ATE435654T1 - Manipulierte proteine zum analyten nachweis - Google Patents

Manipulierte proteine zum analyten nachweis

Info

Publication number
ATE435654T1
ATE435654T1 AT99935583T AT99935583T ATE435654T1 AT E435654 T1 ATE435654 T1 AT E435654T1 AT 99935583 T AT99935583 T AT 99935583T AT 99935583 T AT99935583 T AT 99935583T AT E435654 T1 ATE435654 T1 AT E435654T1
Authority
AT
Austria
Prior art keywords
analyte detection
manipulated
proteins
analyte
manipulated proteins
Prior art date
Application number
AT99935583T
Other languages
English (en)
Inventor
Joseph Lakowicz
Leah Tolosa
Lisa Eichhorn
Govind Rao
Original Assignee
Univ Maryland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Maryland filed Critical Univ Maryland
Application granted granted Critical
Publication of ATE435654T1 publication Critical patent/ATE435654T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
AT99935583T 1998-07-17 1999-07-15 Manipulierte proteine zum analyten nachweis ATE435654T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9318898P 1998-07-17 1998-07-17
US10423798P 1998-10-14 1998-10-14
PCT/US1999/015998 WO2000003727A1 (en) 1998-07-17 1999-07-15 Engineered proteins for analyte sensing

Publications (1)

Publication Number Publication Date
ATE435654T1 true ATE435654T1 (de) 2009-07-15

Family

ID=26787240

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99935583T ATE435654T1 (de) 1998-07-17 1999-07-15 Manipulierte proteine zum analyten nachweis

Country Status (9)

Country Link
US (1) US6197534B1 (de)
EP (1) EP1098658B1 (de)
AT (1) ATE435654T1 (de)
AU (1) AU759888B2 (de)
CA (1) CA2336985C (de)
DE (1) DE69941085D1 (de)
DK (1) DK1098658T3 (de)
ES (1) ES2329850T3 (de)
WO (1) WO2000003727A1 (de)

Families Citing this family (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544193B2 (en) * 1996-09-04 2003-04-08 Marcio Marc Abreu Noninvasive measurement of chemical substances
US6120460A (en) * 1996-09-04 2000-09-19 Abreu; Marcio Marc Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions
US20020158212A1 (en) * 1998-04-17 2002-10-31 French Todd E. Apparatus and methods for time-resolved optical spectroscopy
US6922576B2 (en) * 1998-06-19 2005-07-26 Becton, Dickinson And Company Micro optical sensor device
US6535753B1 (en) * 1998-08-20 2003-03-18 Microsense International, Llc Micro-invasive method for painless detection of analytes in extra-cellular space
CA2381520C (en) 1999-08-26 2009-05-26 Novartis Ag Ocular analyte sensor
US7332567B2 (en) * 2001-08-28 2008-02-19 Allergan, Inc. Fret protease assays for clostridial toxins
CA2457964C (en) * 2001-08-28 2013-05-28 Duke University Biosensor
US8022172B2 (en) * 2001-08-28 2011-09-20 Allergan, Inc. Luminescence resonance energy transfer (LRET) assays for clostridial toxin activity
US7374896B2 (en) * 2001-08-28 2008-05-20 Allergan, Inc. GFP-SNAP25 fluorescence release assay for botulinum neurotoxin protease activity
EP2284195A1 (de) * 2001-09-18 2011-02-16 Carnegie Institution Of Washington Fusionsproteine zur Detektion von Analyten
US20030232383A1 (en) * 2001-11-02 2003-12-18 Sylvia Daunert Novel reagentless sensing system for measuring carbohydrates based on the galactose/glucose binding protein
US7851593B2 (en) * 2002-01-04 2010-12-14 Becton, Dickinson And Company Binding proteins as biosensors
US7064103B2 (en) * 2002-01-04 2006-06-20 Becton, Dickinson And Company Binding protein as biosensors
US6855556B2 (en) * 2002-01-04 2005-02-15 Becton, Dickinson And Company Binding protein as biosensors
US20050239155A1 (en) * 2002-01-04 2005-10-27 Javier Alarcon Entrapped binding protein as biosensors
US20030153026A1 (en) * 2002-01-04 2003-08-14 Javier Alarcon Entrapped binding protein as biosensors
US20030232370A1 (en) * 2002-04-22 2003-12-18 Trifiro Mark A. Glucose sensor and uses thereof
US8328420B2 (en) 2003-04-22 2012-12-11 Marcio Marc Abreu Apparatus and method for measuring biologic parameters
US9848815B2 (en) 2002-04-22 2017-12-26 Geelux Holdings, Ltd. Apparatus and method for measuring biologic parameters
AU2003272191B2 (en) 2002-04-22 2008-07-03 Abreu, Marcio Marc Aurelio Martins Apparatus and method for measuring biologic parameters
US8849379B2 (en) * 2002-04-22 2014-09-30 Geelux Holdings, Ltd. Apparatus and method for measuring biologic parameters
US20050118726A1 (en) * 2002-08-26 2005-06-02 Schultz Jerome S. System and method for detecting bioanalytes and method for producing a bioanalyte sensor
US7244394B2 (en) 2002-10-03 2007-07-17 Novartis Ag Methods and kits for assays of analytes of interest in tears
US9625458B2 (en) * 2002-10-16 2017-04-18 Duke University Biosensor
DE60324331D1 (de) * 2002-12-20 2008-12-04 Univ Wuerzburg J Maximilians Millisekunden-aktivationsschalter für 7-transmembran-proteine
US20040229290A1 (en) * 2003-05-07 2004-11-18 Duke University Protein design for receptor-ligand recognition and binding
WO2004101769A2 (en) * 2003-05-09 2004-11-25 University Of Maryland Baltimore County Proteins, sensors, and methods of characterizing analytes using the same
EP2259050A3 (de) * 2003-08-26 2010-12-22 Blueshift Biotechnologies, Inc. Zeitabhängige Fluoreszenzmessungen
US7214190B1 (en) * 2003-09-09 2007-05-08 Kitchener Clark Wilson Apparatus and method for noninvasive monitoring of analytes in body fluids
US7787923B2 (en) * 2003-11-26 2010-08-31 Becton, Dickinson And Company Fiber optic device for sensing analytes and method of making same
US20050112685A1 (en) * 2003-11-26 2005-05-26 Amiss Terry J. Compositions and methods for measuring analyte concentrations
US7496392B2 (en) 2003-11-26 2009-02-24 Becton, Dickinson And Company Fiber optic device for sensing analytes
WO2005081801A2 (en) * 2004-02-09 2005-09-09 Blueshift Biotechnologies, Inc. Methods and apparatus for scanning small sample volumes
US10227063B2 (en) 2004-02-26 2019-03-12 Geelux Holdings, Ltd. Method and apparatus for biological evaluation
US7563891B2 (en) 2004-05-21 2009-07-21 Becton, Dickinson & Company Long wavelength thiol-reactive fluorophores
DK1759536T3 (da) 2004-06-01 2011-09-05 Kwalata Trading Ltd In vitro-teknikker til anvendelse med stamceller
EP1754059B1 (de) * 2004-06-09 2010-08-04 Becton, Dickinson and Company Sensor für mehrere analyte
DK1758500T3 (da) * 2004-06-14 2010-01-18 Eyesense Ag Kombineret apparat til måling af blodglukoseniveauet ud fra en øjenvæske
WO2006014351A2 (en) * 2004-07-02 2006-02-09 Blueshift Biotechnologies, Inc. Exploring fluorophore microenvironments
WO2006006166A2 (en) * 2004-07-14 2006-01-19 Glusense, Ltd. Implantable power sources and sensors
US7399607B2 (en) * 2004-09-22 2008-07-15 Allergan, Inc. Fluorescence polarization assays for determining clostridial toxin activity
EP1815246A4 (de) * 2004-10-14 2009-12-16 Carnegie Inst Of Washington Entwicklung von empfindlichen fret-sensoren und verwendungsverfahren dafür
WO2006044611A2 (en) * 2004-10-14 2006-04-27 Carnegie Institution Of Washington Neurotransmitter sensors and methods of using the same
CA2592412A1 (en) * 2004-12-24 2006-06-29 Leiden University Novel use of fluorescence resonance energy transfer
US20090178149A1 (en) * 2005-03-03 2009-07-09 Sylvie Lalonde Polyamine Sensors and Methods of Using the Same
CA2599852A1 (en) * 2005-03-04 2006-09-14 Carnegie Institution Of Washington Environmentally stable sensors and methods of using the same
WO2006096746A1 (en) * 2005-03-11 2006-09-14 Becton, Dickinson And Company Entrapped binding protein as biosensors
US20060224056A1 (en) * 2005-03-30 2006-10-05 Kermani Mahyar Z Method for monitoring an implanted fluorescent light-emitting bead
US7687263B2 (en) 2005-05-11 2010-03-30 Becton, Dickinson And Company In vitro tumor angiogenesis model
KR100739529B1 (ko) * 2005-07-25 2007-07-13 한국생명공학연구원 세포내 맥아당의 정량적 측정을 위한 맥아당 바이오센서
US20070038045A1 (en) * 2005-08-09 2007-02-15 Hayter Paul G Method for monitoring an implanted fluorescent light-emitting bead
US20070111196A1 (en) * 2005-08-19 2007-05-17 Javier Alarcon Sterilization of Biosensors
ATE555387T1 (de) * 2005-10-12 2012-05-15 Allergan Inc Tests der molekularen oder subzellulären nähe unter verwendung von depolarisierung nach resonanzenergietransfer (daret)
CA2625327A1 (en) * 2005-10-14 2007-04-19 Carnegie Institution Of Washington Phosphate biosensors and methods of using the same
AU2005337445A1 (en) * 2005-10-14 2007-04-26 Carnegie Institution Of Washington Sucrose biosensors and methods of using the same
EP1951110B1 (de) 2005-10-24 2012-10-03 Marcio Marc Aurelio Martins Abreu Vorrichtung zur messung biologischer parameter
AU2006315332A1 (en) * 2005-11-16 2007-05-24 Carnegie Institution Of Washington Multimeric biosensors and methods of using the same
US8158340B2 (en) 2005-12-28 2012-04-17 Corning Incorporated Methods for detecting conformational changes in bioentities
TW200734462A (en) 2006-03-08 2007-09-16 In Motion Invest Ltd Regulating stem cells
JP5337691B2 (ja) 2006-04-20 2013-11-06 ベクトン・ディキンソン・アンド・カンパニー 熱安定性タンパク質ならびにその作製方法および使用方法
US20090093758A1 (en) 2006-07-24 2009-04-09 Yossi Gross Fibroid treatment apparatus and method
JP5517919B2 (ja) 2007-05-10 2014-06-11 グルメトリクス、 インク． 即時血管内グルコース測定のための平衡非消費蛍光センサー
JP5453248B2 (ja) * 2007-05-22 2014-03-26 ベクトン・ディキンソン・アンド・カンパニー 代謝産物を検出するために比率測定蛍光応答を有する色素
WO2009021052A1 (en) * 2007-08-06 2009-02-12 University Of Kentucky Research Foundation Polypeptides, systems, and methods useful for detecting glucose
WO2009067626A1 (en) 2007-11-21 2009-05-28 Glumetrics, Inc. Use of an equilibrium intravascular sensor to achieve tight glycemic control
US20100160749A1 (en) * 2008-12-24 2010-06-24 Glusense Ltd. Implantable optical glucose sensing
EP2410908A1 (de) 2009-03-26 2012-02-01 The Arizona Board of Regents for and on behalf of Arizona State University Integrierte vorrichtung für oberflächenkontakt-probennahme und -extraktion sowie elektrochemische messungen
US8403953B2 (en) * 2009-07-27 2013-03-26 Fibro Control, Inc. Balloon with rigid tube for occluding the uterine artery
EP2483679A4 (de) * 2009-09-30 2013-04-24 Glumetrics Inc Sensoren mit thrombenresistenter beschichtung
US8741591B2 (en) 2009-10-09 2014-06-03 The Research Foundation For The State University Of New York pH-insensitive glucose indicator protein
US8467843B2 (en) 2009-11-04 2013-06-18 Glumetrics, Inc. Optical sensor configuration for ratiometric correction of blood glucose measurement
EP2545373B1 (de) * 2010-03-11 2022-08-24 Medtronic Minimed, Inc. Messung von analytkonzentrationen einschliesslich temperatur- und ph-korrektur
US20120130209A1 (en) * 2010-11-24 2012-05-24 Biotronik Se & Co. Kg Implantable Sensor Unit
SG193534A1 (en) 2011-03-23 2013-10-30 Agency Science Tech & Res Recombinant protein biosensors and a method for detecting the presence of an analyte molecule
US9037205B2 (en) 2011-06-30 2015-05-19 Glusense, Ltd Implantable optical glucose sensing
US9574057B2 (en) 2012-03-28 2017-02-21 Becton, Dickinson And Company Hydrogel adhesion to molded polymers
AU2013204332B2 (en) 2012-04-16 2015-07-16 Commonwealth Scientific And Industrial Research Organisation Methods and systems for detecting an analyte or classifying a sample
WO2014137993A1 (en) * 2013-03-04 2014-09-12 David Reed Markle METHODS FOR USE IN A CALIBRATION-FREE ABSORBANCE SENSOR FOR MEASURING pH AND pCO2
US20140350370A1 (en) * 2013-04-08 2014-11-27 The Texas A&M University System Glucose sensing assay
AU2014331655A1 (en) 2013-10-11 2016-05-26 Marcio Marc Abreu Method and apparatus for biological evaluation
JP2017501844A (ja) * 2014-01-10 2017-01-19 マーシオ マーク アブリュー Ａｂｒｅｕ脳熱トンネルの赤外線出力を測定するためのデバイス
JP2017505657A (ja) 2014-01-10 2017-02-23 マーシオ マーク アブリュー Ａｂｒｅｕ脳トンネルでモニタして治療を提供するデバイス
US10238847B2 (en) 2014-01-22 2019-03-26 Geelux Holdings, Ltd. Devices and methods for transdermal drug delivery
EP3189162A1 (de) * 2014-09-02 2017-07-12 Pharmozyme, Inc. Plattform zur genetischen detektion
WO2016054079A1 (en) 2014-09-29 2016-04-07 Zyomed Corp. Systems and methods for blood glucose and other analyte detection and measurement using collision computing
WO2016059635A1 (en) 2014-10-13 2016-04-21 Glusense Ltd. Analyte-sensing device
JP2018512915A (ja) 2015-03-10 2018-05-24 マーシオ マーク アブリュー Ａｂｔｔ終端の温度を測定するためのデバイス、装置、システム、及び方法
CA3005831A1 (en) * 2015-11-20 2017-05-26 Duke University Glucose biosensors and uses thereof
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
WO2017183030A1 (en) 2016-04-20 2017-10-26 Glusense Ltd. Fret-based glucose-detection molecules
AU2017358067B2 (en) 2016-11-14 2024-04-18 PPB Technology Pty Ltd Protease sensor molecules
CA3071994A1 (en) 2017-08-08 2019-02-14 Commonwealth Scientific And Industrial Research Organisation Carbohydrate sensors
WO2021081404A1 (en) 2019-10-25 2021-04-29 Cercacor Laboratories, Inc. Indicator compounds, devices comprising indicator compounds, and methods of making and using the same
USD1084670S1 (en) * 2022-06-16 2025-07-22 3M Innovative Properties Company Lint roller handle
JP2025523210A (ja) * 2022-07-18 2025-07-17 ウィロー・ラボラトリーズ・インコーポレイテッド 遺伝子操作されたグルコース結合タンパク質へのグルコース平衡結合による電気化学的グルコース感知

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681923A (en) * 1995-10-06 1997-10-28 Platt; David Tumor derived carbohydrate binding protein
AU6702398A (en) * 1997-03-14 1998-09-29 Regents Of The University Of California, The Fluorescent protein sensors for detection of analytes
EP1044374B1 (de) * 1997-12-31 2008-10-08 Duke University Glukosebiosensor

Also Published As

Publication number Publication date
AU759888B2 (en) 2003-05-01
US6197534B1 (en) 2001-03-06
CA2336985A1 (en) 2000-01-27
DE69941085D1 (de) 2009-08-20
EP1098658A1 (de) 2001-05-16
EP1098658A4 (de) 2008-01-02
AU5103399A (en) 2000-02-07
EP1098658B1 (de) 2009-07-08
WO2000003727A9 (en) 2000-07-20
DK1098658T3 (da) 2009-11-09
CA2336985C (en) 2011-01-04
ES2329850T3 (es) 2009-12-01
WO2000003727A1 (en) 2000-01-27

Similar Documents

Publication Publication Date Title
DE69941085D1 (de) Manipulierte proteine zum analyten nachweis
DE60118527D1 (de) Sensible und multiplexe diagnostische tests zur proteinanalyse
DE69840107D1 (de) Glukosebiosensor
WO2004101769A3 (en) Proteins, sensors, and methods of characterizing analytes using the same
PT1077634E (pt) Monitorizacao de substancias fisiologicas a analisar
WO2004070020A3 (en) Glyphosate tolerant alfalfa events and methods for detection thereof
WO2001042502A3 (en) Methods for disease detection
DK0645015T3 (da) Forbedringer ved eller i forbindelse med analytpåvisning.
TW200720441A (en) New labelling strategies for the sensitive detection of analytes
TR199901569T2 (xx) T�berk�lozun te�hisi i�in bile�ikler ve y�ntemler.
ATE325203T1 (de) Nachweis und identifikation von bakteriengruppen
TW200741203A (en) Detection of a target antigen irrespective of the presence or absence of a corresponding therapeutic antibody
ECSP056124A (es) Método y dispositivo para detectar analitos volátiles en muestras de aire
ATE229571T1 (de) Nachweis und identifizierung von nicht-polio enteroviren
DE50207801D1 (de) Verfahren zum Nachweis prokaryontischer DNA
EP0843019A3 (de) Verfahren zur Bestimmung einer spezifischen Nukleinsäuresequenz, und ein Reagenz für diesen Zweck
NO964084L (no) Påvisning av analytter
ATE259964T1 (de) Kompetitives assay-verfahren
WO2006071970A3 (en) Methods for the detection of analytes in a sample
WO2002077285A3 (en) Methods of determining the presence of polynucleotides employing amplification
WO2004016802A3 (en) Methods and apparatus for preparing and assaying biological samples to determine protein concentration
DE50203136D1 (de) Verfahren zum Nachweis von Analyten in Proben mittels Analysenelementen
SE0102896D0 (sv) System and method for blood analysis
WO2002014857A3 (en) Direct selection of protein complexes relevant to the physiological or diagnostic context of a biological specimen
DE69920981D1 (de) Knorpelresorptionsassays

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties