DK1124846T3 - Nukleotid- og proteinsekvenser af Nogo-gener og derpå baserede fremgangsmåder - Google Patents

Nukleotid- og proteinsekvenser af Nogo-gener og derpå baserede fremgangsmåder

Info

Publication number
DK1124846T3
DK1124846T3 DK99972673T DK99972673T DK1124846T3 DK 1124846 T3 DK1124846 T3 DK 1124846T3 DK 99972673 T DK99972673 T DK 99972673T DK 99972673 T DK99972673 T DK 99972673T DK 1124846 T3 DK1124846 T3 DK 1124846T3
Authority
DK
Denmark
Prior art keywords
nucleotide
protein sequences
methods based
nogo
nogo genes
Prior art date
Application number
DK99972673T
Other languages
English (en)
Inventor
Martin Ernst Schwab
Maio Su Chen
Original Assignee
Univ Zuerich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22316666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1124846(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Zuerich filed Critical Univ Zuerich
Application granted granted Critical
Publication of DK1124846T3 publication Critical patent/DK1124846T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DK99972673T 1998-11-06 1999-11-05 Nukleotid- og proteinsekvenser af Nogo-gener og derpå baserede fremgangsmåder DK1124846T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10744698P 1998-11-06 1998-11-06
PCT/US1999/026160 WO2000031235A2 (en) 1998-11-06 1999-11-05 Nucleotide and protein sequences of nogo genes and methods based thereon

Publications (1)

Publication Number Publication Date
DK1124846T3 true DK1124846T3 (da) 2009-10-26

Family

ID=22316666

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99972673T DK1124846T3 (da) 1998-11-06 1999-11-05 Nukleotid- og proteinsekvenser af Nogo-gener og derpå baserede fremgangsmåder

Country Status (26)

Country Link
US (4) US7781188B1 (da)
EP (3) EP2333064A1 (da)
JP (2) JP2003531566A (da)
KR (1) KR100728405B1 (da)
CN (3) CN1721444A (da)
AT (1) ATE435232T1 (da)
AU (1) AU774367C (da)
BR (1) BR9915137A (da)
CA (1) CA2350395C (da)
CY (1) CY1110679T1 (da)
CZ (1) CZ304224B6 (da)
DE (1) DE69941059D1 (da)
DK (1) DK1124846T3 (da)
ES (2) ES2329635T3 (da)
HU (1) HUP0301829A3 (da)
IL (3) IL142989A0 (da)
MX (1) MXPA01004598A (da)
NO (1) NO332460B1 (da)
NZ (1) NZ511683A (da)
PL (1) PL204293B1 (da)
PT (1) PT1124846E (da)
RU (3) RU2304585C2 (da)
SK (1) SK287323B6 (da)
TR (1) TR200700740T2 (da)
WO (1) WO2000031235A2 (da)
ZA (1) ZA200103714B (da)

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SK287323B6 (sk) 1998-11-06 2010-07-07 University Of Z�Rich Nogo proteín, jeho purifikovaný fragment, chimérny proteín a purifikovaná molekula s jeho obsahom, izolovaná nukleová kyselina, vektor s jej obsahom, rekombinantná bunka, spôsob produkcie rekombinantného proteínu a jeho použitie
US7186530B1 (en) 2000-04-07 2007-03-06 Chiron Corporation Protein associated with cell stress response
AU4216200A (en) * 1999-04-08 2000-10-23 Chiron Corporation Novel protein associated with cell stress response
HUP0203863A3 (en) * 2000-01-12 2008-03-28 Univ Yale Nogo receptor-mediated blockade of axonal growth
US7119165B2 (en) * 2000-01-12 2006-10-10 Yale University Nogo receptor-mediated blockade of axonal growth
US7049395B2 (en) 2000-05-02 2006-05-23 Yale University Anti-inflammatory compounds and uses thereof
ES2341608T3 (es) 2000-10-06 2010-06-23 Yale University Homologos del receptor de nogo.
GB0101312D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
GB0101313D0 (en) * 2001-01-18 2001-02-28 Glaxo Group Ltd Assay
AR040778A1 (es) 2002-08-06 2005-04-20 Glaxo Group Ltd Anticuerpos alterados o fragmentos funcionales que se unen a mag (glicoproteina asociada a mielina).
GB0228832D0 (en) 2002-12-10 2003-01-15 Novartis Ag Organic compound
US20060287501A1 (en) * 2002-10-31 2006-12-21 Pieris Proteolab Ag Soluble truncated polypeptides of the nogo-a protein
GB0306309D0 (en) 2003-03-19 2003-04-23 Glaxo Group Ltd Method of treatment
NZ548013A (en) * 2003-12-22 2009-04-30 Glaxo Group Ltd Immunoglobulins
PT1776136E (pt) 2004-06-24 2012-12-05 Biogen Idec Inc Tratamento de estados que envolvem desmielinização
KR100659820B1 (ko) 2004-11-17 2006-12-19 삼성에스디아이 주식회사 리튬 이온 이차 전지
US20090137484A1 (en) * 2004-12-01 2009-05-28 National University Of Singapore Neuronal Network-Interacting Peptide
EP1904091A4 (en) 2005-07-07 2009-12-23 Univ Yale COMPOSITIONS AND METHODS FOR SUPPRESSING THE INHIBITION OF AXON GROWTH
SI1904104T1 (sl) 2005-07-08 2013-12-31 Biogen Idec Ma Inc. Protitelesa SP35 in njihova uporaba
US20070026463A1 (en) * 2005-07-28 2007-02-01 Wyeth Compositions and methods of mutant Nogo-66 domain proteins
JP2009515542A (ja) 2005-11-16 2009-04-16 ノバルティス アクチエンゲゼルシャフト 脊髄損傷における抗Ｎｏｇｏ−Ａ抗体処置のためのバイオマーカー
GB0525662D0 (en) 2005-12-16 2006-01-25 Glaxo Group Ltd Immunoglobulins
JP2009541211A (ja) * 2006-05-24 2009-11-26 ミエリン リペア ファウンデーション， インコーポレイテッド 血液脳関門の透過性
CN101015683B (zh) * 2007-01-18 2010-07-21 复旦大学 人rtn4b蛋白在制备创伤愈合药物中的应用
CA2704357C (en) * 2007-11-02 2016-06-21 Novartis Ag Improved nogo-a binding molecules and pharmaceutical use thereof
WO2009065414A1 (en) * 2007-11-22 2009-05-28 Symphogen A/S A method for characterization of a recombinant polyclonal protein
EP2315779A2 (en) 2008-07-09 2011-05-04 Biogen Idec MA Inc. Compositions comprising antibodies to lingo or fragments thereof
CN102439451B (zh) * 2009-06-02 2014-12-03 德克萨斯大学系统董事会 患神经退行性疾病的对象中抗体所识别的小分子的鉴定
US8828390B2 (en) 2010-07-09 2014-09-09 Universitat Zurich Uses of NOGO-A inhibitors and related methods
RU2478646C1 (ru) * 2011-11-28 2013-04-10 Федеральное государственное бюджетное учреждение науки Институт молекулярной биологии им.В.А.Энгельгардта Российской академии наук (ИМБ РАН) Способ получения высокоаффинных поликлональных антител
US9796780B2 (en) 2012-05-14 2017-10-24 Biogen Ma Inc. LINGO-2 antagonists for treatment of conditions involving motor neurons
EP3030171B1 (en) * 2013-08-08 2017-11-01 Global Bio Therapeutics, Inc. Injection device for minimally invasive procedures
KR101685109B1 (ko) * 2014-12-22 2016-12-09 경북대학교 산학협력단 근육 분화, 재생, 또는 질환 상태와 관련된 노고-에이의 용도
WO2016112270A1 (en) 2015-01-08 2016-07-14 Biogen Ma Inc. Lingo-1 antagonists and uses for treatment of demyelinating disorders
JP2018505161A (ja) * 2015-01-27 2018-02-22 ウニヴェルズィテート チューリッヒ 膠芽腫の治療のためのＮｏｇｏ−Ａ Ｓ１ＰＲ経路のアゴニスト

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Also Published As

Publication number Publication date
BR9915137A (pt) 2004-06-08
RU2009103533A (ru) 2010-11-10
ES2329635T3 (es) 2009-11-27
PL204293B1 (pl) 2009-12-31
KR20020003353A (ko) 2002-01-12
AU774367C (en) 2005-04-21
EP2093294A1 (en) 2009-08-26
WO2000031235A3 (en) 2000-11-09
TR200700740T2 (tr) 2007-04-24
RU2432364C2 (ru) 2011-10-27
SK287323B6 (sk) 2010-07-07
DE69941059D1 (de) 2009-08-13
EP2333064A1 (en) 2011-06-15
NZ511683A (en) 2004-06-25
US20050260616A1 (en) 2005-11-24
ES2529196T3 (es) 2015-02-17
US7781188B1 (en) 2010-08-24
RU2358982C2 (ru) 2009-06-20
RU2304585C2 (ru) 2007-08-20
CN1354755B (zh) 2010-06-02
IL142989A (en) 2010-12-30
CN1354755A (zh) 2002-06-19
PT1124846E (pt) 2009-10-08
RU2001115705A (ru) 2004-03-10
CN101684155A (zh) 2010-03-31
AU774367B2 (en) 2004-06-24
NO20012223D0 (no) 2001-05-04
CA2350395C (en) 2014-07-08
CN1721444A (zh) 2006-01-18
RU2004103555A (ru) 2005-07-20
EP1124846A2 (en) 2001-08-22
ATE435232T1 (de) 2009-07-15
EP2093294B1 (en) 2014-10-29
CA2350395A1 (en) 2000-06-02
US7425334B2 (en) 2008-09-16
SK6222001A3 (en) 2001-12-03
US20110086034A1 (en) 2011-04-14
US20090162367A1 (en) 2009-06-25
JP2003531566A (ja) 2003-10-28
NO332460B1 (no) 2012-09-24
EP1124846A4 (en) 2002-06-12
KR100728405B1 (ko) 2007-06-13
CY1110679T1 (el) 2015-06-10
PL362990A1 (en) 2004-11-15
HUP0301829A2 (hu) 2003-08-28
AU1469200A (en) 2000-06-13
CZ304224B6 (cs) 2014-01-15
NO20012223L (no) 2001-07-02
JP2012213406A (ja) 2012-11-08
IL198027A (en) 2011-10-31
MXPA01004598A (es) 2002-04-24
CZ20011608A3 (cs) 2001-10-17
HK1038027A1 (en) 2002-03-01
ZA200103714B (en) 2004-06-25
IL142989A0 (en) 2002-04-21
WO2000031235A2 (en) 2000-06-02
EP1124846B1 (en) 2009-07-01
HUP0301829A3 (en) 2009-03-30

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