nucleic acid analysis
US20210139867A1 (en) 2019-11-08 2021-05-13 Omniome, Inc. Engineered polymerases for improved sequencing by binding
US11408032B2 (en) 2020-01-17 2022-08-09 Element Biosciences, Inc. Tube lens design for improved depth-of-field
US11198121B1 (en) * 2020-06-10 2021-12-14 Element Biosciences, Inc. Flow cell systems and devices
WO2023280156A1 (zh) * 2021-07-08 2023-01-12 深圳华大生命科学研究院 修饰的核苷或核苷酸
CN119061125A (zh) 2021-07-21 2024-12-03 元素生物科学公司 用于核酸测序的方法
WO2023129887A1 (en) * 2021-12-29 2023-07-06 Co-Diagnostics, Inc. Methods and systems for analyzing nucleic acids using increased ifret with multiple acceptor fluorophores
CN116926178B (zh) * 2022-04-02 2025-10-24 深圳市真迈生物科技有限公司 荧光检测试剂及其制备方法及应用
CA3264896A1 (en) 2022-08-15 2024-02-22 Element Biosciences, Inc. SPATIAL RESOLUTION SURFACE CAPTURE OF NUCLEIC ACIDS
EP4627115A1 (de) 2022-11-29 2025-10-08 Element Biosciences, Inc. Durchflusszellenvorrichtungen und optische systeme zur nukleinsäuresequenzierung

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6358931B1 (en) * 1990-01-11 2002-03-19 Isis Pharmaceuticals, Inc. Compositions and methods for modulating RNA
DE4140463A1 (de) * 1991-12-09 1993-06-17 Boehringer Mannheim Gmbh 2'-desoxy-isoguanosin, dessen isostere analoge sowie anwendung derselben
EP1015469B2 (de) 1997-09-12 2015-11-18 Exiqon A/S Bi- und tri-zyklische - nukleosid, nukleotid und oligonukleotid-analoga
ATE508200T1 (de) * 1999-02-23 2011-05-15 Caliper Life Sciences Inc Sequenzierung durch inkorporation
AU777049B2 (en) 1999-03-18 2004-09-30 Qiagen Gmbh Xylo-LNA analogues
US7056661B2 (en) * 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
AU2002358464B2 (en) 2001-12-18 2006-04-27 Human Genetic Signatures Pty Ltd Pseudonucleotide comprising an intercalator
US7166478B2 (en) * 2002-03-12 2007-01-23 Enzo Life Sciences, Inc., C/O Enzo Biochem, Inc. Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses
SE0202867D0 (sv) * 2002-09-27 2002-09-27 Pyrosequencing Ab New sequencing method

Also Published As

Publication number Publication date
WO2004074503A2 (en) 2004-09-02
DE602004021235D1 (de) 2009-07-09
WO2004074503A3 (en) 2005-03-24
EP1594987A2 (de) 2005-11-16
US8399196B2 (en) 2013-03-19
EP1594987B1 (de) 2009-05-27
US20070148645A1 (en) 2007-06-28

Similar Documents

Publication Publication Date Title
DE602004021235D1 (de) Verfahren, kits und reagenzien zur nukleinsäuresequenzierung
ATE550441T1 (de) Verfahren, zusammensetzungen und kits zur isothermischen amplifikation von nukleinsäuren
WO2008051530A3 (en) Polymerase enzymes and reagents for enhanced nucleic acid sequencing
WO2004092418A3 (en) Global amplification using a randomly primed composite primer
DE60220025D1 (de) Methoden und zusammensetzungen zur vervielfältigung von rna sequenzen
EP1845160A4 (de) Nukleotidsequenz-amplifikationsverfahren
ATE364718T1 (de) Verfahren zur vervielfältigung von nukleinsäure
DE60039772D1 (de) Verfahren zur amplifikation von signal-flankierend
WO2008033442A3 (en) Methods and compositions for performing low background multiplex nucleic acid amplification reactions
ATE551349T1 (de) Methode unter verwendung von reversibel blockierten markierungsoligonukleotiden
DK1513952T3 (da) Sammensætninger og fremgangsmåder til frembringelse af nukleinsyre af sputum
ATE480644T1 (de) Verfahren zur quantifizierung kleiner rna- moleküle
DE60034396D1 (de) Reaktionsgemisch und Verfahren für RT-PCR mittels einer homopolymeren Nukleinsäure
ATE500337T1 (de) Verfahren zur durchführung homologer rekombinationen in pflanzen
ATE348881T1 (de) Thermostabiles taq polymerase fragment
EP4090766B1 (de) Verfahren zur gezielten sequenzierung
DE60326327D1 (de) Verfahren und zusammensetzungen zur identifikation und charakterisierung von hepatitis c
ATE497022T1 (de) Verfahren zur amplifikation von nukleinsäure
ATE455866T1 (de) Verfahren zur unspezifischen amplifizierung nukleinsäuren mit niedriger komplexität
DE602004030036D1 (de) Multiplexanalyse von Nukleinsäuren zur Bestimmung von Genotypen des humanen Papillomavirus
WO2007076143A3 (en) Species-specific primer sets and identification of species-specific dna sequences using genome fragment enrichment
DE602004019059D1 (de) Methode zur linearen nicht-selektiven amplifikation von nukleinsäuren
CY1109285T1 (el) Ανακτηση toy dna
DE60324819D1 (de) Verfahren zur amplifikation von nukleinsäure, kit zur amplifikation von nukleinsäure, verfahren zum nachweis von einzelnukleotid-polymorphismus und reagentienkit zum nachweis von einzelnukleotid-polymorphismus
DE60331132D1 (de) Verfahren zur Quantifizierung von Nukleinsäuren

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties