ATE433457T1 - Angiogen-wirkende trisulfat steroide und deren verwendung - Google Patents
Angiogen-wirkende trisulfat steroide und deren verwendungInfo
- Publication number
- ATE433457T1 ATE433457T1 AT03788740T AT03788740T ATE433457T1 AT E433457 T1 ATE433457 T1 AT E433457T1 AT 03788740 T AT03788740 T AT 03788740T AT 03788740 T AT03788740 T AT 03788740T AT E433457 T1 ATE433457 T1 AT E433457T1
- Authority
- AT
- Austria
- Prior art keywords
- trisulphate
- angiogenic
- steroids
- compounds
- provides
- Prior art date
Links
- 230000002491 angiogenic effect Effects 0.000 title 1
- 150000003431 steroids Chemical class 0.000 title 1
- QZLJWLSUXOQTNU-ZGETZVIFSA-N [(8s,10r,13s,17s)-17-acetyl-4-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate Chemical class C1C=C2C(O)C(OS(O)(=O)=O)CC[C@]2(C)C2[C@@H]1C1CC[C@H](C(=O)C)[C@@]1(C)CC2 QZLJWLSUXOQTNU-ZGETZVIFSA-N 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5064—Endothelial cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
- A61K38/1866—Vascular endothelial growth factor [VEGF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
- G01N33/5017—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity for testing neoplastic activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5026—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell morphology
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physiology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43586402P | 2002-12-24 | 2002-12-24 | |
| PCT/CA2003/002024 WO2004058795A1 (en) | 2002-12-24 | 2003-12-24 | Angiogenic compounds and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE433457T1 true ATE433457T1 (de) | 2009-06-15 |
Family
ID=32682287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03788740T ATE433457T1 (de) | 2002-12-24 | 2003-12-24 | Angiogen-wirkende trisulfat steroide und deren verwendung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20060014727A1 (de) |
| EP (1) | EP1575981B1 (de) |
| AT (1) | ATE433457T1 (de) |
| AU (1) | AU2003292939A1 (de) |
| CA (1) | CA2508913A1 (de) |
| DE (1) | DE60327946D1 (de) |
| WO (1) | WO2004058795A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8352400B2 (en) | 1991-12-23 | 2013-01-08 | Hoffberg Steven M | Adaptive pattern recognition based controller apparatus and method and human-factored interface therefore |
| US7904187B2 (en) | 1999-02-01 | 2011-03-08 | Hoffberg Steven M | Internet appliance system and method |
| WO2010024930A2 (en) | 2008-08-28 | 2010-03-04 | President And Fellows Of Harvard College | Cortistatin analogues and syntheses therof |
| EP2421882A4 (de) * | 2009-04-22 | 2013-05-08 | Harvard College | Angiogenesehemmer |
| KR102057812B1 (ko) | 2012-04-20 | 2019-12-19 | 오에이치알 파마서티컬, 인코포레이티드 | Ptp1b 연관 질병의 치료용 아미노스테로이드 |
| ES2709480T3 (es) | 2013-12-24 | 2019-04-16 | Harvard College | Análogos de cortistatina y síntesis y usos de los mismos |
| EP3294298A4 (de) | 2015-05-08 | 2018-10-17 | President and Fellows of Harvard College | Cortistatin-analoga, synthese und verwendungen |
| WO2017004411A1 (en) | 2015-07-01 | 2017-01-05 | President And Fellows Of Harvard College | Cortistatin analogues and syntheses and uses thereof |
| CN116836215B (zh) * | 2023-07-11 | 2025-10-10 | 中国药科大学 | 一种天然产物Sokotrasterol sulfate的合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE794362A (fr) * | 1972-01-22 | 1973-07-23 | Merck Patent Gmbh | Sulfates hydrosolubles de sterine |
| US5198432A (en) * | 1988-01-29 | 1993-03-30 | Center For Innovative Technology | Method of preventing chlorohydrocarbon toxicity using sterol derivatives |
| US5079239A (en) * | 1990-02-16 | 1992-01-07 | Harbor Branch Oceanographic Institution, Inc. | Sterol disulfates and methods of use |
| US5866561A (en) * | 1997-08-21 | 1999-02-02 | Scimed Life Systems, Inc. | Local delivery of estrogen for angiogenesis |
-
2003
- 2003-12-24 WO PCT/CA2003/002024 patent/WO2004058795A1/en not_active Ceased
- 2003-12-24 DE DE60327946T patent/DE60327946D1/de not_active Expired - Fee Related
- 2003-12-24 EP EP03788740A patent/EP1575981B1/de not_active Expired - Lifetime
- 2003-12-24 AU AU2003292939A patent/AU2003292939A1/en not_active Abandoned
- 2003-12-24 CA CA002508913A patent/CA2508913A1/en not_active Abandoned
- 2003-12-24 AT AT03788740T patent/ATE433457T1/de not_active IP Right Cessation
-
2005
- 2005-06-20 US US11/158,291 patent/US20060014727A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60327946D1 (de) | 2009-07-23 |
| US20060014727A1 (en) | 2006-01-19 |
| EP1575981B1 (de) | 2009-06-10 |
| CA2508913A1 (en) | 2004-07-15 |
| WO2004058795A1 (en) | 2004-07-15 |
| AU2003292939A1 (en) | 2004-07-22 |
| EP1575981A1 (de) | 2005-09-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1116779T1 (el) | Αμιδο ενωσεις και η χρηση τους ως φαρμακευτικες ουσιες | |
| CY1117124T1 (el) | ΑΝΘΡΩΠΟΠΟΙΗΜΕΝΟΙ ANTΑΓΩΝΙΣΤΕΣ ΑΝΤΙ-β7 ΚΑΙ ΧΡΗΣΕΙΣ ΑΥΤΩΝ | |
| DE60137307D1 (de) | Substituierte sapogenine und ihre verwendung | |
| CY1110026T1 (el) | Ενωσεις πιπεραζινης βενζισοξαζολης και μεθοδοι χρησης εξ αυτων | |
| ATE365165T1 (de) | Diaminopyrimidine und deren verwendung als angiogenesehemmer | |
| DE60332475D1 (de) | Zusammensetzungen verwendbar für die hemmung von rock und anderen kinasen | |
| AP2004003192A0 (en) | Combination of azelastine and steroids. | |
| ATE424211T1 (de) | Therapeutische verwendung von sapogeninen | |
| DE60142921D1 (de) | Azaphenanthridone-derivate und deren verwendung als parp-inhibitoren | |
| DK1778236T3 (da) | Modificerede pyrimidin-glucocorticoid-receptor-modulatorer | |
| PT1421099E (pt) | Esteres de 17-alfa, 21-di-hidroxipregneno como agentes anti-androgenicos | |
| TR200301613T2 (tr) | Sapogenin türevleri, bunların sentezi ve kullanımı, bunların kullanım metotları. | |
| ATE325789T1 (de) | Aminocyclohexylether-verbindungen und deren verwendung | |
| DE60027913D1 (de) | 5-beta-sapogenin und pseudosapogeninderivate und ihre verwendung zur behandlung von demenz | |
| DE60321041D1 (de) | Antikörper gegen krebsantigen tmeff2 und seine anwendungen | |
| DE60327946D1 (de) | Angiogen-wirkende trisulfat steroide und deren verwendung | |
| ATE338550T1 (de) | Mikronisierter zolpidem hemitartrat | |
| DE60304788D1 (de) | Granulatförmige photokatalytische Mischung für Mörtel oder Beton und ihre Verwendung | |
| DE50208918D1 (de) | 6-aminomorphinanderivate, herstellungsverfahren dafür und deren verwendung | |
| CY1105607T1 (el) | Η χρηση ενος η1 ανταγωνιστη και ριμεξαολης ως ενα ασφαλες στεροειδες για την θεραπεια ρινιτιδας | |
| PL372460A1 (en) | C-17 spirolactonization and 6,7 oxidation of steroids | |
| NO20033321D0 (no) | Androgeniske 7-substituerte 11-halogensteroider | |
| CY1106754T1 (el) | Σκευασματα τιμπολονης | |
| DE60323513D1 (de) | Oberflächenmodifizierte plexifilamentarstrukturen und zusammensetzungen dafür | |
| ATE321760T1 (de) | N-aryl-2-oxazolidinone und deren derivate |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |