ATE435232T1 - Nukleotid- und proteinsequenzen von nogo-genen und darauf beruhende methoden - Google Patents

Nukleotid- und proteinsequenzen von nogo-genen und darauf beruhende methoden

Info

Publication number
ATE435232T1
ATE435232T1 AT99972673T AT99972673T ATE435232T1 AT E435232 T1 ATE435232 T1 AT E435232T1 AT 99972673 T AT99972673 T AT 99972673T AT 99972673 T AT99972673 T AT 99972673T AT E435232 T1 ATE435232 T1 AT E435232T1
Authority
AT
Austria
Prior art keywords
nucleotide
protein sequences
methods based
nogo
nogo genes
Prior art date
Application number
AT99972673T
Other languages
English (en)
Inventor
Martin Ernst Schwab
Maio Su Chen
Original Assignee
Univ Zuerich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22316666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE435232(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Zuerich filed Critical Univ Zuerich
Application granted granted Critical
Publication of ATE435232T1 publication Critical patent/ATE435232T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT99972673T 1998-11-06 1999-11-05 Nukleotid- und proteinsequenzen von nogo-genen und darauf beruhende methoden ATE435232T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10744698P 1998-11-06 1998-11-06
PCT/US1999/026160 WO2000031235A2 (en) 1998-11-06 1999-11-05 Nucleotide and protein sequences of nogo genes and methods based thereon

Publications (1)

Publication Number Publication Date
ATE435232T1 true ATE435232T1 (de) 2009-07-15

Family

ID=22316666

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99972673T ATE435232T1 (de) 1998-11-06 1999-11-05 Nukleotid- und proteinsequenzen von nogo-genen und darauf beruhende methoden

Country Status (26)

Country Link
US (4) US7781188B1 (de)
EP (3) EP2333064A1 (de)
JP (2) JP2003531566A (de)
KR (1) KR100728405B1 (de)
CN (3) CN1721444A (de)
AT (1) ATE435232T1 (de)
AU (1) AU774367C (de)
BR (1) BR9915137A (de)
CA (1) CA2350395C (de)
CY (1) CY1110679T1 (de)
CZ (1) CZ304224B6 (de)
DE (1) DE69941059D1 (de)
DK (1) DK1124846T3 (de)
ES (2) ES2329635T3 (de)
HU (1) HUP0301829A3 (de)
IL (3) IL142989A0 (de)
MX (1) MXPA01004598A (de)
NO (1) NO332460B1 (de)
NZ (1) NZ511683A (de)
PL (1) PL204293B1 (de)
PT (1) PT1124846E (de)
RU (3) RU2304585C2 (de)
SK (1) SK287323B6 (de)
TR (1) TR200700740T2 (de)
WO (1) WO2000031235A2 (de)
ZA (1) ZA200103714B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020072493A1 (en) * 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
JP2002522016A (ja) * 1998-07-22 2002-07-23 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 神経内分泌特異的タンパク質に類似したタンパク質、およびそれをコードするｃＤＮＡ
SK287323B6 (sk) 1998-11-06 2010-07-07 University Of Z�Rich Nogo proteín, jeho purifikovaný fragment, chimérny proteín a purifikovaná molekula s jeho obsahom, izolovaná nukleová kyselina, vektor s jej obsahom, rekombinantná bunka, spôsob produkcie rekombinantného proteínu a jeho použitie
US7186530B1 (en) 2000-04-07 2007-03-06 Chiron Corporation Protein associated with cell stress response
AU4216200A (en) * 1999-04-08 2000-10-23 Chiron Corporation Novel protein associated with cell stress response
HUP0203863A3 (en) * 2000-01-12 2008-03-28 Univ Yale Nogo receptor-mediated blockade of axonal growth
US7119165B2 (en) * 2000-01-12 2006-10-10 Yale University Nogo receptor-mediated blockade of axonal growth
US7049395B2 (en) 2000-05-02 2006-05-23 Yale University Anti-inflammatory compounds and uses thereof
ES2341608T3 (es) 2000-10-06 2010-06-23 Yale University Homologos del receptor de nogo.
GB0101312D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
GB0101313D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
AR040778A1 (es) 2002-08-06 2005-04-20 Glaxo Group Ltd Anticuerpos alterados o fragmentos funcionales que se unen a mag (glicoproteina asociada a mielina).
GB0228832D0 (en) 2002-12-10 2003-01-15 Novartis Ag Organic compound
US20060287501A1 (en) * 2002-10-31 2006-12-21 Pieris Proteolab Ag Soluble truncated polypeptides of the nogo-a protein
GB0306309D0 (en) 2003-03-19 2003-04-23 Glaxo Group Ltd Method of treatment
NZ548013A (en) * 2003-12-22 2009-04-30 Glaxo Group Ltd Immunoglobulins
PT1776136E (pt) 2004-06-24 2012-12-05 Biogen Idec Inc Tratamento de estados que envolvem desmielinização
KR100659820B1 (ko) 2004-11-17 2006-12-19 삼성에스디아이 주식회사 리튬 이온 이차 전지
US20090137484A1 (en) * 2004-12-01 2009-05-28 National University Of Singapore Neuronal Network-Interacting Peptide
EP1904091A4 (de) 2005-07-07 2009-12-23 Univ Yale Zusammensetzungen und verfahren zur unterdrückung der axonalen wachstumshemmung
SI1904104T1 (sl) 2005-07-08 2013-12-31 Biogen Idec Ma Inc. Protitelesa SP35 in njihova uporaba
US20070026463A1 (en) * 2005-07-28 2007-02-01 Wyeth Compositions and methods of mutant Nogo-66 domain proteins
JP2009515542A (ja) 2005-11-16 2009-04-16 ノバルティス アクチエンゲゼルシャフト 脊髄損傷における抗Ｎｏｇｏ−Ａ抗体処置のためのバイオマーカー
GB0525662D0 (en) 2005-12-16 2006-01-25 Glaxo Group Ltd Immunoglobulins
JP2009541211A (ja) * 2006-05-24 2009-11-26 ミエリン リペア ファウンデーション， インコーポレイテッド 血液脳関門の透過性
CN101015683B (zh) * 2007-01-18 2010-07-21 复旦大学 人rtn4b蛋白在制备创伤愈合药物中的应用
CA2704357C (en) * 2007-11-02 2016-06-21 Novartis Ag Improved nogo-a binding molecules and pharmaceutical use thereof
WO2009065414A1 (en) * 2007-11-22 2009-05-28 Symphogen A/S A method for characterization of a recombinant polyclonal protein
EP2315779A2 (de) 2008-07-09 2011-05-04 Biogen Idec MA Inc. Antikörper gegen lingo oder fragmente davon enthaltende zusammensetzungen
CN102439451B (zh) * 2009-06-02 2014-12-03 德克萨斯大学系统董事会 患神经退行性疾病的对象中抗体所识别的小分子的鉴定
US8828390B2 (en) 2010-07-09 2014-09-09 Universitat Zurich Uses of NOGO-A inhibitors and related methods
RU2478646C1 (ru) * 2011-11-28 2013-04-10 Федеральное государственное бюджетное учреждение науки Институт молекулярной биологии им.В.А.Энгельгардта Российской академии наук (ИМБ РАН) Способ получения высокоаффинных поликлональных антител
US9796780B2 (en) 2012-05-14 2017-10-24 Biogen Ma Inc. LINGO-2 antagonists for treatment of conditions involving motor neurons
EP3030171B1 (de) * 2013-08-08 2017-11-01 Global Bio Therapeutics, Inc. Injektionsvorrichtung für minimal invasive eingriffe
KR101685109B1 (ko) * 2014-12-22 2016-12-09 경북대학교 산학협력단 근육 분화, 재생, 또는 질환 상태와 관련된 노고-에이의 용도
WO2016112270A1 (en) 2015-01-08 2016-07-14 Biogen Ma Inc. Lingo-1 antagonists and uses for treatment of demyelinating disorders
JP2018505161A (ja) * 2015-01-27 2018-02-22 ウニヴェルズィテート チューリッヒ 膠芽腫の治療のためのＮｏｇｏ−Ａ Ｓ１ＰＲ経路のアゴニスト

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5A (en) * 1836-08-10 Thomas Blanchard Machine for mortising solid wooden shells of ships' tackle-blocks
US4196265A (en) * 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
CA1173823A (en) 1980-08-26 1984-09-04 Leonard M. Hjelmeland Nondenaturing zwitterionic detergent for membrane biochemistry
EP0155433A1 (de) 1984-03-23 1985-09-25 Adriano Fontana Immunsuppressionsfaktor
CA1341401C (en) 1984-03-23 2002-11-26 Adriano Fontana Immunosuppressant factor derived from human glioblastoma cells
EP0233838A3 (de) 1986-02-04 1990-01-31 Incyte Pharmaceuticals, Inc. Neuriten stimulierender Faktor und Prozess für seine Herstellung
US5091313A (en) * 1988-08-05 1992-02-25 Tanox Biosystems, Inc. Antigenic epitopes of IgE present on B cell but not basophil surface
EP0413763B1 (de) 1988-06-13 1996-11-06 American Biogenetic Sciences, Inc. Verfahren zur herstellung monoklonaler antikörper mit hilfe eines keimfreien tieres
CA1341050C (en) 1988-11-04 2000-07-11 Martin E. Schwab Neurite growth regulatory factors
US5250414A (en) 1988-11-04 1993-10-05 Erziehungsdirektion Of The Canton Zurich Diagnostic methods using neurite growth regulatory factors
EP0396719B1 (de) * 1988-11-04 1995-07-05 Erziehungsdirektion Of The Canton Zurich Wachstumsregelfaktoren für neuriten
AU2152092A (en) * 1991-06-24 1993-01-25 Erziehungsdirektion Of The Canton Zurich Neurite growth regulatory factors
US5858708A (en) * 1996-08-12 1999-01-12 Bandman; Olga Polynucleotides encoding two novel human neuroendocrine-specific proteins
CA2269755A1 (en) * 1996-10-25 1998-04-30 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1999033979A2 (en) * 1997-12-30 1999-07-08 Chiron Corporation Bone marrow secreted proteins and polynucleotides
US6607879B1 (en) * 1998-02-09 2003-08-19 Incyte Corporation Compositions for the detection of blood cell and immunological response gene expression
US20020072493A1 (en) * 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
JP2002522016A (ja) 1998-07-22 2002-07-23 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 神経内分泌特異的タンパク質に類似したタンパク質、およびそれをコードするｃＤＮＡ
WO2000011015A1 (en) * 1998-08-24 2000-03-02 Alphagene, Inc. Secreted proteins and polynucleotides encoding them
SK287323B6 (sk) 1998-11-06 2010-07-07 University Of Z�Rich Nogo proteín, jeho purifikovaný fragment, chimérny proteín a purifikovaná molekula s jeho obsahom, izolovaná nukleová kyselina, vektor s jej obsahom, rekombinantná bunka, spôsob produkcie rekombinantného proteínu a jeho použitie
WO2001036631A1 (en) * 1999-11-15 2001-05-25 Smithkline Beecham P.L.C. Human nogo-c polynucleotide and polypeptide and their uses
US20030134301A1 (en) * 2001-07-27 2003-07-17 Brooksbank Robert Alan Identification and use of molecules implicated in pain

Also Published As

Publication number Publication date
BR9915137A (pt) 2004-06-08
RU2009103533A (ru) 2010-11-10
ES2329635T3 (es) 2009-11-27
PL204293B1 (pl) 2009-12-31
KR20020003353A (ko) 2002-01-12
AU774367C (en) 2005-04-21
EP2093294A1 (de) 2009-08-26
WO2000031235A3 (en) 2000-11-09
TR200700740T2 (tr) 2007-04-24
RU2432364C2 (ru) 2011-10-27
SK287323B6 (sk) 2010-07-07
DE69941059D1 (de) 2009-08-13
EP2333064A1 (de) 2011-06-15
NZ511683A (en) 2004-06-25
US20050260616A1 (en) 2005-11-24
ES2529196T3 (es) 2015-02-17
US7781188B1 (en) 2010-08-24
RU2358982C2 (ru) 2009-06-20
RU2304585C2 (ru) 2007-08-20
CN1354755B (zh) 2010-06-02
IL142989A (en) 2010-12-30
CN1354755A (zh) 2002-06-19
PT1124846E (pt) 2009-10-08
RU2001115705A (ru) 2004-03-10
CN101684155A (zh) 2010-03-31
AU774367B2 (en) 2004-06-24
NO20012223D0 (no) 2001-05-04
CA2350395C (en) 2014-07-08
CN1721444A (zh) 2006-01-18
RU2004103555A (ru) 2005-07-20
EP1124846A2 (de) 2001-08-22
DK1124846T3 (da) 2009-10-26
EP2093294B1 (de) 2014-10-29
CA2350395A1 (en) 2000-06-02
US7425334B2 (en) 2008-09-16
SK6222001A3 (en) 2001-12-03
US20110086034A1 (en) 2011-04-14
US20090162367A1 (en) 2009-06-25
JP2003531566A (ja) 2003-10-28
NO332460B1 (no) 2012-09-24
EP1124846A4 (de) 2002-06-12
KR100728405B1 (ko) 2007-06-13
CY1110679T1 (el) 2015-06-10
PL362990A1 (en) 2004-11-15
HUP0301829A2 (hu) 2003-08-28
AU1469200A (en) 2000-06-13
CZ304224B6 (cs) 2014-01-15
NO20012223L (no) 2001-07-02
JP2012213406A (ja) 2012-11-08
IL198027A (en) 2011-10-31
MXPA01004598A (es) 2002-04-24
CZ20011608A3 (cs) 2001-10-17
HK1038027A1 (en) 2002-03-01
ZA200103714B (en) 2004-06-25
IL142989A0 (en) 2002-04-21
WO2000031235A2 (en) 2000-06-02
EP1124846B1 (de) 2009-07-01
HUP0301829A3 (en) 2009-03-30

Similar Documents

Publication Publication Date Title
DE69941059D1 (de) Nukleotid- und proteinsequenzen von nogo-genen und darauf beruhende methoden
ATE389016T2 (de) Sirna knockout prüfverfahren und konstrukte
DE69638023D1 (de) Nukleotid- und proteinsequenzen von delta-genen von vertebraten und darauf basierende methoden
EA200101037A1 (ru) Соединения и способы для лечения и диагностики рака легкого
ATE407949T1 (de) Charakterisierung der proteinfamilie von soc/crac kalziumkanälen
DE69434166D1 (de) Menschliche metabotropische glutamatrezeptor untertype hmglur7 und verwandte dns-verbindungen
DE60232870D1 (de) Neue polynukleotide und polypeptide des erythropoietingens
DE69833784D1 (de) Polypeptide mit aminopeptidaseaktivität und für diese kodierende nukleinsäuren
DE69841994D1 (de) 32 Humane sekretierte Proteine
HUP9800329A2 (hu) Nukleinsavkonstrukciók strukturális gének sejtciklus-függő módon szabályozott expresszálására
DE69837475D1 (de) Polypeptide mit aminopeptidaseaktivität und dafür kodierende nukleinsäuren
DK1536006T3 (da) Cancerantigener og anvendelse deraf
DE69734644D1 (de) Carboxypeptidasen aus aspergillus oryzae und diese kodierende nukleinsäuren
ATE348161T1 (de) Fctrx genannte proteine und dafür kodierende nuklein säure
WO1999063094A3 (en) Nucleotide and protein sequences of gpr1 and methods based thereon
ATE132192T1 (de) Rekombinantes produkt
MX9805158A (es) Adn que codifica una proteina activadora de plasminogeno.
ATE278011T1 (de) Human dnase ii
WO2003052377A9 (en) 41 human secreted proteins
WO2003040320A3 (en) Antisense modulation of human collapsin response mediator protein 2 expression
AU8499501A (en) Slo2 and slo4, novel potassium channel proteins from human brain
WO2003091393A3 (en) Nucleic “acid molecules encoding human proteins, and uses thereof”
WO2003080797A3 (en) 6 human secreted proteins

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1124846

Country of ref document: EP