ATE435232T1 - Nukleotid- und proteinsequenzen von nogo-genen und darauf beruhende methoden - Google Patents

Nukleotid- und proteinsequenzen von nogo-genen und darauf beruhende methoden

Info

Publication number
ATE435232T1
ATE435232T1 AT99972673T AT99972673T ATE435232T1 AT E435232 T1 ATE435232 T1 AT E435232T1 AT 99972673 T AT99972673 T AT 99972673T AT 99972673 T AT99972673 T AT 99972673T AT E435232 T1 ATE435232 T1 AT E435232T1
Authority
AT
Austria
Prior art keywords
nucleotide
protein sequences
methods based
nogo
nogo genes
Prior art date
Application number
AT99972673T
Other languages
English (en)
Inventor
Martin Ernst Schwab
Maio Su Chen
Original Assignee
Univ Zuerich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22316666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE435232(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Zuerich filed Critical Univ Zuerich
Application granted granted Critical
Publication of ATE435232T1 publication Critical patent/ATE435232T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT99972673T 1998-11-06 1999-11-05 Nukleotid- und proteinsequenzen von nogo-genen und darauf beruhende methoden ATE435232T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10744698P 1998-11-06 1998-11-06
PCT/US1999/026160 WO2000031235A2 (en) 1998-11-06 1999-11-05 Nucleotide and protein sequences of nogo genes and methods based thereon

Publications (1)

Publication Number Publication Date
ATE435232T1 true ATE435232T1 (de) 2009-07-15

Family

ID=22316666

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99972673T ATE435232T1 (de) 1998-11-06 1999-11-05 Nukleotid- und proteinsequenzen von nogo-genen und darauf beruhende methoden

Country Status (26)

Country Link
US (4) US7781188B1 (de)
EP (3) EP1124846B1 (de)
JP (2) JP2003531566A (de)
KR (1) KR100728405B1 (de)
CN (3) CN101684155A (de)
AT (1) ATE435232T1 (de)
AU (1) AU774367C (de)
BR (1) BR9915137A (de)
CA (1) CA2350395C (de)
CY (1) CY1110679T1 (de)
CZ (1) CZ304224B6 (de)
DE (1) DE69941059D1 (de)
DK (1) DK1124846T3 (de)
ES (2) ES2529196T3 (de)
HU (1) HUP0301829A3 (de)
IL (3) IL142989A0 (de)
MX (1) MXPA01004598A (de)
NO (1) NO332460B1 (de)
NZ (1) NZ511683A (de)
PL (1) PL204293B1 (de)
PT (1) PT1124846E (de)
RU (3) RU2304585C2 (de)
SK (1) SK287323B6 (de)
TR (1) TR200700740T2 (de)
WO (1) WO2000031235A2 (de)
ZA (1) ZA200103714B (de)

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EP2264174A3 (de) * 1998-07-22 2012-03-07 SmithKline Beecham Limited Protein, das mit einem Neuroendokrinspezifischen Protein änhelt, und dafür kodierende cDNS
KR100728405B1 (ko) 1998-11-06 2007-06-13 더 유니버시티 오브 취리히 Ｎｏｇｏ 유전자의 뉴클레오티드와 단백질 서열 및 이들에기초한 방법
US7186530B1 (en) 2000-04-07 2007-03-06 Chiron Corporation Protein associated with cell stress response
AU4216200A (en) * 1999-04-08 2000-10-23 Chiron Corporation Novel protein associated with cell stress response
ES2341842T3 (es) * 2000-01-12 2010-06-29 Yale University Bloqueo del crecimiento axonal mediado por el receptor de nogo.
US7119165B2 (en) * 2000-01-12 2006-10-10 Yale University Nogo receptor-mediated blockade of axonal growth
US7049395B2 (en) 2000-05-02 2006-05-23 Yale University Anti-inflammatory compounds and uses thereof
ES2341608T3 (es) 2000-10-06 2010-06-23 Yale University Homologos del receptor de nogo.
GB0101313D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
GB0101312D0 (en) 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
TWI323265B (en) 2002-08-06 2010-04-11 Glaxo Group Ltd Antibodies
GB0228832D0 (en) 2002-12-10 2003-01-15 Novartis Ag Organic compound
WO2004039836A1 (en) * 2002-10-31 2004-05-13 Pieris Proteolab Ag Soluble truncated polypeptides of the nogo-a protein
GB0306309D0 (en) 2003-03-19 2003-04-23 Glaxo Group Ltd Method of treatment
DK1711530T3 (da) * 2003-12-22 2009-12-14 Glaxo Group Ltd Nogo-A-neutraliserende immunoglobuliner til behandling af neurologiske sygdomme
EP1776136B1 (de) 2004-06-24 2012-10-03 Biogen Idec MA Inc. Behandlung von entmyelinisierenden erkrankungen
KR100659820B1 (ko) 2004-11-17 2006-12-19 삼성에스디아이 주식회사 리튬 이온 이차 전지
US20090137484A1 (en) * 2004-12-01 2009-05-28 National University Of Singapore Neuronal Network-Interacting Peptide
EP1904091A4 (de) 2005-07-07 2009-12-23 Univ Yale Zusammensetzungen und verfahren zur unterdrückung der axonalen wachstumshemmung
AU2006269458B2 (en) 2005-07-08 2012-11-08 Biogen Ma Inc. Sp35 antibodies and uses thereof
WO2007014382A1 (en) * 2005-07-28 2007-02-01 Wyeth Compositions and methods of mutant nogo-66 domain proteins
BRPI0618609A2 (pt) 2005-11-16 2011-09-06 Novartis Ag biomarcadores para tratamento com anticorpo anti-nogo-a em danos à medula espinhal
GB0525662D0 (en) 2005-12-16 2006-01-25 Glaxo Group Ltd Immunoglobulins
WO2007137303A2 (en) * 2006-05-24 2007-11-29 Myelin Repair Foundation, Inc. Permeability of blood-brain barrier
CN101015683B (zh) * 2007-01-18 2010-07-21 复旦大学 人rtn4b蛋白在制备创伤愈合药物中的应用
JP5698534B2 (ja) * 2007-11-02 2015-04-08 ノバルティス アーゲー 改良されたｎｏｇｏ−ａ結合分子およびその医薬的使用
NZ584684A (en) * 2007-11-22 2012-10-26 Symphogen As A method for characterization of a recombinant polyclonal protein
DK2982695T3 (da) 2008-07-09 2019-05-13 Biogen Ma Inc Sammensætninger, der omfatter antistoffer mod lingo eller fragmenter deraf
AU2010256880B2 (en) * 2009-06-02 2015-01-22 Opko Health, Inc. Identification of small molecules recognized by antibodies in subjects with neurodegenerative diseases
US8828390B2 (en) 2010-07-09 2014-09-09 Universitat Zurich Uses of NOGO-A inhibitors and related methods
RU2478646C1 (ru) * 2011-11-28 2013-04-10 Федеральное государственное бюджетное учреждение науки Институт молекулярной биологии им.В.А.Энгельгардта Российской академии наук (ИМБ РАН) Способ получения высокоаффинных поликлональных антител
NZ702178A (en) 2012-05-14 2017-01-27 Biogen Ma Inc Lingo-2 antagonists for treatment of conditions involving motor neurons
CA2920303C (en) 2013-08-08 2017-08-29 Global Bio Therapeutics, Inc. Injection device for minimally invasive procedures and uses thereof
KR101685109B1 (ko) * 2014-12-22 2016-12-09 경북대학교 산학협력단 근육 분화, 재생, 또는 질환 상태와 관련된 노고-에이의 용도
WO2016112270A1 (en) 2015-01-08 2016-07-14 Biogen Ma Inc. Lingo-1 antagonists and uses for treatment of demyelinating disorders
EP3250220B1 (de) * 2015-01-27 2020-03-11 Universität Zürich Agonisten des nogo-a s1pr-pfads zur behandlung von glioblastomen

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US5091313A (en) * 1988-08-05 1992-02-25 Tanox Biosystems, Inc. Antigenic epitopes of IgE present on B cell but not basophil surface
EP0413763B1 (de) 1988-06-13 1996-11-06 American Biogenetic Sciences, Inc. Verfahren zur herstellung monoklonaler antikörper mit hilfe eines keimfreien tieres
AU652537B2 (en) * 1988-11-04 1994-09-01 Erziehungsdirektion Of The Canton Zurich Neurite growth regulatory factors
CA1341050C (en) * 1988-11-04 2000-07-11 Martin E. Schwab Neurite growth regulatory factors
US5250414A (en) 1988-11-04 1993-10-05 Erziehungsdirektion Of The Canton Zurich Diagnostic methods using neurite growth regulatory factors
AU2152092A (en) * 1991-06-24 1993-01-25 Erziehungsdirektion Of The Canton Zurich Neurite growth regulatory factors
US5858708A (en) * 1996-08-12 1999-01-12 Bandman; Olga Polynucleotides encoding two novel human neuroendocrine-specific proteins
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WO1999033979A2 (en) * 1997-12-30 1999-07-08 Chiron Corporation Bone marrow secreted proteins and polynucleotides
US6607879B1 (en) * 1998-02-09 2003-08-19 Incyte Corporation Compositions for the detection of blood cell and immunological response gene expression
US20020072493A1 (en) * 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
EP2264174A3 (de) * 1998-07-22 2012-03-07 SmithKline Beecham Limited Protein, das mit einem Neuroendokrinspezifischen Protein änhelt, und dafür kodierende cDNS
AU5784799A (en) * 1998-08-24 2000-03-14 Alphagene, Inc. Secreted proteins and polynucleotides encoding them
KR100728405B1 (ko) 1998-11-06 2007-06-13 더 유니버시티 오브 취리히 Ｎｏｇｏ 유전자의 뉴클레오티드와 단백질 서열 및 이들에기초한 방법
WO2001036631A1 (en) * 1999-11-15 2001-05-25 Smithkline Beecham P.L.C. Human nogo-c polynucleotide and polypeptide and their uses
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Also Published As

Publication number Publication date
JP2003531566A (ja) 2003-10-28
PT1124846E (pt) 2009-10-08
NO20012223D0 (no) 2001-05-04
ES2329635T3 (es) 2009-11-27
US7425334B2 (en) 2008-09-16
MXPA01004598A (es) 2002-04-24
SK287323B6 (sk) 2010-07-07
WO2000031235A3 (en) 2000-11-09
KR20020003353A (ko) 2002-01-12
CA2350395C (en) 2014-07-08
HK1038027A1 (en) 2002-03-01
NZ511683A (en) 2004-06-25
RU2001115705A (ru) 2004-03-10
IL198027A (en) 2011-10-31
NO332460B1 (no) 2012-09-24
IL142989A0 (en) 2002-04-21
AU774367B2 (en) 2004-06-24
CN101684155A (zh) 2010-03-31
ES2529196T3 (es) 2015-02-17
CN1354755B (zh) 2010-06-02
US20110086034A1 (en) 2011-04-14
RU2358982C2 (ru) 2009-06-20
CZ20011608A3 (cs) 2001-10-17
HUP0301829A3 (en) 2009-03-30
EP2093294B1 (de) 2014-10-29
WO2000031235A2 (en) 2000-06-02
CA2350395A1 (en) 2000-06-02
RU2304585C2 (ru) 2007-08-20
IL142989A (en) 2010-12-30
RU2004103555A (ru) 2005-07-20
CN1721444A (zh) 2006-01-18
US7781188B1 (en) 2010-08-24
CN1354755A (zh) 2002-06-19
PL362990A1 (en) 2004-11-15
CZ304224B6 (cs) 2014-01-15
DK1124846T3 (da) 2009-10-26
NO20012223L (no) 2001-07-02
ZA200103714B (en) 2004-06-25
RU2009103533A (ru) 2010-11-10
AU774367C (en) 2005-04-21
SK6222001A3 (en) 2001-12-03
EP1124846A4 (de) 2002-06-12
EP2093294A1 (de) 2009-08-26
TR200700740T2 (tr) 2007-04-24
CY1110679T1 (el) 2015-06-10
US20090162367A1 (en) 2009-06-25
BR9915137A (pt) 2004-06-08
RU2432364C2 (ru) 2011-10-27
PL204293B1 (pl) 2009-12-31
EP1124846A2 (de) 2001-08-22
HUP0301829A2 (hu) 2003-08-28
DE69941059D1 (de) 2009-08-13
EP2333064A1 (de) 2011-06-15
JP2012213406A (ja) 2012-11-08
US20050260616A1 (en) 2005-11-24
AU1469200A (en) 2000-06-13
KR100728405B1 (ko) 2007-06-13
EP1124846B1 (de) 2009-07-01

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