ATE446949T1 - Neues a-liponsäurederivat und dessen verwendung - Google Patents
Neues a-liponsäurederivat und dessen verwendungInfo
- Publication number
- ATE446949T1 ATE446949T1 AT02705321T AT02705321T ATE446949T1 AT E446949 T1 ATE446949 T1 AT E446949T1 AT 02705321 T AT02705321 T AT 02705321T AT 02705321 T AT02705321 T AT 02705321T AT E446949 T1 ATE446949 T1 AT E446949T1
- Authority
- AT
- Austria
- Prior art keywords
- lipomic
- new
- acid derivative
- denotes
- inhibiting activity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001078571 | 2001-03-19 | ||
| PCT/JP2002/002577 WO2002076935A1 (en) | 2001-03-19 | 2002-03-18 | Novel a-lipoic acid derivative and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE446949T1 true ATE446949T1 (de) | 2009-11-15 |
Family
ID=18935167
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02705321T ATE446949T1 (de) | 2001-03-19 | 2002-03-18 | Neues a-liponsäurederivat und dessen verwendung |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7700080B2 (de) |
| EP (1) | EP1371640B1 (de) |
| JP (1) | JP4072062B2 (de) |
| AT (1) | ATE446949T1 (de) |
| DE (1) | DE60234164D1 (de) |
| ES (1) | ES2331832T3 (de) |
| WO (1) | WO2002076935A1 (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8147816B2 (en) * | 2000-08-16 | 2012-04-03 | Encore Health, Llc | Presbyopia treatment by lens alteration |
| US20050112113A1 (en) * | 2000-08-16 | 2005-05-26 | Till Jonathan S. | Presbyopia treatment by lens alteration |
| US7935332B2 (en) * | 2000-08-16 | 2011-05-03 | Encore Health, Llc | Presbyopia treatment by lens alteration |
| US7914815B2 (en) * | 2000-08-16 | 2011-03-29 | Encore Health, Llc | Method for delivery of pharmaceuticals for treating or preventing presbyopia |
| US8697109B2 (en) | 2000-08-16 | 2014-04-15 | Encore Health, Llc | Caged mercaptan and seleno-mercaptan compounds and methods of using them |
| US8647612B2 (en) * | 2008-03-05 | 2014-02-11 | Encore Health, Llc | Dithiol compounds, derivatives, and treatment of presbyopia |
| EP1371640B1 (de) * | 2001-03-19 | 2009-10-28 | Senju Pharmaceutical Co., Ltd. | Neues a-liponsäurederivat und dessen verwendung |
| EP1547590A4 (de) * | 2002-09-13 | 2008-07-30 | Oga Res Inc | Melanin-löscher |
| US8975295B2 (en) * | 2002-10-25 | 2015-03-10 | Precision Dermatology, Inc. | Modulation of zinc levels to improve tissue properties |
| JP2008174453A (ja) * | 2005-04-28 | 2008-07-31 | Iwaki Kk | 頭皮脱毛治療剤 |
| JP2007254423A (ja) * | 2006-03-24 | 2007-10-04 | Dhc Co | シート状パック材及びシート状パック材の品質保持方法 |
| DE102007038849A1 (de) | 2007-08-16 | 2009-02-19 | Adscil Gmbh | Verwendung von R(+)-alpha-Liponsäure zur Behandlung der kryptogenen Neuropathie |
| US8102027B2 (en) * | 2007-08-21 | 2012-01-24 | Broadcom Corporation | IC package sacrificial structures for crack propagation confinement |
| US9044439B2 (en) | 2008-03-05 | 2015-06-02 | Encore Health, Llc | Low dose lipoic and pharmaceutical compositions and methods |
| WO2009111635A2 (en) | 2008-03-05 | 2009-09-11 | Encore Health, Llc | Dithiol compounds, derivatives, and uses therefor |
| JP6227856B2 (ja) | 2008-04-01 | 2017-11-08 | アントイポデアン ファーマシューティカルズ， インコーポレイテッド | スキンケア用組成物及び方法 |
| US7928067B2 (en) | 2009-05-14 | 2011-04-19 | Ischemix Llc | Compositions and methods for treating ischemia and ischemia-reperfusion injury |
| EP3069612A3 (de) * | 2009-06-15 | 2016-10-19 | Encore Health, LLC | Dithiolverbindungen, derivate davon und verwendungen davon |
| EP2821405B1 (de) | 2009-06-15 | 2016-04-13 | Encore Health, LLC | Cholinester zur Behandlung von Presbyopie und Katarakt. |
| KR101368179B1 (ko) | 2010-11-12 | 2014-03-03 | 포항공과대학교 산학협력단 | 강한 전하를 가지는 나노입자 표면 분자체와 이를 이용한 생접합 및 층상 자기조립 방법 |
| DK2640423T3 (en) | 2010-11-18 | 2017-10-02 | Ischemix Llc | LIPOYL COMPOUNDS AND THEIR USE IN TREATMENT OF ISchemic DAMAGE |
| ITFI20120170A1 (it) * | 2012-08-28 | 2014-03-01 | Consorzio Interuniversitario Nazion Ale Per La Sci | Nuovi composti ad azione anti-allodinica ed anti-iperalgesica. |
| EP3110800A1 (de) | 2014-02-27 | 2017-01-04 | Consorzio Interuniversitario Nazionale Per La Scienza E La Tecnologia Dei Materiali (INSTM) | Neuartige verbindungen mit anti-allodynischer und antihyperalgesicher aktivität |
| CA2941518A1 (en) | 2014-03-03 | 2015-09-11 | Encore Vision, Inc. | Lipoic acid choline ester compositions and methods of use |
| WO2016170990A1 (ja) * | 2015-04-18 | 2016-10-27 | ジェイオーコスメティックス株式会社 | チロシナーゼ活性阻害剤および皮膚外用剤 |
| JP6752551B2 (ja) * | 2015-04-18 | 2020-09-09 | ジェイオーコスメティックス株式会社 | チロシナーゼ活性阻害剤および皮膚外用剤 |
| AU2018258158A1 (en) | 2017-04-25 | 2019-11-21 | Ischemix Llc | Compositions and methods for treating traumatic brain injury |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB935962A (en) | 1960-06-17 | 1963-09-04 | Fujisawa Pharmaceutical Co | Improvements in or relating to the production of 6.8-dithiooctanamides |
| JPS6011494A (ja) | 1983-06-29 | 1985-01-21 | Sumitomo Chem Co Ltd | 有機ゲルマニウム化合物 |
| JPS638316A (ja) | 1986-06-28 | 1988-01-14 | Sansho Seiyaku Kk | 外用剤 |
| FR2710340B1 (fr) | 1993-09-22 | 1995-12-15 | D Hinterland Lucien Dussourd | Dérivés peptidiques de l'alpha-MSH et leur application . |
| US6365623B1 (en) | 1997-11-17 | 2002-04-02 | Nicholas V. Perricone | Treatment of acne using lipoic acid |
| FR2781157B1 (fr) * | 1998-07-15 | 2000-08-25 | Oreal | Composition anti-inflammatoire |
| JP2000169371A (ja) | 1998-10-02 | 2000-06-20 | Sankyo Co Ltd | ジチオラン誘導体を含有する医薬 |
| WO2000020385A1 (en) | 1998-10-02 | 2000-04-13 | Sankyo Company, Limited | Dithiol derivatives |
| ATE277034T1 (de) | 1998-10-26 | 2004-10-15 | Univ New York State Res Found | Liponsaürederivate und deren verwendung bei der behandlung von krankheiten |
| EP1133317A1 (de) | 1998-11-26 | 2001-09-19 | Pentapharm AG | Transportsystemkonjugate |
| US6288106B1 (en) * | 1999-05-25 | 2001-09-11 | Chronorx, Llc | Processes for the synthesis and use of various α-lipoic acid complexes |
| EP1371640B1 (de) * | 2001-03-19 | 2009-10-28 | Senju Pharmaceutical Co., Ltd. | Neues a-liponsäurederivat und dessen verwendung |
-
2002
- 2002-03-18 EP EP02705321A patent/EP1371640B1/de not_active Expired - Lifetime
- 2002-03-18 WO PCT/JP2002/002577 patent/WO2002076935A1/ja not_active Ceased
- 2002-03-18 US US10/472,726 patent/US7700080B2/en not_active Expired - Lifetime
- 2002-03-18 ES ES02705321T patent/ES2331832T3/es not_active Expired - Lifetime
- 2002-03-18 AT AT02705321T patent/ATE446949T1/de not_active IP Right Cessation
- 2002-03-18 JP JP2002576197A patent/JP4072062B2/ja not_active Expired - Lifetime
- 2002-03-18 DE DE60234164T patent/DE60234164D1/de not_active Expired - Lifetime
-
2010
- 2010-03-01 US US12/715,131 patent/US20100152288A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1371640A4 (de) | 2007-10-10 |
| DE60234164D1 (de) | 2009-12-10 |
| US20100152288A1 (en) | 2010-06-17 |
| US20040092586A1 (en) | 2004-05-13 |
| WO2002076935A8 (en) | 2002-10-31 |
| JP4072062B2 (ja) | 2008-04-02 |
| JPWO2002076935A1 (ja) | 2004-07-15 |
| WO2002076935A1 (en) | 2002-10-03 |
| EP1371640A1 (de) | 2003-12-17 |
| ES2331832T3 (es) | 2010-01-18 |
| US7700080B2 (en) | 2010-04-20 |
| EP1371640B1 (de) | 2009-10-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE446949T1 (de) | Neues a-liponsäurederivat und dessen verwendung | |
| EP1586315A4 (de) | Zusammensetzung zur hautaufhellung | |
| DK1613304T3 (da) | DPP-IV-inhibitorer | |
| DE60330757D1 (de) | Verwendung von pyridylamiden als angiogenesehemmer | |
| DK1767535T3 (da) | Syntese af epothiloner, mellemprodukter deraf, analoge og deres anvendelse | |
| DE60105419D1 (de) | Serinprotease-inhibitoren | |
| ATE291024T1 (de) | Neue 4-aminofuropyrimidine und ihre verwendung | |
| ATE450498T1 (de) | Cycloalken-dicarbonsäure-verbindungen als entzündungshemmende, immunmodulatorische und antiproliferative mittel | |
| PE20030061A1 (es) | 1-biaril-1,8-naftiridin-4-ona como inhibidores de fosfodiesterasa-4 | |
| DE60218213D1 (de) | Pyridyloxyalkancarbonsäureamid-derivate verwendbar als fungizide | |
| DE602004031410D1 (de) | Inden derivate als pharmazeutika | |
| DE60204611D1 (de) | Sulfonyl-pyridazinon-derivate zur verwendung als aldose-reduktase-inhibitoren | |
| ATE530552T1 (de) | Pyrrolobenzimidazolone und deren verwendung als antiproliferative mittel | |
| ATE279398T1 (de) | Diazocindionderivate und ihre verwendung als tryptase inhibitoren | |
| ATE471312T1 (de) | Diaryltriazolmethylamin-derivate sowie ihre herstellung und therapeutische verwendung | |
| MXPA03012073A (es) | Amidoderivados heterociclicos. | |
| ATE334977T1 (de) | Discodermolid-analoga und ihre pharmazeutische verwendung | |
| DE60321724D1 (de) | 1,2-diaza-dibenzoazulene als inhibitoren der produfür deren herstellung | |
| DE602004002464D1 (de) | IMIDAZOi4,5-BöCHINOLINDERIVATE UND IHRE VERWENDUNG ALS INHIBITOREN DER INDUZIERBAREN NO-SYNTHASE | |
| ATE448198T1 (de) | Neue alpha-ketoamidderivate und deren verwendung | |
| WO2004099129A3 (en) | Intermediates useful in the synthesis of hiv-protease inhibitors and methods for preparing the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |