|
US20090137416A1
(en)
|
2001-01-16 |
2009-05-28 |
Regeneron Pharmaceuticals, Inc. |
Isolating Cells Expressing Secreted Proteins
|
|
AU2003276403B2
(en)
|
2002-11-09 |
2010-04-15 |
Adaptimmune Limited |
T cell receptor display
|
|
GB0226227D0
(en)
*
|
2002-11-09 |
2002-12-18 |
Avidex Ltd |
Receptors
|
|
GB0304068D0
(en)
*
|
2003-02-22 |
2003-03-26 |
Avidex Ltd |
Substances
|
|
US20060047433A1
(en)
*
|
2004-08-24 |
2006-03-02 |
Ishikawa Muriel Y |
System and method related to enhancing an immune system
|
|
US20060182742A1
(en)
*
|
2004-08-24 |
2006-08-17 |
Ishikawa Muriel Y |
System and method for magnifying a humoral immune response
|
|
US20060095211A1
(en)
*
|
2003-12-05 |
2006-05-04 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
System and method for modulating a cell mediated immune response
|
|
US20060047436A1
(en)
*
|
2004-08-25 |
2006-03-02 |
Ishikawa Muriel Y |
System and method for magnifying an immune response
|
|
US20060122783A1
(en)
*
|
2004-08-24 |
2006-06-08 |
Ishikawa Muriel Y |
System and method for heightening a humoral immune response
|
|
US20060047437A1
(en)
*
|
2004-08-25 |
2006-03-02 |
Ishikawa Muriel Y |
System and method for heightening an immune response
|
|
US20060047434A1
(en)
*
|
2004-08-24 |
2006-03-02 |
Ishikawa Muriel Y |
System and method related to improving an immune system
|
|
US20060122784A1
(en)
*
|
2004-12-03 |
2006-06-08 |
Ishikawa Muriel Y |
System and method for augmenting a humoral immune response
|
|
US20060047435A1
(en)
*
|
2004-08-24 |
2006-03-02 |
Ishikawa Muriel Y |
System and method related to augmenting an immune system
|
|
US20060116824A1
(en)
*
|
2004-12-01 |
2006-06-01 |
Ishikawa Muriel Y |
System and method for modulating a humoral immune response
|
|
GB0328363D0
(en)
|
2003-12-06 |
2004-01-14 |
Imp College Innovations Ltd |
Therapeutically useful molecules
|
|
JP4773434B2
(ja)
|
2004-05-19 |
2011-09-14 |
イムノコア リミテッド |
高親和性ny−esot細胞受容体
|
|
GB0411771D0
(en)
*
|
2004-05-26 |
2004-06-30 |
Avidex Ltd |
Nucleoproteins displaying native T cell receptor libraries
|
|
US20100068186A1
(en)
*
|
2004-05-26 |
2010-03-18 |
Avidex Limited |
High affinity telomerase t cell receptors
|
|
GB0411773D0
(en)
*
|
2004-05-26 |
2004-06-30 |
Avidex Ltd |
Method for the identification of polypeptides which bind to a given peptide mhc complex or cd 1-antigen complex
|
|
DK2330121T3
(en)
*
|
2004-06-02 |
2014-12-15 |
Adalta Pty Ltd |
Binding moieties based on shark IgNar domains
|
|
JP5563194B2
(ja)
*
|
2004-06-29 |
2014-07-30 |
イムノコア リミテッド |
改変t細胞レセプターを発現する細胞
|
|
US20070265818A1
(en)
*
|
2004-08-24 |
2007-11-15 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Computational methods and systems for heightening cell-mediated immune response
|
|
US20070265819A1
(en)
*
|
2004-08-24 |
2007-11-15 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Computational methods and systems for improving cell-mediated immune response
|
|
US20070198196A1
(en)
*
|
2004-08-24 |
2007-08-23 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Computational systems and methods relating to ameliorating an immune system
|
|
US20060047439A1
(en)
*
|
2004-08-24 |
2006-03-02 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
System and method for improving a humoral immune response
|
|
US20070207492A1
(en)
*
|
2004-08-24 |
2007-09-06 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Computational methods and systems to adjust a humoral immune response
|
|
US20070196362A1
(en)
*
|
2004-08-24 |
2007-08-23 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Computational methods and systems to bolster an immune response
|
|
JP2008514685A
(ja)
*
|
2004-10-01 |
2008-05-08 |
メディジーン リミテッド |
治療剤に連結した、非天然型ジスルフィド鎖間結合を含有するt細胞レセプター
|
|
JP2008520227A
(ja)
*
|
2004-11-18 |
2008-06-19 |
メディジーン リミテッド |
可溶性二官能性タンパク質
|
|
GB0425732D0
(en)
*
|
2004-11-23 |
2004-12-22 |
Avidex Ltd |
Gamma-delta t cell receptors
|
|
US20090298195A1
(en)
|
2005-01-05 |
2009-12-03 |
F-Star Biotechnologische Forschungs-Und Entwicklun Gseges M.B.H. |
Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions
|
|
WO2006103429A2
(en)
|
2005-04-01 |
2006-10-05 |
Medigene Limited |
High affinity hiv t cell receptors
|
|
GB0524477D0
(en)
*
|
2005-11-30 |
2006-01-11 |
Avidex Ltd |
Isolated T cell receptors which specifically bind to vygfvracl-hla-24
|
|
GB0511124D0
(en)
|
2005-06-01 |
2005-07-06 |
Avidex Ltd |
High affinity melan-a t cell receptors
|
|
IN2014DN06624A
(de)
|
2005-10-18 |
2015-07-10 |
Univ Colorado |
|
|
US7820174B2
(en)
|
2006-02-24 |
2010-10-26 |
The United States Of America As Represented By The Department Of Health And Human Services |
T cell receptors and related materials and methods of use
|
|
EP2027296A4
(de)
|
2006-05-31 |
2010-06-02 |
Philadelphia Children Hospital |
Zusammensetzungen und verfahren zur erkennung und modulation von t-zellen-vermittelten immunreaktionen auf virale vektoren, die für die gentherapie benutzt werden
|
|
AT503889B1
(de)
|
2006-07-05 |
2011-12-15 |
Star Biotechnologische Forschungs Und Entwicklungsges M B H F |
Multivalente immunglobuline
|
|
AT503861B1
(de)
*
|
2006-07-05 |
2008-06-15 |
F Star Biotech Forsch & Entw |
Verfahren zur manipulation von t-zell-rezeptoren
|
|
WO2008039818A2
(en)
|
2006-09-26 |
2008-04-03 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Modified t cell receptors and related materials and methods
|
|
PL3241842T3
(pl)
|
2007-06-26 |
2024-06-10 |
F-Star Therapeutics Limited |
Prezentacja środków wiążących
|
|
EP2113255A1
(de)
|
2008-05-02 |
2009-11-04 |
f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. |
Zytotoxisches Immunglobulin
|
|
US8986702B2
(en)
|
2008-05-16 |
2015-03-24 |
Taiga Biotechnologies, Inc. |
Antibodies and processes for preparing the same
|
|
EA020018B1
(ru)
*
|
2008-08-07 |
2014-08-29 |
Ипсен Фарма С.А.С. |
Процессированные аналоги глюкозозависимого инсулинотропного полипептида
|
|
DK2966084T3
(en)
|
2008-08-28 |
2018-08-06 |
Taiga Biotechnologies Inc |
MODULATORS OF MYC, PROCEDURES FOR USING SAME AND PROCEDURES FOR IDENTIFYING SUBSTANCES MODULATING MYC
|
|
US9365901B2
(en)
|
2008-11-07 |
2016-06-14 |
Adaptive Biotechnologies Corp. |
Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
|
|
US8748103B2
(en)
|
2008-11-07 |
2014-06-10 |
Sequenta, Inc. |
Monitoring health and disease status using clonotype profiles
|
|
US9528160B2
(en)
|
2008-11-07 |
2016-12-27 |
Adaptive Biotechnolgies Corp. |
Rare clonotypes and uses thereof
|
|
EP2364368B1
(de)
|
2008-11-07 |
2014-01-15 |
Sequenta, Inc. |
Verfahren zur überwachung von krankheitszuständen mittels sequenzanalyse
|
|
US9506119B2
(en)
|
2008-11-07 |
2016-11-29 |
Adaptive Biotechnologies Corp. |
Method of sequence determination using sequence tags
|
|
US8628927B2
(en)
|
2008-11-07 |
2014-01-14 |
Sequenta, Inc. |
Monitoring health and disease status using clonotype profiles
|
|
US8691510B2
(en)
|
2008-11-07 |
2014-04-08 |
Sequenta, Inc. |
Sequence analysis of complex amplicons
|
|
DK3059337T3
(da)
|
2009-01-15 |
2019-07-22 |
Adaptive Biotechnologies Corp |
Adaptive immunity profiling og metoder til frembringelse af monoklonale antibodier
|
|
WO2010088160A1
(en)
|
2009-01-28 |
2010-08-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
T cell receptors and related materials and methods of use
|
|
GB0908613D0
(en)
|
2009-05-20 |
2009-06-24 |
Immunocore Ltd |
T Cell Reseptors
|
|
RU2014144463A
(ru)
|
2009-06-25 |
2015-06-20 |
Фред Хатчинсон Кансэр Рисёч Сентер |
Способ измерения адаптивного иммунитета
|
|
GB0911566D0
(en)
*
|
2009-07-03 |
2009-08-12 |
Immunocore Ltd |
T cell receptors
|
|
CN102295702B
(zh)
*
|
2011-08-26 |
2014-01-29 |
中国科学院微生物研究所 |
一种针对t细胞受体可变区特异性单抗的制备方法
|
|
US10385475B2
(en)
|
2011-09-12 |
2019-08-20 |
Adaptive Biotechnologies Corp. |
Random array sequencing of low-complexity libraries
|
|
WO2013041865A1
(en)
|
2011-09-22 |
2013-03-28 |
Immunocore Limited |
T cell receptors
|
|
US9279159B2
(en)
|
2011-10-21 |
2016-03-08 |
Adaptive Biotechnologies Corporation |
Quantification of adaptive immune cell genomes in a complex mixture of cells
|
|
HUE053444T2
(hu)
|
2011-10-28 |
2021-06-28 |
Regeneron Pharma |
Genetikailag módosított T-sejt receptoros egerek
|
|
EP3388535B1
(de)
|
2011-12-09 |
2021-03-24 |
Adaptive Biotechnologies Corporation |
Diagnose von lymphoid-malignomen und nachweis von minimaler resterkrankung
|
|
US9499865B2
(en)
|
2011-12-13 |
2016-11-22 |
Adaptive Biotechnologies Corp. |
Detection and measurement of tissue-infiltrating lymphocytes
|
|
DK2823060T3
(en)
|
2012-03-05 |
2018-05-28 |
Adaptive Biotechnologies Corp |
Determination of associated immune receptor chains from frequency-matched subunits
|
|
EP3091089B1
(de)
|
2012-05-08 |
2019-01-23 |
Adaptive Biotechnologies Corporation |
Verfahren zum vermessen und kalibrieren eines amplifikationsbias in multiplexierten pcr-reaktionen
|
|
CN104507963B
(zh)
|
2012-05-22 |
2017-12-15 |
美国卫生和人力服务部 |
鼠抗‑ny‑eso‑1 t细胞受体
|
|
AU2013292330B2
(en)
|
2012-07-20 |
2018-07-12 |
Htyr Acquisition Llc |
Enhanced reconstitution and autoreconstitution of the hematopoietic compartment
|
|
EP2877489A4
(de)
*
|
2012-07-27 |
2016-04-13 |
Univ Illinois |
Manipulation von t-zell-rezeptoren
|
|
US20160002731A1
(en)
|
2012-10-01 |
2016-01-07 |
Adaptive Biotechnologies Corporation |
Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization
|
|
US10150996B2
(en)
|
2012-10-19 |
2018-12-11 |
Adaptive Biotechnologies Corp. |
Quantification of adaptive immune cell genomes in a complex mixture of cells
|
|
TW202423993A
(zh)
|
2012-11-14 |
2024-06-16 |
美商再生元醫藥公司 |
重組細胞表面捕捉蛋白質
|
|
GB201223172D0
(en)
|
2012-12-21 |
2013-02-06 |
Immunocore Ltd |
Method
|
|
US10272115B2
(en)
|
2013-03-11 |
2019-04-30 |
Taiga Biotechnologies, Inc. |
Production and use of red blood cells
|
|
US9708657B2
(en)
|
2013-07-01 |
2017-07-18 |
Adaptive Biotechnologies Corp. |
Method for generating clonotype profiles using sequence tags
|
|
GB201313377D0
(en)
*
|
2013-07-26 |
2013-09-11 |
Adaptimmune Ltd |
T cell receptors
|
|
EP3071594A4
(de)
|
2013-11-22 |
2017-05-03 |
The Board of Trustees of the University of Illionis |
Manipulierte hochaffine menschliche t-zell-rezeptoren
|
|
US10801070B2
(en)
|
2013-11-25 |
2020-10-13 |
The Broad Institute, Inc. |
Compositions and methods for diagnosing, evaluating and treating cancer
|
|
US11725237B2
(en)
|
2013-12-05 |
2023-08-15 |
The Broad Institute Inc. |
Polymorphic gene typing and somatic change detection using sequencing data
|
|
NZ721908A
(en)
|
2013-12-20 |
2022-12-23 |
Massachusetts Gen Hospital |
Combination therapy with neoantigen vaccine
|
|
GB201322798D0
(en)
|
2013-12-20 |
2014-02-05 |
Oxford Biomedica Ltd |
Production system
|
|
WO2015134787A2
(en)
|
2014-03-05 |
2015-09-11 |
Adaptive Biotechnologies Corporation |
Methods using randomer-containing synthetic molecules
|
|
JP2017511151A
(ja)
|
2014-03-14 |
2017-04-20 |
イムノコア リミテッド |
Tcrライブラリ
|
|
US11390921B2
(en)
|
2014-04-01 |
2022-07-19 |
Adaptive Biotechnologies Corporation |
Determining WT-1 specific T cells and WT-1 specific T cell receptors (TCRs)
|
|
US10066265B2
(en)
|
2014-04-01 |
2018-09-04 |
Adaptive Biotechnologies Corp. |
Determining antigen-specific t-cells
|
|
EP3172325B1
(de)
|
2014-07-22 |
2023-06-28 |
The University of Notre Dame du Lac |
Molekulare konstrukte und verwendungen davon
|
|
US9938026B1
(en)
|
2014-10-28 |
2018-04-10 |
Michelle Corning |
Energy beam propulsion system
|
|
US10629318B1
(en)
|
2014-10-28 |
2020-04-21 |
Michelle Corning |
Neutron beam diffraction material treatment system
|
|
US9711252B1
(en)
|
2014-10-28 |
2017-07-18 |
Michelle Corning |
High energy beam diffraction material treatment system
|
|
CA2966201A1
(en)
|
2014-10-29 |
2016-05-06 |
Adaptive Biotechnologies Corp. |
Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples
|
|
HRP20201351T1
(hr)
*
|
2014-11-05 |
2020-11-27 |
Genentech, Inc. |
Postupci proizvodnje dvolančanih proteina u bakteriji
|
|
AU2015342961B2
(en)
|
2014-11-05 |
2021-08-12 |
Genentech, Inc. |
Methods of producing two chain proteins in bacteria
|
|
CN107223133B
(zh)
|
2014-11-07 |
2021-01-29 |
广东香雪精准医疗技术有限公司 |
一种可溶的异质二聚t细胞受体及其制法和应用
|
|
US10246701B2
(en)
|
2014-11-14 |
2019-04-02 |
Adaptive Biotechnologies Corp. |
Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
|
|
EP3224384A4
(de)
|
2014-11-25 |
2018-04-18 |
Adaptive Biotechnologies Corp. |
Charakterisierung von adaptiver immunreaktion auf impfungen oder infektionen unter verwendung von immunrepertoiresequenzierung
|
|
EP4636401A2
(de)
|
2014-12-19 |
2025-10-22 |
The Broad Institute, Inc. |
Verfahren zur profilierung des t-zell-rezeptor-repertoirs
|
|
US10975442B2
(en)
|
2014-12-19 |
2021-04-13 |
Massachusetts Institute Of Technology |
Molecular biomarkers for cancer immunotherapy
|
|
CN105985427A
(zh)
*
|
2015-02-06 |
2016-10-05 |
广州市香雪制药股份有限公司 |
高亲和力ny-eso t细胞受体
|
|
US11047008B2
(en)
|
2015-02-24 |
2021-06-29 |
Adaptive Biotechnologies Corporation |
Methods for diagnosing infectious disease and determining HLA status using immune repertoire sequencing
|
|
WO2016161273A1
(en)
|
2015-04-01 |
2016-10-06 |
Adaptive Biotechnologies Corp. |
Method of identifying human compatible t cell receptors specific for an antigenic target
|
|
RU2732628C2
(ru)
|
2015-04-06 |
2020-09-21 |
Регенерон Фармасьютикалз, Инк. |
Опосредованные гуманизированными т-клетками иммунные ответы у не относящихся к человеку животных
|
|
CA2986235A1
(en)
|
2015-05-20 |
2016-11-24 |
The Broad Institute, Inc. |
Shared neoantigens
|
|
CN106279404A
(zh)
*
|
2015-05-20 |
2017-01-04 |
广州市香雪制药股份有限公司 |
一种可溶且稳定的异质二聚tcr
|
|
EP3436575A1
(de)
|
2015-06-18 |
2019-02-06 |
The Broad Institute Inc. |
Neuartige crispr-enzyme und -systeme
|
|
GB2557123B
(en)
|
2015-07-31 |
2021-11-03 |
Univ Minnesota |
Modified cells and methods of therapy
|
|
CA2997749A1
(en)
|
2015-09-09 |
2017-03-16 |
Immune Design Corp. |
Ny-eso-1 specific tcrs and methods of use thereof
|
|
GB201516272D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
|
GB201516277D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR libraries
|
|
GB201516275D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
|
GB201516270D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
|
GB201516265D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
|
GB201516269D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
|
GB201516274D0
(en)
|
2015-09-15 |
2015-10-28 |
Adaptimmune Ltd And Immunocore Ltd |
TCR Libraries
|
|
CN108291257B
(zh)
|
2015-09-24 |
2023-12-29 |
阿布维特罗有限责任公司 |
亲和-寡核苷酸缀合物及其用途
|
|
US10928392B2
(en)
|
2015-09-25 |
2021-02-23 |
Abvitro Llc |
High throughput process for T cell receptor target identification of natively-paired T cell receptor sequences
|
|
US12241053B2
(en)
|
2015-10-09 |
2025-03-04 |
The Brigham And Women's Hospital, Inc. |
Modulation of novel immune checkpoint targets
|
|
WO2017075465A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting gata3
|
|
EP3368689B1
(de)
|
2015-10-28 |
2020-06-17 |
The Broad Institute, Inc. |
Zusammensetzungen zur modulierung von immunantworten unter verwendung von immunzellgensignaturen
|
|
WO2017075451A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1
|
|
CA3005878A1
(en)
|
2015-11-19 |
2017-05-26 |
The Brigham And Women's Hospital, Inc. |
Lymphocyte antigen cd5-like (cd5l)-interleukin 12b (p40) heterodimers in immunity
|
|
GB201520597D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520541D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520568D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd |
Peptides
|
|
GB201520543D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520589D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520603D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201607534D0
(en)
|
2016-04-29 |
2016-06-15 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520564D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520558D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520557D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520536D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520592D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520550D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520575D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520544D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520579D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201604468D0
(en)
|
2016-03-16 |
2016-04-27 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520595D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520583D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520548D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520570D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520545D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520566D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520567D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520565D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520563D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201607535D0
(en)
|
2016-04-29 |
2016-06-15 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520542D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520546D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
WO2017089786A1
(en)
|
2015-11-23 |
2017-06-01 |
Immunocore Limited |
Peptides
|
|
GB201520559D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520539D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201520562D0
(en)
|
2015-11-23 |
2016-01-06 |
Immunocore Ltd & Adaptimmune Ltd |
Peptides
|
|
GB201522592D0
(en)
*
|
2015-12-22 |
2016-02-03 |
Immunocore Ltd |
T cell receptors
|
|
EA201891601A1
(ru)
|
2016-01-10 |
2019-03-29 |
Неоткс Терапьютикс Лтд. |
Способы и композиции, усиливающие эффективность опосредованной суперантигеном иммунотерапии злокачественных опухолей
|
|
GB201604953D0
(en)
|
2016-03-23 |
2016-05-04 |
Immunocore Ltd |
T cell receptors
|
|
KR102523449B1
(ko)
|
2016-04-08 |
2023-04-19 |
어댑티뮨 리미티드 |
T 세포 수용체
|
|
KR20190059874A
(ko)
|
2016-04-08 |
2019-05-31 |
어댑티뮨 리미티드 |
T 세포 수용체
|
|
RU2018138837A
(ru)
|
2016-04-08 |
2020-05-12 |
Адаптимьюн Лимитед |
Т-клеточные рецепторы
|
|
MA44608B1
(fr)
|
2016-04-08 |
2022-06-30 |
Immunocore Ltd |
Récepteurs des lymphocytes t
|
|
EP3443123B1
(de)
*
|
2016-04-11 |
2021-08-11 |
Board of Regents, The University of Texas System |
Verfahren und zusammensetzungen zum nachweis der affinität einzelner t-zellrezeptoren und sequenz
|
|
AU2017254477A1
(en)
|
2016-04-18 |
2018-11-01 |
Jennifer G. ABELIN |
Improved HLA epitope prediction
|
|
US11827688B2
(en)
|
2016-06-02 |
2023-11-28 |
Immunocore Limited |
Dosing regimen for GP100-specific TCR—anti-CD3 SCFV fusion protein
|
|
EP3475706B1
(de)
|
2016-06-27 |
2021-08-11 |
Juno Therapeutics, Inc. |
Mhc-e-beschränkte epitopen, bindungsmoleküle, und zugehörige verfahren und verwendungen
|
|
US20200182884A1
(en)
|
2016-06-27 |
2020-06-11 |
Juno Therapeutics, Inc. |
Method of identifying peptide epitopes, molecules that bind such epitopes and related uses
|
|
WO2018035364A1
(en)
|
2016-08-17 |
2018-02-22 |
The Broad Institute Inc. |
Product and methods useful for modulating and evaluating immune responses
|
|
US20190262399A1
(en)
|
2016-09-07 |
2019-08-29 |
The Broad Institute, Inc. |
Compositions and methods for evaluating and modulating immune responses
|
|
US10428325B1
(en)
|
2016-09-21 |
2019-10-01 |
Adaptive Biotechnologies Corporation |
Identification of antigen-specific B cell receptors
|
|
BR112019005748A2
(pt)
|
2016-09-24 |
2019-06-18 |
Abvitro Llc |
afinidade-conjugados de oligonucleotídeo e usos destes
|
|
WO2018064208A1
(en)
|
2016-09-28 |
2018-04-05 |
The Broad Institute, Inc. |
Systematic screening and mapping of regulatory elements in non-coding genomic regions, methods, compositions, and applications thereof
|
|
EP3519433A1
(de)
|
2016-10-03 |
2019-08-07 |
Juno Therapeutics, Inc. |
Hpv-spezifische bindungsmoleküle
|
|
WO2018067991A1
(en)
|
2016-10-07 |
2018-04-12 |
The Brigham And Women's Hospital, Inc. |
Modulation of novel immune checkpoint targets
|
|
MA46717A
(fr)
*
|
2016-10-11 |
2019-09-11 |
Bluebird Bio Inc |
Variantes de l'endonucléase homing tcra
|
|
ES2939646T3
(es)
|
2016-10-13 |
2023-04-25 |
Juno Therapeutics Inc |
Métodos y composiciones de inmunoterapia que comprenden moduladores de la vía metabólica del triptófano
|
|
GB2573406B
(en)
|
2016-10-18 |
2021-11-10 |
Univ Minnesota |
Tumor infiltrating lymphocytes and methods of therapy
|
|
MA46783A
(fr)
|
2016-11-03 |
2019-09-11 |
Juno Therapeutics Inc |
Polythérapie de type thérapie cellulaire t et inhibiteur de btk
|
|
CA3040914A1
(en)
|
2016-11-03 |
2018-05-24 |
Juno Therapeutics, Inc. |
Combination therapy of a cell based therapy and a microglia inhibitor
|
|
EP3535288A1
(de)
|
2016-11-07 |
2019-09-11 |
Immunocore Limited |
Peptide
|
|
WO2018089386A1
(en)
|
2016-11-11 |
2018-05-17 |
The Broad Institute, Inc. |
Modulation of intestinal epithelial cell differentiation, maintenance and/or function through t cell action
|
|
JP7685735B2
(ja)
|
2016-12-02 |
2025-05-30 |
アンヘレス セラピューティクス インコーポレイテッド |
合成免疫受容体およびその使用方法
|
|
CN113786476A
(zh)
|
2016-12-02 |
2021-12-14 |
泰加生物工艺学公司 |
纳米颗粒调配物
|
|
MA46995A
(fr)
|
2016-12-03 |
2019-10-09 |
Acerta Pharma Bv |
Méthodes et compositions pour l'utilisation de lymphocytes t thérapeutiques en association avec des inhibiteurs de kinase
|
|
US20200078400A1
(en)
|
2016-12-03 |
2020-03-12 |
Juno Therapeutics, Inc. |
Methods for determining car-t cells dosing
|
|
US20190358262A1
(en)
|
2016-12-03 |
2019-11-28 |
Juno Therapeutics, Inc. |
Methods for modulation of car-t cells
|
|
MA46998A
(fr)
|
2016-12-05 |
2019-10-09 |
Juno Therapeutics Inc |
Production de cellules modifiées pour une thérapie cellulaire adoptive
|
|
JP7429338B2
(ja)
|
2017-01-10 |
2024-02-08 |
ジュノー セラピューティクス インコーポレイテッド |
細胞療法および関連方法のエピジェネティック解析
|
|
AU2018207172B2
(en)
|
2017-01-13 |
2023-10-12 |
Mink Therapeutics, Inc. |
T cell receptors that bind to NY-ESO-1 and methods of use thereof
|
|
CA3050085A1
(en)
|
2017-01-20 |
2018-07-26 |
Juno Therapeutics Gmbh |
Cell surface conjugates and related cell compositions and methods
|
|
US11549149B2
(en)
|
2017-01-24 |
2023-01-10 |
The Broad Institute, Inc. |
Compositions and methods for detecting a mutant variant of a polynucleotide
|
|
JP7082424B2
(ja)
|
2017-01-25 |
2022-06-08 |
モレキュラー テンプレーツ,インク. |
脱免疫化された志賀毒素aサブユニットエフェクター及びcd8+t細胞エピトープを含む細胞標的化分子
|
|
WO2018148180A2
(en)
|
2017-02-07 |
2018-08-16 |
Immune Design Corp. |
Materials and methods for identifying and treating cancer patients
|
|
CN116693695A
(zh)
|
2017-02-12 |
2023-09-05 |
百欧恩泰美国公司 |
基于hla的方法和组合物及其用途
|
|
JP2020507605A
(ja)
|
2017-02-17 |
2020-03-12 |
フレッド ハッチンソン キャンサー リサーチ センター |
Bcma関連癌および自己免疫疾患の治療のための併用療法
|
|
CA3053539A1
(en)
|
2017-02-27 |
2018-08-30 |
Juno Therapeutics, Inc. |
Compositions, articles of manufacture and methods related to dosing in cell therapy
|
|
BR112019019005A2
(pt)
|
2017-03-14 |
2020-04-14 |
Sara Elizabeth Church |
métodos para armazenagem criogênica
|
|
US11963966B2
(en)
|
2017-03-31 |
2024-04-23 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating ovarian tumors
|
|
US11913075B2
(en)
|
2017-04-01 |
2024-02-27 |
The Broad Institute, Inc. |
Methods and compositions for detecting and modulating an immunotherapy resistance gene signature in cancer
|
|
CA3056261A1
(en)
|
2017-04-07 |
2018-10-11 |
Juno Therapeutics, Inc. |
Engineered cells expressing prostate-specific membrane antigen (psma) or a modified form thereof and related methods
|
|
WO2018191558A1
(en)
|
2017-04-12 |
2018-10-18 |
The Broad Institute, Inc. |
Modulation of epithelial cell differentiation, maintenance and/or function through t cell action, and markers and methods of use thereof
|
|
US20200071773A1
(en)
|
2017-04-12 |
2020-03-05 |
Massachusetts Eye And Ear Infirmary |
Tumor signature for metastasis, compositions of matter methods of use thereof
|
|
CN110709700A
(zh)
|
2017-04-14 |
2020-01-17 |
朱诺治疗学股份有限公司 |
评估细胞表面糖基化的方法
|
|
EP3612629A1
(de)
|
2017-04-18 |
2020-02-26 |
The Broad Institute, Inc. |
Zusammensetzungen zur erkennung von sekretion und verwendungsverfahren
|
|
KR20240139092A
(ko)
|
2017-05-01 |
2024-09-20 |
주노 쎄러퓨티크스 인코퍼레이티드 |
세포 요법 및 면역조절 화합물의 조합
|
|
WO2019103857A1
(en)
|
2017-11-22 |
2019-05-31 |
Iovance Biotherapeutics, Inc. |
Expansion of peripheral blood lymphocytes (pbls) from peripheral blood
|
|
WO2018209324A2
(en)
|
2017-05-11 |
2018-11-15 |
The Broad Institute, Inc. |
Methods and compositions of use of cd8+ tumor infiltrating lymphocyte subtypes and gene signatures thereof
|
|
US12297436B2
(en)
|
2017-05-18 |
2025-05-13 |
The Broad Institute, Inc. |
Systems, methods, and compositions for targeted nucleic acid editing
|
|
MA49352A
(fr)
|
2017-05-26 |
2020-04-08 |
Abvitro Llc |
Séquençage de bibliothèque de polynucléotides à haut rendement et analyse de transcriptome
|
|
CN111225675B
(zh)
|
2017-06-02 |
2024-05-03 |
朱诺治疗学股份有限公司 |
使用过继细胞疗法治疗的制品和方法
|
|
AU2018275891B2
(en)
|
2017-06-02 |
2025-02-27 |
Juno Therapeutics, Inc. |
Articles of manufacture and methods related to toxicity associated with cell therapy
|
|
WO2018232195A1
(en)
|
2017-06-14 |
2018-12-20 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
|
GB201709866D0
(en)
|
2017-06-20 |
2017-08-02 |
Immunocore Ltd |
T cell receptors
|
|
EP3644721A1
(de)
|
2017-06-29 |
2020-05-06 |
Juno Therapeutics, Inc. |
Mausmodell zur auswertung von toxizitäten im zusammenhang mit immunotherapien
|
|
JP2020530307A
(ja)
|
2017-06-30 |
2020-10-22 |
インティマ・バイオサイエンス,インコーポレーテッド |
遺伝子治療のためのアデノ随伴ウイルスベクター
|
|
US12049643B2
(en)
|
2017-07-14 |
2024-07-30 |
The Broad Institute, Inc. |
Methods and compositions for modulating cytotoxic lymphocyte activity
|
|
KR20200064060A
(ko)
|
2017-07-29 |
2020-06-05 |
주노 쎄러퓨티크스 인코퍼레이티드 |
재조합 수용체를 발현하는 세포 증폭용 시약
|
|
EP3490584B1
(de)
|
2017-08-03 |
2021-12-08 |
Taiga Biotechnologies, Inc. |
Verfahren und zusammensetzungen zur behandlung von melanom
|
|
US10149898B2
(en)
|
2017-08-03 |
2018-12-11 |
Taiga Biotechnologies, Inc. |
Methods and compositions for the treatment of melanoma
|
|
AU2018313950A1
(en)
|
2017-08-09 |
2020-02-13 |
Juno Therapeutics, Inc. |
Methods for producing genetically engineered cell compositions and related compositions
