ATE444309T1 - Immuntherapie für kronische myelozytische leukämie mit nacktem anti-nca-90 antikörper - Google Patents

Immuntherapie für kronische myelozytische leukämie mit nacktem anti-nca-90 antikörper

Info

Publication number
ATE444309T1
ATE444309T1 AT01957479T AT01957479T ATE444309T1 AT E444309 T1 ATE444309 T1 AT E444309T1 AT 01957479 T AT01957479 T AT 01957479T AT 01957479 T AT01957479 T AT 01957479T AT E444309 T1 ATE444309 T1 AT E444309T1
Authority
AT
Austria
Prior art keywords
immunotherapy
myelocytic leukemia
antibodies
naked anti
cronic
Prior art date
Application number
AT01957479T
Other languages
English (en)
Inventor
David Goldenberg
Hans Hansen
Original Assignee
Immunomedics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunomedics Inc filed Critical Immunomedics Inc
Application granted granted Critical
Publication of ATE444309T1 publication Critical patent/ATE444309T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT01957479T 2000-08-08 2001-08-08 Immuntherapie für kronische myelozytische leukämie mit nacktem anti-nca-90 antikörper ATE444309T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22369800P 2000-08-08 2000-08-08
PCT/US2001/024691 WO2002012347A1 (en) 2000-08-08 2001-08-08 Immunotherapy for chronic myelocytic leukemia

Publications (1)

Publication Number Publication Date
ATE444309T1 true ATE444309T1 (de) 2009-10-15

Family

ID=22837639

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01957479T ATE444309T1 (de) 2000-08-08 2001-08-08 Immuntherapie für kronische myelozytische leukämie mit nacktem anti-nca-90 antikörper

Country Status (10)

Country Link
US (2) US6759045B2 (de)
EP (1) EP1309627B1 (de)
JP (1) JP3888971B2 (de)
CN (1) CN1468259A (de)
AT (1) ATE444309T1 (de)
AU (1) AU7921701A (de)
CA (1) CA2418014C (de)
DE (1) DE60140063D1 (de)
DK (1) DK1309627T3 (de)
WO (1) WO2002012347A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2704600C (en) 1999-04-09 2016-10-25 Kyowa Kirin Co., Ltd. A method for producing antibodies with increased adcc activity
AU2001290801A1 (en) * 2000-09-12 2002-03-26 Zycos Inc. Peptide epitopes recognized by antigen specific cd4+ t lymphocytes
US6946292B2 (en) 2000-10-06 2005-09-20 Kyowa Hakko Kogyo Co., Ltd. Cells producing antibody compositions with increased antibody dependent cytotoxic activity
WO2003050257A2 (en) * 2001-12-06 2003-06-19 University Of Florida Targeting leukemia cells
CA2481304A1 (en) * 2002-03-27 2003-10-09 Patrick Hwu Method for treating cancer in humans
US7541440B2 (en) * 2002-09-30 2009-06-02 Immunomedics, Inc. Chimeric, human and humanized anti-granulocyte antibodies and methods of use
WO2004043461A1 (en) * 2002-11-06 2004-05-27 Wyeth Combination therapy for the treatment of acute leukemia and myelodysplastic syndrome
ZA200503075B (en) 2002-11-07 2006-09-27 Immunogen Inc Anti-CD33 antibodies and method for treatment of acute myeloid leukemia using the same
EP2322547A1 (de) 2003-06-25 2011-05-18 Crucell Holland B.V. Myeloidzellen-spezifisches Lectin
US7939058B2 (en) 2003-07-03 2011-05-10 University Of Southern California Uses of IL-12 in hematopoiesis
JPWO2005053741A1 (ja) * 2003-12-04 2007-06-28 協和醗酵工業株式会社 ケモカイン受容体ｃｃｒ４に対する遺伝子組換え抗体を含む医薬
WO2005102456A1 (en) * 2004-03-27 2005-11-03 The Arizona Board Of Regents On Behalf Of The University Of Arizona Composition and method for cancer treatment
WO2006050075A2 (en) * 2004-10-29 2006-05-11 Regents Of The University Of California Method of increasing efficacy of tumor cell killing using combinations of anti-neoplastic agents
US20060234959A1 (en) * 2005-04-14 2006-10-19 Advanced Photodynamic Technologies, Inc. Photodynamic therapy utilizing multiple duty cycle light modulation
US20060257317A1 (en) * 2005-05-04 2006-11-16 Duke University Combination therapy in the treatment of cancer
PT1962913E (pt) 2005-11-30 2014-01-30 Therapharm Gmbh Radioimunoconjugado para cd66 humano para o tratamento de mieloma múltiplo
WO2008029271A2 (en) 2006-02-27 2008-03-13 Gal Markel Ceacam based antibacterial agents
BRPI0710650A2 (pt) * 2006-04-13 2011-08-23 Medical And Biological Laboratories Co., Ltd células parceiras de fusão
AU2007317333A1 (en) * 2006-11-02 2008-05-15 Seattle Genetics, Inc. Methods of treating neoplastic, autoimmune and inflammatory diseases
EP2478110B1 (de) 2009-09-16 2016-01-06 Immunomedics, Inc. Klasse-i-anti-cea-antikörper und verwendungen davon
US20130309223A1 (en) 2012-05-18 2013-11-21 Seattle Genetics, Inc. CD33 Antibodies And Use Of Same To Treat Cancer
MX338711B (es) 2012-10-12 2016-04-28 Medimmune Ltd Pirrolobenzodiazepinas y conjugados de las mismas.
TWI680766B (zh) 2013-03-13 2020-01-01 英商梅迪繆思有限公司 吡咯并苯并二氮呯及其共軛物
AU2014229529B2 (en) 2013-03-13 2018-02-15 Medimmune Limited Pyrrolobenzodiazepines and conjugates thereof
MX362970B (es) 2013-03-13 2019-02-28 Medimmune Ltd Pirrolobenzodiazepinas y conjugados de las mismas.
EP3193940A1 (de) 2014-09-10 2017-07-26 Medimmune Limited Pyrrolobenzodiazepine und konjugate daraus
WO2017160954A1 (en) 2016-03-15 2017-09-21 Seattle Genetics, Inc. Combinations of pbd-based antibody drug conjugates with bcl-2 inhibitors
WO2017210621A1 (en) 2016-06-03 2017-12-07 Seattle Genetics, Inc. Combination of cd33 antibody drug conjugates with chemotherapeutic agents
WO2017214433A1 (en) 2016-06-09 2017-12-14 Seattle Genetics, Inc. Combinations of pbd-based antibody drug conjugates with flt3 inhibitors
EP3525829A1 (de) 2016-10-11 2019-08-21 Medimmune Limited Antikörper-wirkstoffkonjugate mit immunvermittelten therapiemitteln
CA3098103A1 (en) 2018-05-23 2019-11-28 Adc Therapeutics Sa Molecular adjuvant
US20230372528A1 (en) 2020-10-16 2023-11-23 University Of Georgia Research Foundation, Inc. Glycoconjugates
GB202102396D0 (en) 2021-02-19 2021-04-07 Adc Therapeutics Sa Molecular adjuvant
EP4426727A2 (de) 2021-11-03 2024-09-11 Hangzhou Dac Biotech Co., Ltd. Spezifische konjugation eines antikörpers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4904596A (en) * 1985-08-07 1990-02-27 Fred Hutchinson Cancer Research Center Hybridoma antibody (FH6) defining a human cancer-associated difucoganglioside
TR200002243T2 (tr) * 1997-11-10 2000-12-21 Memorial Sloan-Kettering Cancer Center Arsenik trioksitin hazırlanması için işlem ve bunların kanser tedavisi için kullanımı.
CA2279474C (en) * 1998-07-31 2011-01-04 Stemcell Technologies Inc. Novel antibody composition for debulking blood and bone marrow samples from cml patients

Also Published As

Publication number Publication date
CN1468259A (zh) 2004-01-14
WO2002012347A1 (en) 2002-02-14
US6759045B2 (en) 2004-07-06
EP1309627A1 (de) 2003-05-14
US7323168B2 (en) 2008-01-29
JP2004505994A (ja) 2004-02-26
CA2418014A1 (en) 2002-02-14
JP3888971B2 (ja) 2007-03-07
AU2001279217C1 (en) 2002-02-18
EP1309627B1 (de) 2009-09-30
AU7921701A (en) 2002-02-18
CA2418014C (en) 2014-01-21
US20040213796A1 (en) 2004-10-28
DK1309627T3 (da) 2009-12-21
US20020022031A1 (en) 2002-02-21
DE60140063D1 (de) 2009-11-12

Similar Documents

Publication Publication Date Title
ATE444309T1 (de) Immuntherapie für kronische myelozytische leukämie mit nacktem anti-nca-90 antikörper
MXPA05005726A (es) Metodos y composiciones para inducir apoptosis en celulas de cancer.
MA42999B1 (fr) Polythérapie contenant ivosidenib, cytarabine et daunorubicin ou idarubicin pour le traitement de la leucémie myéloïde aiguë
MX2021007350A (es) Terapia combinada de cd70 y venetoclax, un inhibidor de bcl-2, para tratar la leucemia mieloide aguda.
CL2007001624A1 (es) Uso de un anticuerpo que se une a dll4 para el tratamiento de tumor, cancer o trastorno de proliferacion celular.
CL2012000519A1 (es) Uso de un anticuerpo aislado o fragmento de enlace antígeno del mismo que comprende una región variable de cadena ligera y una de cadena pesada (sec nº38 y nº40) útil en el tratamiento y prevención de carcinoma de células escamosas en un mamífero (div. sol. 3615-07).
SG160412A1 (en) Anti-igfr1 antibody therapeutic combinations
TW200612918A (en) Lonidamine analogs
HUP0300590A2 (hu) Peptidázzal hasítható, célzott antineoplasztikus szerek és terápiás alkalmazásuk
IL184617A (en) Antibody against dr5 that includes mutations in the heavy and light chain of the full-length antibody 16e2 and various aspects related to this antibody
IL214325A (en) Antibody against cmet, a drug that includes and uses it
DK1187632T3 (da) Behandling med anti-ErbB2-antistoffer
AR045179A1 (es) Uso de una combinacion de un inhibidor de la quinasa del receptor del factor de crecimiento epidermico y de agentes citotoxicos para el tratamiento e inhibicion del cancer
MA43000B1 (fr) Polythérapie pour le traitement de tumeurs malignes
AR052774A1 (es) Inmunoterapia para trastornos autoinmunes
AR023616A1 (es) Preparaciones combinadas que comprenden derivados de antraciclina
BR0306820A (pt) Uso de inibidores cox-2 em combinação com agentes antivirais para o tratamento de infecções de papilomavìrus
BR0213424A (pt) Uso aperfeiçoado de composto antitumoral na terapia contra câncer
WO2008112129A3 (en) Treatment of carcinomas with a combination of egf-pathway and telomerase inhibitors
MX2009010269A (es) Metodos de tratamiento del cancer mediante administracion de combinaciones de interleucina-18 humana.
ATE424461T1 (de) Modifizierte zytokine für krebs therapie
IL141550A0 (en) Methods and compositions for the prevention or treatment of cancer
WO2008066854A3 (en) Methods and compositions for inducing apoptosis in cancer cells
AU2021334165A8 (en) Method of treatment of patients having reduced sensitivity to a BCL-2 inhibitor
ATE509630T1 (de) Pankreaskrebsbehandlung mit na+/k+-atpase-hemmern

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties