ATE439344T1 - Muscarin-antagonisten - Google Patents
Muscarin-antagonistenInfo
- Publication number
- ATE439344T1 ATE439344T1 AT01985584T AT01985584T ATE439344T1 AT E439344 T1 ATE439344 T1 AT E439344T1 AT 01985584 T AT01985584 T AT 01985584T AT 01985584 T AT01985584 T AT 01985584T AT E439344 T1 ATE439344 T1 AT E439344T1
- Authority
- AT
- Austria
- Prior art keywords
- muscarine antagonists
- muscarine
- antagonists
- Prior art date
Links
- UQOFGTXDASPNLL-XHNCKOQMSA-N Muscarine Chemical compound C[C@@H]1O[C@H](C[N+](C)(C)C)C[C@H]1O UQOFGTXDASPNLL-XHNCKOQMSA-N 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25785300P | 2000-12-22 | 2000-12-22 | |
| PCT/US2001/049063 WO2002051808A2 (en) | 2000-12-22 | 2001-12-17 | Muscarinic antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE439344T1 true ATE439344T1 (de) | 2009-08-15 |
Family
ID=22978046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01985584T ATE439344T1 (de) | 2000-12-22 | 2001-12-17 | Muscarin-antagonisten |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6458812B1 (de) |
| EP (1) | EP1343760B1 (de) |
| JP (2) | JP4012068B2 (de) |
| CN (1) | CN1481360A (de) |
| AR (1) | AR035612A1 (de) |
| AT (1) | ATE439344T1 (de) |
| AU (1) | AU2002235224A1 (de) |
| CA (1) | CA2431952C (de) |
| DE (1) | DE60139571D1 (de) |
| ES (1) | ES2329975T3 (de) |
| HK (1) | HK1054391A1 (de) |
| MX (1) | MXPA03005743A (de) |
| MY (1) | MY133992A (de) |
| PE (1) | PE20020657A1 (de) |
| WO (1) | WO2002051808A2 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7763609B2 (en) | 2003-12-15 | 2010-07-27 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
| US7700603B2 (en) * | 2003-12-15 | 2010-04-20 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
| US7592348B2 (en) * | 2003-12-15 | 2009-09-22 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
| US9132135B2 (en) * | 2004-09-24 | 2015-09-15 | University Of Maryland, Baltimore | Method of treating organophosphorous poisoning |
| EP2813225B1 (de) * | 2004-09-24 | 2017-12-13 | University of Maryland, Baltimore | Verfahren zur Behandlung von Organophosphorvergiftung |
| US7678116B2 (en) | 2004-12-06 | 2010-03-16 | Dfine, Inc. | Bone treatment systems and methods |
| US7559932B2 (en) * | 2004-12-06 | 2009-07-14 | Dfine, Inc. | Bone treatment systems and methods |
| US7722620B2 (en) | 2004-12-06 | 2010-05-25 | Dfine, Inc. | Bone treatment systems and methods |
| US7759353B2 (en) * | 2005-06-14 | 2010-07-20 | Schering Corporation | Substituted spiro iminopyrimidinones as aspartyl protease inhibitors, compositions, and methods of treatment |
| US8722708B2 (en) | 2005-06-14 | 2014-05-13 | Merck Sharp & Dohme Inc. | Substituted isoindolines as aspartyl protease inhibitors |
| ATE489370T1 (de) | 2005-06-14 | 2010-12-15 | Schering Corp | Herstellung und verwendung von verbindungen als aspartylproteasehemmer |
| WO2006138264A2 (en) | 2005-06-14 | 2006-12-28 | Schering Corporation | Aspartyl protease inhibitors |
| CA2609562A1 (en) * | 2005-06-14 | 2006-12-28 | Schering Corporation | Macrocyclic heterocyclic aspartyl protease inhibitors |
| US20080027456A1 (en) * | 2006-07-19 | 2008-01-31 | Csaba Truckai | Bone treatment systems and methods |
| US8696679B2 (en) | 2006-12-08 | 2014-04-15 | Dfine, Inc. | Bone treatment systems and methods |
| MX2009006228A (es) | 2006-12-12 | 2009-06-22 | Schering Corp | Inhibidores de aspartil proteasa. |
| CN101631779A (zh) * | 2006-12-12 | 2010-01-20 | 先灵公司 | 含有三环系统的天冬氨酰蛋白酶抑制剂 |
| WO2008137428A2 (en) | 2007-04-30 | 2008-11-13 | Dfine, Inc. | Bone treatment systems and methods |
| CN101848897A (zh) | 2007-09-06 | 2010-09-29 | 先灵公司 | γ分泌酶调节剂 |
| US8487099B2 (en) | 2007-11-05 | 2013-07-16 | Merck Sharp & Dohme Corp. | Gamma secretase modulators |
| WO2009076352A1 (en) * | 2007-12-11 | 2009-06-18 | Schering Corporation | Gamma secretase modulators |
| JP5503663B2 (ja) | 2008-11-13 | 2014-05-28 | メルク・シャープ・アンド・ドーム・コーポレーション | ガンマセクレターゼモジュレータ |
| EP2379566A2 (de) | 2008-12-22 | 2011-10-26 | Schering Corporation | Modulatoren von gamma-sekretase |
| AU2009330233A1 (en) | 2008-12-22 | 2011-07-07 | Merck Sharp & Dohme Corp. | Gamma secretase modulators |
| EP2412705B1 (de) * | 2009-03-26 | 2014-05-07 | Dainippon Sumitomo Pharma Co., Ltd. | Neues therapeutikum für kognitive beeinträchtigung |
| US20120245158A1 (en) | 2009-06-16 | 2012-09-27 | Xianhai Huang | Gamma secretase modulators |
| WO2010147969A2 (en) | 2009-06-16 | 2010-12-23 | Schering Corporation | Gamma secretase modulators |
| EP2443118A1 (de) | 2009-06-16 | 2012-04-25 | Schering Corporation | Gammasekretasemodulatoren |
| WO2011143457A2 (en) | 2010-05-12 | 2011-11-17 | Northwestern University | Compositions and methods for treating or preventing atrial fibrillation |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04312572A (ja) * | 1991-04-12 | 1992-11-04 | Takeda Chem Ind Ltd | 環状アミン化合物 |
| IL117149A0 (en) | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
| TW542822B (en) * | 1997-01-17 | 2003-07-21 | Ajinomoto Kk | Benzamidine derivatives |
| US6066636A (en) | 1998-06-30 | 2000-05-23 | Schering Corporation | Muscarinic antagonists |
-
2001
- 2001-12-17 AU AU2002235224A patent/AU2002235224A1/en not_active Abandoned
- 2001-12-17 US US10/023,277 patent/US6458812B1/en not_active Expired - Fee Related
- 2001-12-17 DE DE60139571T patent/DE60139571D1/de not_active Expired - Lifetime
- 2001-12-17 AR ARP010105838A patent/AR035612A1/es unknown
- 2001-12-17 CA CA002431952A patent/CA2431952C/en not_active Expired - Fee Related
- 2001-12-17 EP EP01985584A patent/EP1343760B1/de not_active Expired - Lifetime
- 2001-12-17 AT AT01985584T patent/ATE439344T1/de not_active IP Right Cessation
- 2001-12-17 JP JP2002552905A patent/JP4012068B2/ja not_active Expired - Fee Related
- 2001-12-17 WO PCT/US2001/049063 patent/WO2002051808A2/en not_active Ceased
- 2001-12-17 CN CNA018209718A patent/CN1481360A/zh active Pending
- 2001-12-17 HK HK03106691.6A patent/HK1054391A1/zh unknown
- 2001-12-17 MX MXPA03005743A patent/MXPA03005743A/es active IP Right Grant
- 2001-12-17 ES ES01985584T patent/ES2329975T3/es not_active Expired - Lifetime
- 2001-12-18 PE PE2001001266A patent/PE20020657A1/es not_active Application Discontinuation
- 2001-12-19 MY MYPI20015743A patent/MY133992A/en unknown
-
2007
- 2007-08-03 JP JP2007203608A patent/JP2007297410A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP4012068B2 (ja) | 2007-11-21 |
| CA2431952A1 (en) | 2002-07-04 |
| CA2431952C (en) | 2010-03-09 |
| JP2004516313A (ja) | 2004-06-03 |
| AU2002235224A1 (en) | 2002-07-08 |
| AR035612A1 (es) | 2004-06-16 |
| CN1481360A (zh) | 2004-03-10 |
| WO2002051808A3 (en) | 2003-01-23 |
| PE20020657A1 (es) | 2002-07-23 |
| MY133992A (en) | 2007-11-30 |
| WO2002051808A2 (en) | 2002-07-04 |
| HK1054391A1 (zh) | 2003-11-28 |
| EP1343760B1 (de) | 2009-08-12 |
| EP1343760A2 (de) | 2003-09-17 |
| DE60139571D1 (de) | 2009-09-24 |
| ES2329975T3 (es) | 2009-12-03 |
| JP2007297410A (ja) | 2007-11-15 |
| US6458812B1 (en) | 2002-10-01 |
| MXPA03005743A (es) | 2003-09-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |