ATE447417T1 - Konjugate von angiotensin-peptid analoga und chelatbildner für diagnose und therapie - Google Patents
Konjugate von angiotensin-peptid analoga und chelatbildner für diagnose und therapieInfo
- Publication number
- ATE447417T1 ATE447417T1 AT05722089T AT05722089T ATE447417T1 AT E447417 T1 ATE447417 T1 AT E447417T1 AT 05722089 T AT05722089 T AT 05722089T AT 05722089 T AT05722089 T AT 05722089T AT E447417 T1 ATE447417 T1 AT E447417T1
- Authority
- AT
- Austria
- Prior art keywords
- denotes
- analogas
- angiotensin
- conjugates
- peptide
- Prior art date
Links
- 239000002738 chelating agent Substances 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 150000001413 amino acids Chemical group 0.000 abstract 3
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000002059 diagnostic imaging Methods 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/6425—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20040953 | 2004-03-04 | ||
| PCT/NO2005/000078 WO2005084715A2 (en) | 2004-03-04 | 2005-03-03 | Conjugates of angiotensin peptidic analogues and chelating agents for diagnosis and therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE447417T1 true ATE447417T1 (de) | 2009-11-15 |
Family
ID=34918859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05722089T ATE447417T1 (de) | 2004-03-04 | 2005-03-03 | Konjugate von angiotensin-peptid analoga und chelatbildner für diagnose und therapie |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7763234B2 (de) |
| EP (1) | EP1729823B1 (de) |
| JP (1) | JP2007526300A (de) |
| CN (1) | CN1925876A (de) |
| AT (1) | ATE447417T1 (de) |
| DE (1) | DE602005017475D1 (de) |
| WO (1) | WO2005084715A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0416062D0 (en) * | 2004-07-19 | 2004-08-18 | Amersham Plc | Improved N4 chelator conjugates |
| EP1796733A2 (de) * | 2004-09-29 | 2007-06-20 | GE Healthcare AS | Auf upar gezielte kontrastmittel |
| DE602005025911D1 (de) * | 2004-11-22 | 2011-02-24 | Ge Healthcare As | Kontrastmittel für eine extrazelluläre matrix |
| WO2010089757A2 (en) * | 2008-11-07 | 2010-08-12 | Usv Limited | An improved process for synthesis of cyclic octapeptide |
| US9730916B2 (en) * | 2014-02-27 | 2017-08-15 | Chang Gung Memorial Hospital, Keelung | Nutritional composition and method for improving heart failure |
| EP3759121A1 (de) | 2018-03-01 | 2021-01-06 | Trigemina, Inc. | Markiertes oxytocin und verfahren zur herstellung und verwendung |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3966896A (en) * | 1974-09-06 | 1976-06-29 | Mallinckrodt, Inc. | Radioimmunoassay for plasma renin activity |
| US4647447A (en) | 1981-07-24 | 1987-03-03 | Schering Aktiengesellschaft | Diagnostic media |
| US4687659A (en) | 1984-11-13 | 1987-08-18 | Salutar, Inc. | Diamide-DTPA-paramagnetic contrast agents for MR imaging |
| CA2127284C (en) | 1992-01-03 | 2002-02-05 | Buck A. Rhodes | Protein- and peptide-metal ion pharmaceutical applications |
| ATE314097T1 (de) * | 1996-10-28 | 2006-01-15 | Amersham Health As | Kontrastmittel |
| DE69735901T2 (de) | 1996-10-28 | 2007-05-10 | Ge Healthcare As | Verbesseringen an oder in verbindung mit diagnostischen/therapeutischen mitteln |
| US6230777B1 (en) | 1999-02-04 | 2001-05-15 | Midmac Systems, Inc. | Filter forming and joining apparatus |
| CA2405469C (en) | 2000-04-12 | 2012-03-20 | Amersham Health As | Integrin binding peptide derivatives |
| AU2001288847A1 (en) | 2000-09-07 | 2002-03-22 | Biosyntema Inc. | Conformationally constrained labeled peptides for imaging and therapy |
| BRPI0210886B8 (pt) | 2001-07-10 | 2021-05-25 | Amersham Health As | composto, composição farmacêutica, uso de um composto, e, métodos de geração de imagens, de monitoração do efeito do tratamento de um corpo humano ou animal com uma droga para combater uma condição associada com câncer e de tratamento de câncer ou de uma doença relacionada em um corpo humano ou animal |
| GB0116815D0 (en) * | 2001-07-10 | 2001-08-29 | Nycomed Amersham Plc | Improved chelator conjugates |
| GB0206750D0 (en) | 2002-03-22 | 2002-05-01 | Amersham Plc | Radiofluorination methods |
| NO20030115D0 (no) * | 2003-01-09 | 2003-01-09 | Amersham Health As | Kontrastmiddel |
| WO2005044313A2 (en) | 2003-11-06 | 2005-05-19 | Amersham Health As | Conjugates of angiotensin ii and an imaging moiety |
-
2005
- 2005-03-03 AT AT05722089T patent/ATE447417T1/de not_active IP Right Cessation
- 2005-03-03 DE DE602005017475T patent/DE602005017475D1/de not_active Expired - Lifetime
- 2005-03-03 EP EP05722089A patent/EP1729823B1/de not_active Expired - Lifetime
- 2005-03-03 CN CNA2005800066559A patent/CN1925876A/zh active Pending
- 2005-03-03 WO PCT/NO2005/000078 patent/WO2005084715A2/en not_active Ceased
- 2005-03-03 JP JP2007501740A patent/JP2007526300A/ja active Pending
- 2005-03-03 US US10/591,047 patent/US7763234B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005084715A2 (en) | 2005-09-15 |
| US20070297979A1 (en) | 2007-12-27 |
| EP1729823B1 (de) | 2009-11-04 |
| CN1925876A (zh) | 2007-03-07 |
| EP1729823A2 (de) | 2006-12-13 |
| US7763234B2 (en) | 2010-07-27 |
| DE602005017475D1 (de) | 2009-12-17 |
| JP2007526300A (ja) | 2007-09-13 |
| WO2005084715A3 (en) | 2006-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |