ATE437359T1 - Verwendung von temperatur- und strömungsprofilen bei analytischen prozessen auf gradientenelutionsbasis - Google Patents

Verwendung von temperatur- und strömungsprofilen bei analytischen prozessen auf gradientenelutionsbasis

Info

Publication number
ATE437359T1
ATE437359T1 AT03777995T AT03777995T ATE437359T1 AT E437359 T1 ATE437359 T1 AT E437359T1 AT 03777995 T AT03777995 T AT 03777995T AT 03777995 T AT03777995 T AT 03777995T AT E437359 T1 ATE437359 T1 AT E437359T1
Authority
AT
Austria
Prior art keywords
temperature
matrix
control device
interface
flow
Prior art date
Application number
AT03777995T
Other languages
English (en)
Inventor
Terry Sheehan
Original Assignee
Varian Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Varian Inc filed Critical Varian Inc
Application granted granted Critical
Publication of ATE437359T1 publication Critical patent/ATE437359T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G01N30/724—Nebulising, aerosol formation or ionisation
    • G01N30/7266—Nebulising, aerosol formation or ionisation by electric field, e.g. electrospray
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G01N30/7273—Desolvation chambers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT03777995T 2002-10-30 2003-10-29 Verwendung von temperatur- und strömungsprofilen bei analytischen prozessen auf gradientenelutionsbasis ATE437359T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42246502P 2002-10-30 2002-10-30
PCT/US2003/034442 WO2004042384A1 (en) 2002-10-30 2003-10-29 Use of temperature and flow profiles in gradient elution based analytical process

Publications (1)

Publication Number Publication Date
ATE437359T1 true ATE437359T1 (de) 2009-08-15

Family

ID=32312512

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03777995T ATE437359T1 (de) 2002-10-30 2003-10-29 Verwendung von temperatur- und strömungsprofilen bei analytischen prozessen auf gradientenelutionsbasis

Country Status (8)

Country Link
US (1) US7547555B2 (de)
EP (1) EP1561102B1 (de)
JP (1) JP4515265B2 (de)
AT (1) ATE437359T1 (de)
AU (1) AU2003286782A1 (de)
CA (1) CA2503069A1 (de)
DE (1) DE60328511D1 (de)
WO (1) WO2004042384A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2441472B (en) * 2005-06-24 2011-05-04 Waters Investments Ltd Mass spectrometer interface housing
WO2009029231A2 (en) 2007-08-24 2009-03-05 Millipore Corporation Method of detecting filter extractables in biopharmaceutical products by liquid chromatography-mass spectrometry
WO2009029232A1 (en) 2007-08-24 2009-03-05 Millipore Corporation System and method for diversion of a liquid chromatography eluant
CN102279236A (zh) * 2010-06-08 2011-12-14 江苏天瑞仪器股份有限公司 色谱质谱联用仪
WO2012031082A2 (en) * 2010-09-02 2012-03-08 University Of The Sciences In Philadelphia System and method for ionization of molecules for mass spectrometry and ion mobility spectrometry
US20140166875A1 (en) 2010-09-02 2014-06-19 Wayne State University Systems and methods for high throughput solvent assisted ionization inlet for mass spectrometry
US8853621B2 (en) * 2010-10-25 2014-10-07 Wayne State University Systems and methods extending the laserspray ionization mass spectrometry concept from atmospheric pressure to vacuum
US8410434B1 (en) * 2011-09-16 2013-04-02 Science & Engineering Services, Inc. Thermo-stabilized nano- and micro- flow LC/ESI-MS interface and a method thereof
US10287180B1 (en) * 2015-01-05 2019-05-14 Sutro Connect Inc. Water monitoring device with replaceable reagent cartridge
WO2018167933A1 (ja) 2017-03-16 2018-09-20 株式会社島津製作所 荷電粒子の供給制御方法及び装置
US11764049B2 (en) * 2020-04-14 2023-09-19 Waters Technologies Corporation Coaxial introduction of calibrant in a flow path with analyte to an ion source
US20230015697A1 (en) * 2021-07-13 2023-01-19 Citrix Systems, Inc. Application programming interface (api) authorization

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59135467U (ja) * 1983-02-28 1984-09-10 日本電子株式会社 液体クロマトグラフ質量分析装置
US4814612A (en) * 1983-08-30 1989-03-21 Research Corporation Method and means for vaporizing liquids for detection or analysis
US4958529A (en) * 1989-11-22 1990-09-25 Vestec Corporation Interface for coupling liquid chromatography to solid or gas phase detectors
JPH0712797A (ja) * 1993-06-24 1995-01-17 Hitachi Ltd 質量分析装置
JP3379510B2 (ja) * 1993-12-09 2003-02-24 株式会社日立製作所 液体クロマトグラフ結合型質量分析装置
JP3087548B2 (ja) * 1993-12-09 2000-09-11 株式会社日立製作所 液体クロマトグラフ結合型質量分析装置
US5412208A (en) * 1994-01-13 1995-05-02 Mds Health Group Limited Ion spray with intersecting flow
JPH0943202A (ja) * 1995-07-27 1997-02-14 Shimadzu Corp 液体クロマトグラフ質量分析装置
JPH1078421A (ja) * 1996-09-03 1998-03-24 Hitachi Ltd 液体クロマトグラフ質量分析計
JPH11326302A (ja) * 1998-05-13 1999-11-26 Shimadzu Corp 液体クロマトグラフ質量分析装置
JP2000055880A (ja) * 1998-08-06 2000-02-25 Shimadzu Corp 液体クロマトグラフ質量分析装置
JP4023056B2 (ja) * 1999-12-22 2007-12-19 株式会社島津製作所 液体クロマトグラフ質量分析計
US7069151B2 (en) * 2000-02-08 2006-06-27 Regents Of The University Of Michigan Mapping of differential display of proteins
US20020023878A1 (en) * 2000-05-23 2002-02-28 Nathan Collins High-throughput purification process
JP2002015697A (ja) * 2000-06-30 2002-01-18 Jeol Ltd エレクトロスプレー・イオン源
US6484560B1 (en) * 2000-11-07 2002-11-26 Agilent Technologies, Inc. In Situ concentration of an analyte
JP3422992B2 (ja) * 2001-07-23 2003-07-07 株式会社日立製作所 質量分析計

Also Published As

Publication number Publication date
US20070048187A1 (en) 2007-03-01
JP2006504972A (ja) 2006-02-09
EP1561102A1 (de) 2005-08-10
DE60328511D1 (de) 2009-09-03
WO2004042384A1 (en) 2004-05-21
AU2003286782A1 (en) 2004-06-07
EP1561102B1 (de) 2009-07-22
US7547555B2 (en) 2009-06-16
JP4515265B2 (ja) 2010-07-28
CA2503069A1 (en) 2004-05-21

Similar Documents

Publication Publication Date Title
ATE437359T1 (de) Verwendung von temperatur- und strömungsprofilen bei analytischen prozessen auf gradientenelutionsbasis
DE69622086D1 (de) Thermisches Dämmungssystem in analytischem Instrument
EP0707209A3 (de) Temperaturregelung in tragbarem analytischen Instrument
EP0492927B1 (de) Verfahren zum Steuern der Flüssigkeitsversorgung eines chromatographischen Detektors
US4948389A (en) Gas chromatograph having cyro blast coolings
US9759695B2 (en) Column oven and liquid chromatograph
EP3290916B1 (de) Vorrichtung und verfahren zur verbesserten probenvorbereitung für elementaranalysespektrometer
EP3059586A1 (de) Gaschromatograf-massenspektrometer
EP3367091A1 (de) Gaschromatograph
EP1205750A3 (de) Verfahren und System für die Gaschromatographie
US9625428B2 (en) Modulated flame gas flow rates in flame-based detectors
Gil et al. Vapor generation–atomic spectrometric techniques. Expanding frontiers through specific-species preconcentration. A review
JP6891772B2 (ja) マルチディメンジョナルガスクロマトグラフ
Brand et al. Automated simultaneous measurement of the δ13C and δ2H values of methane and the δ13C and δ18O values of carbon dioxide in flask air samples using a new multi cryo‐trap/gas chromatography/isotope ratio mass spectrometry system
EP2361384A1 (de) Gaschromatographofen
US8549894B2 (en) Gas chromatography with ambient pressure stability control
EP1891430A1 (de) Verfahren zur kühlung einer chromatographischen spalte
JP4701855B2 (ja) ガスクロマトグラフ質量分析装置
US5337619A (en) Radiant energy sample heating and temperature control
EP0959351A3 (de) Verfahren und Vorrichtung für die Einführung von grossen Proben in Kapillarsäulen für die Gaschromatographie
JP2014157139A (ja) 液体クロマトグラフ
US9360462B2 (en) Gas chromatograph mass spectrometer
JP2010160053A (ja) ガスクロマトグラフ及びガスクロマトグラフ分析方法
EP2315021B1 (de) Gaschromatographie mit Umgebungsdruckstabilitätsregelung
WO2019207850A1 (ja) クロマトグラフィー分析システム

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties