ATE441431T1 - Behandlung von nicht-septischen patienten mit verbrennungen zweiten grades mittels verabreichung von aktiviertem protein c - Google Patents
Behandlung von nicht-septischen patienten mit verbrennungen zweiten grades mittels verabreichung von aktiviertem protein cInfo
- Publication number
- ATE441431T1 ATE441431T1 AT07804504T AT07804504T ATE441431T1 AT E441431 T1 ATE441431 T1 AT E441431T1 AT 07804504 T AT07804504 T AT 07804504T AT 07804504 T AT07804504 T AT 07804504T AT E441431 T1 ATE441431 T1 AT E441431T1
- Authority
- AT
- Austria
- Prior art keywords
- administration
- burns
- activated protein
- treatment
- degree burns
- Prior art date
Links
- 206010006802 Burns second degree Diseases 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 101800004937 Protein C Proteins 0.000 abstract 2
- 102100036546 Salivary acidic proline-rich phosphoprotein 1/2 Human genes 0.000 abstract 2
- 101800001700 Saposin-D Proteins 0.000 abstract 2
- 229960000856 protein c Drugs 0.000 abstract 2
- CPKVUHPKYQGHMW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;molecular iodine Chemical compound II.C=CN1CCCC1=O CPKVUHPKYQGHMW-UHFFFAOYSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 229920000153 Povidone-iodine Polymers 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 230000010100 anticoagulation Effects 0.000 abstract 1
- 239000003899 bactericide agent Substances 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 229940088598 enzyme Drugs 0.000 abstract 1
- 230000020764 fibrinolysis Effects 0.000 abstract 1
- 230000035876 healing Effects 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 230000008288 physiological mechanism Effects 0.000 abstract 1
- 229960001621 povidone-iodine Drugs 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/18—Iodine; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
- A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
- A61K31/79—Polymers of vinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4866—Protein C (3.4.21.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR20060100494A GR1005700B (el) | 2006-09-01 | 2006-09-01 | Τροπος αντιμετωπισης της 1ης φασης του εγκαυματοσσε μη σηπτικους ασθενεις με συνεχη ενδοφλεβια χορηγηση ενεργοποιημενης πρωτεινης-c για 48 ωρες με στοχο τη μειωση της τελικης εγκαυματικης βλαβης καιαυξηση της ταχυτητας επουλωσης κατα τα πρωτα επτα μετεγκαυματικα 24ωρα |
| PCT/GR2007/000043 WO2008026014A1 (en) | 2006-09-01 | 2007-09-03 | Management of non septic patients suffering from partial thickness burns during the first 48 postburn hours by administration of activated protein c |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE441431T1 true ATE441431T1 (de) | 2009-09-15 |
Family
ID=38683660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07804504T ATE441431T1 (de) | 2006-09-01 | 2007-09-03 | Behandlung von nicht-septischen patienten mit verbrennungen zweiten grades mittels verabreichung von aktiviertem protein c |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1957098B1 (de) |
| AT (1) | ATE441431T1 (de) |
| DE (1) | DE602007002266D1 (de) |
| GR (1) | GR1005700B (de) |
| WO (1) | WO2008026014A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2676422T3 (es) * | 2012-07-04 | 2018-07-19 | Zz Biotech Llc | Proteína C activada para su uso en el tratamiento de trastornos inflamatorios de la piel |
| PT3131572T (pt) | 2014-04-16 | 2021-09-24 | Zz Biotech Llc | Análogo de apc para utilização em cicatrização de feridas |
| ES2890675T3 (es) | 2014-04-16 | 2022-01-21 | Zz Biotech Llc | APC para uso en el tratamiento de cicatrices cutáneas anormales |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4401651A (en) * | 1979-04-18 | 1983-08-30 | Knutson Richard A | Wound-healing compositions containing povidone-iodine |
| US4301145A (en) * | 1980-07-28 | 1981-11-17 | Cestari Joseph E | Antiseptic skin cream |
| HUP0001237A3 (en) * | 1997-10-20 | 2002-01-28 | Lilly Co Eli | Methods for treating vascular disorders |
| AU2002302192B2 (en) * | 2001-06-13 | 2007-08-16 | Zz Biotech Llc | Treatment and composition for wound healing |
-
2006
- 2006-09-01 GR GR20060100494A patent/GR1005700B/el active IP Right Grant
-
2007
- 2007-09-03 AT AT07804504T patent/ATE441431T1/de not_active IP Right Cessation
- 2007-09-03 WO PCT/GR2007/000043 patent/WO2008026014A1/en not_active Ceased
- 2007-09-03 DE DE602007002266T patent/DE602007002266D1/de not_active Expired - Fee Related
- 2007-09-03 EP EP07804504A patent/EP1957098B1/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1957098A1 (de) | 2008-08-20 |
| WO2008026014A1 (en) | 2008-03-06 |
| GR1005700B (el) | 2007-10-22 |
| EP1957098B1 (de) | 2009-09-02 |
| DE602007002266D1 (de) | 2009-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |