ATE450476T1 - Verfahren und vorrichtung zum einfangen geladener moleküle eines stromes - Google Patents

Verfahren und vorrichtung zum einfangen geladener moleküle eines stromes

Info

Publication number
ATE450476T1
ATE450476T1 AT03781246T AT03781246T ATE450476T1 AT E450476 T1 ATE450476 T1 AT E450476T1 AT 03781246 T AT03781246 T AT 03781246T AT 03781246 T AT03781246 T AT 03781246T AT E450476 T1 ATE450476 T1 AT E450476T1
Authority
AT
Austria
Prior art keywords
flow stream
charged molecules
stream
relates
channel
Prior art date
Application number
AT03781246T
Other languages
English (en)
Inventor
Juan Astorga-Wells
Sang-Ryoul Park
Harold Swerdlow
Gerald Jesson
Ulf Lindberg
Tomas Bergman
Hans Joernvall
Mats Joensson
Original Assignee
Capture Device
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Capture Device filed Critical Capture Device
Application granted granted Critical
Publication of ATE450476T1 publication Critical patent/ATE450476T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/405—Concentrating samples by adsorption or absorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44769—Continuous electrophoresis, i.e. the sample being continuously introduced, e.g. free flow electrophoresis [FFE]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0421—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electrophoretic flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4005—Concentrating samples by transferring a selected component through a membrane
    • G01N2001/4011—Concentrating samples by transferring a selected component through a membrane being a ion-exchange membrane
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4005—Concentrating samples by transferring a selected component through a membrane
    • G01N2001/4016—Concentrating samples by transferring a selected component through a membrane being a selective membrane, e.g. dialysis or osmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Electrochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Lining Or Joining Of Plastics Or The Like (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Automatic Cycles, And Cycles In General (AREA)
  • Preliminary Treatment Of Fibers (AREA)
AT03781246T 2002-12-19 2003-12-19 Verfahren und vorrichtung zum einfangen geladener moleküle eines stromes ATE450476T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0203773A SE0203773D0 (sv) 2002-12-19 2002-12-19 Method and device for capturing charged molecules traveling in a flow stream
PCT/SE2003/002027 WO2004056697A1 (en) 2002-12-19 2003-12-19 Method and device for capturing charged molecules traveling in a flow stream

Publications (1)

Publication Number Publication Date
ATE450476T1 true ATE450476T1 (de) 2009-12-15

Family

ID=20289924

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03781246T ATE450476T1 (de) 2002-12-19 2003-12-19 Verfahren und vorrichtung zum einfangen geladener moleküle eines stromes

Country Status (8)

Country Link
US (1) US7731827B2 (de)
EP (1) EP1572574B8 (de)
JP (1) JP2006510903A (de)
AT (1) ATE450476T1 (de)
AU (1) AU2003288865A1 (de)
DE (1) DE60330385D1 (de)
SE (1) SE0203773D0 (de)
WO (1) WO2004056697A1 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7066900B2 (en) * 1998-12-23 2006-06-27 Life Therapeutics Removal of metabolic components from blood
JP4492212B2 (ja) * 2004-05-20 2010-06-30 株式会社島津製作所 等電点電気泳動チップ及び装置
JP4424076B2 (ja) * 2004-06-04 2010-03-03 株式会社島津製作所 脱塩用マイクロチップおよび脱塩装置
KR20060058830A (ko) 2004-11-26 2006-06-01 한국표준과학연구원 개별시료 주입구가 없는 다중채널 전기영동장치에 의한분리방법
SE0402966D0 (sv) * 2004-12-06 2004-12-06 Capture Device Ab A device, methods and interfaces for single and multidimensional separations for characterization and/or identification of molecules by mass spectrometry
CA2595840C (en) * 2005-01-25 2013-12-10 Massachusetts Institute Of Technology Electrokinetic concentration device and methods of use thereof
USRE44887E1 (en) 2005-05-19 2014-05-13 Perkinelmer Health Sciences, Inc. Sample component trapping, release, and separation with membrane assemblies interfaced to electrospray mass spectrometry
US7872225B2 (en) * 2006-08-25 2011-01-18 Perkinelmer Health Sciences, Inc. Sample component trapping, release, and separation with membrane assemblies interfaced to electrospray mass spectrometry
US20070023291A1 (en) * 2005-07-15 2007-02-01 Sai Bhavaraju Metal Trap
JP4862115B2 (ja) * 2006-10-04 2012-01-25 国立大学法人北海道大学 マイクロチップおよびマイクロチップ電気泳動装置
US8083821B2 (en) * 2007-04-13 2011-12-27 Giner, Inc. System for modifying the atmosphere within an enclosed space and incubator system including the same
EP2559666B1 (de) * 2007-08-27 2014-07-23 Technion Research & Development Foundation Ltd. Durch Elektrolyse gesteuerte pH-Gradienten und ihre Verwendung bei der isoelektrischen Fokussierung
JP5289452B2 (ja) * 2007-09-26 2013-09-11 マサチューセッツ インスティテュート オブ テクノロジー 動電学的な濃縮装置及びその使用方法
US9032441B2 (en) * 2007-12-21 2015-05-12 BrightTALK Limited System and method for self management of a live web event
US8440063B2 (en) * 2008-03-26 2013-05-14 Massachusetts Institute Of Technology Electrokinetic concentration devices
US20090288950A1 (en) * 2008-05-20 2009-11-26 Tihiro Ohkawa Liquid electro-mechanical prime mover
MX2011000940A (es) * 2008-07-22 2011-03-04 Massachusetts Inst Technology Bombeo, cambio y desalinizacion de fluido, electrocinetico, amplificado.
JP5550729B2 (ja) * 2009-08-18 2014-07-16 テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド プロトン濃度トポグラフィーならびにその生成方法および生成デバイス
WO2011021195A1 (en) 2009-08-18 2011-02-24 Technion Research & Development Foundation Ltd. Methods and devices of separating molecular analytes
US9150610B2 (en) 2009-11-16 2015-10-06 Biomotif Ab Method and apparatus to perform hydrogen-deuterium exchange
US8404491B2 (en) 2010-10-29 2013-03-26 Hewlett-Packard Development Company, L.P. Luminescent chemical sensor integrated with at least one molecular trap
JP5950429B2 (ja) * 2011-05-13 2016-07-13 シャープ株式会社 電気泳動方法、及び電気泳動装置
US20140151229A1 (en) * 2012-12-05 2014-06-05 Caliper Life Sciences, Inc. Manipulation of objects in microfluidic devices using external electrodes
US10261065B2 (en) * 2013-02-28 2019-04-16 The University Of North Carolina At Chapel Hill Nanofluidic devices with integrated components for the controlled capture, trapping, and transport of macromolecules and related methods of analysis
FR3024544B1 (fr) * 2014-08-01 2019-06-21 Centre National De La Recherche Scientifique Procede et dispositif de concentration de molecules ou objets dissous en solution.
US10617315B2 (en) 2016-09-30 2020-04-14 Microsoft Technology Licensing, Llc Detecting bipotential with an ionic varistor
US10669572B2 (en) 2017-05-31 2020-06-02 University Of Notre Dame Du Lac Ultra-sensitive multi-target lateral flow molecular assay with field-induced precipitation
DE102017114349A1 (de) * 2017-06-28 2019-01-03 Technische Universität Darmstadt Detektionssystem und Verfahren zu dessen Herstellung
US20220212202A1 (en) * 2018-12-03 2022-07-07 Paul NEISER Method and apparatus for filtration
US20220178917A1 (en) * 2019-03-13 2022-06-09 Femtodx, Inc. Biomolecular sensors with desalting module and related methods
DE102022206246A1 (de) * 2022-06-22 2023-12-28 Robert Bosch Gesellschaft mit beschränkter Haftung Mikrofluidiksystem mit Ionenaustauscher-Mischbettharz
CN119793199A (zh) * 2025-01-03 2025-04-11 中国原子能科学研究院 一种逆流电泳分离装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4362612A (en) * 1978-04-18 1982-12-07 University Patents, Inc. Isoelectric focusing apparatus
GB8725496D0 (en) * 1987-10-30 1987-12-02 Atomic Energy Authority Uk Electrophoretic separator
EP0962773A1 (de) * 1998-06-03 1999-12-08 Mark Howard Jones Prüfverfahren, Vorrichtung und Markierungsmittel basierend auf Elektrochemie
US6428666B1 (en) * 1999-02-22 2002-08-06 Sandia National Laboratories Electrokinetic concentration of charged molecules
US6942778B1 (en) * 2000-11-28 2005-09-13 Nanogen, Inc. Microstructure apparatus and method for separating differently charged molecules using an applied electric field

Also Published As

Publication number Publication date
SE0203773D0 (sv) 2002-12-19
US7731827B2 (en) 2010-06-08
JP2006510903A (ja) 2006-03-30
EP1572574A1 (de) 2005-09-14
EP1572574B1 (de) 2009-12-02
US20050284762A1 (en) 2005-12-29
EP1572574B8 (de) 2010-02-17
AU2003288865A1 (en) 2004-07-14
DE60330385D1 (de) 2010-01-14
WO2004056697A1 (en) 2004-07-08

Similar Documents

Publication Publication Date Title
DE60330385D1 (de) Verfahren und vorrichtung zum einfangen geladener moleküle eines stromes
DE60025929D1 (de) Anordnung und verfahren zum feststellen und/oder überwachen elektrophysiologischer eigenschaften von ionenkanälen
SG162716A1 (en) Electrodeionization method and device with hydrodynamic flow splitting
MX2009010011A (es) Celda electroquimica y metodo de operacion.
DE69721079D1 (de) Verfahren und vorrichtung zur ionenerzeugung
ATE553377T1 (de) Elektrisch gesteuerte ionentransportvorrichtung
ATE193337T1 (de) Elektrolytisches verfahren zur reinigung von elektrisch leitenden oberflächen
DE50206585D1 (de) Verfahren und vorrichtung zum entionisieren von kühlmedien für brennstoffzellen
MY187664A (en) Apparatus and method for gas capture during electrolysis
DE502004009820D1 (de) Behältnis und Vorrichtung zur Erzeugung von elektrischen Feldern in einzelnen Reaktionsräumen
ATE350514T1 (de) Vorrichtung und verfahren zur elektrolytischen behandlung von elektrisch isolierten strukturen
DE602007006832D1 (de) Simultane säuren- und basenherstellung aus einem wässrigen strom
ZA202005227B (en) Deionization device and method for at least partially deionizing a feed liquid in which an electrolyte is dissolved, and apparatuses using such devices
WO2005114691A3 (en) Charged droplet sprayers
ATE415600T1 (de) Flüssigkeitserhitzungsgerät und verfahren
EP4224592A4 (de) Elektrodenanordnung und verarbeitungsverfahren und -vorrichtung, batteriezelle, batterie und elektrische vorrichtung
ATE440158T1 (de) Verfahren zur elektrochemischen strukturierung eines leiter- oder halbleitermaterials und vorrichtung dafür
WO2005103664A3 (en) Potentiometric electrode with a gradient polymer comprising conductive particles and ionophore molecules
EP4746104A1 (de) Elektrodenanordnung, batteriezelle und elektrische vorrichtung
EP4456304A4 (de) Trennmembranrolle, elektrodenanordnung, batteriezelle, batterie und elektrische vorrichtung
EP4394939A4 (de) Positivelektrodenmaterial, elektrochemische vorrichtung und elektrische vorrichtung
RU2010146628A (ru) Система и способ вызова апоптоза в клетках злокачественных опухолей с целью консервативного лечения
DE69825445D1 (de) Elektrochemische behandlung von ionenaustauschmaterial
WO2009008334A1 (ja) イオン伝導性電解質膜の検査方法及び装置
EP4535465A4 (de) Positivelektrodenmaterial, elektrochemische vorrichtung und elektrische vorrichtung

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties