ATE442079T1 - Verfahren zum nicht invasiven messen von karotenoiden und verwandten chemischen substanzen in biologischem gewebe - Google Patents
Verfahren zum nicht invasiven messen von karotenoiden und verwandten chemischen substanzen in biologischem gewebeInfo
- Publication number
- ATE442079T1 ATE442079T1 AT00918311T AT00918311T ATE442079T1 AT E442079 T1 ATE442079 T1 AT E442079T1 AT 00918311 T AT00918311 T AT 00918311T AT 00918311 T AT00918311 T AT 00918311T AT E442079 T1 ATE442079 T1 AT E442079T1
- Authority
- AT
- Austria
- Prior art keywords
- carotenoids
- levels
- diagnostic information
- tissue
- raman signal
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 6
- 239000000126 substance Substances 0.000 title abstract 2
- 235000021466 carotenoid Nutrition 0.000 abstract 5
- 150000001747 carotenoids Chemical class 0.000 abstract 5
- 238000001069 Raman spectroscopy Methods 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000003550 marker Substances 0.000 abstract 1
- 238000001945 resonance Rayleigh scattering spectroscopy Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
- A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
- A61B5/443—Evaluating skin constituents, e.g. elastin, melanin, water
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N2021/653—Coherent methods [CARS]
- G01N2021/656—Raman microprobe
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Optics & Photonics (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Dermatology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/335,932 US6205354B1 (en) | 1999-06-18 | 1999-06-18 | Method and apparatus for noninvasive measurement of carotenoids and related chemical substances in biological tissue |
| PCT/US2000/007745 WO2000078217A1 (en) | 1999-06-18 | 2000-03-22 | Method and apparatus for noninvasive measurement of carotenoids and related chemical substances in biological tissue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE442079T1 true ATE442079T1 (de) | 2009-09-15 |
Family
ID=23313845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00918311T ATE442079T1 (de) | 1999-06-18 | 2000-03-22 | Verfahren zum nicht invasiven messen von karotenoiden und verwandten chemischen substanzen in biologischem gewebe |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6205354B1 (de) |
| EP (1) | EP1196088B1 (de) |
| JP (2) | JP3786873B2 (de) |
| KR (3) | KR100845640B1 (de) |
| AT (1) | ATE442079T1 (de) |
| AU (1) | AU3914400A (de) |
| CA (1) | CA2371886C (de) |
| DE (1) | DE60042931D1 (de) |
| WO (1) | WO2000078217A1 (de) |
Families Citing this family (138)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6389306B1 (en) * | 1998-04-24 | 2002-05-14 | Lightouch Medical, Inc. | Method for determining lipid and protein content of tissue |
| US7398119B2 (en) * | 1998-07-13 | 2008-07-08 | Childrens Hospital Los Angeles | Assessing blood brain barrier dynamics or identifying or measuring selected substances, including ethanol or toxins, in a subject by analyzing Raman spectrum signals |
| TWI220926B (en) * | 2000-03-24 | 2004-09-11 | Ind Tech Res Inst | Sieving apparatus for a bio-chip |
| GB2361994B (en) * | 2000-05-06 | 2004-12-08 | Astron Clinica Ltd | Apparatus and methods for analysing skin histology |
| US6473174B1 (en) * | 2000-09-01 | 2002-10-29 | Advanced Micro Devices, Inc. | Resist removal monitoring by raman spectroscopy |
| US6961599B2 (en) * | 2001-01-09 | 2005-11-01 | Childrens Hospital Los Angeles | Identifying or measuring selected substances or toxins in a subject using resonant raman signals |
| AU2002257083A1 (en) * | 2001-03-22 | 2002-10-08 | University Of Utah | Optical method and apparatus for determining status of agricultural products |
| US6954667B2 (en) * | 2001-06-28 | 2005-10-11 | Chemimage Corporation | Method for Raman chemical imaging and characterization of calcification in tissue |
| US8078268B2 (en) | 2001-06-28 | 2011-12-13 | Chemimage Corporation | System and method of chemical imaging using pulsed laser excitation and time-gated detection to determine tissue margins during surgery |
| US7596404B2 (en) * | 2001-06-28 | 2009-09-29 | Chemimage Corporation | Method of chemical imaging to determine tissue margins during surgery |
| US20030018271A1 (en) * | 2001-07-02 | 2003-01-23 | Kimble Allan Wayne | Simplified and lightweight system for enhanced visualization of subcutaneous hemoglobin-containing structures |
| US7039452B2 (en) * | 2002-12-19 | 2006-05-02 | The University Of Utah Research Foundation | Method and apparatus for Raman imaging of macular pigments |
| AU2002236343A1 (en) | 2002-02-28 | 2003-09-09 | Erasmus Universiteit Rotterdam | Depth selective ph measurement and uv exposure measurement |
| FR2840686B1 (fr) * | 2002-06-10 | 2008-11-14 | Oreal | Procede pour determiner l'aptitude a diffuser et/ou a absorber la lumiere d'un produit cosmetique |
| AU2003255248A1 (en) * | 2002-08-09 | 2004-02-25 | Emerge Interactive, Inc. | Real-time monitoring of factors relating to transmissible spongiform encephalopathies |
| US7593763B2 (en) * | 2003-02-05 | 2009-09-22 | Childrens Hospital Los Angeles | Non-invasive in vivo measurement of macular carotenoids |
| US7192783B2 (en) * | 2003-02-05 | 2007-03-20 | Research Foundation Of The City University Of New York | Stokes shift emission spectroscopy for detection of disease and physiological state of specimen |
| US20040254479A1 (en) | 2003-02-20 | 2004-12-16 | John Fralick | Bio-photonic feedback control software and database |
| JP2006527018A (ja) * | 2003-06-06 | 2006-11-30 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 血液のpH特定のための装置および方法 |
| CN1890557A (zh) * | 2003-11-28 | 2007-01-03 | Bc肿瘤研究所 | 根据拉曼和背景荧光谱多峰检测组织异常 |
| EP1697726A1 (de) * | 2003-12-16 | 2006-09-06 | Koninklijke Philips Electronics N.V. | Verfahren und vorrichtung zur optischen spektroskopie |
| KR100686659B1 (ko) * | 2004-02-19 | 2007-02-27 | 너스킨 인터어내셔날 인코포레이팃드 | 바이오 광 피드백 제어 장치 및 방법 |
| US20050278184A1 (en) | 2004-06-10 | 2005-12-15 | John Fralick | Bio-photonic feedback control software and database |
| US20050197581A1 (en) | 2004-02-19 | 2005-09-08 | Scott Ferguson | Bio-photonic-scanning calibration method |
| US7445600B1 (en) | 2004-03-01 | 2008-11-04 | Futrex, Inc. | Multi-function, self-service health kiosk |
| AU2004201242B2 (en) * | 2004-03-26 | 2010-10-28 | Nuskin International Inc | Bio-photonic feedback control software |
| US7697576B2 (en) * | 2004-05-05 | 2010-04-13 | Chem Image Corporation | Cytological analysis by raman spectroscopic imaging |
| US20060281068A1 (en) * | 2005-06-09 | 2006-12-14 | Chemimage Corp. | Cytological methods for detecting a disease condition such as malignancy by Raman spectroscopic imaging |
| US7403281B2 (en) * | 2004-05-07 | 2008-07-22 | University Of Wyoming | Raman spectrometer |
| US20120252050A1 (en) | 2004-06-22 | 2012-10-04 | Crescent Diagnostics Limited | Methods for assessing risk of bone fracture |
| US8535238B2 (en) | 2004-06-22 | 2013-09-17 | Crescent Diagnostics (Ireland) Limited | Diagnostic methods for osteoporosis |
| US7564546B2 (en) * | 2004-06-30 | 2009-07-21 | Chemimage Corporation | Dynamic imaging of biological cells and other subjects |
| US20060063991A1 (en) * | 2004-08-09 | 2006-03-23 | Dejin Yu | Method and apparatus for non-invasive measurement of blood analytes with dynamic spectral calibration |
| US20060063992A1 (en) * | 2004-08-09 | 2006-03-23 | Dejin Yu | Method and apparatus for non-invasive measurement of blood analytes |
| US7145651B2 (en) * | 2004-09-17 | 2006-12-05 | B & W Property Inc. | Apparatus for fluorescence subtracted Raman spectroscopy |
| CN1762303B (zh) * | 2004-10-22 | 2010-09-01 | 如新国际公司 | 生物光电反馈控制方法和装置 |
| US7365839B2 (en) * | 2004-11-03 | 2008-04-29 | Nu Skin International, Inc. | Process and compositions for synthetic calibration of bio-photonic scanners |
| EP1828731A1 (de) * | 2004-12-15 | 2007-09-05 | Koninklijke Philips Electronics N.V. | Kalibrierung einer optischen analyse durch verwendung multivariater optischer elemente |
| US20060244913A1 (en) * | 2004-12-21 | 2006-11-02 | Werner Gellermann | Imaging of macular pigment distributions |
| US20060134004A1 (en) * | 2004-12-21 | 2006-06-22 | The University Of Utah | Methods and apparatus for detection of carotenoids in macular tissue |
| US20060211926A1 (en) * | 2005-03-21 | 2006-09-21 | Dejin Yu | Non-invasive Raman measurement apparatus with broadband spectral correction |
| WO2006130921A1 (en) * | 2005-06-08 | 2006-12-14 | Monash University | Investigating biological cells using enhanced raman spectroscopy |
| US8253936B2 (en) * | 2008-08-08 | 2012-08-28 | Chemimage Corporation | Raman characterization of transplant tissue |
| US7558619B2 (en) * | 2005-10-04 | 2009-07-07 | Nu Skin International, Inc. | Raman instrument for measuring weak signals in the presence of strong background fluorescence |
| WO2007050602A2 (en) * | 2005-10-24 | 2007-05-03 | Chemimage Corporation | Automated acquisition of spectral data and image data |
| US20070166354A1 (en) | 2005-10-26 | 2007-07-19 | Bridget Barrett-Reis | Method of reducing the risk of retinopathy of prematurity in preterm infants |
| KR100862637B1 (ko) | 2006-05-30 | 2008-10-09 | (주) 인텍플러스 | 광학식 검사 방법 |
| JP2008043396A (ja) * | 2006-08-11 | 2008-02-28 | Olympus Corp | 内視鏡システム |
| JP2008148791A (ja) * | 2006-12-14 | 2008-07-03 | Olympus Corp | 内視鏡システム |
| US8652040B2 (en) | 2006-12-19 | 2014-02-18 | Valencell, Inc. | Telemetric apparatus for health and environmental monitoring |
| US8157730B2 (en) | 2006-12-19 | 2012-04-17 | Valencell, Inc. | Physiological and environmental monitoring systems and methods |
| BRPI0816925B8 (pt) | 2007-09-13 | 2021-06-22 | Univ Missouri | funil de luz de iluminação, funil de captação de luz e aparelho |
| US20100305436A1 (en) * | 2007-09-14 | 2010-12-02 | Light Sciences Oncology , Inc. | Systems, devices, and methods for photoactive assisted resection |
| SE531527C2 (sv) * | 2007-10-01 | 2009-05-12 | Bioresonator Ab | Förfarande vid och en anordning för opåverkad materialundersökning |
| CN101815925B (zh) * | 2007-10-02 | 2011-08-24 | 英泰克普拉斯有限公司 | 光学检验方法 |
| WO2009045492A1 (en) * | 2007-10-04 | 2009-04-09 | The Curators Of The University Of Missouri | Optical device components |
| US7961305B2 (en) * | 2007-10-23 | 2011-06-14 | The Curators Of The University Of Missouri | Optical device components |
| US8251903B2 (en) | 2007-10-25 | 2012-08-28 | Valencell, Inc. | Noninvasive physiological analysis using excitation-sensor modules and related devices and methods |
| JP2011516118A (ja) | 2008-03-25 | 2011-05-26 | ザ・キュレイターズ・オブ・ザ・ユニバーシティ・オブ・ミズーリ | グルコース以外の1つ以上の成分のスペクトルデータを使用して非侵襲で血糖を検出するための方法およびシステム |
| US7914147B2 (en) * | 2008-03-26 | 2011-03-29 | Image Technologies Corporation | Systems and methods for optical detection of lipofuscin concentrations in a subject's eye |
| WO2009135081A2 (en) * | 2008-04-30 | 2009-11-05 | Board Of Regents, The University Of Texas System | Integrated patient bed system |
| WO2010042253A2 (en) * | 2008-04-30 | 2010-04-15 | Board Of Regents, The University Of Texas System | An apparatus and method for noninvasive evalution of a target versus a non- target |
| EP2274051A4 (de) * | 2008-05-09 | 2011-07-20 | Hugh Beckman | Medizinisches gerät zur diagnostizierung und behandlung von gewebeanomalien und verfahren dafür |
| CA2724973C (en) | 2008-05-20 | 2015-08-11 | University Health Network | Device and method for fluorescence-based imaging and monitoring |
| CN102988061B (zh) | 2008-05-22 | 2015-04-01 | 密苏里大学董事会 | 用光谱数据分析进行无创的光学血糖检测的方法和系统 |
| US8260402B2 (en) * | 2008-06-06 | 2012-09-04 | Longevity Link, Inc. | Noninvasive measurement of carotenoids in biological tissue |
| US8416405B2 (en) * | 2008-08-08 | 2013-04-09 | Chemimage Corporation | Raman chemical imaging of implantable drug delivery devices |
| US9814417B2 (en) * | 2009-01-13 | 2017-11-14 | Longevity Link Corporation | Noninvasive measurement of flavonoid compounds in biological tissue |
| DE102009007398A1 (de) | 2009-01-30 | 2010-08-05 | Laser- und Medizin-Technologie GmbH, Berlin (LMTB) | Korrektur von Raman- oder Fluoreszenzmessungen bezüglich des Einflusses der optischen Eigenschaften des untersuchten Mediums |
| EP3357419A1 (de) | 2009-02-25 | 2018-08-08 | Valencell, Inc. | Lichtgeleitete vorrichtungen und überwachungsvorrichtungen damit |
| US8788002B2 (en) | 2009-02-25 | 2014-07-22 | Valencell, Inc. | Light-guiding devices and monitoring devices incorporating same |
| US9750462B2 (en) | 2009-02-25 | 2017-09-05 | Valencell, Inc. | Monitoring apparatus and methods for measuring physiological and/or environmental conditions |
| AU2010232841B2 (en) * | 2009-04-01 | 2014-04-24 | St. Louis Medical Devices, Inc. | Optical spectroscopy device for non-invasive blood glucose detection and associated method of use |
| US20110147615A1 (en) * | 2009-12-23 | 2011-06-23 | Kintz Gregory J | Method and apparatus for microscopic imaging system with wide field of view and high collection efficiency |
| US8665433B2 (en) * | 2010-08-17 | 2014-03-04 | Exelis Inc. | Standoff explosives detector using deep-UV Raman spectroscopy |
| US8888701B2 (en) | 2011-01-27 | 2014-11-18 | Valencell, Inc. | Apparatus and methods for monitoring physiological data during environmental interference |
| RO126898B1 (ro) | 2011-02-08 | 2016-05-30 | Staden Raluca Ioana Van | Sistem de scanare pentru analize biomedicale |
| WO2013016007A2 (en) | 2011-07-25 | 2013-01-31 | Valencell, Inc. | Apparatus and methods for estimating time-state physiological parameters |
| EP2739207B1 (de) | 2011-08-02 | 2017-07-19 | Valencell, Inc. | Systeme und verfahren für variable filtereinstellung durch ein herzrhythmus-messungsfeedback |
| JP2014520575A (ja) * | 2011-08-22 | 2014-08-25 | スペクトラル プラットフォームズ, インコーポレイテッド | 代謝活性の迅速検出 |
| BR112014018084A8 (pt) * | 2012-01-27 | 2017-07-11 | Koninklijke Philips Nv | Aparelho para a análise óptica de um tecido associado, método para a análise óptica de um tecido associado e produto de programa de computador |
| US9155473B2 (en) * | 2012-03-21 | 2015-10-13 | Korea Electrotechnology Research Institute | Reflection detection type measurement apparatus for skin autofluorescence |
| US20140058224A1 (en) * | 2012-08-21 | 2014-02-27 | Opticks, Inc. | Systems and methods for detection of carotenoid-related compounds in biological tissue |
| US20140104597A1 (en) * | 2012-10-12 | 2014-04-17 | Hamilton Sundstrand Space Systems International, Inc. | Dual-spectroscopy detection apparatus and method |
| US20140200419A1 (en) * | 2013-01-17 | 2014-07-17 | Igor V. Ermakov | Optical detection of carotenoid-related compounds in human bone and surrounding tissues |
| WO2014116942A2 (en) | 2013-01-28 | 2014-07-31 | Valencell, Inc. | Physiological monitoring devices having sensing elements decoupled from body motion |
| US20150201840A1 (en) * | 2013-03-18 | 2015-07-23 | Korea Electrotechnology Research Institute | Reflection detection type measurement apparatus for skin autofluorescence |
| US9888855B2 (en) * | 2013-03-18 | 2018-02-13 | Korea Electrotechnology Research Institute | Reflection detection type measurement apparatus and method for skin autofluorescence |
| JP6288936B2 (ja) * | 2013-04-22 | 2018-03-07 | ローム株式会社 | 癌診断装置 |
| WO2014175223A1 (ja) | 2013-04-22 | 2014-10-30 | ローム株式会社 | 癌診断装置、診断システム、診断装置 |
| CN103267746B (zh) * | 2013-04-23 | 2016-01-20 | 武汉新瑞达激光工程有限责任公司 | 一种宏观与微区集成式激光探针成分分析仪 |
| CN103398999B (zh) * | 2013-08-08 | 2015-11-04 | 浙江大学 | 基于拉曼光谱技术的等鞭金藻中胡萝卜素分布的检测方法 |
| KR101594523B1 (ko) | 2013-09-02 | 2016-02-16 | 한국광기술원 | 가시광 광학영상 및 비가시광 형광영상의 동시구현이 가능한 광대역 영상 획득투사장치 |
| CN103499560B (zh) * | 2013-09-29 | 2015-08-05 | 浙江大学 | 一种结合拉曼光谱技术和谱峰比值法的藻种鉴别方法 |
| CN104749156B (zh) * | 2013-12-27 | 2017-08-29 | 同方威视技术股份有限公司 | 拉曼光谱检测方法 |
| US10416079B2 (en) | 2014-01-07 | 2019-09-17 | Opsolution Gmbh | Device and method for determining a concentration in a sample |
| WO2015195975A1 (en) * | 2014-06-18 | 2015-12-23 | The Regents Of The University Of California | Raman imaging systems and methods |
| WO2016011534A1 (en) | 2014-07-24 | 2016-01-28 | University Health Network | Collection and analysis of data for diagnostic purposes |
| US20160029898A1 (en) | 2014-07-30 | 2016-02-04 | Valencell, Inc. | Physiological Monitoring Devices and Methods Using Optical Sensors |
| US10536768B2 (en) | 2014-08-06 | 2020-01-14 | Valencell, Inc. | Optical physiological sensor modules with reduced signal noise |
| US9794653B2 (en) | 2014-09-27 | 2017-10-17 | Valencell, Inc. | Methods and apparatus for improving signal quality in wearable biometric monitoring devices |
| EP3265863B1 (de) | 2015-02-13 | 2021-12-08 | The Regents of The University of California | Abtastverfahren zur gleichmässigen senkrechteinfall-bildgebung von sphärischen oberflächen mit einem einzelnen strahl |
| CN104749162B (zh) * | 2015-04-17 | 2018-03-27 | 江苏天瑞仪器股份有限公司 | 共聚焦拉曼光谱仪及其光路装置 |
| KR102396249B1 (ko) * | 2015-10-14 | 2022-05-09 | 삼성전자주식회사 | 라만 스펙트럼을 이용한 사용자 인증 장치 및 방법 |
| US10945618B2 (en) | 2015-10-23 | 2021-03-16 | Valencell, Inc. | Physiological monitoring devices and methods for noise reduction in physiological signals based on subject activity type |
| US10610158B2 (en) | 2015-10-23 | 2020-04-07 | Valencell, Inc. | Physiological monitoring devices and methods that identify subject activity type |
| US20170281077A1 (en) * | 2016-04-04 | 2017-10-05 | Speclipse, Inc. | System with disease diagnosis and skin age measurement functions and handpiece used therewith |
| KR101640202B1 (ko) * | 2016-04-04 | 2016-07-21 | 스페클립스 주식회사 | 레이저 조사 장치를 이용한 질병 진단 장치 및 질병 진단용 탈부착 핸드피스 |
| US10939844B2 (en) | 2016-04-15 | 2021-03-09 | The Regents Of The University Of California | THz sensing of corneal tissue water content |
| WO2017181200A1 (en) | 2016-04-15 | 2017-10-19 | The Regents Of The University Of California | Assessment of wound status and tissue viability via analysis of spatially resolved thz reflectometry maps |
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| LU93098B1 (de) * | 2016-06-03 | 2018-01-22 | Leica Microsystems | Verfahren zum Einstellen der Intensität eines Lichtstrahls in einer optischen Anordnung und zugehörige optische Anordnung |
| WO2017218821A1 (en) * | 2016-06-16 | 2017-12-21 | Valisure Llc | Methods and systems for spectroscopic analysis |
| US10966662B2 (en) | 2016-07-08 | 2021-04-06 | Valencell, Inc. | Motion-dependent averaging for physiological metric estimating systems and methods |
| CN106290292B (zh) * | 2016-07-25 | 2018-12-28 | 浙江大学 | 一种利用共聚焦显微拉曼检测茶叶中类胡萝卜素含量的方法 |
| EP3544492B1 (de) * | 2016-11-23 | 2025-01-01 | General Electric Company | Bildgebungsprotokollmanager |
| JP2020139735A (ja) * | 2017-06-26 | 2020-09-03 | 株式会社ニコン | 測定方法、測定装置 |
| KR102544670B1 (ko) | 2018-07-27 | 2023-06-16 | 삼성전자주식회사 | 항산화 센서, 항산화 신호 측정 방법 및 항산화 레벨 판단 방법 |
| US11555742B2 (en) | 2018-09-04 | 2023-01-17 | Provincial Health Services Authority | Image guided micro-Raman spectroscopy |
| CN109481851A (zh) * | 2018-09-14 | 2019-03-19 | 合肥泓博医学科技有限公司 | 一种咽喉护理器 |
| KR102375159B1 (ko) | 2019-03-22 | 2022-03-16 | 스페클립스 주식회사 | 레이저 유도 붕괴 스펙트럼 분석을 이용하는 진단 방법 및 이를 수행하는 진단 장치 |
| KR102914473B1 (ko) | 2019-08-20 | 2026-01-16 | 삼성전자주식회사 | 생체정보 추정 장치 및 방법 |
| KR102895685B1 (ko) | 2019-10-22 | 2025-12-03 | 삼성전자주식회사 | 항산화 센서 및 항산화 수치 측정 방법 |
| CN110910506B (zh) * | 2019-12-03 | 2021-02-09 | 江苏集萃华科智能装备科技有限公司 | 基于法线检测的三维重建方法、装置、检测装置及系统 |
| KR102833568B1 (ko) | 2019-12-04 | 2025-07-11 | 삼성전자주식회사 | 생체정보 추산 장치 및 방법 |
| US20220117491A1 (en) * | 2020-01-23 | 2022-04-21 | Precision Healing, Inc. | Multispectral sample analysis using fluorescence signatures |
| US20220120676A1 (en) * | 2020-01-23 | 2022-04-21 | Precision Healing, Inc. | Multispectral sample analysis using absorption signatures |
| WO2021150808A1 (en) * | 2020-01-23 | 2021-07-29 | Precision Healing, Inc. | Skin diagnostics using optical signatures |
| US20240389931A1 (en) * | 2020-01-23 | 2024-11-28 | Precision Healing LLC | Wound care diagnosis with fluorescence signatures |
| US20240245346A1 (en) * | 2020-01-23 | 2024-07-25 | Precision Healing, Inc. | Image analysis using skin wound factors |
| WO2021236014A1 (en) * | 2020-05-21 | 2021-11-25 | Temasek Life Sciences Laboratory Limited | Raman optical biomarker for shade avoidance syndrome in plants |
| WO2021236015A1 (en) | 2020-05-21 | 2021-11-25 | Temasek Life Sciences Laboratory Limited | Early diagnosis and management of nitrogen deficiency in plants utilizing raman spectroscopy |
| CN111912828A (zh) * | 2020-08-19 | 2020-11-10 | 河南省农业科学院农副产品加工研究中心 | 一种快速检测玉米中类胡萝卜素含量的方法 |
| JP7256910B2 (ja) * | 2020-12-21 | 2023-04-12 | カゴメ株式会社 | 野菜摂取量改善システム、野菜摂取食データベース、及び野菜摂取量改善プログラム |
| CN113484303A (zh) * | 2021-07-01 | 2021-10-08 | 农业农村部食物与营养发展研究所 | 基于拉曼光谱检测小米类胡萝卜素的方法 |
| JP7521045B2 (ja) * | 2022-02-18 | 2024-07-23 | カゴメ株式会社 | 野菜摂取量改善システム、野菜摂取食データベース、及び野菜摂取量改善プログラム |
| JP7651200B2 (ja) * | 2023-05-24 | 2025-03-26 | 有限会社 ライブエイド | 測定装置、測定方法、およびプログラム |
| US20250389711A1 (en) * | 2024-06-20 | 2025-12-25 | Mohsen Sharifzadeh | Advanced Method for Accurate Optical Quantification of Antioxidant Carotenoids in Biological Tissues with Comprehensive Correction Techniques |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3563233A (en) | 1969-03-17 | 1971-02-16 | Albert G Bodine | Sonic dental tool for massaging gums |
| US4144464A (en) | 1978-01-25 | 1979-03-13 | The United States Of America As Represented By The United States Department Of Energy | Device and method for noresonantly Raman shifting ultraviolet radiation |
| US4318057A (en) | 1979-06-04 | 1982-03-02 | The United States Of America As Represented By The United States Department Of Energy | Optically pumped isotopic ammonia laser system |
| US4519400A (en) | 1983-04-01 | 1985-05-28 | Biosonics, Inc. | Method for stimulating salivation |
| US4500995A (en) | 1983-05-02 | 1985-02-19 | At&T Bell Laboratories | Bromine anti-stokes raman laser |
| US4665921A (en) | 1984-05-28 | 1987-05-19 | Teranishi Electric Works, Ltd. | High potential generating toothbrush |
| US5346488A (en) | 1985-04-08 | 1994-09-13 | The General Hospital Corporation | Laser-induced ablation of atherosclerotic plaque |
| US4758081A (en) | 1985-07-18 | 1988-07-19 | Bausch & Lomb Incorporated | Control of laser photocoagulation using Raman radiation |
| FR2591105B1 (fr) | 1985-12-11 | 1989-03-24 | Moet Hennessy Rech | Composition pharmaceutique, notamment dermatologique, ou cosmetique, a base de phases lamellaires lipidiques hydratees ou de liposomes contenant un retinoide ou un analogue structural dudit retinoide tel qu'un carotenoide. |
| CN87101867A (zh) | 1987-03-09 | 1988-09-21 | 王龄 | 电离子口腔治疗微电器 |
| US4852579A (en) | 1987-04-20 | 1989-08-01 | Karl Storz Endoscopy Gmbh And Company | Photocharacterization and treatment of normal abnormal and ectopic endometrium |
| US4832483A (en) | 1987-09-03 | 1989-05-23 | New England Medical Center Hospitals, Inc. | Method of using resonance raman spectroscopy for detection of malignancy disease |
| US4807240A (en) | 1988-01-11 | 1989-02-21 | Rockwell International Corporation | Frequency adding lasers and optical amplifiers |
| US4858238A (en) | 1988-01-14 | 1989-08-15 | The United States Of America As Represented By The Secretary Of The Air Force | Stimulated Raman scattering enhancer |
| US5421337A (en) | 1989-04-14 | 1995-06-06 | Massachusetts Institute Of Technology | Spectral diagnosis of diseased tissue |
| US5124313A (en) | 1989-06-02 | 1992-06-23 | Schaeffer Hans A | Methods of improved skin care and the treatment of dermatological conditions |
| US5290605A (en) | 1989-06-29 | 1994-03-01 | Niva Shapira | Sun-exposure nutritional supporting composition |
| US5376556A (en) | 1989-10-27 | 1994-12-27 | Abbott Laboratories | Surface-enhanced Raman spectroscopy immunoassay |
| US5243983A (en) | 1990-12-14 | 1993-09-14 | Georgia Tech Research Corporation | Non-invasive blood glucose measurement system and method using stimulated raman spectroscopy |
| US5261410A (en) * | 1991-02-07 | 1993-11-16 | Alfano Robert R | Method for determining if a tissue is a malignant tumor tissue, a benign tumor tissue, or a normal or benign tissue using Raman spectroscopy |
| US5303026A (en) | 1991-02-26 | 1994-04-12 | The Regents Of The University Of California Los Alamos National Laboratory | Apparatus and method for spectroscopic analysis of scattering media |
| EP0573535B1 (de) | 1991-02-26 | 2000-12-27 | Massachusetts Institute Of Technology | Molekularspektroskopieverfahren und -einrichtungen zur gewebediagnose |
| US5275168A (en) | 1992-03-31 | 1994-01-04 | The United States Of America As Represented By The Secretary Of The Navy | Time-gated imaging through dense-scattering materials using stimulated Raman amplification |
| US5452723A (en) | 1992-07-24 | 1995-09-26 | Massachusetts Institute Of Technology | Calibrated spectrographic imaging |
| US5418797A (en) | 1993-01-15 | 1995-05-23 | The United States Of America As Represented By The Secretary Of The Navy | Time gated imaging through scattering material using polarization and stimulated raman amplification |
| US5304170A (en) | 1993-03-12 | 1994-04-19 | Green Howard A | Method of laser-induced tissue necrosis in carotenoid-containing skin structures |
| US5553616A (en) | 1993-11-30 | 1996-09-10 | Florida Institute Of Technology | Determination of concentrations of biological substances using raman spectroscopy and artificial neural network discriminator |
| US5556612A (en) | 1994-03-15 | 1996-09-17 | The General Hospital Corporation | Methods for phototherapeutic treatment of proliferative skin diseases |
| US5451785A (en) | 1994-03-18 | 1995-09-19 | Sri International | Upconverting and time-gated two-dimensional infrared transillumination imaging |
| US5590660A (en) | 1994-03-28 | 1997-01-07 | Xillix Technologies Corp. | Apparatus and method for imaging diseased tissue using integrated autofluorescence |
| US5432610A (en) | 1994-04-15 | 1995-07-11 | Hewlett-Packard Company | Diode-pumped power build-up cavity for chemical sensing |
| US5579773A (en) | 1994-09-30 | 1996-12-03 | Martin Marietta Energy Systems, Inc. | Laser-induced differential normalized fluorescence method for cancer diagnosis |
| US5553617A (en) | 1995-01-20 | 1996-09-10 | Hughes Aircraft Company | Noninvasive method and apparatus for determining body chemistry |
| US5697373A (en) | 1995-03-14 | 1997-12-16 | Board Of Regents, The University Of Texas System | Optical method and apparatus for the diagnosis of cervical precancers using raman and fluorescence spectroscopies |
| US5615673A (en) * | 1995-03-27 | 1997-04-01 | Massachusetts Institute Of Technology | Apparatus and methods of raman spectroscopy for analysis of blood gases and analytes |
| US5643623A (en) | 1995-06-07 | 1997-07-01 | Mars Incorporated | Health food product and its uses |
| US5733507A (en) | 1995-06-07 | 1998-03-31 | Inphocyte, Inc. | Biological cell sample holder for use in infrared and/or Raman spectroscopy analysis holder |
| US5657754A (en) | 1995-07-10 | 1997-08-19 | Rosencwaig; Allan | Apparatus for non-invasive analyses of biological compounds |
| US5873831A (en) | 1997-03-13 | 1999-02-23 | The University Of Utah Technology Transfer Office | Method and system for measurement of macular carotenoid levels |
-
1999
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|---|---|
| EP1196088B1 (de) | 2009-09-09 |
| EP1196088A1 (de) | 2002-04-17 |
| JP2006078497A (ja) | 2006-03-23 |
| JP3786873B2 (ja) | 2006-06-14 |
| KR20060134230A (ko) | 2006-12-27 |
| JP4336673B2 (ja) | 2009-09-30 |
| WO2000078217A1 (en) | 2000-12-28 |
| KR100825521B1 (ko) | 2008-04-25 |
| KR100788536B1 (ko) | 2007-12-24 |
| DE60042931D1 (de) | 2009-10-22 |
| KR20020035007A (ko) | 2002-05-09 |
| KR20070004144A (ko) | 2007-01-05 |
| EP1196088A4 (de) | 2003-08-06 |
| AU3914400A (en) | 2001-01-09 |
| JP2003507088A (ja) | 2003-02-25 |
| CA2371886C (en) | 2012-01-03 |
| KR100845640B1 (ko) | 2008-07-10 |
| US6205354B1 (en) | 2001-03-20 |
| CA2371886A1 (en) | 2000-12-28 |
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