ATE446513T1 - Verfahren zum electrochemischen analysieren einer analyte - Google Patents

Verfahren zum electrochemischen analysieren einer analyte

Info

Publication number
ATE446513T1
ATE446513T1 AT99940398T AT99940398T ATE446513T1 AT E446513 T1 ATE446513 T1 AT E446513T1 AT 99940398 T AT99940398 T AT 99940398T AT 99940398 T AT99940398 T AT 99940398T AT E446513 T1 ATE446513 T1 AT E446513T1
Authority
AT
Austria
Prior art keywords
analyte
sensing electrode
electrochemically analyzing
specific
immobilised
Prior art date
Application number
AT99940398T
Other languages
English (en)
Inventor
Dmitri Alexandrovich Farmakovski
Yevgeni Yurevich Milanovski
Vladimir Rurikovich Cherkasov
Yuri Sergeyevich Biryukov
Olga Leonardova
Original Assignee
Sensortec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sensortec Ltd filed Critical Sensortec Ltd
Application granted granted Critical
Publication of ATE446513T1 publication Critical patent/ATE446513T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT99940398T 1998-08-24 1999-08-24 Verfahren zum electrochemischen analysieren einer analyte ATE446513T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU98116346/13A RU2161653C2 (ru) 1998-08-24 1998-08-24 Способ количественного электрохимического анализа биомолекул
PCT/GB1999/002785 WO2000011473A1 (en) 1998-08-24 1999-08-24 Method of electrochemical analysis of an analyte

Publications (1)

Publication Number Publication Date
ATE446513T1 true ATE446513T1 (de) 2009-11-15

Family

ID=20210003

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99940398T ATE446513T1 (de) 1998-08-24 1999-08-24 Verfahren zum electrochemischen analysieren einer analyte

Country Status (10)

Country Link
US (1) US6770190B1 (de)
EP (1) EP1108213B1 (de)
JP (1) JP4774150B2 (de)
CN (1) CN1135390C (de)
AT (1) ATE446513T1 (de)
AU (1) AU5437999A (de)
DE (1) DE69941572D1 (de)
GB (1) GB2347223B (de)
RU (1) RU2161653C2 (de)
WO (1) WO2000011473A1 (de)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002525590A (ja) 1998-08-28 2002-08-13 フェビット フェラリウス バイオテクノロジー ゲゼルシャフト ミット ベシュレンクテル ハフツング 分析物測定法のための支持体および該支持体を製造する方法
US7034660B2 (en) * 1999-02-26 2006-04-25 Sri International Sensor devices for structural health monitoring
AU1241901A (en) * 1999-11-24 2001-06-04 Biotronics Technologies, Inc. Devices and methods for detecting analytes using electrosensor having capture reagent
DE10022750A1 (de) * 2000-05-10 2001-11-22 Wolfgang Schuhmann Verfahren zur Immobilisierung von Erkennungskomponenten
DE10051396A1 (de) 2000-10-17 2002-04-18 Febit Ferrarius Biotech Gmbh Verfahren und Vorrichtung zur integrierten Synthese und Analytbestimmung an einem Träger
US6670131B2 (en) 2000-11-30 2003-12-30 Kabushiki Kaisha Toshiba Nucleic acid detection method and apparatus, and vessel for detecting nucleic acid
JP4739579B2 (ja) * 2001-06-25 2011-08-03 独立行政法人産業技術総合研究所 内分泌攪乱物質の高感度検出方法、及びこれを適用した内分泌攪乱物質の高感度検出装置
JP4567333B2 (ja) 2001-08-24 2010-10-20 センサーテック・リミテッド 高感度電位差測定センサを製造する方法
US6856125B2 (en) * 2001-12-12 2005-02-15 Lifescan, Inc. Biosensor apparatus and method with sample type and volume detection
DE10204652B4 (de) * 2002-02-05 2004-07-22 Infineon Technologies Ag Schaltkreis-Anordnung, elektrochemischer Sensor, Sensor-Anordnung und Verfahren zum Verarbeiten eines über eine Sensor-Elektrode bereitgestellten Stromsignals
GB0205455D0 (en) 2002-03-07 2002-04-24 Molecular Sensing Plc Nucleic acid probes, their synthesis and use
US6987164B2 (en) * 2002-03-09 2006-01-17 Samsung Electronics Co., Ltd. Electrically conductive polymer, sensor using the same, and method for detecting target molecule using the sensor
DE10211900A1 (de) * 2002-03-18 2003-10-16 Infineon Technologies Ag Biosensor zum Erfassen von makromolekularen Biopolymeren und Verfahren zur Herstellung eines Biosensors zum Erfassen von makromolekularen Biopolymeren
US20030180814A1 (en) * 2002-03-21 2003-09-25 Alastair Hodges Direct immunosensor assay
GB2386950A (en) * 2002-03-26 2003-10-01 Sensor Tech Ltd A sensing electrode for analysis/detection of an analyte in a test sample
DE10224567B4 (de) * 2002-06-03 2014-10-23 Boehringer Ingelheim Vetmedica Gmbh Sensor-Anordnung und Verfahren zum Betreiben einer Sensor-Anordnung
DE10228260A1 (de) * 2002-06-25 2004-01-22 Bayer Ag Methode und Vorrichtung zum impedimetrischen Nachweis eines oder mehrerer Analyten in einer Probe
FR2847581B1 (fr) * 2002-11-21 2007-03-23 Commissariat Energie Atomique Procede de fixation d'une proteine sur un polymere a base de pyrrole et son utilisation pour la fabrication d'un capteur
CN1217192C (zh) * 2002-11-21 2005-08-31 北京博奥生物芯片有限责任公司 光电化学标记物和用其进行光电化学分析的方法、仪器与试剂盒
CN100392385C (zh) * 2002-12-03 2008-06-04 博奥生物有限公司 亲和反应的化学放大电化学检测方法及其试剂盒
DE10319155B4 (de) 2003-04-29 2008-02-14 Bruker Daltonik Gmbh Elektrisch auslesbare Bindungen von Analytmolekülen an immobilisierten Sondenmolekülen
DE10324912A1 (de) 2003-05-30 2005-01-05 Siemens Ag Verfahren zur Detektion von DNA-Punktmutationen (SNP-Analyse) sowie zugehörige Anordnung
KR100549227B1 (ko) * 2003-09-06 2006-02-03 한국전자통신연구원 유기분자 소자의 제작 방법
JP4497903B2 (ja) * 2003-12-02 2010-07-07 財団法人大阪産業振興機構 タンパク質チップおよびそれを用いたバイオセンサー
RU2266959C2 (ru) * 2004-01-15 2005-12-27 Сорокин Виктор Фёдорович Способ получения биосенсоров (варианты)
DE102004005710A1 (de) 2004-02-05 2006-05-04 Siemens Ag Biosensor und Verfahren zu dessen Betrieb
DE102004005711A1 (de) * 2004-02-05 2006-05-11 Siemens Ag Biosensor zur Bestimmung eines Allergenes mit Betriebsverfahren
JP2006133137A (ja) * 2004-11-08 2006-05-25 Eiichi Tamiya 被検物質の検出方法
JP4744910B2 (ja) * 2004-11-11 2011-08-10 株式会社堀場製作所 バイオセンサ、マルチバイオセンサ及びこれを用いた多成分測定システム
GB2420180A (en) * 2004-11-11 2006-05-17 Sensor Tech Ltd Method of electrochemical analysis of an analyte
JP4232108B2 (ja) 2005-05-20 2009-03-04 セイコーエプソン株式会社 標的物質の検出または定量方法、該方法に用いられる電極基板、装置、およびキット
US8117902B2 (en) * 2005-11-03 2012-02-21 University Of Massachusetts Nanopatterned surfaces and related methods for selective adhesion, sensing and separation
US20070202561A1 (en) * 2006-02-10 2007-08-30 Becton Dickinson And Company Electronic Detection Immunoassays that Utilize a Binder Support Medium
WO2007106936A1 (en) * 2006-03-17 2007-09-27 Newsouth Innovations Pty Limited Electrochemical sensor
US20080103064A1 (en) * 2006-06-13 2008-05-01 Antara Biosciences Inc. Microscale fluidic devices for electrochemical detection of biological molecules
CN101479604B (zh) * 2006-06-30 2016-06-01 Jnc株式会社 检测对象的检测、定量用试剂盒及检测、定量方法
JP4936536B2 (ja) * 2006-07-13 2012-05-23 国立大学法人富山大学 定量・定性分析方法
EP2061572A1 (de) * 2006-08-31 2009-05-27 Technion Research & Development Foundation Ltd. Steuerbare bindung und dissoziation von chemischen entitäten und elektrodenvorrichtungen dafür
US9018019B2 (en) * 2006-10-04 2015-04-28 President And Fellows Of Harvard College Engineered conductive polymer films to mediate biochemical interactions
JP4751302B2 (ja) * 2006-11-21 2011-08-17 株式会社日立製作所 電位差式センサ及び分析用素子
WO2008112653A1 (en) * 2007-03-09 2008-09-18 Dxtech, Llc Electrochemical detection system
US8197650B2 (en) * 2007-06-07 2012-06-12 Sensor Innovations, Inc. Silicon electrochemical sensors
WO2009052422A1 (en) * 2007-10-17 2009-04-23 Ohmx Corporation Electrochemical assay for the detection of enzymes
US8951400B2 (en) 2007-10-17 2015-02-10 Ohmx Corporation Chemistry used in biosensors
CN101464424B (zh) * 2007-12-18 2013-02-13 宁波大学 一种研究dna分子导电性的测试方法及其测试系统
CN102854232B (zh) * 2008-12-08 2015-12-02 拜尔健康护理有限责任公司 具有信号调节功能的生物传感器系统
US8025789B2 (en) * 2008-12-17 2011-09-27 General Electric Company Anionically-charged polymer detection method
EP2462238B1 (de) * 2009-08-07 2013-07-17 Ohmx Corporation Enzyme-gesteuerter redox-ändernder chemischer eliminierungs- (e-trace-) immunassay
WO2011057347A1 (en) 2009-11-12 2011-05-19 Tgr Biosciences Pty Ltd Analyte detection
GB2476057B (en) * 2009-12-09 2012-05-30 Schlumberger Holdings Electro-chemical sensor
ES2410754T3 (es) * 2010-05-25 2013-07-03 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Procedimiento para la detección electroquímica de reacciones de unión
GB2500550A (en) 2010-12-16 2013-09-25 Sensor Innovations Inc Electrochemical sensors
KR101274854B1 (ko) 2010-12-23 2013-06-13 한남대학교 산학협력단 감염성 호흡기 질환 진단용 전기화학 ｄｎａ 센서 및 이의 제조방법
WO2012100078A1 (en) 2011-01-19 2012-07-26 Ohmx Corporation Enzyme triggered redox altering chemical elimination (e-trace) immmunoassay
CN103459583B (zh) * 2011-03-08 2015-11-25 公立大学法人大阪府立大学 传感器、传感器的制造方法及聚合物层
EP2786150B1 (de) 2011-03-31 2018-08-22 TGR Biosciences Pty Ltd Nachweis mehrerer analyte
RU2466680C1 (ru) 2011-10-03 2012-11-20 Общество С Ограниченной Ответственностью "Витацел" Способ диагностики состояния кожи пациента (варианты)
JP6203183B2 (ja) 2011-10-17 2017-09-27 オームクス コーポレイション 酵素誘発レドックス変化化学的脱離（ｅ−ｔｒａｃｅ）イムノアッセイを使用する、ヘモグロビンａ１ｃのパーセンテージの単回直接検出
JP2014532720A (ja) 2011-11-04 2014-12-08 オームクス コーポレイション バイオセンサーにおいて使用される新規化学
JP6276706B2 (ja) 2012-01-09 2018-02-07 オームクス コーポレイション Ｅ−ｔｒａｃｅアッセイシグナル増幅の酵素カスケード方法
WO2014018899A1 (en) 2012-07-27 2014-01-30 Ohmx Corporation Electric measurement of monolayers following pro-cleave detection of presence and activity of enzymes and other target analytes
EP3121288A1 (de) 2012-07-27 2017-01-25 Ohmx Corporation Elektronische messungen von monoschichten nach homogenen reaktionen ihrer komponenten
CN102875623B (zh) * 2012-09-19 2016-01-20 华东理工大学 糖基蒽醌类化合物及其石墨烯传感器构建
CN102901822A (zh) * 2012-10-23 2013-01-30 扬州大学 聚合物自组装超微孔膜免疫组合传感器的制备方法
WO2014118543A2 (en) * 2013-01-30 2014-08-07 Vantix Holdings Limited Electrochemical total protein detection system
EP2972333B1 (de) 2013-03-11 2018-09-19 The University of Toledo Biosensorvorrichtung zur abzielung auf analyten in situ, in vivo, und/oder in echtzeit und verfahren zur herstellung und verwendung davon
US9594047B2 (en) * 2013-04-26 2017-03-14 Universiteit Antwerpen Potentiometric sensors and method for measuring intermolecular interactions
DE102013211837A1 (de) * 2013-06-21 2014-12-24 Gilupi Gmbh Katheter mit Detektionsvorrichtung zum Echtzeitnachweis eines Probenmaterials
JP5565783B1 (ja) * 2013-08-08 2014-08-06 国立大学法人 東京大学 バイオセンサ
JP5599012B1 (ja) * 2014-06-23 2014-10-01 国立大学法人 東京大学 採取部及びバイオセンサ
WO2016043078A1 (ja) * 2014-09-19 2016-03-24 国立大学法人 新潟大学 基質抗原同時検出バイオセンサ、電極、基質抗原同時検出方法、および、プログラム
EP3078965B1 (de) * 2015-04-06 2018-04-04 ARKRAY, Inc. Biosensor mit elektrode zur messung des hämatokritwertes
CN105353015B (zh) * 2015-12-02 2019-04-12 厦门大学 一种聚二氧乙烯噻吩复合膜的制备方法及应用
CN105606675B (zh) * 2015-12-30 2018-09-18 湖南大学 用于检测铅的适配体传感器及其制备方法和应用
US10791972B2 (en) 2017-04-21 2020-10-06 2Pi-Sigma Corporation Fluid measurement for automated medical sample collection and testing
US11175303B2 (en) 2017-04-21 2021-11-16 2Pi-Sigma Corp. Automated medical sample collection and testing for providing blood coagulation indication
US11202593B2 (en) 2017-04-21 2021-12-21 2Pi-Sigma Corp. Adjustable lancet and test cartridge for automated medical sample collection and testing
US11103163B2 (en) 2017-04-21 2021-08-31 2Pi-Sigma Corporation Test cartridge and lancet for automated medical sample collection and testing
US10928411B2 (en) 2017-04-21 2021-02-23 2Pi-Sigma Corporation Automated medical sample collection and testing
WO2018195544A1 (en) * 2017-04-21 2018-10-25 2Pi-Sigma Corporation Automated medical sample collection, testing, and analysis
CN106979966A (zh) * 2017-05-09 2017-07-25 福建医科大学附属协和医院 一种检测纤维连接蛋白的电化学免疫传感器的制备方法
US12153010B2 (en) 2018-04-17 2024-11-26 Korea Research Institute Of Chemical Technology Multiwell electrode-based biosensor
KR20210045361A (ko) 2018-05-17 2021-04-26 레커그니션 어낼러틱스 엘엘씨 효소 활성의 직접 전기적 측정을 위한 장치, 시스템 및 방법
EP3578665B1 (de) * 2018-05-22 2024-02-21 ARKRAY, Inc. Biosensing-verfahren
WO2019226464A1 (en) * 2018-05-22 2019-11-28 Strella Biotechnology Company Ethylene receptor biosensor
CN111351938A (zh) * 2018-12-20 2020-06-30 麦德龙生物株式会社 电激发标记分子的方法和绝缘膜涂覆的电极
US12351855B2 (en) * 2019-01-30 2025-07-08 Arizona Board Of Regents On Behalf Of Arizona State University Bioelectronic circuits, systems and methods for preparing and using them
CN110376380B (zh) * 2019-07-25 2020-07-24 华中科技大学 一种电化学酶联免疫传感器及其制备与检测抗原的应用
IL297732A (en) 2020-04-30 2022-12-01 Univ Arizona State Methods for sequencing biopolymers
DE102021117034B4 (de) * 2021-07-01 2024-02-01 Hexagonfab System mit roboteraktuator zum eintauchen eines elektrischen sensors zum messen von eigenschaften von molekülen
CN114441614A (zh) * 2021-12-30 2022-05-06 广州市赛特检测有限公司 一种电化学微生物快速检测仪及生物探针的修饰方法
JP7709140B2 (ja) * 2022-03-01 2025-07-16 学校法人早稲田大学 小型非荷電分子の検出方法
CN116212987A (zh) * 2022-12-12 2023-06-06 苏州大学 一种液滴运动操控微管及光控液滴运动的方法
WO2024191912A1 (en) * 2023-03-10 2024-09-19 President And Fellows Of Harvard College System for label-free electrochemical sensing

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0697219B2 (ja) 1985-02-25 1994-11-30 財団法人化学及血清療法研究所 免疫センサー用電極及びその製造方法
JPH0721478B2 (ja) * 1986-03-31 1995-03-08 財団法人化学及血清療法研究所 免疫センサ−用作用膜
WO1989011649A1 (en) * 1988-05-16 1989-11-30 Wollongong Uniadvice Limited Antibody containing electrode
JPH02179461A (ja) * 1988-12-30 1990-07-12 Chemo Sero Therapeut Res Inst 酵素免疫センサ用膜
US5312762A (en) * 1989-03-13 1994-05-17 Guiseppi Elie Anthony Method of measuring an analyte by measuring electrical resistance of a polymer film reacting with the analyte
RU2032908C1 (ru) * 1991-04-26 1995-04-10 Институт геохимии и аналитической химии им.В.И.Вернадского РАН Устройство для определения биологически активных соединений в биологических жидкостях и способ изготовления чувствительного элемента
GB2276724A (en) * 1993-03-31 1994-10-05 Cambridge Life Sciences Electrochemical detection of specific binding species
AU2985295A (en) * 1994-07-07 1996-02-09 Dmitri Alexand Farmakovski Electrochemical immunoassay
NZ336910A (en) * 1997-02-06 2001-09-28 Xanthon Inc Electrochemical probes for detection of molecular interactions and drug discovery
RU2107296C1 (ru) * 1997-02-20 1998-03-20 Дмитрий Александрович ФАРМАКОВСКИЙ Способ электрохимической индикации иммунохимически активных макромолекул в исследуемых растворах

Also Published As

Publication number Publication date
GB0012057D0 (en) 2000-07-12
EP1108213B1 (de) 2009-10-21
RU2161653C2 (ru) 2001-01-10
US6770190B1 (en) 2004-08-03
DE69941572D1 (de) 2009-12-03
GB2347223B (en) 2003-03-26
CN1325490A (zh) 2001-12-05
CN1135390C (zh) 2004-01-21
EP1108213A1 (de) 2001-06-20
JP2002523746A (ja) 2002-07-30
JP4774150B2 (ja) 2011-09-14
GB2347223A (en) 2000-08-30
AU5437999A (en) 2000-03-14
WO2000011473A1 (en) 2000-03-02

Similar Documents

Publication Publication Date Title
ATE446513T1 (de) Verfahren zum electrochemischen analysieren einer analyte
WO2003016555A1 (en) Cell diagnosing method, and device and apparatus used for it
ATE266868T1 (de) Methode und vorrichtung zum elektrochemischen immunoassay mehrerer analyten
NZ306051A (en) Testing using electrochemiluminescence
DE60317422D1 (de) Mediator-stabilisierende Verbindung und Methoden zur Verwendung zur Detektion elektrochemischer Analyte
ATE327507T1 (de) Verdrängungstest auf einer porösen membran
SE9602545L (sv) Metod för att diskriminera komplexa biologiska prover
ATE31822T1 (de) Testvorrichtung.
WO2001011354A3 (en) Methods for characterizing, classifying, and identifying unknowns in samples
ATE461450T1 (de) Verwendung von kontrollflächen zur detektion von störproben in einem nachweisverfahren
SG159463A1 (en) Method for detecting biomolecules and use thereof
WO2004019465A3 (en) Ex-situ pem fuel cell testing: towards visualizing gas diffusion
CN202744629U (zh) 一种剥离涂层下缝隙内金属腐蚀试验装置
PT918991E (pt) Metodo de ensaio
DE69919885D1 (de) Verfahren zur messung der zellulären adhäsion
CN100429511C (zh) 一种集成于芯片毛细管电泳的电化学检测方法
DE69930843D1 (de) Verfahren zum bestimmen von autoantikörpern
ATE421093T1 (de) Schnelle bestimmung verschiedener formen von hgf (heptocyte growth factor) in den körperflüssigkeiten
WO2004106929A3 (en) Assay method
ATE274702T1 (de) Verwendung derivatisierter reagenzien in chemilumineszenz- und elektrochemilumineszenz- nachweisverfahren
AU1705801A (en) Dynamic determination of analytes
ATE505730T1 (de) Verfahren zum nachweis einer an einen nukleären rezeptor gebundenen substanz
WO2003076654A3 (de) Verfahren zum nachweisen, quantifizieren und/oder charakterisieren eines analyten

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties