ATE442369T1 - Verfahren zur aufreinigung von riboflavin - Google Patents
Verfahren zur aufreinigung von riboflavinInfo
- Publication number
- ATE442369T1 ATE442369T1 AT04741171T AT04741171T ATE442369T1 AT E442369 T1 ATE442369 T1 AT E442369T1 AT 04741171 T AT04741171 T AT 04741171T AT 04741171 T AT04741171 T AT 04741171T AT E442369 T1 ATE442369 T1 AT E442369T1
- Authority
- AT
- Austria
- Prior art keywords
- riboflavin
- crystalline form
- isolating
- purifying
- purifying riboflavin
- Prior art date
Links
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 title abstract 18
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 title abstract 9
- 229960002477 riboflavin Drugs 0.000 title abstract 9
- 235000019192 riboflavin Nutrition 0.000 title abstract 9
- 239000002151 riboflavin Substances 0.000 title abstract 9
- 238000000034 method Methods 0.000 title abstract 2
- 230000001376 precipitating effect Effects 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P25/00—Preparation of compounds containing alloxazine or isoalloxazine nucleus, e.g. riboflavin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/12—Heterocyclic compounds containing pteridine ring systems containing pteridine ring systems condensed with carbocyclic rings or ring systems
- C07D475/14—Benz [g] pteridines, e.g. riboflavin
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03016512 | 2003-07-22 | ||
| PCT/EP2004/008097 WO2005014594A1 (en) | 2003-07-22 | 2004-07-20 | Process for the purification of riboflavin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE442369T1 true ATE442369T1 (de) | 2009-09-15 |
Family
ID=34130028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04741171T ATE442369T1 (de) | 2003-07-22 | 2004-07-20 | Verfahren zur aufreinigung von riboflavin |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7670800B2 (de) |
| EP (1) | EP1670799B1 (de) |
| JP (1) | JP4895810B2 (de) |
| KR (1) | KR20060063908A (de) |
| CN (1) | CN1826342B (de) |
| AT (1) | ATE442369T1 (de) |
| DE (1) | DE602004023101D1 (de) |
| ES (1) | ES2332787T3 (de) |
| WO (1) | WO2005014594A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012233033B2 (en) * | 2006-01-27 | 2014-11-06 | Terumo Bct Biotechnologies, Llc | Methods and compositions for the production of high concentration alloxazine solutions |
| CA2849644A1 (en) * | 2006-01-27 | 2007-08-09 | Terumo Bct Biotechnologies, Llc | Composition for treating a blood product with a concentration alloxazine solution |
| JP2017536834A (ja) * | 2014-12-10 | 2017-12-14 | ビーエーエスエフ ソシエタス・ヨーロピアBasf Se | バイオテクノロジー生成物からdnaを除去する方法 |
| CN109851619B (zh) * | 2019-02-02 | 2021-04-23 | 赤峰制药股份有限公司 | 一种核黄素提纯工艺 |
| CN111072664B (zh) * | 2019-12-30 | 2021-03-23 | 北京和合医学诊断技术股份有限公司 | 一种纯化维生素b2的方法 |
| JP2023530890A (ja) * | 2020-06-23 | 2023-07-20 | ディーエスエム アイピー アセッツ ビー.ブイ. | 発酵プロセス |
| CN113929683A (zh) * | 2021-11-15 | 2022-01-14 | 天津大学 | 一种提高核黄素晶体堆密度和流动性的方法 |
| CN113943291B (zh) * | 2021-11-30 | 2023-09-08 | 湖北广济药业股份有限公司 | 一种核酸酶去除核黄素中的残留dna的方法 |
| KR102692455B1 (ko) * | 2022-06-15 | 2024-08-07 | 씨제이제일제당 주식회사 | 리보플라빈 결정화 공정 및 장치 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2324800A (en) * | 1941-08-14 | 1943-07-20 | Pfizer Charles & Co | Purification of riboflavin |
| US2367646A (en) * | 1943-05-28 | 1945-01-16 | Commercial Solvents Corp | Process for recovering crystalline riboflavin |
| US2603633A (en) * | 1950-01-26 | 1952-07-15 | Commercial Solvents Corp | Crystalline form of riboflavin |
| US2797215A (en) * | 1955-04-28 | 1957-06-25 | Commercial Solvents Corp | Production of type a riboflavin crystals |
| US4165250A (en) | 1975-08-29 | 1979-08-21 | Merck & Co., Inc. | Riboflavin purification |
| US4368963A (en) * | 1978-06-29 | 1983-01-18 | Michael Stolov | Multicolor image or picture projecting system using electronically controlled slides |
| US4779209A (en) * | 1982-11-03 | 1988-10-18 | Wang Laboratories, Inc. | Editing voice data |
| DE3247381A1 (de) * | 1982-12-22 | 1984-06-28 | Basf Ag, 6700 Ludwigshafen | Verbessertes verfahren zum reinigen von riboflavin |
| EP0137226B1 (de) * | 1983-09-09 | 1990-11-14 | Daicel Chemical Industries, Ltd. | Verfahren zur Herstellung von Riboflavin |
| DE3421714A1 (de) * | 1984-06-12 | 1985-12-12 | Basf Ag, 6700 Ludwigshafen | Verfahren zur reinigung von riboflavin |
| JPS6121096A (ja) * | 1984-07-11 | 1986-01-29 | Daicel Chem Ind Ltd | リボフラビンの取得方法 |
| US5309546A (en) * | 1984-10-15 | 1994-05-03 | Baker Bruce R | System for method for producing synthetic plural word messages |
| US4771425A (en) * | 1984-10-29 | 1988-09-13 | Stratacom, Inc. | Synchoronous packet voice/data communication system |
| JPH0753120B2 (ja) * | 1986-10-16 | 1995-06-07 | ダイセル化学工業株式会社 | リボフラビンの取得方法 |
| EP0307767B1 (de) * | 1987-09-18 | 1993-07-21 | F. Hoffmann-La Roche Ag | Neue Form des Riboflavins |
| JPH02110658A (ja) * | 1988-10-19 | 1990-04-23 | Hitachi Ltd | 文書編集装置 |
| US5103005A (en) * | 1989-07-21 | 1992-04-07 | Coors Biotech, Inc. | Method for recovery of riboflavin |
| DE4002066A1 (de) | 1990-01-25 | 1991-08-01 | Basf Ag | Verfahren zur abtrennung von riboflavin aus fermentationssuspensionen |
| DE4021274A1 (de) * | 1990-07-04 | 1992-01-09 | Basf Ag | Verfahren zur reinigung von fermentativ hergestelltem riboflavin |
| JPH0665244A (ja) * | 1991-03-12 | 1994-03-08 | Takeda Chem Ind Ltd | リボフラビンの精製法 |
| JPH06192261A (ja) * | 1991-03-14 | 1994-07-12 | Takeda Chem Ind Ltd | リボフラビンの精製法 |
| EP0530378B1 (de) * | 1991-03-20 | 1999-01-07 | Mitsubishi Denki Kabushiki Kaisha | Anzeigevorrichtung vom projektionstyp |
| EP0515084B1 (de) * | 1991-05-24 | 2000-07-05 | Imperial Chemical Industries Plc | Wärmeempfindliche Farbstoffübertragungsdruckschicht |
| KR960013313B1 (ko) * | 1991-07-12 | 1996-10-02 | 가부시키가이샤 한도오따이 에네루기 겐큐쇼 | 전기광학 표시장치 |
| US5444768A (en) * | 1991-12-31 | 1995-08-22 | International Business Machines Corporation | Portable computer device for audible processing of remotely stored messages |
| JP3086069B2 (ja) * | 1992-06-16 | 2000-09-11 | キヤノン株式会社 | 障害者用情報処理装置 |
| US5359345A (en) * | 1992-08-05 | 1994-10-25 | Cree Research, Inc. | Shuttered and cycled light emitting diode display and method of producing the same |
| US5640590A (en) * | 1992-11-18 | 1997-06-17 | Canon Information Systems, Inc. | Method and apparatus for scripting a text-to-speech-based multimedia presentation |
| JPH07170288A (ja) * | 1993-12-15 | 1995-07-04 | Hitachi Ltd | 音声通信システムおよび音声通信方法 |
| US5491774A (en) * | 1994-04-19 | 1996-02-13 | Comp General Corporation | Handheld record and playback device with flash memory |
| US5572442A (en) * | 1994-07-21 | 1996-11-05 | Information Highway Media Corporation | System for distributing subscription and on-demand audio programming |
| US5557541A (en) * | 1994-07-21 | 1996-09-17 | Information Highway Media Corporation | Apparatus for distributing subscription and on-demand audio programming |
| CA2139081C (en) * | 1994-12-23 | 1999-02-02 | Alastair Gordon | Unified messaging system and method |
| EP0730034A1 (de) * | 1995-03-03 | 1996-09-04 | F. Hoffmann-La Roche Ag | Reinigung von Riboflavin |
| CN1056845C (zh) * | 1995-03-03 | 2000-09-27 | 弗·哈夫曼-拉罗切有限公司 | 核黄素的纯化 |
| US5664228A (en) * | 1995-08-09 | 1997-09-02 | Microsoft Corporation | Portable information device and system and method for downloading executable instructions from a computer to the portable information device |
| CA2282908A1 (en) * | 1998-10-19 | 2000-04-19 | F. Hoffmann-La Roche Ag | Purification and crystallization process for riboflavin |
| US6723346B1 (en) * | 1999-04-30 | 2004-04-20 | Roche Vitamins Inc. | Process for preparing spray granules containing riboflavin |
-
2004
- 2004-07-20 AT AT04741171T patent/ATE442369T1/de not_active IP Right Cessation
- 2004-07-20 DE DE602004023101T patent/DE602004023101D1/de not_active Expired - Lifetime
- 2004-07-20 CN CN2004800211488A patent/CN1826342B/zh not_active Expired - Fee Related
- 2004-07-20 ES ES04741171T patent/ES2332787T3/es not_active Expired - Lifetime
- 2004-07-20 JP JP2006520776A patent/JP4895810B2/ja not_active Expired - Fee Related
- 2004-07-20 US US10/565,443 patent/US7670800B2/en not_active Expired - Lifetime
- 2004-07-20 WO PCT/EP2004/008097 patent/WO2005014594A1/en not_active Ceased
- 2004-07-20 EP EP04741171A patent/EP1670799B1/de not_active Expired - Lifetime
- 2004-07-20 KR KR1020067001432A patent/KR20060063908A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| US7670800B2 (en) | 2010-03-02 |
| US20060240112A1 (en) | 2006-10-26 |
| ES2332787T3 (es) | 2010-02-12 |
| KR20060063908A (ko) | 2006-06-12 |
| EP1670799A1 (de) | 2006-06-21 |
| CN1826342A (zh) | 2006-08-30 |
| DE602004023101D1 (de) | 2009-10-22 |
| JP2006528150A (ja) | 2006-12-14 |
| WO2005014594A1 (en) | 2005-02-17 |
| CN1826342B (zh) | 2010-06-16 |
| EP1670799B1 (de) | 2009-09-09 |
| JP4895810B2 (ja) | 2012-03-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |