DK1124846T3 - Nukleotid- og proteinsekvenser af Nogo-gener og derpå baserede fremgangsmåder - Google Patents

Nukleotid- og proteinsekvenser af Nogo-gener og derpå baserede fremgangsmåder

Info

Publication number
DK1124846T3
DK1124846T3 DK99972673T DK99972673T DK1124846T3 DK 1124846 T3 DK1124846 T3 DK 1124846T3 DK 99972673 T DK99972673 T DK 99972673T DK 99972673 T DK99972673 T DK 99972673T DK 1124846 T3 DK1124846 T3 DK 1124846T3
Authority
DK
Denmark
Prior art keywords
nucleotide
protein sequences
methods based
nogo
nogo genes
Prior art date
Application number
DK99972673T
Other languages
English (en)
Inventor
Martin Ernst Schwab
Maio Su Chen
Original Assignee
Univ Zuerich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22316666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1124846(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Zuerich filed Critical Univ Zuerich
Application granted granted Critical
Publication of DK1124846T3 publication Critical patent/DK1124846T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DK99972673T 1998-11-06 1999-11-05 Nukleotid- og proteinsekvenser af Nogo-gener og derpå baserede fremgangsmåder DK1124846T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10744698P 1998-11-06 1998-11-06
PCT/US1999/026160 WO2000031235A2 (en) 1998-11-06 1999-11-05 Nucleotide and protein sequences of nogo genes and methods based thereon

Publications (1)

Publication Number Publication Date
DK1124846T3 true DK1124846T3 (da) 2009-10-26

Family

ID=22316666

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99972673T DK1124846T3 (da) 1998-11-06 1999-11-05 Nukleotid- og proteinsekvenser af Nogo-gener og derpå baserede fremgangsmåder

Country Status (26)

Country Link
US (4) US7781188B1 (da)
EP (3) EP2333064A1 (da)
JP (2) JP2003531566A (da)
KR (1) KR100728405B1 (da)
CN (3) CN1721444A (da)
AT (1) ATE435232T1 (da)
AU (1) AU774367C (da)
BR (1) BR9915137A (da)
CA (1) CA2350395C (da)
CY (1) CY1110679T1 (da)
CZ (1) CZ304224B6 (da)
DE (1) DE69941059D1 (da)
DK (1) DK1124846T3 (da)
ES (2) ES2529196T3 (da)
HU (1) HUP0301829A3 (da)
IL (3) IL142989A0 (da)
MX (1) MXPA01004598A (da)
NO (1) NO332460B1 (da)
NZ (1) NZ511683A (da)
PL (1) PL204293B1 (da)
PT (1) PT1124846E (da)
RU (3) RU2304585C2 (da)
SK (1) SK287323B6 (da)
TR (1) TR200700740T2 (da)
WO (1) WO2000031235A2 (da)
ZA (1) ZA200103714B (da)

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DE69942803D1 (de) * 1998-07-22 2010-11-11 Smithkline Beecham Ltd Rotein änhelt, und dafür kodierende cdns
CZ304224B6 (cs) 1998-11-06 2014-01-15 Schwab Monoklonální protilátka
AU4216200A (en) * 1999-04-08 2000-10-23 Chiron Corporation Novel protein associated with cell stress response
US7186530B1 (en) 2000-04-07 2007-03-06 Chiron Corporation Protein associated with cell stress response
IL150566A0 (en) * 2000-01-12 2003-02-12 Univ Yale Nucleic acids and polypeptides and nogo-receptor proteins
US7119165B2 (en) * 2000-01-12 2006-10-10 Yale University Nogo receptor-mediated blockade of axonal growth
US7049395B2 (en) 2000-05-02 2006-05-23 Yale University Anti-inflammatory compounds and uses thereof
NZ525422A (en) 2000-10-06 2006-09-29 Biogen Idec Inc Isolated polynucleotides comprising a nucleic acid which encodes a polypeptide which modulates axonal growth in CNS neurons
GB0101312D0 (en) 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
GB0101313D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
TWI323265B (en) 2002-08-06 2010-04-11 Glaxo Group Ltd Antibodies
GB0228832D0 (en) 2002-12-10 2003-01-15 Novartis Ag Organic compound
US20060287501A1 (en) * 2002-10-31 2006-12-21 Pieris Proteolab Ag Soluble truncated polypeptides of the nogo-a protein
GB0306309D0 (en) 2003-03-19 2003-04-23 Glaxo Group Ltd Method of treatment
CA2549956C (en) * 2003-12-22 2016-04-12 Glaxo Group Limited Immunoglobulins
PT1776136E (pt) 2004-06-24 2012-12-05 Biogen Idec Inc Tratamento de estados que envolvem desmielinização
KR100659820B1 (ko) 2004-11-17 2006-12-19 삼성에스디아이 주식회사 리튬 이온 이차 전지
US20090137484A1 (en) * 2004-12-01 2009-05-28 National University Of Singapore Neuronal Network-Interacting Peptide
US7893032B2 (en) 2005-07-07 2011-02-22 Yale University NgR variants and compositions thereof for suppressing axonal growth inhibition
SI1904104T1 (sl) 2005-07-08 2013-12-31 Biogen Idec Ma Inc. Protitelesa SP35 in njihova uporaba
US20070026463A1 (en) * 2005-07-28 2007-02-01 Wyeth Compositions and methods of mutant Nogo-66 domain proteins
CA2627966A1 (en) 2005-11-16 2007-05-24 Novartis Ag Biomarkers for anti-nogo-a antibody treatment in spinal cord injury
GB0525662D0 (en) 2005-12-16 2006-01-25 Glaxo Group Ltd Immunoglobulins
WO2007137303A2 (en) * 2006-05-24 2007-11-29 Myelin Repair Foundation, Inc. Permeability of blood-brain barrier
CN101015683B (zh) * 2007-01-18 2010-07-21 复旦大学 人rtn4b蛋白在制备创伤愈合药物中的应用
HRP20130699T1 (hr) * 2007-11-02 2013-11-22 Novartis Ag Poboljšane molekule koje se vežu na nogo-a i njihova farmaceutska uporaba
CA2702322A1 (en) * 2007-11-22 2009-05-28 Symphogen A/S A method for characterization of a recombinant polyclonal protein
DK2982695T3 (da) 2008-07-09 2019-05-13 Biogen Ma Inc Sammensætninger, der omfatter antistoffer mod lingo eller fragmenter deraf
BRPI1013012A2 (pt) * 2009-06-02 2016-10-18 Opko Health Inc identificação de pequenas moléculas reconhecidas por anticorpos em indivíduos com doenças neurodegenerativas
WO2012004773A1 (en) 2010-07-09 2012-01-12 Universite De Geneve New uses of nogo-a inhibitors and related methods
RU2478646C1 (ru) * 2011-11-28 2013-04-10 Федеральное государственное бюджетное учреждение науки Институт молекулярной биологии им.В.А.Энгельгардта Российской академии наук (ИМБ РАН) Способ получения высокоаффинных поликлональных антител
CN104470541A (zh) 2012-05-14 2015-03-25 比奥根艾迪克Ma公司 用于治疗涉及运动神经元的疾患的lingo-2拮抗剂
HK1225257B (en) 2013-08-08 2017-09-08 Global Bio Therapeutics, Inc. Injection device for minimally invasive surgical procedures
KR101685109B1 (ko) * 2014-12-22 2016-12-09 경북대학교 산학협력단 근육 분화, 재생, 또는 질환 상태와 관련된 노고-에이의 용도
JP2018504400A (ja) 2015-01-08 2018-02-15 バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． Ｌｉｎｇｏ‐１拮抗薬及び脱髄障害の治療のための使用
EP3250220B1 (en) * 2015-01-27 2020-03-11 Universität Zürich Agonists of the nogo-a s1pr pathway for the treatment of glioblastoma

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US4196265A (en) * 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
CA1173823A (en) 1980-08-26 1984-09-04 Leonard M. Hjelmeland Nondenaturing zwitterionic detergent for membrane biochemistry
EP0155433A1 (en) 1984-03-23 1985-09-25 Adriano Fontana Immunosuppressant factor
CA1341401C (en) 1984-03-23 2002-11-26 Adriano Fontana Immunosuppressant factor derived from human glioblastoma cells
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US5091313A (en) * 1988-08-05 1992-02-25 Tanox Biosystems, Inc. Antigenic epitopes of IgE present on B cell but not basophil surface
WO1989012690A1 (en) 1988-06-13 1989-12-28 American Biogentic Sciences, Inc. Method for the production of monoclonal antibodies utilizing a germfree animal
DE68923362T2 (de) 1988-11-04 1996-03-28 Zuerich Erziehungsdirektion Wachstumsregelfaktoren für neuriten.
US5250414A (en) 1988-11-04 1993-10-05 Erziehungsdirektion Of The Canton Zurich Diagnostic methods using neurite growth regulatory factors
CA1341050C (en) * 1988-11-04 2000-07-11 Martin E. Schwab Neurite growth regulatory factors
WO1993000427A2 (en) * 1991-06-24 1993-01-07 Erziehungsdirektion Of The Canton Zurich Neurite growth regulatory factors
US5858708A (en) * 1996-08-12 1999-01-12 Bandman; Olga Polynucleotides encoding two novel human neuroendocrine-specific proteins
WO1998017687A2 (en) * 1996-10-25 1998-04-30 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
JP2002511231A (ja) * 1997-12-30 2002-04-16 カイロン コーポレイション 骨髄分泌タンパク質およびポリヌクレオチド
US6607879B1 (en) * 1998-02-09 2003-08-19 Incyte Corporation Compositions for the detection of blood cell and immunological response gene expression
US20020072493A1 (en) * 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
DE69942803D1 (de) * 1998-07-22 2010-11-11 Smithkline Beecham Ltd Rotein änhelt, und dafür kodierende cdns
AU5784799A (en) * 1998-08-24 2000-03-14 Alphagene, Inc. Secreted proteins and polynucleotides encoding them
CZ304224B6 (cs) 1998-11-06 2014-01-15 Schwab Monoklonální protilátka
WO2001036631A1 (en) * 1999-11-15 2001-05-25 Smithkline Beecham P.L.C. Human nogo-c polynucleotide and polypeptide and their uses
US20030134301A1 (en) * 2001-07-27 2003-07-17 Brooksbank Robert Alan Identification and use of molecules implicated in pain

Also Published As

Publication number Publication date
MXPA01004598A (es) 2002-04-24
HUP0301829A2 (hu) 2003-08-28
AU774367B2 (en) 2004-06-24
HK1038027A1 (en) 2002-03-01
RU2304585C2 (ru) 2007-08-20
CN101684155A (zh) 2010-03-31
JP2003531566A (ja) 2003-10-28
NO20012223D0 (no) 2001-05-04
US7781188B1 (en) 2010-08-24
RU2004103555A (ru) 2005-07-20
NZ511683A (en) 2004-06-25
US20110086034A1 (en) 2011-04-14
WO2000031235A3 (en) 2000-11-09
CN1721444A (zh) 2006-01-18
CA2350395C (en) 2014-07-08
RU2009103533A (ru) 2010-11-10
US7425334B2 (en) 2008-09-16
SK287323B6 (sk) 2010-07-07
CY1110679T1 (el) 2015-06-10
EP2093294A1 (en) 2009-08-26
ES2329635T3 (es) 2009-11-27
CN1354755B (zh) 2010-06-02
US20050260616A1 (en) 2005-11-24
HUP0301829A3 (en) 2009-03-30
IL142989A (en) 2010-12-30
RU2001115705A (ru) 2004-03-10
RU2432364C2 (ru) 2011-10-27
BR9915137A (pt) 2004-06-08
AU1469200A (en) 2000-06-13
CZ304224B6 (cs) 2014-01-15
EP1124846A4 (en) 2002-06-12
CA2350395A1 (en) 2000-06-02
CZ20011608A3 (cs) 2001-10-17
RU2358982C2 (ru) 2009-06-20
EP2093294B1 (en) 2014-10-29
ATE435232T1 (de) 2009-07-15
IL198027A (en) 2011-10-31
KR100728405B1 (ko) 2007-06-13
US20090162367A1 (en) 2009-06-25
SK6222001A3 (en) 2001-12-03
PL362990A1 (en) 2004-11-15
PT1124846E (pt) 2009-10-08
IL142989A0 (en) 2002-04-21
JP2012213406A (ja) 2012-11-08
DE69941059D1 (de) 2009-08-13
EP2333064A1 (en) 2011-06-15
PL204293B1 (pl) 2009-12-31
NO332460B1 (no) 2012-09-24
NO20012223L (no) 2001-07-02
ZA200103714B (en) 2004-06-25
AU774367C (en) 2005-04-21
TR200700740T2 (tr) 2007-04-24
EP1124846B1 (en) 2009-07-01
WO2000031235A2 (en) 2000-06-02
KR20020003353A (ko) 2002-01-12
EP1124846A2 (en) 2001-08-22
ES2529196T3 (es) 2015-02-17
CN1354755A (zh) 2002-06-19

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