ATE443139T1 - Menschliche toll-ähliche rezeptorproteine, zugehörige reagenzien und verfahren - Google Patents

Menschliche toll-ähliche rezeptorproteine, zugehörige reagenzien und verfahren

Info

Publication number
ATE443139T1
ATE443139T1 AT06025414T AT06025414T ATE443139T1 AT E443139 T1 ATE443139 T1 AT E443139T1 AT 06025414 T AT06025414 T AT 06025414T AT 06025414 T AT06025414 T AT 06025414T AT E443139 T1 ATE443139 T1 AT E443139T1
Authority
AT
Austria
Prior art keywords
methods
receptor proteins
receptors
human toll
human
Prior art date
Application number
AT06025414T
Other languages
English (en)
Inventor
Gerard Hardiman
Fernando J Bazan
Fernando L Rock
Robert A Kastelein
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27366459&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE443139(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE443139T1 publication Critical patent/ATE443139T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT06025414T 1997-05-07 1998-05-07 Menschliche toll-ähliche rezeptorproteine, zugehörige reagenzien und verfahren ATE443139T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4429397P 1997-05-07 1997-05-07
US7221298P 1998-01-22 1998-01-22
US7694798P 1998-03-05 1998-03-05

Publications (1)

Publication Number Publication Date
ATE443139T1 true ATE443139T1 (de) 2009-10-15

Family

ID=27366459

Family Applications (3)

Application Number Title Priority Date Filing Date
AT07123073T ATE458053T1 (de) 1997-05-07 1998-05-07 Menschliche toll-like-rezeptorproteine, zugehörige reagenzien und verfahren
AT98918934T ATE348157T1 (de) 1997-05-07 1998-05-07 Menschliche toll-ähnliche rezeptorproteine, zugehörige reagenzien und verfahren
AT06025414T ATE443139T1 (de) 1997-05-07 1998-05-07 Menschliche toll-ähliche rezeptorproteine, zugehörige reagenzien und verfahren

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AT07123073T ATE458053T1 (de) 1997-05-07 1998-05-07 Menschliche toll-like-rezeptorproteine, zugehörige reagenzien und verfahren
AT98918934T ATE348157T1 (de) 1997-05-07 1998-05-07 Menschliche toll-ähnliche rezeptorproteine, zugehörige reagenzien und verfahren

Country Status (19)

Country Link
EP (4) EP1988166A1 (de)
JP (4) JP2002514083A (de)
KR (1) KR100388860B1 (de)
CN (4) CN101486759A (de)
AT (3) ATE458053T1 (de)
AU (1) AU740333B2 (de)
CA (1) CA2289912C (de)
CY (1) CY1109645T1 (de)
DE (3) DE69841514D1 (de)
DK (2) DK0980429T3 (de)
ES (3) ES2331622T3 (de)
ID (1) ID28299A (de)
IL (1) IL132614A0 (de)
NO (1) NO995458D0 (de)
NZ (1) NZ338073A (de)
PL (1) PL336635A1 (de)
PT (1) PT1798288E (de)
SK (1) SK146599A3 (de)
WO (1) WO1998050547A2 (de)

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AU2003203679B2 (en) * 1997-10-17 2007-04-05 Genentech, Inc. Human toll homologues
JP2000128900A (ja) * 1998-10-26 2000-05-09 Japan Science & Technology Corp 新規トル様（Ｔｏｌｌ−ｌｉｋｅ）レセプター及びその遺伝子
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JP4566494B2 (ja) * 1999-11-02 2010-10-20 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド ＣｐＧレセプター（ＣｐＧ−Ｒ）およびＣｐＧ−Ｒに関する方法
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US20030083244A1 (en) * 2000-04-26 2003-05-01 Vernet Corine A.M. Novel proteins and nucleic acids encoding same
NZ522327A (en) * 2000-05-25 2004-09-24 Schering Corp Mammalian DNAX Toll-like receptor protein, DTLR 10, antibodies and medicaments made therefrom and use in treating immunological disorders
AU2001268427B2 (en) 2000-06-16 2007-03-29 Glaxosmithkline Intellectual Property Limited Antibodies that immunospecifically bind to blys
US7879328B2 (en) 2000-06-16 2011-02-01 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to B lymphocyte stimulator
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AU2003287316A1 (en) * 2002-12-11 2004-06-30 3M Innovative Properties Company Assays relating to toll-like receptor activity
WO2004094671A2 (en) * 2003-04-22 2004-11-04 Coley Pharmaceutical Gmbh Methods and products for identification and assessment of tlr ligands
US7696169B2 (en) 2003-06-06 2010-04-13 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
CA2882022A1 (en) 2003-09-11 2005-03-24 Walter Newman Monoclonal antibodies against hmgb1
TW200514850A (en) * 2003-10-03 2005-05-01 Hitachi Chemical Co Ltd Method of evaluating risk for viral infection
TW200516153A (en) * 2003-10-03 2005-05-16 Hitachi Chemical Co Ltd Human toll-like receptor 3 gene polymorphism as marker for inherited factor of allergic disease and utilization of the same
CA2540541C (en) 2003-10-03 2012-03-27 3M Innovative Properties Company Alkoxy substituted imidazoquinolines
WO2005039504A2 (en) 2003-10-24 2005-05-06 Eisai Co., Ltd. Compounds and methods for treating toll-like receptor 2-related diseases and conditions
WO2005051317A2 (en) 2003-11-25 2005-06-09 3M Innovative Properties Company Substituted imidazo ring systems and methods
JP2008022701A (ja) * 2004-09-24 2008-02-07 Japan Science & Technology Agency 可溶型Ｔｏｌｌ様受容体４タンパク質
CA2587676A1 (en) 2004-11-19 2006-05-26 Institut Gustave Roussy Improved treatment of cancer by double-stranded rna
AR051836A1 (es) 2004-11-30 2007-02-14 Centocor Inc Antagonistas de receptor 3 simil toll metodos y usos
WO2006084251A2 (en) 2005-02-04 2006-08-10 Coley Pharmaceutical Group, Inc. Aqueous gel formulations containing immune reponse modifiers
US7700728B2 (en) 2005-03-24 2010-04-20 Schering Corporation Use of chimeric receptors in a screening assay for identifying agonists and antagonists of cell receptors
US7498409B2 (en) 2005-03-24 2009-03-03 Schering Corporation Screening assay for TLR7, TLR8 and TLR9 agonists and antagonists
US9168286B2 (en) 2005-10-13 2015-10-27 Human Genome Sciences, Inc. Methods and compositions for use in treatment of patients with autoantibody positive disease
DK1945820T3 (da) 2005-10-27 2013-11-11 Janssen Biotech Inc Toll-lignende receptor-3-modulatorer, fremgangsmåder og anvendelser
US20070224205A1 (en) 2006-03-07 2007-09-27 Powell Thomas J Compositions that include hemagglutinin, methods of making and methods of use thereof
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CN101134046B (zh) * 2006-09-01 2011-10-05 中国医学科学院药物研究所 Tlr4和tlr9激动剂复方在抑制肿瘤转移中的应用
EP2155889A4 (de) * 2007-05-25 2010-06-16 Centocor Ortho Biotech Inc Toll-artige rezeptor-3-modulatoren und verwendungen dafür
CA2722589A1 (en) 2008-04-25 2009-10-29 Innate Pharma Improved tlr3 agonist compositions
EP2116602A1 (de) 2008-05-07 2009-11-11 Institut Gustave Roussy Kombinationsprodukte zur Behandlung von Krebs
DK2334703T3 (en) 2008-09-17 2015-10-05 Innate Pharma Configurations and methods for detection of tlr3
EP2328911A4 (de) 2008-09-22 2012-03-14 Cedars Sinai Medical Center Kurzes menschliches md-2 als negativer regulator der toll-like-rezeptor-4-signalisierung
US9512196B2 (en) 2008-09-22 2016-12-06 Cedars-Sinai Medical Center Short-form human MD-2 as a negative regulator of toll-like receptor 4 signaling
ES2543095T3 (es) 2009-07-10 2015-08-14 Innate Pharma Agentes de unión a TLR3
JP5830744B2 (ja) * 2009-08-19 2015-12-09 国立大学法人東京工業大学 乳酸菌の付着性を誘導するペプチド及びその用途
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US9814740B2 (en) 2010-12-21 2017-11-14 Duke University Methods and compositions combining immunotherapy with monocyte activation
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Also Published As

Publication number Publication date
EP1798288A2 (de) 2007-06-20
HK1112018A1 (en) 2008-08-22
IL132614A0 (en) 2001-03-19
HK1102720A1 (en) 2007-12-07
HK1022175A1 (en) 2000-07-28
NO995458L (no) 1999-11-08
CY1109645T1 (el) 2012-05-23
CN1225555C (zh) 2005-11-02
WO1998050547A2 (en) 1998-11-12
EP1798288A3 (de) 2007-09-12
ES2279572T3 (es) 2007-08-16
EP1925666B1 (de) 2010-02-17
ATE458053T1 (de) 2010-03-15
NZ338073A (en) 2001-09-28
JP2002514083A (ja) 2002-05-14
DE69841170D1 (de) 2009-10-29
ATE348157T1 (de) 2007-01-15
DE69836630D1 (de) 2007-01-25
DE69841514D1 (de) 2010-04-01
DK0980429T3 (da) 2007-04-10
EP1988166A1 (de) 2008-11-05
EP0980429A2 (de) 2000-02-23
ES2340210T3 (es) 2010-05-31
KR20010012323A (ko) 2001-02-15
PT1798288E (pt) 2009-12-23
AU740333B2 (en) 2001-11-01
CA2289912C (en) 2011-07-26
DE69836630T2 (de) 2007-10-11
JP2006052232A (ja) 2006-02-23
KR100388860B1 (ko) 2003-06-25
WO1998050547A3 (en) 1999-03-11
JP2009089713A (ja) 2009-04-30
EP1925666A1 (de) 2008-05-28
CN1263555A (zh) 2000-08-16
DK1798288T3 (da) 2010-01-04
CN1800214A (zh) 2006-07-12
ID28299A (id) 2001-05-10
EP1798288B1 (de) 2009-09-16
AU7175498A (en) 1998-11-27
NO995458D0 (no) 1999-11-08
CA2289912A1 (en) 1998-11-12
ES2331622T3 (es) 2010-01-11
PL336635A1 (en) 2000-07-03
CN101486759A (zh) 2009-07-22
CN1935840A (zh) 2007-03-28
EP0980429B1 (de) 2006-12-13
JP2005120106A (ja) 2005-05-12
SK146599A3 (en) 2000-07-11

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