ATE450476T1 - Verfahren und vorrichtung zum einfangen geladener moleküle eines stromes - Google Patents

Verfahren und vorrichtung zum einfangen geladener moleküle eines stromes

Info

Publication number
ATE450476T1
ATE450476T1 AT03781246T AT03781246T ATE450476T1 AT E450476 T1 ATE450476 T1 AT E450476T1 AT 03781246 T AT03781246 T AT 03781246T AT 03781246 T AT03781246 T AT 03781246T AT E450476 T1 ATE450476 T1 AT E450476T1
Authority
AT
Austria
Prior art keywords
flow stream
charged molecules
stream
relates
channel
Prior art date
Application number
AT03781246T
Other languages
English (en)
Inventor
Juan Astorga-Wells
Sang-Ryoul Park
Harold Swerdlow
Gerald Jesson
Ulf Lindberg
Tomas Bergman
Hans Joernvall
Mats Joensson
Original Assignee
Capture Device
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Capture Device filed Critical Capture Device
Application granted granted Critical
Publication of ATE450476T1 publication Critical patent/ATE450476T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/405Concentrating samples by adsorption or absorption
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44756Apparatus specially adapted therefor
    • G01N27/44769Continuous electrophoresis, i.e. the sample being continuously introduced, e.g. free flow electrophoresis [FFE]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0681Filter
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0421Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electrophoretic flow
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/4005Concentrating samples by transferring a selected component through a membrane
    • G01N2001/4011Concentrating samples by transferring a selected component through a membrane being a ion-exchange membrane
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/4005Concentrating samples by transferring a selected component through a membrane
    • G01N2001/4016Concentrating samples by transferring a selected component through a membrane being a selective membrane, e.g. dialysis or osmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Electrochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Automatic Cycles, And Cycles In General (AREA)
  • Preliminary Treatment Of Fibers (AREA)
  • Lining Or Joining Of Plastics Or The Like (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
AT03781246T 2002-12-19 2003-12-19 Verfahren und vorrichtung zum einfangen geladener moleküle eines stromes ATE450476T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0203773A SE0203773D0 (sv) 2002-12-19 2002-12-19 Method and device for capturing charged molecules traveling in a flow stream
PCT/SE2003/002027 WO2004056697A1 (en) 2002-12-19 2003-12-19 Method and device for capturing charged molecules traveling in a flow stream

Publications (1)

Publication Number Publication Date
ATE450476T1 true ATE450476T1 (de) 2009-12-15

Family

ID=20289924

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03781246T ATE450476T1 (de) 2002-12-19 2003-12-19 Verfahren und vorrichtung zum einfangen geladener moleküle eines stromes

Country Status (8)

Country Link
US (1) US7731827B2 (de)
EP (1) EP1572574B8 (de)
JP (1) JP2006510903A (de)
AT (1) ATE450476T1 (de)
AU (1) AU2003288865A1 (de)
DE (1) DE60330385D1 (de)
SE (1) SE0203773D0 (de)
WO (1) WO2004056697A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7066900B2 (en) * 1998-12-23 2006-06-27 Life Therapeutics Removal of metabolic components from blood
JP4492212B2 (ja) * 2004-05-20 2010-06-30 株式会社島津製作所 等電点電気泳動チップ及び装置
JP4424076B2 (ja) * 2004-06-04 2010-03-03 株式会社島津製作所 脱塩用マイクロチップおよび脱塩装置
KR20060058830A (ko) 2004-11-26 2006-06-01 한국표준과학연구원 개별시료 주입구가 없는 다중채널 전기영동장치에 의한분리방법
SE0402966D0 (sv) * 2004-12-06 2004-12-06 Capture Device Ab A device, methods and interfaces for single and multidimensional separations for characterization and/or identification of molecules by mass spectrometry
AU2006208124B2 (en) * 2005-01-25 2011-09-15 Massachusetts Institute Of Technology Electrokinetic concentration device and methods of use thereof
US7872225B2 (en) * 2006-08-25 2011-01-18 Perkinelmer Health Sciences, Inc. Sample component trapping, release, and separation with membrane assemblies interfaced to electrospray mass spectrometry
USRE44887E1 (en) 2005-05-19 2014-05-13 Perkinelmer Health Sciences, Inc. Sample component trapping, release, and separation with membrane assemblies interfaced to electrospray mass spectrometry
US20070023291A1 (en) * 2005-07-15 2007-02-01 Sai Bhavaraju Metal Trap
JP4862115B2 (ja) * 2006-10-04 2012-01-25 国立大学法人北海道大学 マイクロチップおよびマイクロチップ電気泳動装置
US8083821B2 (en) * 2007-04-13 2011-12-27 Giner, Inc. System for modifying the atmosphere within an enclosed space and incubator system including the same
AU2008293381B2 (en) 2007-08-27 2012-07-19 Technion Research & Development Foundation Ltd. pH gradients controlled by electrolysis, and their use in isoelectric focusing
KR20100087130A (ko) * 2007-09-26 2010-08-03 메사추세츠 인스티튜트 오브 테크놀로지 전기역학적 농축 장치 및 그의 사용 방법
US9032441B2 (en) * 2007-12-21 2015-05-12 BrightTALK Limited System and method for self management of a live web event
WO2009120642A1 (en) * 2008-03-26 2009-10-01 Massachusetts Institute Of Technology Methods for fabricating electrokinetic concentration devices
US20090288950A1 (en) * 2008-05-20 2009-11-26 Tihiro Ohkawa Liquid electro-mechanical prime mover
EP2313182A4 (de) * 2008-07-22 2012-11-07 Massachusetts Inst Technology Verstärkte elektokinetische flüssigkeitspumpung, -umschaltung und -entsalzung
EP2467709B1 (de) * 2009-08-18 2018-02-28 Technion Research & Development Foundation Ltd. Protonenkonzentrationstopografien sowie verfahren und vorrichtungen zu ihrer herstellung
CN102472724B (zh) 2009-08-18 2014-08-13 工业研究与发展基金会有限公司 分离分子分析物的方法和装置
US9150610B2 (en) 2009-11-16 2015-10-06 Biomotif Ab Method and apparatus to perform hydrogen-deuterium exchange
US8404491B2 (en) 2010-10-29 2013-03-26 Hewlett-Packard Development Company, L.P. Luminescent chemical sensor integrated with at least one molecular trap
JP5950429B2 (ja) * 2011-05-13 2016-07-13 シャープ株式会社 電気泳動方法、及び電気泳動装置
US20140151229A1 (en) * 2012-12-05 2014-06-05 Caliper Life Sciences, Inc. Manipulation of objects in microfluidic devices using external electrodes
KR20150132125A (ko) * 2013-02-28 2015-11-25 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 거대분자의 통제된 포획, 고정, 및 전달을 위한 통합된 부품을 가진 나노유체 장치 및 관련 분석 방법
FR3024544B1 (fr) * 2014-08-01 2019-06-21 Centre National De La Recherche Scientifique Procede et dispositif de concentration de molecules ou objets dissous en solution.
US10617315B2 (en) 2016-09-30 2020-04-14 Microsoft Technology Licensing, Llc Detecting bipotential with an ionic varistor
US10669572B2 (en) 2017-05-31 2020-06-02 University Of Notre Dame Du Lac Ultra-sensitive multi-target lateral flow molecular assay with field-induced precipitation
DE102017114349A1 (de) * 2017-06-28 2019-01-03 Technische Universität Darmstadt Detektionssystem und Verfahren zu dessen Herstellung
WO2020117712A1 (en) * 2018-12-03 2020-06-11 Neiser Paul Apparatus and method for producing a force
US20220178917A1 (en) * 2019-03-13 2022-06-09 Femtodx, Inc. Biomolecular sensors with desalting module and related methods
DE102022206246A1 (de) * 2022-06-22 2023-12-28 Robert Bosch Gesellschaft mit beschränkter Haftung Mikrofluidiksystem mit Ionenaustauscher-Mischbettharz
CN117339642A (zh) * 2023-08-22 2024-01-05 南京师范大学 一种用于蛋白样品溶液置换或蛋白分离的装置和方法
CN119793199A (zh) * 2025-01-03 2025-04-11 中国原子能科学研究院 一种逆流电泳分离装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4362612A (en) * 1978-04-18 1982-12-07 University Patents, Inc. Isoelectric focusing apparatus
GB8725496D0 (en) * 1987-10-30 1987-12-02 Atomic Energy Authority Uk Electrophoretic separator
EP0962773A1 (de) * 1998-06-03 1999-12-08 Mark Howard Jones Prüfverfahren, Vorrichtung und Markierungsmittel basierend auf Elektrochemie
US6428666B1 (en) * 1999-02-22 2002-08-06 Sandia National Laboratories Electrokinetic concentration of charged molecules
US6942778B1 (en) * 2000-11-28 2005-09-13 Nanogen, Inc. Microstructure apparatus and method for separating differently charged molecules using an applied electric field

Also Published As

Publication number Publication date
EP1572574B1 (de) 2009-12-02
EP1572574B8 (de) 2010-02-17
WO2004056697A1 (en) 2004-07-08
EP1572574A1 (de) 2005-09-14
SE0203773D0 (sv) 2002-12-19
AU2003288865A1 (en) 2004-07-14
DE60330385D1 (de) 2010-01-14
JP2006510903A (ja) 2006-03-30
US7731827B2 (en) 2010-06-08
US20050284762A1 (en) 2005-12-29

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