ATE437178T1 - Analgetisches antitumorpeptid aus skorpionen und verfahren zu dessen herstellung - Google Patents

Analgetisches antitumorpeptid aus skorpionen und verfahren zu dessen herstellung

Info

Publication number
ATE437178T1
ATE437178T1 AT02774251T AT02774251T ATE437178T1 AT E437178 T1 ATE437178 T1 AT E437178T1 AT 02774251 T AT02774251 T AT 02774251T AT 02774251 T AT02774251 T AT 02774251T AT E437178 T1 ATE437178 T1 AT E437178T1
Authority
AT
Austria
Prior art keywords
analgesic
peptide
scorpion
antitumor activity
scorpions
Prior art date
Application number
AT02774251T
Other languages
English (en)
Inventor
Jinghai Zhang
Runlin Ma
Siling Wang
Chunfu Wu
Yanfeng Liu
Original Assignee
Univ Shenyang Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Shenyang Pharmaceutical filed Critical Univ Shenyang Pharmaceutical
Application granted granted Critical
Publication of ATE437178T1 publication Critical patent/ATE437178T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43522—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from scorpions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Insects & Arthropods (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)
AT02774251T 2001-09-30 2002-09-29 Analgetisches antitumorpeptid aus skorpionen und verfahren zu dessen herstellung ATE437178T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNB011282355A CN1325514C (zh) 2001-09-30 2001-09-30 蝎镇痛抗肿瘤缬精甘肽及获得方法
PCT/CN2002/000699 WO2003037922A1 (en) 2001-09-30 2002-09-29 Analgesic antitumor peptide from scorpion and method of producing it

Publications (1)

Publication Number Publication Date
ATE437178T1 true ATE437178T1 (de) 2009-08-15

Family

ID=4668113

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02774251T ATE437178T1 (de) 2001-09-30 2002-09-29 Analgetisches antitumorpeptid aus skorpionen und verfahren zu dessen herstellung

Country Status (6)

Country Link
US (1) US7592309B2 (de)
EP (1) EP1443053B1 (de)
CN (1) CN1325514C (de)
AT (1) ATE437178T1 (de)
DE (1) DE60233064D1 (de)
WO (1) WO2003037922A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1325514C (zh) * 2001-09-30 2007-07-11 沈阳药科大学 蝎镇痛抗肿瘤缬精甘肽及获得方法
WO2009035417A1 (en) * 2007-09-13 2009-03-19 National University Of Singapore Neuroprotective agents
US8097284B2 (en) * 2007-11-13 2012-01-17 Arthur Mikaelian Polarized scorpion venom solution and a method for making polarized scorpion venom solution
CN101875691B (zh) * 2010-02-09 2014-04-02 沈阳药科大学 蝎镇痛抗肿瘤缬精甘肽突变体及其制备方法
CU24055B1 (es) * 2010-09-27 2014-12-26 Grupo Empresarial De Producciones Biofarmacéuticas Y Químicas Labiofam Composiciones farmacéuticas de veneno de escorpión rhopalurus junceus
CN102690342B (zh) * 2011-03-22 2014-10-29 沈阳药科大学 抗癌止痛肽vkvr及其制备方法与应用
CN104419694A (zh) * 2013-08-29 2015-03-18 江苏柯菲平医药股份有限公司 一种提高牛虻抗血栓酶kfpase生物活性的复性方法
CN104193813B (zh) * 2014-09-05 2017-01-25 四川省中医药科学院 一种蝎毒多肽的分离纯化方法及其用途
CN107043799A (zh) * 2017-03-14 2017-08-15 山东中医药大学 一种全蝎酶解液超滤物制备工艺及其用途
CN109157649A (zh) * 2017-06-08 2019-01-08 赵恩成 一种蝎肽的制药用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR970009203B1 (en) 1993-12-29 1997-06-07 Lg Metal Co Ltd Permanent magnet testing & selecting apparatus
CN1282657C (zh) * 2000-01-13 2006-11-01 南京大学 蝎抗神经兴奋肽
CN1325514C (zh) * 2001-09-30 2007-07-11 沈阳药科大学 蝎镇痛抗肿瘤缬精甘肽及获得方法

Also Published As

Publication number Publication date
US7592309B2 (en) 2009-09-22
CN1325514C (zh) 2007-07-11
US20060252676A1 (en) 2006-11-09
WO2003037922A1 (en) 2003-05-08
CN1341662A (zh) 2002-03-27
EP1443053A4 (de) 2005-12-07
EP1443053A1 (de) 2004-08-04
EP1443053B1 (de) 2009-07-22
DE60233064D1 (de) 2009-09-03

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