ATE444969T1 - Dimerisiertes peptid - Google Patents

Dimerisiertes peptid

Info

Publication number
ATE444969T1
ATE444969T1 AT04702444T AT04702444T ATE444969T1 AT E444969 T1 ATE444969 T1 AT E444969T1 AT 04702444 T AT04702444 T AT 04702444T AT 04702444 T AT04702444 T AT 04702444T AT E444969 T1 ATE444969 T1 AT E444969T1
Authority
AT
Austria
Prior art keywords
peptide
tumor antigen
dimerized peptide
antigen peptide
dimerized
Prior art date
Application number
AT04702444T
Other languages
English (en)
Inventor
Hideo Takasu
Fumio Samizo
Haruo Sugiyama
Original Assignee
Int Inst Cancer Immunology Inc
Chugai Pharmaceutical Co Ltd
Dainippon Sumitomo Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Int Inst Cancer Immunology Inc, Chugai Pharmaceutical Co Ltd, Dainippon Sumitomo Pharma Co filed Critical Int Inst Cancer Immunology Inc
Application granted granted Critical
Publication of ATE444969T1 publication Critical patent/ATE444969T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82Translation products from oncogenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT04702444T 2003-01-15 2004-01-15 Dimerisiertes peptid ATE444969T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003007122 2003-01-15
PCT/JP2004/000254 WO2004063217A1 (ja) 2003-01-15 2004-01-15 二量体化ペプチド

Publications (1)

Publication Number Publication Date
ATE444969T1 true ATE444969T1 (de) 2009-10-15

Family

ID=32709100

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04702444T ATE444969T1 (de) 2003-01-15 2004-01-15 Dimerisiertes peptid

Country Status (12)

Country Link
US (2) US20060217297A1 (de)
EP (2) EP2154145B1 (de)
JP (2) JP4498274B2 (de)
KR (2) KR20120054644A (de)
CN (2) CN101851275A (de)
AT (1) ATE444969T1 (de)
AU (1) AU2004204031B2 (de)
BR (1) BRPI0406800B8 (de)
CA (1) CA2513701C (de)
DE (1) DE602004023476D1 (de)
ES (1) ES2332590T3 (de)
WO (1) WO2004063217A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4932199A (en) * 1998-07-31 2000-02-21 Haruo Sugiyama Cancer antigens based on tumor suppressor gene wt1 product
EP1371664B1 (de) * 2001-03-22 2008-01-09 International Institute of Cancer Immunology, Inc. Wti-modifiziertes peptid
CA2448109A1 (en) * 2001-05-25 2002-12-05 Thomas Jefferson University Alternative splice forms of proteins as basis for multiple therapeutic modalities
WO2004024175A1 (ja) * 2002-09-12 2004-03-25 Haruo Sugiyama 癌抗原ペプチド製剤
KR101213015B1 (ko) 2003-11-05 2012-12-26 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 Wt1 로부터 유도된 hla-dr 결합성 항원 펩티드
PT1731605E (pt) * 2004-03-31 2010-04-14 Int Inst Cancer Immunology Inc Péptidos antigénicos de cancro derivados de wt1
ES2523172T3 (es) * 2005-02-04 2014-11-21 Survac Aps Vacuna de péptido de survivina
CA2631292C (en) 2005-11-30 2014-05-06 International Institute Of Cancer Immunology, Inc. Derivatised wt1 cancer antigen peptides and their use
AU2007218649B2 (en) 2006-02-22 2013-01-10 International Institute Of Cancer Immunology, Inc. HLA-A*3303-restricted WT1 peptide and pharmaceutical composition comprising the same
ZA200807027B (en) * 2006-02-23 2009-12-30 Fibrex Medical Res & Dev Gmbh Peptides and peptide derivatives, the production thereof as well as their use for preparing a therapeutically and/or preventively active pharmaceutical composition
EP2341142B8 (de) 2006-12-28 2015-01-14 International Institute of Cancer Immunology, Inc. HLA-A*1101-beschränktes WT1-Peptid und pharmazeutische Zusammensetzung damit
BRPI0808084A2 (pt) 2007-02-27 2014-07-22 Int Inst Cancer Immunology Inc Método para ativação de células t auxiliadoras e composição para uso no método.
DK2193142T3 (da) * 2007-08-30 2015-04-20 Curedm Group Holdings Llc Præparater og fremgangsmåder til anvendelse af pro-øcellepeptider og analoger dertil
KR20140009168A (ko) 2010-10-05 2014-01-22 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 헬퍼 t 세포의 활성화 방법
EP2646459B1 (de) 2010-12-02 2020-01-08 Bionor Immuno AS Peptidgerüstentwurf
MX2013007146A (es) * 2010-12-23 2013-11-01 Intercell Austria Ag Agentes de proteina f/i de membrana externa (oprf/i) y su uso en pacientes hospitalizados y otros pacientes.
JP6294076B2 (ja) 2011-01-06 2018-03-14 ビオノール イミュノ エーエスBionor Immuno As 多量体ペプチド
JP6082901B2 (ja) * 2011-01-31 2017-02-22 オリンパス株式会社 ワクチン・アジュバント
JP6163486B2 (ja) 2012-07-02 2017-07-12 大日本住友製薬株式会社 癌抗原ペプチド経皮剤
SG10201705028WA (en) 2012-12-17 2017-07-28 Otsuka Pharma Co Ltd Method for activating helper t cell
EP2974734B1 (de) 2013-03-12 2018-10-10 Sumitomo Dainippon Pharma Co., Ltd. Flüssige, wässrige zusammensetzung
SG11201507883SA (en) * 2013-03-29 2015-10-29 Sumitomo Dainippon Pharma Co Ltd Wt1-antigen peptide conjugate vaccine
WO2014157704A1 (ja) 2013-03-29 2014-10-02 大日本住友製薬株式会社 Erap1によるトリミング機能をきっかけとしたコンジュゲートワクチン
KR20160063349A (ko) 2013-10-17 2016-06-03 서울대학교산학협력단 알파나선형 세포 투과 펩타이드 다합체,이의 제조방법 및 그 용도
ES2916834T3 (es) * 2014-09-27 2022-07-06 Sumitomo Pharma Co Ltd Composición farmacéutica para inyección
JP6671141B2 (ja) * 2014-10-21 2020-03-25 大日本住友製薬株式会社 懸濁液剤
CN107921106B (zh) * 2015-05-20 2023-09-08 住友制药株式会社 Wt1抗原肽和免疫调节剂的组合用途
ES3038398T3 (en) 2015-07-14 2025-10-13 Yeda Res & Dev Peptide combinations for use in the diagnosis of schizophrenia
US12383608B2 (en) 2016-11-30 2025-08-12 Sumitomo Pharma Co., Ltd. WT1 helper peptides and combinations of WT1 helper peptide and conjugate of cancer antigen peptides
US20200368338A1 (en) * 2017-12-27 2020-11-26 Sumitomo Dainippon Pharma Co., Ltd. Conjugate of wt1-derived peptides and composition comprising the same
US12233130B2 (en) 2022-12-22 2025-02-25 Defence Therapeutics Inc. Covalently-modified steroid acid-peptides having enhanced stability and/or biological activity

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6034235A (en) * 1995-06-01 2000-03-07 Tadamitsu Kishimoto Growth inhibitor for leukemia cell comprising antisense oligonucleotide derivative to wilms tumor gene (WT1)
JP3060287B2 (ja) 1995-10-09 2000-07-10 参天製薬株式会社 アパファントを主薬とする水性点眼剤
AU4932199A (en) 1998-07-31 2000-02-21 Haruo Sugiyama Cancer antigens based on tumor suppressor gene wt1 product
US7063854B1 (en) * 1998-09-30 2006-06-20 Corixa Corporation Composition and methods for WTI specific immunotherapy
AR021849A1 (es) * 1998-09-30 2002-08-07 Corixa Corp Composiciones y metodos para la inmunoterapia especifica de wt1
GB9823897D0 (en) * 1998-11-02 1998-12-30 Imp College Innovations Ltd Immunotherapeutic methods and molecules
WO2002047474A1 (en) 2000-12-13 2002-06-20 Sumitomo Pharmaceuticals Company, Limited Transgenic animal expressing hla-a24 and utilization thereof
EP1371664B1 (de) * 2001-03-22 2008-01-09 International Institute of Cancer Immunology, Inc. Wti-modifiziertes peptid
JP5230891B2 (ja) * 2001-09-28 2013-07-10 株式会社癌免疫研究所 抗原特異的t細胞の新規な誘導方法
US20050002951A1 (en) * 2001-09-28 2005-01-06 Haruo Sugiyama Novel method of inducing antigen-specific t cells
WO2003106682A1 (ja) * 2002-06-12 2003-12-24 中外製薬株式会社 Hla−a24拘束性癌抗原ペプチド
KR101213015B1 (ko) 2003-11-05 2012-12-26 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 Wt1 로부터 유도된 hla-dr 결합성 항원 펩티드
PT1731605E (pt) 2004-03-31 2010-04-14 Int Inst Cancer Immunology Inc Péptidos antigénicos de cancro derivados de wt1

Also Published As

Publication number Publication date
BRPI0406800A (pt) 2006-01-17
KR20120054644A (ko) 2012-05-30
CA2513701A1 (en) 2004-07-29
KR20050098863A (ko) 2005-10-12
DE602004023476D1 (de) 2009-11-19
EP1584627A1 (de) 2005-10-12
ES2332590T3 (es) 2010-02-09
US8242084B2 (en) 2012-08-14
CA2513701C (en) 2013-06-18
EP2154145A2 (de) 2010-02-17
JP2010047603A (ja) 2010-03-04
JP4498274B2 (ja) 2010-07-07
CN1756763A (zh) 2006-04-05
EP1584627B1 (de) 2009-10-07
BRPI0406800B1 (pt) 2020-08-11
EP2154145B1 (de) 2013-04-24
CN1756763B (zh) 2010-05-26
BRPI0406800A8 (pt) 2016-11-01
BRPI0406800B8 (pt) 2021-05-25
CN101851275A (zh) 2010-10-06
EP2154145A3 (de) 2010-05-19
JPWO2004063217A1 (ja) 2006-06-01
JP4926231B2 (ja) 2012-05-09
US20060217297A1 (en) 2006-09-28
US20100292164A1 (en) 2010-11-18
AU2004204031B2 (en) 2010-03-04
AU2004204031A1 (en) 2004-07-29
WO2004063217A1 (ja) 2004-07-29
EP1584627A4 (de) 2006-03-15
HK1081975A1 (en) 2006-05-26
HK1141539A1 (en) 2010-11-12
KR101399678B1 (ko) 2014-05-27

Similar Documents

Publication Publication Date Title
ATE444969T1 (de) Dimerisiertes peptid
CY1118037T1 (el) Αντισωματα εναντι του αβητα και h χρηση τους
WO2007064919A3 (en) Binding polypeptides with restricted diversity sequences
CY1119106T1 (el) Αντισωματα εναντι masp-2
WO2003102157A3 (en) Synthetic antibody phage libraries
ATE415413T1 (de) Iap-bindende verbindungen
CY1113850T1 (el) Νεα παραγωγα ινσουλινης
NO20075927L (no) IL-21 varianter
WO2005012531A3 (en) Antibody cdr polypeptide sequences with restricted diversity
DK1423419T3 (da) Hybrid- og tandemekspression af Neisseria-proteiner
CY1108960T1 (el) Αντισωματα αποκλεισμου cripto και οι χρησεις τους
CY1114050T1 (el) Μονοκλωνικα αντισωματα εναντι claudin-18 στην αγωγη εναντι καρκινου
ATE545703T1 (de) Multivalentes zielbindendes protein
DE60232577D1 (de) Oligomerische komplexe von chimären proteinen mit verbessertem immunogenen potential
EP1731605A4 (de) Aus wt1 stammende krebsantigenpeptide
ATE542137T1 (de) Immunocytokine mit modulierter selektivität
DK1144607T3 (da) Fremgangsmåde til præsentation af (poly)peptider/proteiner på bakteriofage partikler via disulfidbindinger
ATE404225T1 (de) Radiofluorierte peptide
DE502004011395D1 (de) Protein-bindende doxorubicin-peptid-derivate
PE20050962A1 (es) Anticuerpos completamente humanos contra 4-1bb humano
EP2305710A3 (de) Synthetische Antikörperphagenbibliotheken
EA200600042A1 (ru) Способы образования дисульфидных связей и гликозилирования белков и реагенты, применяемые в этих способах
ATE419861T1 (de) Peptide mit homing für lymphgefässtumor und ihre verwendung
ATE467421T1 (de) Cytokine und cytokinrezeptoren mit reduzierter immunogenität
ATE470678T1 (de) Emitter-bindende peptide, die eine veränderung der spektralen emissionseigenschaften des emitters bewirken

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties