ATE433439T1 - Anthranyl-derivate mit anti-cholecystokinin- aktivität (anti-cck-1) verfahren zu deren herstellung und deren pharmazeutische anwendung - Google Patents

Anthranyl-derivate mit anti-cholecystokinin- aktivität (anti-cck-1) verfahren zu deren herstellung und deren pharmazeutische anwendung

Info

Publication number
ATE433439T1
ATE433439T1 AT03766505T AT03766505T ATE433439T1 AT E433439 T1 ATE433439 T1 AT E433439T1 AT 03766505 T AT03766505 T AT 03766505T AT 03766505 T AT03766505 T AT 03766505T AT E433439 T1 ATE433439 T1 AT E433439T1
Authority
AT
Austria
Prior art keywords
sub
chosen
group
cck
production
Prior art date
Application number
AT03766505T
Other languages
English (en)
Inventor
Francesco Makovec
Antonio Varnavas
Lucia Lassiani
Lucio Claudio Rovati
Original Assignee
Rottapharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rottapharm Spa filed Critical Rottapharm Spa
Application granted granted Critical
Publication of ATE433439T1 publication Critical patent/ATE433439T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
AT03766505T 2002-07-26 2003-07-23 Anthranyl-derivate mit anti-cholecystokinin- aktivität (anti-cck-1) verfahren zu deren herstellung und deren pharmazeutische anwendung ATE433439T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2002TO000674A ITTO20020674A1 (it) 2002-07-26 2002-07-26 Derivati antranilici ad attivita' anticolecistochininica (anti-cck-1), procedimento per la loro preparazione e loro uso farmaceutico
PCT/IB2003/002922 WO2004013087A1 (en) 2002-07-26 2003-07-23 Anthranyl derivatives having an anticholecystokinin activity (anti-cck-1), a process for their preparation, and pharmaceutical use thereof

Publications (1)

Publication Number Publication Date
ATE433439T1 true ATE433439T1 (de) 2009-06-15

Family

ID=11459544

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03766505T ATE433439T1 (de) 2002-07-26 2003-07-23 Anthranyl-derivate mit anti-cholecystokinin- aktivität (anti-cck-1) verfahren zu deren herstellung und deren pharmazeutische anwendung

Country Status (11)

Country Link
US (1) US7294648B2 (de)
EP (1) EP1532105B1 (de)
JP (1) JP4530853B2 (de)
AT (1) ATE433439T1 (de)
AU (1) AU2003253114B8 (de)
CA (1) CA2493789C (de)
DE (1) DE60327932D1 (de)
ES (1) ES2325496T3 (de)
IT (1) ITTO20020674A1 (de)
PT (1) PT1532105E (de)
WO (1) WO2004013087A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050119666A (ko) 2003-03-28 2005-12-21 얀센 파마슈티카 엔.브이. 벤조[1,2,5]티아디아졸 화합물
MXPA06001482A (es) * 2003-08-08 2006-09-04 Johnson & Johnson Procedimiento para la preparacion de compuestos de 2-(quinoxalin-5-ilsulfonilamino)-benzamida.
KR20070057252A (ko) 2004-09-24 2007-06-04 얀센 파마슈티카 엔.브이. 설폰아미드 화합물

Also Published As

Publication number Publication date
AU2003253114B2 (en) 2009-07-16
AU2003253114A1 (en) 2004-02-23
PT1532105E (pt) 2009-06-29
ITTO20020674A1 (it) 2004-01-26
EP1532105B1 (de) 2009-06-10
JP4530853B2 (ja) 2010-08-25
JP2005533866A (ja) 2005-11-10
CA2493789A1 (en) 2004-02-12
US20060111304A1 (en) 2006-05-25
US7294648B2 (en) 2007-11-13
WO2004013087A1 (en) 2004-02-12
ITTO20020674A0 (it) 2002-07-26
EP1532105A1 (de) 2005-05-25
AU2003253114B8 (en) 2009-08-13
DE60327932D1 (de) 2009-07-23
CA2493789C (en) 2012-05-01
ES2325496T3 (es) 2009-09-07

Similar Documents

Publication Publication Date Title
EP1548008A4 (de) Verbindung mit tgf-beta-hemmender wirkung und diese enthaltende medizinische zusammensetzung
BRPI0413232B8 (pt) composto tendo atividade inibitória contra transportador dependente de sódio, composição farmacêutica compreendendo o composto, uso do composto na preparação de um medicamento e processo para a preparação do composto
NO940737D0 (no) Antidepressive midler
FR2654104B1 (fr) Nouveaux derives du 1,2-benzisoxazole, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
AR039868A1 (es) Inhibidores selectivos de la enzima kalikreina plasmatica
EA200201056A1 (ru) Новые, обладающие продолжительным действием бетамиметики, способ их получения и их применение в качестве лекарственных средств
DE602004012758D1 (de) Chinoxalinderivate als inhibitoren der neutrophilelastase und deren verwendung
FI970317A0 (fi) Antiproliferatiivisina aineina ja Garft-inhibiittoreina käyttökelpoisia yhdisteitä
ES2093332T3 (es) Nuevos derivados arilglicinamidicos, su procedimiento de preparacion y su uso para el tratamiento de la disuria.
ATE266664T1 (de) Pyridinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
DK1320526T3 (da) Farmaceutisk aktive benzsulfonamidderivater som inhibitorer af protein-junkinaser
DK1644389T3 (da) Pyrinidinforbindelser med phosphonatgrupper som antivirale nukleotidanaloger
PT790248E (pt) Derivados de 3-aza-piperidona-(tetra-hidropirimidin-2-ona) e 3-oxa-piperidona(1,3 oxazin-2-ona) sua preparacao e uso como antagonistas de taquicinina/neurocinina
DE69132689D1 (de) Biologisch aktive amine
ATE433439T1 (de) Anthranyl-derivate mit anti-cholecystokinin- aktivität (anti-cck-1) verfahren zu deren herstellung und deren pharmazeutische anwendung
EP0712398A1 (de) Benzopyrane und diese enthaltende pharmazeutische zusammenstellungen
ATE265451T1 (de) 2-aminoidan derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen
DE69204859D1 (de) Substituierte Pyridinsulfonamide oder deren Salze, Verfahren zur Herstellung und diese enthaltende Herbizide.
AR045600A1 (es) Tienoimidazoles sustituidos, procedimiento para su preparacion, su uso como un medicamento o adyuvante de diagnostico y medicamento que los comprende
EP1178031A4 (de) Verfahren zur herstellung organischer verbindungen mit mangankatalysatoren oder ähnlichen verbindungen
ATE195936T1 (de) Bis-imide derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitung
DE69409774D1 (de) Neue kardioaktive 17-Iminomethylalkenyl-5-beta-14-beta-androstan und 17-Iminoalkyl-5-beta, 14-beta-androstan Derivate, ein Verfahren zu ihrer Herstellung und pharmazeutische Präparate davon
ATE191458T1 (de) Benzol-derivate
DE69011748D1 (de) Biphenyl-Derivate, Verfahren zu deren Herstellung und deren Zwischenprodukte.
MY111111A (en) Novel (1-phenyl-1-heterocyclyl) methanol and (1-phenyl -1-heterocyclyl) methylamine drrivatives

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties