ATE321760T1 - N-aryl-2-oxazolidinone und deren derivate - Google Patents
N-aryl-2-oxazolidinone und deren derivateInfo
- Publication number
- ATE321760T1 ATE321760T1 AT03784775T AT03784775T ATE321760T1 AT E321760 T1 ATE321760 T1 AT E321760T1 AT 03784775 T AT03784775 T AT 03784775T AT 03784775 T AT03784775 T AT 03784775T AT E321760 T1 ATE321760 T1 AT E321760T1
- Authority
- AT
- Austria
- Prior art keywords
- oxazolidinone
- aryl
- derivatives
- formula
- present
- Prior art date
Links
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Structure Of Belt Conveyors (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40278302P | 2002-08-12 | 2002-08-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE321760T1 true ATE321760T1 (de) | 2006-04-15 |
Family
ID=31715900
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03784775T ATE321760T1 (de) | 2002-08-12 | 2003-08-01 | N-aryl-2-oxazolidinone und deren derivate |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7094900B2 (de) |
| EP (1) | EP1539745B1 (de) |
| JP (1) | JP2005537301A (de) |
| AT (1) | ATE321760T1 (de) |
| AU (1) | AU2003259159A1 (de) |
| BR (1) | BR0313400A (de) |
| CA (1) | CA2491287A1 (de) |
| DE (1) | DE60304360T2 (de) |
| ES (1) | ES2258234T3 (de) |
| MX (1) | MXPA05001558A (de) |
| WO (1) | WO2004014897A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1658286A1 (de) * | 2003-08-22 | 2006-05-24 | Pharmacia & Upjohn Company LLC | N-aryl-2-cyanooxazolidinone und deren derivative |
| US7186844B2 (en) * | 2004-01-13 | 2007-03-06 | Mitsubishi Gas Chemical Co., Inc. | Method for producing cyclic carbamate ester |
| WO2005113520A1 (en) * | 2004-05-20 | 2005-12-01 | Pharmacia & Upjohn Company Llc | Substituted 2,3,5-trifluorphenyl oxazolidinones for use as antibacterial agents |
| WO2016061772A1 (en) | 2014-10-22 | 2016-04-28 | Merck Sharp & Dohme Corp. | Nargenicin compounds and uses thereof as antibacterial agents |
| WO2017066964A1 (en) | 2015-10-22 | 2017-04-27 | Merck Sharp & Dohme Corp. | Oxazolidinone compounds and methods of use thereof as antibacterial agents |
| WO2021184339A1 (en) | 2020-03-20 | 2021-09-23 | Merck Sharp & Dohme Corp. | Oxazolidinone compound and methods of use thereof as an antibacterial agent |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4705799A (en) | 1983-06-07 | 1987-11-10 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents |
| US5043443A (en) | 1988-07-29 | 1991-08-27 | Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives |
| US5164510A (en) | 1988-09-15 | 1992-11-17 | The Upjohn Company | 5'Indolinyl-5β-amidomethyloxazolidin-2-ones |
| US5225565A (en) | 1988-09-15 | 1993-07-06 | The Upjohn Company | Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones |
| US5182403A (en) | 1988-09-15 | 1993-01-26 | The Upjohn Company | Substituted 3(5'indazolyl) oxazolidin-2-ones |
| US5231188A (en) | 1989-11-17 | 1993-07-27 | The Upjohn Company | Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents |
| ATE146783T1 (de) | 1991-11-01 | 1997-01-15 | Upjohn Co | Substituierte aryl- und heteroaryl- phenyloxazolidinone |
| SK283420B6 (sk) | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
| KR950702417A (ko) | 1992-07-08 | 1995-07-29 | 로렌스 티. 웰츠 | 마이코박테륨 투베르쿨로시스에 대해 유용한 5′-인돌리닐 옥사졸리디논(5′-indolinyl oxazolidinones useful against mycobacterium tuberculosis) |
| PL175782B1 (pl) | 1992-12-08 | 1999-02-26 | Upjohn Co | Nowe podstawione troponem pochodne fenylooksazolidynonowe |
| MY115155A (en) | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
| US5688792A (en) | 1994-08-16 | 1997-11-18 | Pharmacia & Upjohn Company | Substituted oxazine and thiazine oxazolidinone antimicrobials |
| WO1995014684A1 (en) | 1993-11-22 | 1995-06-01 | The Upjohn Company | Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones |
| JPH0873455A (ja) | 1994-03-15 | 1996-03-19 | Upjohn Co:The | オキサゾリジノン誘導体及びこれを有効成分とする医薬組成物 |
| DE4425613A1 (de) | 1994-07-20 | 1996-01-25 | Bayer Ag | 5-gliedrige Heteroaryl-oxazolidinone |
| DE4425612A1 (de) | 1994-07-20 | 1996-04-04 | Bayer Ag | 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone |
| DE4425609A1 (de) | 1994-07-20 | 1996-01-25 | Bayer Ag | Benzofuranyl- und Benzothienyloxazolidinone |
| DE19514313A1 (de) | 1994-08-03 | 1996-02-08 | Bayer Ag | Benzoxazolyl- und Benzothiazolyloxazolidinone |
| SK282869B6 (sk) | 1994-10-26 | 2003-01-09 | Pharmacia + Upjohn Company | Antimikrobiálne fenyloxazolidinóny |
| NZ295528A (en) | 1994-11-15 | 1999-03-29 | Upjohn Co | Bicyclic oxazine and thiazine oxazolidinone antibacterials |
| CA2208603A1 (en) | 1995-02-03 | 1996-08-08 | The Upjohn Company | Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials |
| HRP960159A2 (en) | 1995-04-21 | 1997-08-31 | Bayer Ag | Benzocyclopentane oxazolidinones containing heteroatoms |
| ES2162047T3 (es) | 1995-05-11 | 2001-12-16 | Upjohn Co | Oxazolidinonas con resto diazinilo y carbazinilo espirociclico y biciclico. |
| CN1072222C (zh) | 1995-09-01 | 2001-10-03 | 法玛西雅厄普约翰公司 | 以c－c键连接于4－8元杂环环的苯基噁唑烷酮 |
| EP1019385B1 (de) | 1995-09-15 | 2004-01-14 | PHARMACIA & UPJOHN COMPANY | Aminoaryl oxazolidinone n-oxide |
| ZA968661B (en) | 1995-11-17 | 1998-04-14 | Upjohn Co | Oxazolidinone antibacterial agent with tricyclic substituents. |
| DE19601265A1 (de) | 1996-01-16 | 1997-07-17 | Bayer Ag | 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone |
| DE19601264A1 (de) | 1996-01-16 | 1997-07-17 | Bayer Ag | Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone |
| DE19601627A1 (de) | 1996-01-18 | 1997-07-24 | Bayer Ag | Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone |
| GB9601666D0 (en) | 1996-01-27 | 1996-03-27 | Zeneca Ltd | Chemical compounds |
| DE19604223A1 (de) | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue substituierte Oxazolidinone |
| GB9702213D0 (en) | 1996-02-24 | 1997-03-26 | Zeneca Ltd | Chemical compounds |
| MY116093A (en) | 1996-02-26 | 2003-11-28 | Upjohn Co | Azolyl piperazinyl phenyl oxazolidinone antimicrobials |
| GB9609919D0 (en) | 1996-05-11 | 1996-07-17 | Zeneca Ltd | Chemical compounds |
| CA2288750A1 (en) | 1997-05-30 | 1998-12-03 | Pharmacia & Upjohn Company | Oxazolidinone antibacterial agents having a thiocarbonyl functionality |
| DE19730847A1 (de) | 1997-07-18 | 1999-01-28 | Bayer Ag | Tricyclisch substituierte Oxazolidinone |
| GB9717804D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
| CA2303959A1 (en) * | 1997-11-12 | 1999-05-20 | Pharmacia & Upjohn Company | Oxazolidinone derivatives and pharmaceutical compositions |
| US6083967A (en) | 1997-12-05 | 2000-07-04 | Pharmacia & Upjohn Company | S-oxide and S,S-dioxide tetrahydrothiopyran phenyloxazolidinones |
| DE19802235A1 (de) | 1998-01-22 | 1999-07-29 | Bayer Ag | Mit tricyclischen Indolen substituierte Oxazolidinone |
| DE19802239A1 (de) | 1998-01-22 | 1999-07-29 | Bayer Ag | Neue mit Bicyclen substituierte Oxazolidinone |
| US6239152B1 (en) | 1998-01-23 | 2001-05-29 | Pharmacia & Upjohn Company | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
| DE19805117A1 (de) | 1998-02-09 | 1999-08-12 | Bayer Ag | Neue Oxazolidinone mit azolhaltigen Tricyclen |
| GB9821938D0 (en) | 1998-10-09 | 1998-12-02 | Zeneca Ltd | Chemical compounds |
| GB9928499D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical processes and intermediates |
| GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| JP2003535860A (ja) | 2000-06-05 | 2003-12-02 | ドン・ア・ファーム・カンパニー・リミテッド | 新規なオキサゾリジノン誘導体及びその製造方法 |
-
2003
- 2003-08-01 DE DE60304360T patent/DE60304360T2/de not_active Expired - Fee Related
- 2003-08-01 MX MXPA05001558A patent/MXPA05001558A/es unknown
- 2003-08-01 EP EP03784775A patent/EP1539745B1/de not_active Expired - Lifetime
- 2003-08-01 CA CA002491287A patent/CA2491287A1/en not_active Abandoned
- 2003-08-01 JP JP2004527615A patent/JP2005537301A/ja active Pending
- 2003-08-01 AU AU2003259159A patent/AU2003259159A1/en not_active Abandoned
- 2003-08-01 BR BR0313400-8A patent/BR0313400A/pt not_active IP Right Cessation
- 2003-08-01 ES ES03784775T patent/ES2258234T3/es not_active Expired - Lifetime
- 2003-08-01 AT AT03784775T patent/ATE321760T1/de not_active IP Right Cessation
- 2003-08-01 WO PCT/US2003/022486 patent/WO2004014897A1/en not_active Ceased
- 2003-08-01 US US10/632,742 patent/US7094900B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005537301A (ja) | 2005-12-08 |
| BR0313400A (pt) | 2005-07-12 |
| EP1539745A1 (de) | 2005-06-15 |
| MXPA05001558A (es) | 2005-09-08 |
| US7094900B2 (en) | 2006-08-22 |
| CA2491287A1 (en) | 2004-02-19 |
| ES2258234T3 (es) | 2006-08-16 |
| DE60304360D1 (de) | 2006-05-18 |
| DE60304360T2 (de) | 2006-11-16 |
| EP1539745B1 (de) | 2006-03-29 |
| AU2003259159A1 (en) | 2004-02-25 |
| WO2004014897A1 (en) | 2004-02-19 |
| US20040072873A1 (en) | 2004-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |