ATE432942T1 - Löslicher heterodimerer cytokinrezeptor - Google Patents

Löslicher heterodimerer cytokinrezeptor

Info

Publication number
ATE432942T1
ATE432942T1 AT02713823T AT02713823T ATE432942T1 AT E432942 T1 ATE432942 T1 AT E432942T1 AT 02713823 T AT02713823 T AT 02713823T AT 02713823 T AT02713823 T AT 02713823T AT E432942 T1 ATE432942 T1 AT E432942T1
Authority
AT
Austria
Prior art keywords
cytokine receptor
heterodimeric cytokine
soluble heterodimeric
immunoglobulin
subunit
Prior art date
Application number
AT02713823T
Other languages
English (en)
Inventor
Yasmin Chandrasekher
Julia Novak
Donald Foster
Wenfeng Xu
Stephen Jaspers
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Application granted granted Critical
Publication of ATE432942T1 publication Critical patent/ATE432942T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT02713823T 2001-03-09 2002-03-07 Löslicher heterodimerer cytokinrezeptor ATE432942T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27456001P 2001-03-09 2001-03-09
US29986501P 2001-06-21 2001-06-21
PCT/US2002/007214 WO2002072607A2 (en) 2001-03-09 2002-03-07 Soluble heterodimeric cytokine receptor

Publications (1)

Publication Number Publication Date
ATE432942T1 true ATE432942T1 (de) 2009-06-15

Family

ID=26956904

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02713823T ATE432942T1 (de) 2001-03-09 2002-03-07 Löslicher heterodimerer cytokinrezeptor

Country Status (11)

Country Link
EP (1) EP1399472B1 (de)
JP (1) JP4009535B2 (de)
AT (1) ATE432942T1 (de)
AU (1) AU2002245652A1 (de)
CA (1) CA2440596C (de)
DE (1) DE60232511D1 (de)
DK (1) DK1399472T3 (de)
EA (1) EA005496B1 (de)
ES (1) ES2327821T3 (de)
IL (2) IL157726A0 (de)
WO (1) WO2002072607A2 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2393369A1 (en) 1999-12-03 2001-06-07 Zymogenetics, Inc. Human cytokine receptor
US7122632B2 (en) 1999-12-23 2006-10-17 Zymogenetics, Inc. Soluble Interleukin-20 receptor
US6610286B2 (en) 1999-12-23 2003-08-26 Zymogenetics, Inc. Method for treating inflammation using soluble receptors to interleukin-20
US20030170823A1 (en) 1999-12-23 2003-09-11 Presnell Scott R. Novel cytokine ZCYTO18
US20030023033A1 (en) * 2001-07-26 2003-01-30 Laure Dumoutier Novel class II cytokine receptors and uses thereof
EP2177616B1 (de) 2000-08-08 2012-02-29 ZymoGenetics, Inc. Lösliche Zcyctor 11 Cytokinrezeptoren
EP1803733B1 (de) 2000-09-15 2010-03-10 ZymoGenetics, Inc. Polypeptide enthaltend extrazellulären Domäne von IL-20RA und/oderr IL-20RB
CA2439961A1 (en) 2001-03-27 2002-10-03 Zymogenetics, Inc. Human cytokine receptor
AU2012216499B2 (en) * 2001-10-19 2015-05-28 Genentech, Inc. Compositions and methods for the diagnosis and treatment of inflammatory bowel disorders
DE60224822T2 (de) 2001-10-19 2009-01-22 Zymogenetics, Inc., Seattle Dimerisierter wachstumsfaktor sowie materialien und verfahren zu seiner herstellung
IL161978A0 (en) 2001-12-17 2005-11-20 Zymogenetics Inc Method for treating cervical cancer
AU2003210996A1 (en) 2002-02-11 2003-09-04 Zymogenetics, Inc. Materials and methods for preparing dimeric growth factors
EP1546358A4 (de) 2002-03-22 2006-06-07 Zymogenetics Inc Anti-il-tif-antikörper und verfahren zur verwendung bei entzündung
EP1606317B1 (de) * 2003-03-24 2010-07-28 ZymoGenetics, Inc. Anti-il-22ra antikörper und bindungspartner und verwendungsmethoden bei entzündung
JP2007501813A (ja) * 2003-08-08 2007-02-01 ノボ ノルディスク アクティーゼルスカブ 新生血管形成と関連した症状を治療および診断するためのインターロイキン−20
EP2143733A1 (de) 2003-11-21 2010-01-13 ZymoGenetics, Inc. Anti-il-20-Rezeptor-Antikörper und Bindungspartner und Verfahren zur Anwendung bei Entzündungen
EA015706B1 (ru) 2004-10-22 2011-10-31 Займоджинетикс, Инк. Моноклональное антитело или его фрагмент, связывающиеся с полипептидом il-22ra, гуманизированное антитело, полученное из указанного антитела, гибридомы, продуцирующие антитело, и применение указанного антитела
EP2192132A3 (de) 2005-02-08 2010-08-18 ZymoGenetics, Inc. Anti-il-20-, Anti-il-22- und Anti-il-22ra-Antikörper und Bindungspartner sowie Verwendungsverfahren bei Entzündungen
JP2008544746A (ja) 2005-05-12 2008-12-11 ザイモジェネティクス, インコーポレイテッド 免疫応答を調節するための組成物および方法
EP3409289B1 (de) 2010-02-26 2020-09-30 Novo Nordisk A/S Stabile, antikörperhaltige zusammensetzungen
RU2012153786A (ru) 2010-05-28 2014-07-10 Ново Нордиск А/С Стабильные многодозовые композиции, содержащие антитело и консервант
AU2015271709B2 (en) 2014-06-06 2020-11-26 Bristol-Myers Squibb Company Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof
JP6812364B2 (ja) 2015-06-03 2021-01-13 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company 癌診断用抗gitr抗体
GB201514875D0 (en) * 2015-08-20 2015-10-07 Autolus Ltd Receptor
CA3005855A1 (en) 2015-11-19 2017-05-26 Bristol-Myers Squibb Company Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof
CN110869392A (zh) 2017-05-16 2020-03-06 百时美施贵宝公司 用抗gitr激动性抗体治疗癌症

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965704A (en) * 1997-08-05 1999-10-12 Zymogenetics, Inc. Class two cytokine receptor-11
AU2222700A (en) * 1998-12-31 2000-07-31 Millennium Pharmaceuticals, Inc. Class ii cytokine receptor-like proteins and nucleic acids encoding them

Also Published As

Publication number Publication date
JP4009535B2 (ja) 2007-11-14
EP1399472A4 (de) 2004-06-30
EP1399472A2 (de) 2004-03-24
EA005496B1 (ru) 2005-02-24
IL204299A (en) 2011-06-30
JP2004536040A (ja) 2004-12-02
CA2440596C (en) 2011-05-24
WO2002072607A2 (en) 2002-09-19
DE60232511D1 (de) 2009-07-16
EP1399472B1 (de) 2009-06-03
CA2440596A1 (en) 2002-09-19
EA200300983A1 (ru) 2004-06-24
IL157726A0 (en) 2004-03-28
ES2327821T3 (es) 2009-11-04
DK1399472T3 (da) 2009-10-05
WO2002072607A3 (en) 2004-01-15
AU2002245652A1 (en) 2002-09-24

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