|
|
CA3070575A1
(en)
|
2017-08-09 |
2019-02-14 |
Juno Therapeutics, Inc. |
Methods and compositions for preparing genetically engineered cells
|
|
US20210071258A1
(en)
|
2017-09-01 |
2021-03-11 |
Juno Therapeutics, Inc. |
Gene expression and assessment of risk of developing toxicity following cell therapy
|
|
JP7387585B2
(ja)
|
2017-09-04 |
2023-11-28 |
アジェナス インコーポレイテッド |
混合系統白血病(mll)特異的ホスホペプチドに結合するt細胞受容体およびその使用方法
|
|
MA50079A
(fr)
|
2017-09-07 |
2020-07-15 |
Juno Therapeutics Inc |
Procédés d'identification de caractéristiques cellulaires relatives à des réponses associées à une thérapie cellulaire
|
|
AU2018338318B2
(en)
|
2017-09-21 |
2022-12-22 |
Massachusetts Institute Of Technology |
Systems, methods, and compositions for targeted nucleic acid editing
|
|
MA50188A
(fr)
*
|
2017-09-22 |
2021-06-02 |
Wuxi Biologics Ireland Ltd |
Nouveaux complexes polypeptidiques bispécifiques
|
|
WO2019057124A1
(en)
|
2017-09-22 |
2019-03-28 |
Wuxi Biologics (Shanghai) Co., Ltd. |
NEW BISPECIFIC CD3 / CD19 POLYPEPTIDE COMPLEXES
|
|
WO2019070755A1
(en)
|
2017-10-02 |
2019-04-11 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS FOR DETECTING AND MODULATING A GENETIC SIGNATURE OF IMMUNOTHERAPY RESISTANCE IN CANCER
|
|
EP3692063A1
(de)
|
2017-10-03 |
2020-08-12 |
Juno Therapeutics, Inc. |
Hpv-spezifische bindungsmoleküle
|
|
US11732257B2
(en)
|
2017-10-23 |
2023-08-22 |
Massachusetts Institute Of Technology |
Single cell sequencing libraries of genomic transcript regions of interest in proximity to barcodes, and genotyping of said libraries
|
|
WO2019089848A1
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Methods associated with tumor burden for assessing response to a cell therapy
|
|
WO2019089982A1
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Method of assessing activity of recombinant antigen receptors
|
|
US12031975B2
(en)
|
2017-11-01 |
2024-07-09 |
Juno Therapeutics, Inc. |
Methods of assessing or monitoring a response to a cell therapy
|
|
MA50855A
(fr)
|
2017-11-01 |
2020-09-09 |
Juno Therapeutics Inc |
Procédé de génération de compositions thérapeutiques de cellules modifiées
|
|
MA50859A
(fr)
|
2017-11-01 |
2020-09-09 |
Celgene Corp |
Procédé pour la production d'une composition de lymphocytes t
|
|
EP3706754A1
(de)
|
2017-11-06 |
2020-09-16 |
Juno Therapeutics, Inc. |
Kombination einer zelltherapie und eines gamma-sekretase-inhibitors
|
|
EP3710039A4
(de)
|
2017-11-13 |
2021-08-04 |
The Broad Institute, Inc. |
Verfahren und zusammensetzungen zur behandlung von krebs durch targeting des clec2d-klrb1-wegs
|
|
WO2019094955A1
(en)
|
2017-11-13 |
2019-05-16 |
The Broad Institute, Inc. |
Methods and compositions for targeting developmental and oncogenic programs in h3k27m gliomas
|
|
US11254980B1
(en)
|
2017-11-29 |
2022-02-22 |
Adaptive Biotechnologies Corporation |
Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements
|
|
KR20200116081A
(ko)
|
2017-12-01 |
2020-10-08 |
주노 쎄러퓨티크스 인코퍼레이티드 |
유전자 조작된 세포의 투약 및 조절 방법
|
|
EP3720480A2
(de)
|
2017-12-08 |
2020-10-14 |
Juno Therapeutics, Inc. |
Phänotypische marker für zelltherapie und verwandte verfahren
|
|
JP7433230B2
(ja)
|
2017-12-08 |
2024-02-19 |
ジュノー セラピューティクス インコーポレイテッド |
細胞を培養するための無血清培地配合物およびその使用の方法
|
|
CA3084445A1
(en)
|
2017-12-08 |
2019-06-13 |
Juno Therapeutics, Inc. |
Process for producing a composition of engineered t cells
|
|
US11994512B2
(en)
|
2018-01-04 |
2024-05-28 |
Massachusetts Institute Of Technology |
Single-cell genomic methods to generate ex vivo cell systems that recapitulate in vivo biology with improved fidelity
|
|
EP3747456A4
(de)
*
|
2018-01-31 |
2021-12-01 |
Tohoku University |
Verfahren zur regulierung der antigenspezifischen mhc-expression
|
|
WO2019152743A1
(en)
|
2018-01-31 |
2019-08-08 |
Celgene Corporation |
Combination therapy using adoptive cell therapy and checkpoint inhibitor
|
|
EP4424710A3
(de)
|
2018-02-26 |
2025-01-15 |
Medigene Immunotherapies GmbH |
Nyeso-tcr
|
|
AU2019247199A1
(en)
|
2018-04-05 |
2020-10-15 |
Editas Medicine, Inc. |
T cells expressing a recombinant receptor, related polynucleotides and methods
|
|
CN112566698A
(zh)
|
2018-04-05 |
2021-03-26 |
朱诺治疗学股份有限公司 |
T细胞受体和表达该t细胞受体的工程化细胞
|
|
EP3775238A1
(de)
|
2018-04-05 |
2021-02-17 |
Juno Therapeutics, Inc. |
Verfahren zur herstellung von zellen, die einen rekombinanten rezeptor exprimieren, und verwandte zusammensetzungen
|
|
EP3773632A4
(de)
|
2018-04-06 |
2022-05-18 |
The Regents of The University of California |
Verfahren zur behandlung von egfrviii-exprimierenden glioblastomen
|
|
CA3095757A1
(en)
|
2018-04-06 |
2019-10-10 |
The Regents Of The University Of California |
Methods of treating glioblastomas
|
|
US11957695B2
(en)
|
2018-04-26 |
2024-04-16 |
The Broad Institute, Inc. |
Methods and compositions targeting glucocorticoid signaling for modulating immune responses
|
|
US20210363216A1
(en)
|
2018-05-14 |
2021-11-25 |
Immunocore Limited |
Bifunctional binding polypeptides
|
|
US20210371932A1
(en)
|
2018-06-01 |
2021-12-02 |
Massachusetts Institute Of Technology |
Methods and compositions for detecting and modulating microenvironment gene signatures from the csf of metastasis patients
|
|
US12036240B2
(en)
|
2018-06-14 |
2024-07-16 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
|
WO2020030631A1
(en)
|
2018-08-06 |
2020-02-13 |
Medigene Immunotherapies Gmbh |
Ha-1 specific t cell receptors and their use
|
|
CN110818802B
(zh)
*
|
2018-08-08 |
2022-02-08 |
华夏英泰(北京)生物技术有限公司 |
一种嵌合t细胞受体star及其应用
|
|
SG11202101204TA
(en)
|
2018-08-09 |
2021-03-30 |
Juno Therapeutics Inc |
Processes for generating engineered cells and compositions thereof
|
|
BR112021002245A2
(pt)
|
2018-08-09 |
2021-05-04 |
Juno Therapeutics Inc |
métodos para avaliar ácidos nucleicos integrados
|
|
WO2020037239A1
(en)
|
2018-08-16 |
2020-02-20 |
Neon Therapeutics, Inc. |
T cell receptor constructs and uses thereof
|
|
US12391685B2
(en)
|
2018-08-20 |
2025-08-19 |
The Broad Institute, Inc. |
Inhibitors of RNA-guided nuclease target binding and uses thereof
|
|
US12460244B2
(en)
|
2018-08-20 |
2025-11-04 |
The Broad Institute, Inc. |
Inhibitors of RNA-guided nuclease activity and uses thereof
|
|
US20210324357A1
(en)
|
2018-08-20 |
2021-10-21 |
The Brigham And Women's Hospital, Inc. |
Degradation domain modifications for spatio-temporal control of rna-guided nucleases
|
|
MX2021002574A
(es)
|
2018-09-11 |
2021-06-08 |
Juno Therapeutics Inc |
Metodos para el analisis por espectrometria de masas de composiciones de celulas modificadas.
|
|
GB201815041D0
(en)
|
2018-09-14 |
2018-10-31 |
Scancell Ltd |
Epitopes
|
|
WO2020072700A1
(en)
|
2018-10-02 |
2020-04-09 |
Dana-Farber Cancer Institute, Inc. |
Hla single allele lines
|
|
WO2020081730A2
(en)
|
2018-10-16 |
2020-04-23 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating microenvironment
|
|
WO2020092455A2
(en)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
Car t cell transcriptional atlas
|
|
EP3874024A1
(de)
|
2018-10-31 |
2021-09-08 |
Juno Therapeutics GmbH |
Verfahren zur selektion und stimulation von zellen und vorrichtung dafür
|
|
JP7604366B2
(ja)
|
2018-11-06 |
2024-12-23 |
ジュノー セラピューティクス インコーポレイテッド |
遺伝子操作されたt細胞を作製するための方法
|
|
EP3876956A4
(de)
|
2018-11-08 |
2022-12-28 |
The Regents of The University of California |
Systeme und verfahren zum targeting von krebszellen
|
|
CA3117978A1
(en)
|
2018-11-08 |
2020-05-14 |
Juno Therapeutics, Inc. |
Methods and combinations for treatment and t cell modulation
|
|
BR112021010354A2
(pt)
|
2018-11-30 |
2021-11-03 |
Juno Therapeutics Inc |
Métodos para o tratamento usando terapia celular adotiva
|
|
SG11202105380RA
(en)
|
2018-11-30 |
2021-06-29 |
Juno Therapeutics Inc |
Methods for dosing and treatment of b cell malignancies in adoptive cell therapy
|
|
US20220062394A1
(en)
|
2018-12-17 |
2022-03-03 |
The Broad Institute, Inc. |
Methods for identifying neoantigens
|
|
AU2019404547B2
(en)
|
2018-12-21 |
2025-01-30 |
Biontech Us Inc. |
Method and systems for prediction of HLA class II-specific epitopes and characterization of CD4+ T cells
|
|
US11739156B2
(en)
|
2019-01-06 |
2023-08-29 |
The Broad Institute, Inc. Massachusetts Institute of Technology |
Methods and compositions for overcoming immunosuppression
|
|
TWI852977B
(zh)
|
2019-01-10 |
2024-08-21 |
美商健生生物科技公司 |
前列腺新抗原及其用途
|
|
HUE065436T2
(hu)
|
2019-01-17 |
2024-06-28 |
Immunocore Ltd |
Kiszerelések
|
|
WO2020156405A1
(en)
*
|
2019-01-28 |
2020-08-06 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Novel bispecific cd3/cd20 polypeptide complexes
|
|
GB201901306D0
(en)
|
2019-01-30 |
2019-03-20 |
Immunocore Ltd |
Multi-domain binding molecules
|
|
GB201901305D0
(en)
|
2019-01-30 |
2019-03-20 |
Immunocore Ltd |
Specific binding molecules
|
|
KR20210136050A
(ko)
|
2019-03-01 |
2021-11-16 |
이오반스 바이오테라퓨틱스, 인크. |
액상 종양으로부터의 종양 침윤 림프구의 확장 및 그의 치료 용도
|
|
WO2020186101A1
(en)
|
2019-03-12 |
2020-09-17 |
The Broad Institute, Inc. |
Detection means, compositions and methods for modulating synovial sarcoma cells
|
|
WO2020188348A2
(en)
|
2019-03-18 |
2020-09-24 |
Ludwig Institute For Cancer Research Ltd |
A2/ny-eso-1 specific t cell receptors and uses thereof
|
|
EP3942023A1
(de)
|
2019-03-18 |
2022-01-26 |
The Broad Institute, Inc. |
Zusammensetzungen und verfahren zur modulation metabolischer regulatoren der t-zell-pathogenität
|
|
WO2020191365A1
(en)
|
2019-03-21 |
2020-09-24 |
Gigamune, Inc. |
Engineered cells expressing anti-viral t cell receptors and methods of use thereof
|
|
EP3714941A1
(de)
|
2019-03-27 |
2020-09-30 |
Medigene Immunotherapies GmbH |
Mage-a4-tcrs
|
|
GB201904328D0
(en)
|
2019-03-28 |
2019-05-15 |
Immunocore Ltd |
Specific binding molecules
|
|
TWI850360B
(zh)
|
2019-04-04 |
2024-08-01 |
德商梅迪基因免疫治療公司 |
黑色素瘤相關抗原1(magea1)特異性t細胞受體及其用途
|
|
CN113874033A
(zh)
|
2019-04-08 |
2021-12-31 |
泰加生物工艺学公司 |
用于冷冻保存免疫细胞的组合物和方法
|
|
AU2020265741A1
(en)
|
2019-05-01 |
2021-11-25 |
Editas Medicine, Inc. |
Cells expressing a recombinant receptor from a modified TGFBR2 Locus, related polynucleotides and methods
|
|
MX2021013588A
(es)
|
2019-05-08 |
2022-02-11 |
Medigene Immunotherapies Gmbh |
Células t genomodificadas.
|
|
JP2022532608A
(ja)
|
2019-05-14 |
2022-07-15 |
タイガ バイオテクノロジーズ,インク. |
T細胞疲弊を処置するための組成物および方法
|
|
EA202193121A1
(ru)
|
2019-05-15 |
2022-02-21 |
Неоткс Терапьютикс Лтд. |
Лечение рака
|
|
US20220235340A1
(en)
|
2019-05-20 |
2022-07-28 |
The Broad Institute, Inc. |
Novel crispr-cas systems and uses thereof
|
|
WO2020243371A1
(en)
|
2019-05-28 |
2020-12-03 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating immune responses
|
|
MX2021015125A
(es)
|
2019-06-07 |
2022-04-06 |
Juno Therapeutics Inc |
Cultivo automatizado de celulas t.
|
|
US20220249637A1
(en)
|
2019-06-12 |
2022-08-11 |
Juno Therapeutics, Inc. |
Combination therapy of a cell-mediated cytotoxic therapy and an inhibitor of a prosurvival bcl2 family protein
|
|
EP3997116A1
(de)
|
2019-07-09 |
2022-05-18 |
Medigene Immunotherapies GmbH |
Magea10-spezifische t-zell-rezeptoren und deren verwendung
|
|
US12480958B2
(en)
|
2019-08-13 |
2025-11-25 |
Immatics Biotechnologies Gmbh |
Method for the characterization of peptide:MHC binding polypeptides
|
|
WO2021030627A1
(en)
|
2019-08-13 |
2021-02-18 |
The General Hospital Corporation |
Methods for predicting outcomes of checkpoint inhibition and treatment thereof
|
|
US12421557B2
(en)
|
2019-08-16 |
2025-09-23 |
The Broad Institute, Inc. |
Methods for predicting outcomes and treating colorectal cancer using a cell atlas
|
|
CN114555112A
(zh)
|
2019-08-22 |
2022-05-27 |
朱诺治疗学股份有限公司 |
T细胞疗法和zeste增强子同源物2(ezh2)抑制剂的组合疗法及相关方法
|
|
WO2021041922A1
(en)
|
2019-08-30 |
2021-03-04 |
The Broad Institute, Inc. |
Crispr-associated mu transposase systems
|
|
EP4025598A1
(de)
|
2019-09-06 |
2022-07-13 |
Eli Lilly and Company |
Proteine mit konstanten domänen des t-zell-rezeptors
|
|
US12297426B2
(en)
|
2019-10-01 |
2025-05-13 |
The Broad Institute, Inc. |
DNA damage response signature guided rational design of CRISPR-based systems and therapies
|
|
US12394502B2
(en)
|
2019-10-02 |
2025-08-19 |
The General Hospital Corporation |
Method for predicting HLA-binding peptides using protein structural features
|
|
US11981922B2
(en)
|
2019-10-03 |
2024-05-14 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for the modulation of cell interactions and signaling in the tumor microenvironment
|
|
US12195725B2
(en)
|
2019-10-03 |
2025-01-14 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for modulating and detecting tissue specific TH17 cell pathogenicity
|
|
US11793787B2
(en)
|
2019-10-07 |
2023-10-24 |
The Broad Institute, Inc. |
Methods and compositions for enhancing anti-tumor immunity by targeting steroidogenesis
|
|
GB201915282D0
(en)
|
2019-10-22 |
2019-12-04 |
Immunocore Ltd |
Specific binding molecules
|
|
US11844800B2
(en)
|
2019-10-30 |
2023-12-19 |
Massachusetts Institute Of Technology |
Methods and compositions for predicting and preventing relapse of acute lymphoblastic leukemia
|
|
WO2021084050A1
(en)
|
2019-10-30 |
2021-05-06 |
Juno Therapeutics Gmbh |
Cell selection and/or stimulation devices and methods of use
|
|
US12195723B2
(en)
|
2019-11-08 |
2025-01-14 |
The Broad Institute, Inc. |
Engineered antigen presenting cells and uses thereof
|
|
KR20220097492A
(ko)
|
2019-11-12 |
2022-07-07 |
옥스포드 바이오메디카(유케이) 리미티드 |
생산 시스템
|
|
CN114980920A
(zh)
|
2019-11-18 |
2022-08-30 |
詹森生物科技公司 |
基于突变体calr和jak2的疫苗及其用途
|
|
WO2021113770A1
(en)
|
2019-12-06 |
2021-06-10 |
Juno Therapeutics, Inc. |
Methods related to toxicity and response associated with cell therapy for treating b cell malignancies
|
|
US11865168B2
(en)
|
2019-12-30 |
2024-01-09 |
Massachusetts Institute Of Technology |
Compositions and methods for treating bacterial infections
|
|
US12165747B2
(en)
|
2020-01-23 |
2024-12-10 |
The Broad Institute, Inc. |
Molecular spatial mapping of metastatic tumor microenvironment
|
|
KR20220146480A
(ko)
|
2020-01-28 |
2022-11-01 |
주노 쎄러퓨티크스 인코퍼레이티드 |
T 세포 형질도입 방법
|
|
TW202144389A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在多發性骨髓瘤中表現之新抗原及其用途
|
|
TW202144388A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在卵巢癌中表現之新抗原及其用途
|
|
AU2021357520A1
(en)
|
2020-03-05 |
2022-09-29 |
Neotx Therapeutics Ltd. |
Methods and compositions for treating cancer with immune cells
|
|
WO2021190580A1
(en)
*
|
2020-03-26 |
2021-09-30 |
Wuxi Biologics (Shanghai) Co., Ltd. |
Bispecific polypeptide complexes, compositions, and methods of preparation and use
|
|
JP2023515270A
(ja)
|
2020-04-21 |
2023-04-12 |
テンパス・ラボズ・インコーポレイテッド |
Tcr/bcrプロファイリング
|
|
GB202005779D0
(en)
|
2020-04-21 |
2020-06-03 |
Scancell Ltd |
Anti-tumour immune responses
|
|
GB202006629D0
(en)
|
2020-05-05 |
2020-06-17 |
Immunocore Ltd |
Specific binding molecules
|
|
WO2021231657A1
(en)
|
2020-05-13 |
2021-11-18 |
Juno Therapeutics, Inc. |
Methods of identifying features associated with clinical response and uses thereof
|
|
KR20230022868A
(ko)
|
2020-05-13 |
2023-02-16 |
주노 쎄러퓨티크스 인코퍼레이티드 |
재조합 수용체를 발현하는 공여자-배치 세포의 제조 방법
|
|
WO2021260186A1
(en)
|
2020-06-26 |
2021-12-30 |
Juno Therapeutics Gmbh |
Engineered t cells conditionally expressing a recombinant receptor, related polynucleotides and methods
|
|
GB202010329D0
(en)
|
2020-07-06 |
2020-08-19 |
Immunocore Ltd |
Specific binding molecules
|
|
WO2022009052A2
(en)
|
2020-07-06 |
2022-01-13 |
Janssen Biotech, Inc. |
Prostate neoantigens and their uses
|
|
WO2022060904A1
(en)
|
2020-09-16 |
2022-03-24 |
Obsidian Therapeutics, Inc. |
Compositions and methods for expression of t-cell receptors with small molecule-regulated cd40l in t cells
|
|
US20230340064A1
(en)
|
2020-09-24 |
2023-10-26 |
Medigene Immunotherapies Gmbh |
Mage-a3 specific t cell receptors and their use
|
|
US12024559B2
(en)
|
2020-10-23 |
2024-07-02 |
Asher Biotherapeutics, Inc. |
Fusions with CD8 antigen binding molecules for modulating immune cell function
|
|
GB202018395D0
(en)
|
2020-11-23 |
2021-01-06 |
Scancell Ltd |
Immunotherapy
|
|
AU2021389909A1
(en)
|
2020-11-24 |
2023-06-22 |
Shanghai GenBase Biotechnology Co., Ltd. |
Ras mutant epitope peptide and t cell receptor recognizing ras mutant
|
|
GB202019019D0
(en)
|
2020-12-02 |
2021-01-13 |
Univ Oxford Innovation Ltd |
T cell receptors and uses thereof
|
|
WO2022133030A1
(en)
|
2020-12-16 |
2022-06-23 |
Juno Therapeutics, Inc. |
Combination therapy of a cell therapy and a bcl2 inhibitor
|
|
US12275766B2
(en)
|
2020-12-23 |
2025-04-15 |
Janssen Biotech, Inc. |
Neoantigen peptide mimics
|
|
EP4281473A4
(de)
*
|
2021-01-19 |
2024-12-18 |
Wuxi Biologics Ireland Limited |
Polypeptidkomplexe mit verbesserter stabilität und expression
|
|
EP4293043A4
(de)
|
2021-02-10 |
2025-09-10 |
Shanghai Genbase Biotechnology Co Ltd |
Epitoppeptid eines ras-g13d-mutants und t-zell-rezeptor zur erkennung eines ras-g13d-mutants
|
|
IL305393A
(en)
|
2021-02-25 |
2023-10-01 |
Alaunos Therapeutics Inc |
Recombinant vectors comprising polycistronic expression cassettes and methods of use thereof
|
|
WO2022187280A1
(en)
|
2021-03-01 |
2022-09-09 |
Dana-Farber Cancer Institute, Inc. |
Personalized redirection and reprogramming of t cells for precise targeting of tumors
|
|
WO2022187406A1
(en)
|
2021-03-03 |
2022-09-09 |
Juno Therapeutics, Inc. |
Combination of a t cell therapy and a dgk inhibitor
|
|
KR20230159851A
(ko)
|
2021-03-22 |
2023-11-22 |
주노 쎄러퓨티크스 인코퍼레이티드 |
치료 세포 조성물의 효력을 결정하는 방법
|
|
WO2022212400A1
(en)
|
2021-03-29 |
2022-10-06 |
Juno Therapeutics, Inc. |
Methods for dosing and treatment with a combination of a checkpoint inhibitor therapy and a car t cell therapy
|
|
US12376573B2
(en)
|
2021-03-31 |
2025-08-05 |
Regeneron Pharmaceuticals, Inc. |
Genetically modified mice comprising humanized cellular immune system components with improved diversity of TCRB repertoire
|
|
BR112023022765A2
(pt)
|
2021-05-05 |
2024-01-02 |
Immatics Biotechnologies Gmbh |
Proteínas de ligação ao antígeno que ligam especificamente o prame
|
|
JP2024517863A
(ja)
|
2021-05-06 |
2024-04-23 |
ジュノ・セラピューティクス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
細胞を刺激し、形質導入する方法
|
|
WO2023288203A2
(en)
|
2021-07-12 |
2023-01-19 |
Ludwig Institute For Cancer Research Ltd |
T cell receptors specific for tumor-associated antigens and methods of use thereof
|
|
KR20240114759A
(ko)
|
2021-12-01 |
2024-07-24 |
이뮤노코어 리미티드 |
치료
|
|
WO2023099606A1
(en)
|
2021-12-01 |
2023-06-08 |
Immunocore Limited |
Treatment of mage-a4 positive cancer
|
|
WO2023147515A1
(en)
|
2022-01-28 |
2023-08-03 |
Juno Therapeutics, Inc. |
Methods of manufacturing cellular compositions
|
|
US20250145950A1
(en)
|
2022-02-01 |
2025-05-08 |
Alaunos Therapeutics, Inc. |
Methods for Activation and Expansion of T Cells
|
|
AU2023222190A1
(en)
|
2022-02-20 |
2024-08-29 |
Immunocore Limited |
Hiv-specific binding molecules and tcr
|
|
WO2023183344A1
(en)
|
2022-03-21 |
2023-09-28 |
Alaunos Therapeutics, Inc. |
Methods for identifying neoantigen-reactive t cell receptors
|
|
WO2023213969A1
(en)
|
2022-05-05 |
2023-11-09 |
Juno Therapeutics Gmbh |
Viral-binding protein and related reagents, articles, and methods of use
|
|
US20250345432A1
(en)
|
2022-05-25 |
2025-11-13 |
Celgene Corporation |
Method for predicting response to a t cell therapy
|
|
WO2024006960A1
(en)
|
2022-06-29 |
2024-01-04 |
Juno Therapeutics, Inc. |
Lipid nanoparticles for delivery of nucleic acids
|
|
JP2025527575A
(ja)
|
2022-08-18 |
2025-08-22 |
イミュノコア リミテッド |
Mage a4に特異的なt細胞受容体融合タンパク質
|
|
MX2025001960A
(es)
|
2022-08-18 |
2025-05-02 |
Immunocore Ltd |
Moléculas de unión multidominio
|
|
IL318931A
(en)
|
2022-08-18 |
2025-04-01 |
Immunocore Ltd |
Multi-domain binding molecules
|
|
EP4572779A1
(de)
|
2022-08-18 |
2025-06-25 |
Immunocore Ltd |
Multidomänenbindende moleküle
|
|
WO2024050399A1
(en)
|
2022-09-01 |
2024-03-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Single domain antibodies targeting hpv e6/e7 oncogenic peptide/mhc complexes
|
|
WO2024054944A1
(en)
|
2022-09-08 |
2024-03-14 |
Juno Therapeutics, Inc. |
Combination of a t cell therapy and continuous or intermittent dgk inhibitor dosing
|
|
WO2024077256A1
(en)
|
2022-10-07 |
2024-04-11 |
The General Hospital Corporation |
Methods and compositions for high-throughput discovery ofpeptide-mhc targeting binding proteins
|
|
WO2024098024A1
(en)
|
2022-11-04 |
2024-05-10 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
|
|
EP4615960A1
(de)
|
2022-11-09 |
2025-09-17 |
C3S2 GmbH |
Verfahren zur herstellung von manipulierten immunzellen
|
|
WO2024124044A1
(en)
|
2022-12-07 |
2024-06-13 |
The Brigham And Women’S Hospital, Inc. |
Compositions and methods targeting sat1 for enhancing anti¬ tumor immunity during tumor progression
|
|
CN121100267A
(zh)
|
2022-12-09 |
2025-12-09 |
朱诺治疗学股份有限公司 |
使用全息成像预测细胞表型的机器学习方法
|
|
EP4634216A1
(de)
|
2022-12-16 |
2025-10-22 |
Repertoire Immune Medicines, Inc. |
Hpv-16 epitope bindende t-zellrezeptoren
|
|
WO2024146951A1
(en)
|
2023-01-06 |
2024-07-11 |
Immunocore Limited |
Binding molecules against a prame peptide-hla complex
|
|
EP4646268A1
(de)
|
2023-01-06 |
2025-11-12 |
Immunocore Limited |
Bindungsmoleküle gegen einen piwil1-peptid-hla-komplex
|
|
CN121002052A
(zh)
|
2023-02-03 |
2025-11-21 |
C3S2 有限公司 |
用于非病毒生产工程化免疫细胞的方法
|
|
WO2024192141A1
(en)
|
2023-03-13 |
2024-09-19 |
Dana-Farber Cancer Institute, Inc. |
Treatment of cancers having a drug-resistant mesenchymal cell state
|
|
WO2024197072A2
(en)
|
2023-03-21 |
2024-09-26 |
Alaunos Therapeutics, Inc. |
Identification of neoantigen-reactive t cell receptors
|
|
EP4698902A1
(de)
|
2023-04-18 |
2026-02-25 |
Juno Therapeutics, Inc. |
Zytotoxizitätstest zur beurteilung der wirksamkeit von therapeutischen zellzusammensetzungen
|
|
WO2024226838A2
(en)
|
2023-04-25 |
2024-10-31 |
The Brigham And Women's Hospital, Inc. |
Treatment of autoimmune diseases having a pathogenic t cell state
|
|
GB202306345D0
(en)
|
2023-04-28 |
2023-06-14 |
Immunocore Ltd |
Binding molecules
|
|
EP4716851A2
(de)
|
2023-05-23 |
2026-04-01 |
Juno Therapeutics, Inc. |
Aktivierungsmarker von t-zellen und verfahren zur beurteilung der t-zellaktivierung
|
|
GB202311170D0
(en)
|
2023-07-20 |
2023-09-06 |
Univ Oxford Innovation Ltd |
Antigen binding polypeptides
|
|
WO2025040598A2
(en)
|
2023-08-18 |
2025-02-27 |
Immatics Biotechnologies Gmbh |
Peptides displayed by mhc for use in immunotherapy against different types of cancer
|
|
WO2025059533A1
(en)
|
2023-09-13 |
2025-03-20 |
The Broad Institute, Inc. |
Crispr enzymes and systems
|
|
CN122029198A
(zh)
|
2023-11-01 |
2026-05-12 |
英美偌科有限公司 |
用于纯化小的多结构域蛋白质的方法
|
|
WO2025097055A2
(en)
|
2023-11-02 |
2025-05-08 |
The Broad Institute, Inc. |
Compositions and methods of use of t cells in immunotherapy
|
|
WO2025117544A1
(en)
|
2023-11-29 |
2025-06-05 |
The Broad Institute, Inc. |
Engineered omega guide molecule and iscb compositions, systems, and methods of use thereof
|
|
WO2025147545A1
(en)
|
2024-01-03 |
2025-07-10 |
Juno Therapeutics, Inc. |
Lipid nanoparticles for delivery of nucleic acids and related methods and uses
|
|
WO2025208068A2
(en)
*
|
2024-03-29 |
2025-10-02 |
Biontech Us Inc. |
T cell receptor constructs and uses thereof
|
|
WO2025219955A1
(en)
*
|
2024-04-17 |
2025-10-23 |
BioNTech SE |
Soluble tcrs and methods of use thereof
|
|
EP4635976A1
(de)
|
2024-04-19 |
2025-10-22 |
Medigene Immunotherapies GmbH |
Konstante uni-laschen
|
|
WO2025224084A1
(en)
|
2024-04-22 |
2025-10-30 |
Engimmune Therapeutics Ag |
Proteins comprising t cell receptor constant domains
|
|
GB202406990D0
(en)
|
2024-05-16 |
2024-07-03 |
Univ Oxford Innovation Ltd |
T cell receptors and uses thereof
|
|
NL2037811B1
(en)
|
2024-05-29 |
2025-12-12 |
Univ Oslo |
Treatment for Cancer
|
|
GB2641580A
(en)
|
2024-06-07 |
2025-12-10 |
T Therapeutics Ltd |
Tumour-transforming multispecific proteins
|
|
WO2026025092A1
(en)
|
2024-07-26 |
2026-01-29 |
Juno Therapeutics, Inc. |
Synthetic promoters for t cell expression
|
|
WO2026046995A1
(en)
|
2024-08-28 |
2026-03-05 |
Pairx Bio Pte. Ltd |
T cell receptors and uses thereof
|
|
WO2026047601A1
(en)
|
2024-08-28 |
2026-03-05 |
BioNTech SE |
T-cell receptors (tcrs)
|
|
WO2026058153A2
(en)
|
2024-09-10 |
2026-03-19 |
BioNTech SE |
Hpv-16 t cell receptor uses and compositions thereof
|
|
WO2026078231A1
(en)
|
2024-10-11 |
2026-04-16 |
T-Therapeutics Limited |
Soluble non-aggregating immune ligand
|