ATE442866T1 - Fusionsproteine aus mycobakterium tuberculosis - Google Patents

Fusionsproteine aus mycobakterium tuberculosis

Info

Publication number
ATE442866T1
ATE442866T1 AT01946661T AT01946661T ATE442866T1 AT E442866 T1 ATE442866 T1 AT E442866T1 AT 01946661 T AT01946661 T AT 01946661T AT 01946661 T AT01946661 T AT 01946661T AT E442866 T1 ATE442866 T1 AT E442866T1
Authority
AT
Austria
Prior art keywords
fusion proteins
compositions
mycobacterium tuberculosis
tuberculosis
mycobacterium
Prior art date
Application number
AT01946661T
Other languages
English (en)
Inventor
Yasir Skeiky
Steven Reed
Mark Alderson
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/597,796 external-priority patent/US7186412B1/en
Application filed by Corixa Corp filed Critical Corixa Corp
Application granted granted Critical
Publication of ATE442866T1 publication Critical patent/ATE442866T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT01946661T 2000-06-20 2001-06-20 Fusionsproteine aus mycobakterium tuberculosis ATE442866T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/597,796 US7186412B1 (en) 1998-04-07 2000-06-20 Fusion proteins of Mycobacterium tuberculosis
US26573701P 2001-02-01 2001-02-01
PCT/US2001/019959 WO2001098460A2 (en) 2000-06-20 2001-06-20 Fusion proteins of mycobacterium tuberculosis

Publications (1)

Publication Number Publication Date
ATE442866T1 true ATE442866T1 (de) 2009-10-15

Family

ID=40253655

Family Applications (2)

Application Number Title Priority Date Filing Date
AT01946661T ATE442866T1 (de) 2000-06-20 2001-06-20 Fusionsproteine aus mycobakterium tuberculosis
AT09170183T ATE526994T1 (de) 2000-06-20 2001-06-20 Mtb32a antigen aus mycobakterium tuberculosis mit inaktivierter protease aktivität und fusionsproteine die das antigen enthalten

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT09170183T ATE526994T1 (de) 2000-06-20 2001-06-20 Mtb32a antigen aus mycobakterium tuberculosis mit inaktivierter protease aktivität und fusionsproteine die das antigen enthalten

Country Status (13)

Country Link
US (7) US7083796B2 (de)
EP (2) EP2133100B1 (de)
JP (2) JP5139618B2 (de)
AT (2) ATE442866T1 (de)
AU (2) AU6867801A (de)
CA (1) CA2413959C (de)
CY (2) CY1109531T1 (de)
DE (1) DE60139963D1 (de)
DK (2) DK2133100T3 (de)
ES (2) ES2374620T3 (de)
PT (2) PT1542732E (de)
SI (1) SI1542732T1 (de)
WO (1) WO2001098460A2 (de)

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US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6592877B1 (en) * 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US7083796B2 (en) * 2000-06-20 2006-08-01 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
US8143386B2 (en) * 1999-04-07 2012-03-27 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
ES2282142T3 (es) * 1999-10-07 2007-10-16 Corixa Corporation Una secuencia de micobacterium tuberculosis para la expresion de proteinas heterologas.
WO2001024820A1 (en) * 1999-10-07 2001-04-12 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
AU2001241738A1 (en) * 2000-02-25 2001-09-03 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
US7026465B2 (en) * 2002-02-15 2006-04-11 Corixa Corporation Fusion proteins of Mycobacterium tuberculosis
SG159555A1 (en) 2004-11-16 2010-03-30 Crucell Holland Bv Multivalent vaccines comprising recombinant viral vectors
CN105903008B (zh) * 2005-04-29 2020-01-03 葛兰素史密丝克莱恩生物有限公司 用于预防或治疗结核分枝杆菌感染的新方法
AU2011224145B2 (en) * 2005-04-29 2013-05-16 Glaxosmithkline Biologicals S.A. Novel method for preventing or treating M tuberculosis infection
CA2606962A1 (en) * 2005-04-29 2006-11-09 Fusion Antibodies Limited Assays for diagnosis of tuberculosis and uses thereof
EP2426141B1 (de) * 2005-04-29 2014-10-01 GlaxoSmithKline Biologicals S.A. Verfahren zur Vorbeugung oder Behandlung einer M-tuberculosis-Infektion
US20070081944A1 (en) * 2005-09-30 2007-04-12 Reed Steven G Iontophoresis apparatus and method for the diagnosis of tuberculosis
ES2621211T3 (es) 2007-04-04 2017-07-03 Infectious Disease Research Institute Composiciones inmunogénicas que comprenden polipéptidos de mycobacterium tuberculosis y fusiones de los mismos
MX2010003972A (es) * 2007-10-13 2010-08-09 Univ Cornell Composiciones para producir una respuesta inmune contra para-tuberculosis sub-especie mycobacterium avium.
KR101378240B1 (ko) * 2008-02-22 2014-03-28 포항공과대학교 산학협력단 결핵 예방용 조성물
HUE037121T2 (hu) 2008-07-25 2018-08-28 Glaxosmithkline Biologicals Sa Új készítmények és eljárások
MX2011000982A (es) 2008-07-25 2011-03-02 Glaxosmithkline Biolog Sa La proteina de tuberculosis rv2386c, composiciones y usos de la misma.
PT2315773T (pt) * 2008-07-25 2016-11-23 Glaxosmithkline Biologicals Sa Polipéptidos, polinucleótidos e composições para utilização no tratamento de tuberculose latente
SI2528621T1 (sl) 2010-01-27 2017-01-31 Glaxosmithkline Biologicals S.A., Modificirani tuberkolozni antigeni
PL2651436T3 (pl) 2010-12-14 2016-10-31 Kompozycja antygenów mykobakteryjnych
WO2013063059A1 (en) * 2011-10-24 2013-05-02 University Of Central Florida Research Foundation, Inc. Plastid-expressed mycobacterium tuberculosis vaccine antigens esat-6 and mtb72f fused to cholera toxin b subunit
EP2812704A4 (de) * 2012-02-07 2016-03-23 Intuitive Biosciences Inc Mycobakteriumstuberkulose-spezifische peptide zur erkennung einer infektion oder immunisierung nichtmenschlicher primaten
MX347154B (es) 2012-02-24 2017-02-21 Centro De Investigación Científica Y De Educación Superior De Ensenada Baja California (Cicese) Prueba de diagnóstico para enfermedades infecciosas en ganado bovino.
GB201513176D0 (en) * 2015-07-27 2015-09-09 Glaxosmithkline Biolog Sa Novel methods for inducing an immune response

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US20090018095A1 (en) 2009-01-15
US7083796B2 (en) 2006-08-01
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JP5139618B2 (ja) 2013-02-06
EP2133100B1 (de) 2011-10-05
EP1542732A2 (de) 2005-06-22
CY1112171T1 (el) 2015-12-09
JP2004526405A (ja) 2004-09-02
SI1542732T1 (sl) 2010-01-29
DK2133100T3 (da) 2012-01-23
WO2001098460A3 (en) 2004-10-28
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US7976844B2 (en) 2011-07-12
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ATE526994T1 (de) 2011-10-15
CA2413959C (en) 2015-07-07
US20060193876A1 (en) 2006-08-31
US20080317716A1 (en) 2008-12-25
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CA2413959A1 (en) 2001-12-27
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