ATE433317T1 - Medizinische aerosolformulierung von antidiabetika - Google Patents

Medizinische aerosolformulierung von antidiabetika

Info

Publication number
ATE433317T1
ATE433317T1 AT01900300T AT01900300T ATE433317T1 AT E433317 T1 ATE433317 T1 AT E433317T1 AT 01900300 T AT01900300 T AT 01900300T AT 01900300 T AT01900300 T AT 01900300T AT E433317 T1 ATE433317 T1 AT E433317T1
Authority
AT
Austria
Prior art keywords
aerosol formulation
antidiabetic drugs
medical aerosol
medical
medicinal aerosol
Prior art date
Application number
AT01900300T
Other languages
English (en)
Inventor
Akwete Adjei
Anthony Cutie
John Sun
Frederick Sexton
Original Assignee
Aeropharm Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aeropharm Technology Inc filed Critical Aeropharm Technology Inc
Application granted granted Critical
Publication of ATE433317T1 publication Critical patent/ATE433317T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT01900300T 2000-01-25 2001-01-02 Medizinische aerosolformulierung von antidiabetika ATE433317T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17792200P 2000-01-25 2000-01-25
US09/702,939 US6540983B1 (en) 2000-01-25 2000-10-31 Medical aerosol formulation
PCT/US2001/000028 WO2001054741A1 (en) 2000-01-25 2001-01-02 A medicinal aerosol formulation

Publications (1)

Publication Number Publication Date
ATE433317T1 true ATE433317T1 (de) 2009-06-15

Family

ID=26873780

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01900300T ATE433317T1 (de) 2000-01-25 2001-01-02 Medizinische aerosolformulierung von antidiabetika

Country Status (11)

Country Link
US (1) US6540983B1 (de)
EP (1) EP1289573B1 (de)
JP (1) JP2003520829A (de)
CN (1) CN1235641C (de)
AT (1) ATE433317T1 (de)
AU (2) AU2471601A (de)
CA (1) CA2396785C (de)
DE (1) DE60138948D1 (de)
ES (1) ES2328556T3 (de)
MX (1) MXPA02007188A (de)
WO (1) WO2001054741A1 (de)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7074388B2 (en) * 1998-12-10 2006-07-11 Kos Life Science, Inc. Water stabilized medicinal aerosol formulation
US20060171899A1 (en) * 1998-12-10 2006-08-03 Akwete Adjei Water-stabilized aerosol formulation system and method of making
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
EP1494732B1 (de) 2002-03-20 2008-01-30 MannKind Corporation Inhalationsgerät
US20080260838A1 (en) * 2003-08-01 2008-10-23 Mannkind Corporation Glucagon-like peptide 1 (glp-1) pharmaceutical formulations
US7683029B2 (en) * 2003-05-07 2010-03-23 Philip Morris Usa Inc. Liquid aerosol formulations containing insulin and aerosol generating devices and methods for generating aerosolized insulin
US20050143303A1 (en) * 2003-12-26 2005-06-30 Nastech Pharmaceutical Company Inc. Intranasal administration of glucose-regulating peptides
DK1786784T3 (da) 2004-08-20 2011-02-14 Mannkind Corp Katalyse af diketopiperazinsyntese
CN104436170B (zh) 2004-08-23 2018-02-23 曼金德公司 用于药物输送的二酮哌嗪盐
BRPI0614548A2 (pt) * 2005-08-08 2011-03-29 Novartis Ag embalagem isolada para inaladores de dose medida
AU2006290227B2 (en) 2005-09-14 2012-08-02 Mannkind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
KR20080096809A (ko) 2006-02-22 2008-11-03 맨카인드 코포레이션 디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법
US8197404B2 (en) * 2006-12-15 2012-06-12 Ethicon Endo-Surgery, Inc. Handoscopy interwoven layered seal laparoscopic disk
US7819800B2 (en) * 2006-12-15 2010-10-26 Ethicon Endo-Surgery, Inc. Fully automated iris seal for hand assisted laparoscopic surgical procedures
US7967748B2 (en) * 2006-12-15 2011-06-28 Ethicon Endo-Surgery, Inc. Resiliently supported seal cap for hand assisted laparoscopic surgical procedures
KR101736502B1 (ko) * 2007-10-24 2017-05-16 맨카인드 코포레이션 Ｇｌｐ-1에 의한 유해 효과의 예방 방법
EP2060268A1 (de) * 2007-11-15 2009-05-20 Novo Nordisk A/S Pharmazeutische Zusammensetzungen für die Zufuhr von Peptiden über die Lunge oder Nase
CN101980738A (zh) 2008-02-07 2011-02-23 华盛顿大学 圆周气雾设备
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
SG10201507036TA (en) 2008-06-13 2015-10-29 Mannkind Corp A dry powder inhaler and system for drug delivery
EP2609954B1 (de) 2008-06-20 2021-12-29 MannKind Corporation Interaktives Gerät für die Echtzeit-Profilierung von Inhalationsversuchen
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
MX2011009512A (es) 2009-03-11 2011-11-29 Mannkind Corp Aparato, sistema y metodo para medir la resistencia de un inhalador.
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
IL223742A (en) 2010-06-21 2016-06-30 Mannkind Corp A dry powder inhaler and preparation for it
RU2612506C2 (ru) 2011-03-03 2017-03-09 Импел Ньюрофарма Инк. Устройство для назальной доставки лекарственных средств
TWI399202B (zh) 2011-03-17 2013-06-21 Intech Biopharm Ltd 製備用於治療呼吸道疾病之定量噴霧吸入劑的製程方法
EP2694402B1 (de) 2011-04-01 2017-03-22 MannKind Corporation Blisterverpackung für pharmakartuschen
WO2012154859A1 (en) 2011-05-09 2012-11-15 Impel Neuropharma Inc. Nozzles for nasal drug delivery
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
HK1200318A1 (en) 2011-10-24 2015-08-07 曼金德公司 Methods and compositions for treating pain
EP2872205B1 (de) 2012-07-12 2017-02-08 MannKind Corporation System zur verabreichung von arzneimitteln in trockenpulverform
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
US10188617B2 (en) 2013-03-12 2019-01-29 The Board Of Trustees Of The Leland Stanford Junior University Modulation of cellular DNA repair activity to intercept malignancy
WO2014144895A1 (en) 2013-03-15 2014-09-18 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
EP2991713B1 (de) 2013-04-28 2019-06-19 Impel Neuropharma Inc. Medizinischer einzeldosisbehälter
KR102465025B1 (ko) 2013-07-18 2022-11-09 맨카인드 코포레이션 열-안정성 건조 분말 약제학적 조성물 및 방법
EP3030294B1 (de) 2013-08-05 2020-10-07 MannKind Corporation Insufflationsvorrichtung
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CN108498913A (zh) * 2015-05-16 2018-09-07 苏州汉方医药有限公司 一种药物器械组合成的用于治疗糖尿病的药盒
NZ741171A (en) 2015-09-10 2022-01-28 Impel Neuropharma Inc In-line nasal delivery device
EP3713628A4 (de) 2017-11-21 2021-08-18 Impel Neuropharma Inc. Intranasale vorrichtung mit tauchrohr
CA3081680A1 (en) 2017-11-21 2019-05-31 Impel Neuropharma, Inc. Intranasal device with inlet interface
US11278492B2 (en) 2018-01-05 2022-03-22 Impel Neuropharma, Inc. Intranasal delivery of olanzapine by precision olfactory device
JP7317020B2 (ja) 2018-01-05 2023-07-28 インペル ファーマシューティカルズ インコーポレイテッド 精密嗅覚デバイスによるジヒドロエルゴタミンの鼻腔内送達
JP2021532098A (ja) 2018-07-19 2021-11-25 インペル ニューロファーマ インコーポレイテッド パーキンソン病の治療のためのレボドパおよびドーパデカルボキシラーゼ阻害剤の呼吸管路送達
AU2019418744B2 (en) 2019-01-03 2023-08-03 Impel Pharmaceuticals Inc. Nasal drug delivery device
BR112021023049A8 (pt) 2019-05-17 2022-10-18 Impel Neuropharma Inc Dispositivo de dispensação nasal de uso único

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2348264A1 (fr) 1976-04-16 1977-11-10 Montedison Spa Composition de gaz propulseurs pour aerosols
US5225183A (en) 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
US5011678A (en) 1989-02-01 1991-04-30 California Biotechnology Inc. Composition and method for administration of pharmaceutically active substances
CA2050905A1 (en) 1989-02-23 1990-08-24 George R. Felt Therapeutic aerosol formulations
HU222249B1 (hu) * 1991-03-08 2003-05-28 Amylin Pharmaceuticals Inc. Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
US5744123A (en) * 1991-12-12 1998-04-28 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
GB9202519D0 (en) 1992-02-06 1992-03-25 Glaxo Group Ltd Medicaments
WO1994016756A1 (en) * 1993-01-29 1994-08-04 Miris Medical Corporation Intrapulmonary delivery of hormones
US5743250A (en) * 1993-01-29 1998-04-28 Aradigm Corporation Insulin delivery enhanced by coached breathing
ES2218543T3 (es) * 1994-03-07 2004-11-16 Nektar Therapeutics Procedimiento y preparacion para la administracion de insulina por via pulmonar.
WO1996019198A1 (en) 1994-12-22 1996-06-27 Astra Aktiebolag Aerosol drug formulations
US6193954B1 (en) 1997-03-21 2001-02-27 Abbott Laboratories Formulations for pulmonary delivery of dopamine agonists
HUP0103369A3 (en) * 1998-08-28 2002-03-28 Lilly Co Eli Use of insulinotropic peptides

Also Published As

Publication number Publication date
EP1289573B1 (de) 2009-06-10
EP1289573A4 (de) 2003-05-14
DE60138948D1 (de) 2009-07-23
MXPA02007188A (es) 2002-12-09
CA2396785C (en) 2011-06-21
CN1235641C (zh) 2006-01-11
AU2001224716B2 (en) 2005-10-13
CA2396785A1 (en) 2001-08-02
US6540983B1 (en) 2003-04-01
EP1289573A1 (de) 2003-03-12
ES2328556T3 (es) 2009-11-16
WO2001054741A1 (en) 2001-08-02
JP2003520829A (ja) 2003-07-08
CN1427730A (zh) 2003-07-02
AU2471601A (en) 2001-08-07

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