ATE441725T1 - Multienzym-nachweisverfahren - Google Patents
Multienzym-nachweisverfahrenInfo
- Publication number
- ATE441725T1 ATE441725T1 AT99965243T AT99965243T ATE441725T1 AT E441725 T1 ATE441725 T1 AT E441725T1 AT 99965243 T AT99965243 T AT 99965243T AT 99965243 T AT99965243 T AT 99965243T AT E441725 T1 ATE441725 T1 AT E441725T1
- Authority
- AT
- Austria
- Prior art keywords
- enzyme
- activity
- present
- measuring
- endogenous
- Prior art date
Links
- 238000001514 detection method Methods 0.000 title abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 12
- 108090000790 Enzymes Proteins 0.000 abstract 12
- 230000015556 catabolic process Effects 0.000 abstract 2
- 238000006731 degradation reaction Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- 238000001952 enzyme assay Methods 0.000 abstract 1
- 238000011002 quantification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11235998P | 1998-12-15 | 1998-12-15 | |
| PCT/US1999/029550 WO2000036098A1 (en) | 1998-12-15 | 1999-12-14 | Multiple enzyme assays |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE441725T1 true ATE441725T1 (de) | 2009-09-15 |
Family
ID=22343485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99965243T ATE441725T1 (de) | 1998-12-15 | 1999-12-14 | Multienzym-nachweisverfahren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6586196B1 (de) |
| EP (1) | EP1151090B1 (de) |
| JP (1) | JP4668418B2 (de) |
| AT (1) | ATE441725T1 (de) |
| AU (1) | AU781255B2 (de) |
| CA (1) | CA2353872C (de) |
| DE (1) | DE69941367D1 (de) |
| WO (1) | WO2000036098A1 (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2474695A1 (en) | 2002-02-01 | 2003-08-14 | Promega Corporation | Bioluminescent protease assay |
| AU2004210982B2 (en) * | 2003-02-12 | 2008-12-18 | Promega Corporation | Methods and kits for dual enzymatic assays whereby light is quenched from luminescent reactions |
| US20050026151A1 (en) * | 2003-07-17 | 2005-02-03 | Voyta John C. | Simultaneous generation of multiple chemiluminescent signals on solid supports |
| US20070254320A1 (en) * | 2003-10-20 | 2007-11-01 | Alan Olstein | Method and Kit for Detecting Listeria Spp. |
| US7553632B2 (en) * | 2004-01-22 | 2009-06-30 | Promega Corporation | Luminogenic and nonluminogenic multiplex assay |
| US7416854B2 (en) | 2004-01-22 | 2008-08-26 | Promega Corporation | Luminogenic and nonluminogenic multiplex assay |
| EP2272973B1 (de) | 2005-05-31 | 2015-05-27 | Promega Corporation | Luminogene und fluorogene Verbindungen und Verfahren für den Nachweis von Molekülen oder Leiden |
| EP1935986B1 (de) | 2005-05-31 | 2014-04-16 | Promega Corporation | Luminogene und fluorogene Verbindungen und Verfahren für den Nachweis von Molekülen oder Leiden |
| US8227572B2 (en) * | 2005-08-19 | 2012-07-24 | Commonwealth Scientific And Industrial Research Organisation | Arachnocampa luciferases |
| EP1929308A1 (de) * | 2005-09-01 | 2008-06-11 | Promega Corporation | Luminogene und nichtluminogene proteasomentests auf zellbasis |
| JP2007225547A (ja) * | 2006-02-27 | 2007-09-06 | Fujifilm Corp | 標的物質の疎水部位の検出方法 |
| WO2008127677A2 (en) | 2007-04-13 | 2008-10-23 | Promega Corporation | Luminescent live and dead cell assay |
| WO2009137666A2 (en) * | 2008-05-08 | 2009-11-12 | The Trustees Of The University Of Pennsylvania | Chemiluminescence enhanced detection |
| CA2739936C (en) | 2008-10-17 | 2017-12-12 | Pharmacofore, Inc. | Pharmaceutical compositions with attenuated release of phenolic opioids |
| US9493477B2 (en) | 2009-09-08 | 2016-11-15 | Signature Therapeutics, Inc. | Compositions comprising enzyme-cleavable ketone-modified opioid prodrugs and optional inhibitors thereof |
| US20110097723A1 (en) * | 2009-09-19 | 2011-04-28 | Qun Liu | Methods and reagents for analyte detection |
| JP5905402B2 (ja) | 2010-03-11 | 2016-04-20 | プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ | シアノベンゾチアゾール化合物を使用する生物発光アッセイ |
| WO2011133150A1 (en) * | 2010-04-21 | 2011-10-27 | Pharmacofore, Inc. | Compositions comprising enzyme-cleavable prodrugs of active agents and inhibitors thereof |
| WO2011133348A1 (en) | 2010-04-21 | 2011-10-27 | Pharmacofore, Inc. | Compositions comprising enzyme-cleavable amphetamine prodrugs and inhibitors thereof |
| US20110262355A1 (en) | 2010-04-21 | 2011-10-27 | Jenkins Thomas E | Compositions comprising enzyme-cleavable opioid prodrugs and inhibitors thereof |
| CA2795222A1 (en) * | 2010-04-21 | 2011-10-27 | Signature Therapeutics, Inc. | Compositions comprising enzyme-cleavable opioid prodrugs and inhibitors thereof |
| US9238020B2 (en) | 2010-04-21 | 2016-01-19 | Signature Therapeutics, Inc. | Compositions comprising enzyme-cleavable phenol-modified tapentadol prodrug |
| WO2012096887A2 (en) | 2011-01-11 | 2012-07-19 | Signature Therapeutics, Inc. | Compositions comprising enzyme-cleavable oxycodone prodrug |
| US8497237B2 (en) | 2011-01-11 | 2013-07-30 | Signature Therapeutics, Inc. | Compositions comprising enzyme-cleavable oxycodone prodrug |
| AU2012225337B2 (en) | 2011-03-09 | 2016-04-28 | Signature Therapeutics, Inc. | Active agent prodrugs with heterocyclic linkers |
| WO2012122420A2 (en) | 2011-03-09 | 2012-09-13 | Pharmacofore, Inc. | Opioid prodrugs with heterocyclic linkers |
| WO2013138522A2 (en) | 2012-03-16 | 2013-09-19 | Genelux Corporation | Methods for assessing effectiveness and monitoring oncolytic virus treatment |
| WO2013158265A1 (en) | 2012-04-20 | 2013-10-24 | Genelux Corporation | Imaging methods for oncolytic virus therapy |
| EP2719703A1 (de) | 2012-10-12 | 2014-04-16 | Ecole Polytechnique Fédérale de Lausanne (EPFL) | Vorläufermolekül für die Synthese von D-Luciferin |
| JP7007862B2 (ja) * | 2017-10-31 | 2022-01-25 | アークレイ株式会社 | 化学発光試薬組成物及び化学発光試薬キット |
| MX2023010506A (es) | 2021-03-09 | 2023-09-20 | Ensysce Biosciences Inc | Composiciones que comprenden profarmacos de escision enzimatica y nafamostat de liberacion controlada y metodos de uso de estos. |
| CA3230025A1 (en) | 2021-09-29 | 2023-04-06 | Lynn Kirkpatrick | Enzyme-cleavable methadone prodrugs and methods of use thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4124388A (en) | 1977-05-02 | 1978-11-07 | Polaroid Corporation | Ammonium mordants for photographic dyes |
| US4322489A (en) | 1980-04-22 | 1982-03-30 | Polaroid Corporation | Copolymeric mordants and photographic products and processes utilizing same |
| US4424326A (en) | 1980-04-22 | 1984-01-03 | Polaroid Corporation | Copolymeric mordants |
| US4340522A (en) | 1980-04-22 | 1982-07-20 | Polaroid Corporation | Process for preparing cationic polymers |
| US4503138A (en) | 1983-09-01 | 1985-03-05 | Polaroid Corporation | Image-receiving element with unitary image-receiving and decolorizing layer |
| US4563411A (en) | 1984-08-17 | 1986-01-07 | Polaroid Corporation | Copolymeric mordants and photographic products and processes containing same |
| US5112960A (en) | 1989-07-17 | 1992-05-12 | Bronstein Irena Y | Chemiluminescent 3-(substituted adamant-2'-ylidene) 1,2-dioxetanes |
| US4931223A (en) * | 1986-07-24 | 1990-06-05 | Tropix, Inc. | Methods of using chemiluminescent 1,2-dioxetanes |
| US4978614A (en) | 1988-10-26 | 1990-12-18 | Tropix, Inc. | Method of detecting a substance using enzymatically-induced decomposition of dioxetanes |
| CA1340590C (en) | 1986-07-24 | 1999-06-08 | John C. Voyta | Chemiluminescence enhancement |
| US5538847A (en) | 1989-07-17 | 1996-07-23 | Tropix, Inc. | Chemiluminescent 1,2-dioxetanes |
| US5582980A (en) * | 1989-07-17 | 1996-12-10 | Tropix, Inc. | Chemiluminescent 1,2-dioxetanes |
| US5089630A (en) | 1987-12-31 | 1992-02-18 | Bronstein Irena Y | Dioxetanes for use in assays |
| DE69130668T2 (de) * | 1990-08-30 | 1999-05-20 | Tropix, Inc., Bedford, Mass. | Chemolumineszente 3-(substituierte adamant-2'-ylidene)1,2-dioxetane |
| US5744320A (en) * | 1995-06-07 | 1998-04-28 | Promega Corporation | Quenching reagents and assays for enzyme-mediated luminescence |
| US6602657B1 (en) * | 1995-12-28 | 2003-08-05 | Tropix, Inc. | Multiple reporter gene assay |
-
1999
- 1999-12-14 CA CA2353872A patent/CA2353872C/en not_active Expired - Fee Related
- 1999-12-14 DE DE69941367T patent/DE69941367D1/de not_active Expired - Lifetime
- 1999-12-14 JP JP2000588347A patent/JP4668418B2/ja not_active Expired - Fee Related
- 1999-12-14 AT AT99965243T patent/ATE441725T1/de not_active IP Right Cessation
- 1999-12-14 AU AU31201/00A patent/AU781255B2/en not_active Ceased
- 1999-12-14 WO PCT/US1999/029550 patent/WO2000036098A1/en not_active Ceased
- 1999-12-14 EP EP99965243A patent/EP1151090B1/de not_active Expired - Lifetime
- 1999-12-14 US US09/459,982 patent/US6586196B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2353872C (en) | 2011-05-03 |
| EP1151090A4 (de) | 2007-05-02 |
| WO2000036098A1 (en) | 2000-06-22 |
| CA2353872A1 (en) | 2000-06-22 |
| US6586196B1 (en) | 2003-07-01 |
| AU3120100A (en) | 2000-07-03 |
| EP1151090A1 (de) | 2001-11-07 |
| JP2003520017A (ja) | 2003-07-02 |
| JP4668418B2 (ja) | 2011-04-13 |
| DE69941367D1 (de) | 2009-10-15 |
| EP1151090B1 (de) | 2009-09-02 |
| WO2000036098B1 (en) | 2000-07-27 |
| AU781255B2 (en) | 2005-05-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |