ATE441712T1 - Die nukleotidsequenz ann bindende zink-finger domänen - Google Patents

Die nukleotidsequenz ann bindende zink-finger domänen

Info

Publication number
ATE441712T1
ATE441712T1 AT02724178T AT02724178T ATE441712T1 AT E441712 T1 ATE441712 T1 AT E441712T1 AT 02724178 T AT02724178 T AT 02724178T AT 02724178 T AT02724178 T AT 02724178T AT E441712 T1 ATE441712 T1 AT E441712T1
Authority
AT
Austria
Prior art keywords
zinc finger
nucleotide sequence
finger domain
binding zinc
polypeptides
Prior art date
Application number
AT02724178T
Other languages
English (en)
Inventor
Carlos Barbas
Birgit Dreier
Original Assignee
Novartis Pharma Gmbh
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh, Scripps Research Inst filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE441712T1 publication Critical patent/ATE441712T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT02724178T 2001-02-21 2002-02-21 Die nukleotidsequenz ann bindende zink-finger domänen ATE441712T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79110601A 2001-02-21 2001-02-21
PCT/EP2002/001862 WO2002066640A2 (en) 2001-02-21 2002-02-21 Zinc finger binding domains for nucleotide sequence ann

Publications (1)

Publication Number Publication Date
ATE441712T1 true ATE441712T1 (de) 2009-09-15

Family

ID=25152705

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02724178T ATE441712T1 (de) 2001-02-21 2002-02-21 Die nukleotidsequenz ann bindende zink-finger domänen

Country Status (9)

Country Link
EP (1) EP1364027B1 (de)
JP (3) JP4309133B2 (de)
AT (1) ATE441712T1 (de)
AU (1) AU2002254903B2 (de)
CA (1) CA2442293A1 (de)
DE (1) DE60233555D1 (de)
IL (1) IL157464A0 (de)
NZ (1) NZ527476A (de)
WO (1) WO2002066640A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7013219B2 (en) 1999-01-12 2006-03-14 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
US7070934B2 (en) 1999-01-12 2006-07-04 Sangamo Biosciences, Inc. Ligand-controlled regulation of endogenous gene expression
US6534261B1 (en) 1999-01-12 2003-03-18 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
US7329728B1 (en) 1999-10-25 2008-02-12 The Scripps Research Institute Ligand activated transcriptional regulator proteins
CA2435394C (en) 2001-01-22 2018-01-09 Sangamo Biosciences, Inc. Modified zinc finger binding proteins
AU2002225187A1 (en) 2001-01-22 2002-07-30 Sangamo Biosciences, Inc. Zinc finger polypeptides and their use
JP4309133B2 (ja) * 2001-02-21 2009-08-05 ノバルティス アクチエンゲゼルシャフト ヌクレオチド配列ａｎｎについての亜鉛フィンガー結合ドメイン
US7262054B2 (en) 2002-01-22 2007-08-28 Sangamo Biosciences, Inc. Zinc finger proteins for DNA binding and gene regulation in plants
US7361635B2 (en) 2002-08-29 2008-04-22 Sangamo Biosciences, Inc. Simultaneous modulation of multiple genes
MA36970A1 (fr) * 2011-10-11 2016-03-31 Aliophtha Ag Régulation de l'expression d'un récepteur par l'intermédiaire de l'administration de facteurs de transcription artificiels
JP7401432B2 (ja) 2017-12-01 2023-12-19 エンコーデッド セラピューティクス， インコーポレイテッド 操作されたｄｎａ結合タンパク質
WO2020243651A1 (en) 2019-05-29 2020-12-03 Encoded Therapeutics, Inc. Compositions and methods for selective gene regulation
JP7630116B2 (ja) 2020-01-16 2025-02-17 国立研究開発法人理化学研究所 変異型ｋｌｆタンパク質、及び誘導多能性幹細胞の製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0770129B1 (de) * 1994-01-18 2005-11-23 The Scripps Research Institute Derivate von zinkfingerproteinen und methoden
US6140081A (en) * 1998-10-16 2000-10-31 The Scripps Research Institute Zinc finger binding domains for GNN
JP4309133B2 (ja) * 2001-02-21 2009-08-05 ノバルティス アクチエンゲゼルシャフト ヌクレオチド配列ａｎｎについての亜鉛フィンガー結合ドメイン

Also Published As

Publication number Publication date
CA2442293A1 (en) 2002-08-29
JP2009148272A (ja) 2009-07-09
JP4309133B2 (ja) 2009-08-05
IL157464A0 (en) 2004-03-28
NZ527476A (en) 2006-06-30
WO2002066640A2 (en) 2002-08-29
AU2002254903C1 (en) 2002-09-04
EP1364027A2 (de) 2003-11-26
AU2002254903B2 (en) 2007-06-21
WO2002066640A3 (en) 2003-07-24
JP2004520054A (ja) 2004-07-08
DE60233555D1 (de) 2009-10-15
EP1364027B1 (de) 2009-09-02
JP2010159279A (ja) 2010-07-22

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Legal Events

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