ATE434625T1 - Verfahren zur schmerzbehandlung durch verabreichung eines antagonistischen antikörpers gegen den nervenwachstumfaktor und eines opioid- analgetikums sowie diese enthaltende zusammensetzungen - Google Patents
Verfahren zur schmerzbehandlung durch verabreichung eines antagonistischen antikörpers gegen den nervenwachstumfaktor und eines opioid- analgetikums sowie diese enthaltende zusammensetzungenInfo
- Publication number
- ATE434625T1 ATE434625T1 AT03816571T AT03816571T ATE434625T1 AT E434625 T1 ATE434625 T1 AT E434625T1 AT 03816571 T AT03816571 T AT 03816571T AT 03816571 T AT03816571 T AT 03816571T AT E434625 T1 ATE434625 T1 AT E434625T1
- Authority
- AT
- Austria
- Prior art keywords
- growth factor
- antibody against
- nerve growth
- opioid analgesic
- antagonist antibody
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Emergency Medicine (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41734702P | 2002-10-08 | 2002-10-08 | |
| PCT/US2003/032113 WO2004096122A2 (en) | 2002-10-08 | 2003-10-08 | Use of ngf antagonists and opioids for treating pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE434625T1 true ATE434625T1 (de) | 2009-07-15 |
Family
ID=33415832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03816571T ATE434625T1 (de) | 2002-10-08 | 2003-10-08 | Verfahren zur schmerzbehandlung durch verabreichung eines antagonistischen antikörpers gegen den nervenwachstumfaktor und eines opioid- analgetikums sowie diese enthaltende zusammensetzungen |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20040131615A1 (de) |
| EP (2) | EP2100902B1 (de) |
| JP (1) | JP2006517524A (de) |
| KR (1) | KR20050067174A (de) |
| CN (1) | CN1878794B (de) |
| AT (1) | ATE434625T1 (de) |
| AU (1) | AU2003304060A1 (de) |
| BR (1) | BR0315167A (de) |
| CA (1) | CA2501694A1 (de) |
| DE (1) | DE60328128D1 (de) |
| ES (2) | ES2326881T3 (de) |
| MX (1) | MXPA05003501A (de) |
| NO (1) | NO20052221L (de) |
| PL (1) | PL379989A1 (de) |
| RU (1) | RU2005113996A (de) |
| UA (1) | UA80447C2 (de) |
| WO (1) | WO2004096122A2 (de) |
| ZA (1) | ZA200502611B (de) |
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| CA2500901A1 (en) * | 2002-10-04 | 2004-04-22 | Rinat Neuroscience Corp. | Methods for treating cardiac arrhythmia and preventing death due to cardiac arrhythmia using ngf antagonists |
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| US7569364B2 (en) * | 2002-12-24 | 2009-08-04 | Pfizer Inc. | Anti-NGF antibodies and methods using same |
| AU2011201157C1 (en) * | 2002-12-24 | 2017-09-07 | Rinat Neuroscience Corp. | Anti-NGF antibodies and methods using same |
| EP2270048B1 (de) | 2002-12-24 | 2015-11-11 | Rinat Neuroscience Corp. | Anti-NGF Antikörper und Verfahren zu ihrer Verwendung |
| US9498530B2 (en) | 2002-12-24 | 2016-11-22 | Rinat Neuroscience Corp. | Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same |
| KR20050111598A (ko) | 2003-02-19 | 2005-11-25 | 리나트 뉴로사이언스 코퍼레이션 | 신경 성장 인자 길항제 및 nsaid를 투여함으로써통증을 치료하는 방법 및 그것을 함유하는 조성물 |
| ITRM20030601A1 (it) | 2003-12-24 | 2005-06-25 | Lay Line Genomics Spa | Metodo per l'umanizzazione di anticorpi e anticorpi umanizzati con esso ottenuti. |
| AU2005243247B2 (en) * | 2004-04-07 | 2012-03-01 | Regents Of The University Of Minnesota | Methods for treating bone cancer pain by administering a nerve growth factor antagonist |
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| ITRM20050332A1 (it) * | 2005-06-24 | 2006-12-25 | Lay Line Genomics Spa | Uso di molecole in grado di bloccare l'attivita' di trka per potenziare gli effetti di analgesici oppiacei sul dolore. |
| JP2009508970A (ja) | 2005-09-21 | 2009-03-05 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 疼痛の局所造影および治療のためのシステム、組成物並びに方法 |
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| MY161564A (en) | 2007-08-10 | 2017-04-28 | Regeneron Pharma | High affinity human antibodies to human nerve growth factor |
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| AU2009211340B2 (en) | 2008-02-04 | 2013-09-12 | Lay Line Genomics S.P.A. | Anti-TrkA antibodies and derivatives thereof |
| US20090286832A1 (en) * | 2008-05-15 | 2009-11-19 | Kiichiro Nabeta | Narcotic emulsion formulations for treatment of surgical pain |
| KR101694559B1 (ko) | 2008-09-24 | 2017-01-09 | 가부시키가이샤 리보믹 | Ngf에 대한 압타머 및 이의 용도 |
| CN106336400A (zh) | 2008-12-08 | 2017-01-18 | 萌蒂制药国际有限公司 | 酪氨酸激酶蛋白受体拮抗剂 |
| KR20120088550A (ko) | 2009-05-04 | 2012-08-08 | 애보트 리서치 비.브이. | 증진된 생체내 안정성을 갖는 신경 성장 인자(ngf)에 대한 항체 |
| TWI500425B (zh) | 2010-03-24 | 2015-09-21 | Ribomic Inc | 對ngf之適體及其用途 |
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| JP6105838B2 (ja) * | 2010-08-24 | 2017-03-29 | 国立大学法人 岡山大学 | 疼痛の治療剤 |
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| US9884909B2 (en) | 2010-12-01 | 2018-02-06 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
| US9539324B2 (en) | 2010-12-01 | 2017-01-10 | Alderbio Holdings, Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
| US9067988B2 (en) | 2010-12-01 | 2015-06-30 | Alderbio Holdings Llc | Methods of preventing or treating pain using anti-NGF antibodies |
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| US9078878B2 (en) | 2010-12-01 | 2015-07-14 | Alderbio Holdings Llc | Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75 |
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| RS66303B1 (sr) | 2011-05-20 | 2025-01-31 | H Lundbeck As | Upotreba anti-cgrp antitela i fragmenata antitela za sprečavanje ili inhibiranje fotofobije ili odbojnosti prema svetlu kod subjekata kojima je to potrebno, naročito kod subjekata koji pate od migrene |
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-
2003
- 2003-08-10 UA UAA200504332A patent/UA80447C2/uk unknown
- 2003-10-08 CA CA002501694A patent/CA2501694A1/en not_active Abandoned
- 2003-10-08 ES ES03816571T patent/ES2326881T3/es not_active Expired - Lifetime
- 2003-10-08 PL PL379989A patent/PL379989A1/pl not_active Application Discontinuation
- 2003-10-08 US US10/682,332 patent/US20040131615A1/en not_active Abandoned
- 2003-10-08 AU AU2003304060A patent/AU2003304060A1/en not_active Abandoned
- 2003-10-08 WO PCT/US2003/032113 patent/WO2004096122A2/en not_active Ceased
- 2003-10-08 DE DE60328128T patent/DE60328128D1/de not_active Expired - Lifetime
- 2003-10-08 ES ES09163527T patent/ES2767744T3/es not_active Expired - Lifetime
- 2003-10-08 MX MXPA05003501A patent/MXPA05003501A/es not_active Application Discontinuation
- 2003-10-08 EP EP09163527.6A patent/EP2100902B1/de not_active Revoked
- 2003-10-08 JP JP2004571457A patent/JP2006517524A/ja not_active Withdrawn
- 2003-10-08 KR KR1020057006105A patent/KR20050067174A/ko not_active Ceased
- 2003-10-08 RU RU2005113996/14A patent/RU2005113996A/ru not_active Application Discontinuation
- 2003-10-08 CN CN2003801053379A patent/CN1878794B/zh not_active Expired - Lifetime
- 2003-10-08 BR BR0315167-0A patent/BR0315167A/pt not_active IP Right Cessation
- 2003-10-08 AT AT03816571T patent/ATE434625T1/de not_active IP Right Cessation
- 2003-10-08 EP EP03816571A patent/EP1575522B1/de not_active Revoked
-
2005
- 2005-03-31 ZA ZA200502611A patent/ZA200502611B/en unknown
- 2005-05-06 NO NO20052221A patent/NO20052221L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20052221D0 (no) | 2005-05-06 |
| US20040131615A1 (en) | 2004-07-08 |
| WO2004096122A3 (en) | 2006-06-01 |
| DE60328128D1 (de) | 2009-08-06 |
| UA80447C2 (en) | 2007-09-25 |
| EP2100902B1 (de) | 2019-12-18 |
| EP1575522A4 (de) | 2007-05-30 |
| CA2501694A1 (en) | 2004-11-11 |
| CN1878794A (zh) | 2006-12-13 |
| PL379989A1 (pl) | 2006-11-27 |
| EP1575522B1 (de) | 2009-06-24 |
| NO20052221L (no) | 2005-07-07 |
| ZA200502611B (en) | 2006-06-28 |
| CN1878794B (zh) | 2011-11-30 |
| WO2004096122A2 (en) | 2004-11-11 |
| JP2006517524A (ja) | 2006-07-27 |
| BR0315167A (pt) | 2005-08-23 |
| ES2767744T3 (es) | 2020-06-18 |
| KR20050067174A (ko) | 2005-06-30 |
| EP2100902A1 (de) | 2009-09-16 |
| ES2326881T3 (es) | 2009-10-21 |
| RU2005113996A (ru) | 2005-10-27 |
| MXPA05003501A (es) | 2005-10-19 |
| AU2003304060A1 (en) | 2004-11-23 |
| EP1575522A2 (de) | 2005-09-21 |
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