ATE439367T1 - Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen - Google Patents

Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen

Info

Publication number
ATE439367T1
ATE439367T1 AT05739739T AT05739739T ATE439367T1 AT E439367 T1 ATE439367 T1 AT E439367T1 AT 05739739 T AT05739739 T AT 05739739T AT 05739739 T AT05739739 T AT 05739739T AT E439367 T1 ATE439367 T1 AT E439367T1
Authority
AT
Austria
Prior art keywords
treatment
microbial infections
ester bonded
macrolides
macrolides suitable
Prior art date
Application number
AT05739739T
Other languages
English (en)
Inventor
Sulejman Alihodzic
Stjepan Mutak
Drazen Pavlovic
Ivana Palej
Vlado Stimac
Samra Kapic
Adrijana Vinter
Skugor Maja Matanovic
Original Assignee
Glaxosmithkline Zagreb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Zagreb filed Critical Glaxosmithkline Zagreb
Application granted granted Critical
Publication of ATE439367T1 publication Critical patent/ATE439367T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT05739739T 2004-05-06 2005-05-02 Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen ATE439367T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56940204P 2004-05-06 2004-05-06
US58111804P 2004-06-18 2004-06-18
PCT/IB2005/001186 WO2005108412A1 (en) 2004-05-06 2005-05-02 Ester linked macrolides useful for the treatment of microbial infections

Publications (1)

Publication Number Publication Date
ATE439367T1 true ATE439367T1 (de) 2009-08-15

Family

ID=34967616

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05739739T ATE439367T1 (de) 2004-05-06 2005-05-02 Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen

Country Status (16)

Country Link
US (1) US20080255060A1 (de)
EP (1) EP1756135B1 (de)
JP (1) JP2007536371A (de)
AR (1) AR049269A1 (de)
AT (1) ATE439367T1 (de)
AU (1) AU2005240849B2 (de)
BR (1) BRPI0510328A (de)
CA (1) CA2566085A1 (de)
DE (1) DE602005015963D1 (de)
ES (1) ES2331739T3 (de)
IL (1) IL178876A0 (de)
MA (1) MA28640B1 (de)
MX (1) MXPA06012923A (de)
NO (1) NO20065662L (de)
RU (1) RU2006143051A (de)
WO (1) WO2005108412A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7601695B2 (en) 2003-03-10 2009-10-13 Optimer Pharmaceuticals, Inc. Antibacterial agents
JP2008540503A (ja) 2005-05-10 2008-11-20 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 細菌感染症の処置に有用なエーテル結合マクロライド
MX2009005977A (es) * 2006-12-05 2009-06-17 Pfizer Polimorfos de motilida.
AU2008316830B2 (en) 2007-10-25 2016-03-17 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
CN107854477A (zh) 2008-10-24 2018-03-30 森普拉制药公司 使用含三唑的大环内酯治疗抗性疾病的方法
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
US9480679B2 (en) 2009-09-10 2016-11-01 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
BR112012029586A2 (pt) * 2010-05-20 2016-08-02 Cempra Pharmaceuticals Inc processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos
KR20130120458A (ko) 2010-09-10 2013-11-04 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
WO2013148891A1 (en) 2012-03-27 2013-10-03 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
WO2014152326A1 (en) 2013-03-14 2014-09-25 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
AU2014233240B2 (en) 2013-03-15 2018-08-09 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0127349D0 (en) * 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides
GB0225384D0 (en) * 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds
GB0310979D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
EP1628989B1 (de) * 2003-05-13 2006-12-20 Glaxo Group Limited Neue 14- und 15-gliedrige ringverbindungen
GB0310984D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
JP2008540503A (ja) * 2005-05-10 2008-11-20 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 細菌感染症の処置に有用なエーテル結合マクロライド

Also Published As

Publication number Publication date
AU2005240849B2 (en) 2008-10-23
ES2331739T3 (es) 2010-01-14
MA28640B1 (fr) 2007-06-01
BRPI0510328A (pt) 2007-10-23
EP1756135A1 (de) 2007-02-28
MXPA06012923A (es) 2007-07-18
WO2005108412A1 (en) 2005-11-17
AU2005240849A1 (en) 2005-11-17
JP2007536371A (ja) 2007-12-13
EP1756135B1 (de) 2009-08-12
IL178876A0 (en) 2007-03-08
CA2566085A1 (en) 2005-11-17
AR049269A1 (es) 2006-07-12
RU2006143051A (ru) 2008-06-20
DE602005015963D1 (de) 2009-09-24
US20080255060A1 (en) 2008-10-16
NO20065662L (no) 2007-01-16

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