ATE444301T1 - Verbindungen auf glukosebasis mit affinitüt für p-selektin - Google Patents

Verbindungen auf glukosebasis mit affinitüt für p-selektin

Info

Publication number: ATE444301T1
Authority: AT; Austria
Prior art keywords: selectin; glucose; based compounds; affinity; relates
Prior art date: 2002-10-11

Application number

AT03769400T

Other languages

English (en)

Inventor

Chantal Appeldoorn

Erik Biessen

Thomas Molenaar

Berkel Theodorus Van

Original Assignee

Astellas Pharma Europ B V

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-10-11

Filing date

2003-10-13

Publication date

2009-10-15

2003-10-13 Application filed by Astellas Pharma Europ B V filed Critical Astellas Pharma Europ B V

2009-10-15 Application granted granted Critical

2009-10-15 Publication of ATE444301T1 publication Critical patent/ATE444301T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 5
102000008212 P-Selectin Human genes 0.000 abstract 3
108010035766 P-Selectin Proteins 0.000 abstract 3
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 2
239000008103 glucose Substances 0.000 abstract 2
239000000562 conjugate Substances 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
238000012377 drug delivery Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Genetics & Genomics (AREA)
Oncology (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Hematology (AREA)
Biotechnology (AREA)
Rheumatology (AREA)
Biochemistry (AREA)
Crystallography & Structural Chemistry (AREA)
Epidemiology (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Neurosurgery (AREA)
Pulmonology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Physical Education & Sports Medicine (AREA)
Communicable Diseases (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT03769400T 2002-10-11 2003-10-13 Verbindungen auf glukosebasis mit affinitüt für p-selektin ATE444301T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP02079232		2002-10-11
PCT/EP2003/011457 WO2004033473A1 (en)	2002-10-11	2003-10-13	Glucose-based compounds with affinity to p-selectin

Publications (1)

Publication Number	Publication Date
ATE444301T1 true ATE444301T1 (de)	2009-10-15

Family

ID=32088032

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03769400T ATE444301T1 (de)	2002-10-11	2003-10-13	Verbindungen auf glukosebasis mit affinitüt für p-selektin

Country Status (11)

Country	Link
US (1)	US7304039B2 (de)
EP (1)	EP1549658B1 (de)
JP (1)	JP4603888B2 (de)
AT (1)	ATE444301T1 (de)
AU (1)	AU2003278090A1 (de)
BR (1)	BR0315231A (de)
CA (1)	CA2501842C (de)
DE (1)	DE60329511D1 (de)
ES (1)	ES2334220T3 (de)
MX (1)	MXPA05003844A (de)
WO (1)	WO2004033473A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2011127136A1 (en) *	2010-04-06	2011-10-13	University Of Chicago	Composition and methods related to modification of 5-hydroxymethylcytosine (5-hmc)
AU2011285703B2 (en) *	2010-08-04	2016-03-10	Wisconsin Alumni Research Foundation	Methods and pharmaceutical compositions for treating adverse or deleterious sequellae of traumatic brain injury
US20230372492A1 (en) *	2020-10-01	2023-11-23	Mississippi State University	Drugs conjugated with hexose phosphate and methods of making and using same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994005314A1 (en) *	1992-09-08	1994-03-17	Centocor, Inc.	Peptide inhibitors of leukocyte adhesion
CN1125449A (zh) *	1993-05-14	1996-06-26	萨依特尔有限公司	作为细胞粘附抑制剂的唾液基Lex类似物
JPH10508580A (ja)	1994-09-20	1998-08-25	ファルマシア・アンド・アップジョン・カンパニー	Ｅおよびｐセレクチンに対するリガンドのオリゴ糖構造
CA2260854A1 (en)	1996-08-08	1998-02-19	Novartis Ag	Modified oligosaccharides
US5830871A (en)	1996-10-28	1998-11-03	The Scripps Research Institute	Inhibitors of E-, P- and L-selectin binding
AU4700497A (en) *	1996-08-26	1998-03-19	Novartis Ag	Organic compounds
AU1144799A (en) *	1997-08-26	1999-03-16	Novartis Ag	Organic compounds
EP1288222A1 (de)	2001-09-03	2003-03-05	Yamanouchi Europe B.V.	Selektiv P-Selectin bindende peptidische Verbindungen
EP1527086B1 (de)	2002-08-09	2008-01-09	Astellas Pharma Europe B.V.	Verbindungen die p-selectin binden

2003
- 2003-10-13 AT AT03769400T patent/ATE444301T1/de not_active IP Right Cessation
- 2003-10-13 BR BR0315231-6A patent/BR0315231A/pt not_active IP Right Cessation
- 2003-10-13 CA CA2501842A patent/CA2501842C/en not_active Expired - Fee Related
- 2003-10-13 EP EP03769400A patent/EP1549658B1/de not_active Expired - Lifetime
- 2003-10-13 US US10/530,601 patent/US7304039B2/en not_active Expired - Fee Related
- 2003-10-13 WO PCT/EP2003/011457 patent/WO2004033473A1/en not_active Ceased
- 2003-10-13 AU AU2003278090A patent/AU2003278090A1/en not_active Abandoned
- 2003-10-13 ES ES03769400T patent/ES2334220T3/es not_active Expired - Lifetime
- 2003-10-13 JP JP2004542495A patent/JP4603888B2/ja not_active Expired - Fee Related
- 2003-10-13 DE DE60329511T patent/DE60329511D1/de not_active Expired - Lifetime
- 2003-10-13 MX MXPA05003844A patent/MXPA05003844A/es unknown

Also Published As

Publication number	Publication date
CA2501842A1 (en)	2004-04-22
ES2334220T3 (es)	2010-03-08
US7304039B2 (en)	2007-12-04
US20050261207A1 (en)	2005-11-24
BR0315231A (pt)	2005-08-23
WO2004033473A1 (en)	2004-04-22
AU2003278090A1 (en)	2004-05-04
MXPA05003844A (es)	2005-06-22
CA2501842C (en)	2012-07-17
EP1549658A1 (de)	2005-07-06
DE60329511D1 (de)	2009-11-12
EP1549658B1 (de)	2009-09-30
JP4603888B2 (ja)	2010-12-22
JP2006503876A (ja)	2006-02-02

Legal Events

Date	Code	Title	Description
2010-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

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NZ527157A (en)	2005-04-29	Compositions for delivering bisphosphonates
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CY1107906T1 (el)	2013-09-04	Φαρμακευτικη συνθεση που περιλαμβανει παραγωγα οιστετρολης για χρηση στην θεραπεια κατα του καρκινου
CY1111470T1 (el)	2015-08-05	Νεες φαρμακευτικες συνθεσεις που περιεχουν φλιβανσερινη πολυμορφη α
DE60034240D1 (de)	2007-05-16	Drogen zur behandlung maligner tumoren
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MY145074A (en)	2011-12-15	Thiazolidin-4-one derivatives
DE69920757D1 (de)	2004-11-04	Immunsuppressive wirkungen von pteridinderivaten
EA200501203A1 (ru)	2006-06-30	Жидкие фармацевтические композиции палоносетрона
SI1506185T1 (sl)	2006-10-31	Spojine in njihova uporaba kot inhibitorji 5-HT
EP1587506A4 (de)	2006-05-24	Verabreichung von capsaicinoiden
EA200501821A1 (ru)	2006-06-30	Фармацевтическая комбинация, содержащая модафинил и другой лекарственный препарат
WO2005117895A8 (en)	2006-05-18	Compositions comprising meloxicam
DK1359939T3 (da)	2007-02-26	Sammensætning og fremgangsmåde til potensering af lægemidler
DE60329511D1 (de)	2009-11-12	Verbindungen auf glukosebasis mit affinitüt für p-selektin
AU2003210850A8 (en)	2003-09-02	N-substituted3-hydroxy-4-pyridinones and pharmaceuticals containing thereof
DK1212072T3 (da)	2004-06-21	Farmaceutisk præparat omfattende eukalyptus- og orangeolie
AU2003281468A1 (en)	2004-02-09	P-glycoprotein inhibitor comprising octilonium bromide as an effective ingredient
WO2004026319A3 (en)	2004-09-02	Pharmaceutical compositions increasing camp useful for the treatment of cancers
SE0203817D0 (sv)	2002-12-20	New composition