ATE439367T1 - Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen - Google Patents

Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen

Info

Publication number
ATE439367T1
ATE439367T1 AT05739739T AT05739739T ATE439367T1 AT E439367 T1 ATE439367 T1 AT E439367T1 AT 05739739 T AT05739739 T AT 05739739T AT 05739739 T AT05739739 T AT 05739739T AT E439367 T1 ATE439367 T1 AT E439367T1
Authority
AT
Austria
Prior art keywords
treatment
microbial infections
ester bonded
macrolides
macrolides suitable
Prior art date
Application number
AT05739739T
Other languages
English (en)
Inventor
Sulejman Alihodzic
Stjepan Mutak
Drazen Pavlovic
Ivana Palej
Vlado Stimac
Samra Kapic
Adrijana Vinter
Skugor Maja Matanovic
Original Assignee
Glaxosmithkline Zagreb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Zagreb filed Critical Glaxosmithkline Zagreb
Application granted granted Critical
Publication of ATE439367T1 publication Critical patent/ATE439367T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT05739739T 2004-05-06 2005-05-02 Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen ATE439367T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56940204P 2004-05-06 2004-05-06
US58111804P 2004-06-18 2004-06-18
PCT/IB2005/001186 WO2005108412A1 (en) 2004-05-06 2005-05-02 Ester linked macrolides useful for the treatment of microbial infections

Publications (1)

Publication Number Publication Date
ATE439367T1 true ATE439367T1 (de) 2009-08-15

Family

ID=34967616

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05739739T ATE439367T1 (de) 2004-05-06 2005-05-02 Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen

Country Status (16)

Country Link
US (1) US20080255060A1 (de)
EP (1) EP1756135B1 (de)
JP (1) JP2007536371A (de)
AR (1) AR049269A1 (de)
AT (1) ATE439367T1 (de)
AU (1) AU2005240849B2 (de)
BR (1) BRPI0510328A (de)
CA (1) CA2566085A1 (de)
DE (1) DE602005015963D1 (de)
ES (1) ES2331739T3 (de)
IL (1) IL178876A0 (de)
MA (1) MA28640B1 (de)
MX (1) MXPA06012923A (de)
NO (1) NO20065662L (de)
RU (1) RU2006143051A (de)
WO (1) WO2005108412A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1638549A4 (de) 2003-03-10 2011-06-15 Optimer Pharmaceuticals Inc Neue antibakterielle mittel
WO2006120541A1 (en) * 2005-05-10 2006-11-16 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Ether linked macrolides useful for the treatment of microbial infections
CA2670482C (en) * 2006-12-05 2011-10-11 Pfizer Inc. Motilide polymorphs
EP2214484A4 (de) 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc Verfahren zur herstellung von antibakteriellen makrolid-wirkstoffen
JP5711135B2 (ja) 2008-10-24 2015-04-30 センプラ ファーマシューティカルズ，インコーポレイテッド 胃腸疾患を治療するための方法
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
ES2608285T3 (es) 2009-09-10 2017-04-07 Cempra Pharmaceuticals, Inc. Procedimientos para el tratamiento de paludismo, tuberculosis y enfermedades por MAC
CN102917708B (zh) 2010-05-20 2015-11-25 森普拉制药公司 制备大环内酯和酮内酯及其中间体的方法
EP2613630A4 (de) 2010-09-10 2014-01-15 Cempra Pharmaceuticals Inc Wasserstoffbindung zur formung von fluorketoliden zur behandlung von krankheiten
NZ700182A (en) 2012-03-27 2017-02-24 Cempra Pharmaceuticals Inc Parenteral formulations for administering macrolide antibiotics
AU2014239959A1 (en) 2013-03-14 2015-10-01 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
CN105188712A (zh) 2013-03-15 2015-12-23 森普拉制药公司 用于制备大环内酯抗菌剂的收敛方法
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0127349D0 (en) * 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides
GB0225384D0 (en) * 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds
ES2278319T3 (es) * 2003-05-13 2007-08-01 Glaxo Group Limited Nuevos compuestos con 14 y 15 miembros en el anillo.
GB0310984D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310979D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
WO2006120541A1 (en) * 2005-05-10 2006-11-16 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Ether linked macrolides useful for the treatment of microbial infections

Also Published As

Publication number Publication date
EP1756135A1 (de) 2007-02-28
IL178876A0 (en) 2007-03-08
EP1756135B1 (de) 2009-08-12
ES2331739T3 (es) 2010-01-14
DE602005015963D1 (de) 2009-09-24
NO20065662L (no) 2007-01-16
CA2566085A1 (en) 2005-11-17
AR049269A1 (es) 2006-07-12
US20080255060A1 (en) 2008-10-16
AU2005240849A1 (en) 2005-11-17
MA28640B1 (fr) 2007-06-01
MXPA06012923A (es) 2007-07-18
RU2006143051A (ru) 2008-06-20
WO2005108412A1 (en) 2005-11-17
AU2005240849B2 (en) 2008-10-23
JP2007536371A (ja) 2007-12-13
BRPI0510328A (pt) 2007-10-23

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