ATE450865T1 - Zusammensetzungen mit kontrollierter freigabe enthaltend nimesulid - Google Patents

Zusammensetzungen mit kontrollierter freigabe enthaltend nimesulid

Info

Publication number
ATE450865T1
ATE450865T1 AT00992052T AT00992052T ATE450865T1 AT E450865 T1 ATE450865 T1 AT E450865T1 AT 00992052 T AT00992052 T AT 00992052T AT 00992052 T AT00992052 T AT 00992052T AT E450865 T1 ATE450865 T1 AT E450865T1
Authority
AT
Austria
Prior art keywords
controlled release
compositions containing
release compositions
containing nimesulide
nimesulide
Prior art date
Application number
AT00992052T
Other languages
English (en)
Inventor
Amarjit Singh
Rajesh Jain
Original Assignee
Panacea Biotec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panacea Biotec Ltd filed Critical Panacea Biotec Ltd
Application granted granted Critical
Publication of ATE450865T1 publication Critical patent/ATE450865T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT00992052T 1999-09-28 2000-09-27 Zusammensetzungen mit kontrollierter freigabe enthaltend nimesulid ATE450865T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1297DE1999 1999-09-28
PCT/IN2000/000094 WO2001022791A2 (en) 1999-09-28 2000-09-27 Controlled release compositions comprising nimesulide

Publications (1)

Publication Number Publication Date
ATE450865T1 true ATE450865T1 (de) 2009-12-15

Family

ID=11092667

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00992052T ATE450865T1 (de) 1999-09-28 2000-09-27 Zusammensetzungen mit kontrollierter freigabe enthaltend nimesulid

Country Status (26)

Country Link
US (2) US20070128276A1 (de)
EP (1) EP1218889B1 (de)
JP (2) JP4359412B2 (de)
KR (1) KR100621281B1 (de)
CN (2) CN101804041A (de)
AP (1) AP1954A (de)
AT (1) ATE450865T1 (de)
AU (1) AU774099B2 (de)
BG (1) BG66093B1 (de)
BR (1) BR0014383A (de)
CA (1) CA2385890C (de)
CZ (1) CZ20021076A3 (de)
DE (1) DE60043447D1 (de)
DK (1) DK1218889T3 (de)
ES (1) ES2337547T3 (de)
HU (1) HUP0204451A3 (de)
IL (2) IL148864A0 (de)
MX (1) MXPA02003321A (de)
NO (1) NO20021540L (de)
NZ (1) NZ518052A (de)
PT (1) PT1218889E (de)
RS (1) RS50303B (de)
RU (1) RU2238087C2 (de)
UA (1) UA80667C2 (de)
WO (1) WO2001022791A2 (de)
ZA (1) ZA200202411B (de)

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EP1750717B1 (de) * 2004-02-11 2017-07-19 Rubicon Research Private Limited Pharmazeutische zusammensetzungen mit kontrollierter freisetzung und verbesserter bioverfügbarkeit
US20080153779A1 (en) * 2005-02-01 2008-06-26 Jun Liao Gastric Retention and Controlled Release Delivery System
MX2008000967A (es) * 2005-07-20 2008-03-26 Panacea Biotec Ltd Nueva composicion farmaceutica de forma de dosis de liberacion modificada que comprende inhibidor de enzima ciclooxigenasa.
CN100346778C (zh) * 2005-07-22 2007-11-07 海南康力元药业有限公司 尼美舒利缓释组合物
WO2007122637A1 (en) * 2006-04-24 2007-11-01 Panacea Biotec Ltd. Novel low dose pharmaceutical compositions comprising nimesulide, preparation and use thereof
RU2305541C1 (ru) * 2006-07-03 2007-09-10 Федеральное государственное учреждение науки "Московский научно-исследовательский институт эпидемиологии и микробиологии имени Г.Н. Габричевского Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека" (ФГУП МНИИЭМ им. Г.Н. Габричевского Роспотребнадзора) Энтеросолюбильная оболочка
RU2308942C1 (ru) * 2006-07-03 2007-10-27 Александра Вадимовна Мелихова Энтеросолюбильная оболочка и способ покрытия такой оболочкой твердой фармацевтической композиции
AU2008261957A1 (en) 2007-06-08 2008-12-18 Addrenex Pharmaceuticals, Inc. Extended release formulation and method of treating adrenergic dysregulation
RU2363451C2 (ru) * 2007-09-14 2009-08-10 Общество С Ограниченной Ответственностью "Технология Лекарств" Композиция для приготовления обладающей пролонгированным действием лекарственной формы и способ получения этой формы
BE1018280A3 (fr) * 2008-09-09 2010-08-03 Squarepoint Pointcarre Sprl Composition de nimesulide a liberation prolongee.
WO2010038237A2 (en) 2008-09-22 2010-04-08 Rubicon Research Private Limited Compositions exhibiting delayed transit through the gastrointestinal tract
WO2010100657A2 (en) * 2009-03-04 2010-09-10 Fdc Limited A novel oral controlled release dosage forms for water soluble drugs
WO2010138441A1 (en) * 2009-05-28 2010-12-02 Aptapharma, Inc. Multilayer oral tablets containing a non-steroidal anti-inflammatory drug and/or acetaminophen
US8513259B2 (en) 2009-07-03 2013-08-20 Jdp Therapeutics, Inc. Non-sedating antihistamine injection formulations and methods of use thereof
US8263581B2 (en) * 2009-07-03 2012-09-11 Jdp Therapeutics, Inc. Non-sedating antihistamine injection formulations and methods of use thereof
CN102188386B (zh) * 2010-03-02 2013-09-04 海南葫芦娃制药有限公司 尼美舒利缓释微丸及其制备方法
CN102232928A (zh) * 2010-04-20 2011-11-09 广州艾格生物科技有限公司 一种尼美舒利缓释干混悬剂及其制备方法
US20120010216A1 (en) * 2010-07-06 2012-01-12 Brown Arthur M Pharmaceutical compositions containing vanoxerine
CN102485220A (zh) * 2010-12-03 2012-06-06 沈阳药科大学 尼美舒利单层渗透泵控释片
WO2012159077A2 (en) * 2011-05-18 2012-11-22 Board Of Regents, The University Of Texas System Multiple dosing regimen oral drug delivery platform
CN103142565B (zh) * 2012-04-18 2015-04-29 中国人民解放军军事医学科学院毒物药物研究所 一种尼美舒利的缓释药物组合物及其制备方法
PE20161573A1 (es) 2014-02-13 2017-01-19 Incyte Corp Ciclopropilamina como inhibidor de la lsd1
US9493450B2 (en) 2014-02-13 2016-11-15 Incyte Corporation Cyclopropylamines as LSD1 inhibitors
US20150275167A1 (en) * 2014-03-28 2015-10-01 Corning Incorporated Composition and method for cell culture sustained release
WO2016007722A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Triazolopyridines and triazolopyrazines as lsd1 inhibitors
CN105435239B (zh) * 2014-08-29 2019-04-26 武汉光谷人福生物医药有限公司 美索舒利薄膜衣片及其制备方法
PE20180455A1 (es) 2015-04-03 2018-03-05 Incyte Corp Compuestos heterociclicos como inhibidores de lsd1
WO2016189481A1 (en) * 2015-05-25 2016-12-01 Sun Pharmaceutical Industries Limited Once daily oral pharmaceutical composition of isotretinoin
SG10202001219UA (en) 2015-08-12 2020-03-30 Incyte Corp Salts of an lsd1 inhibitor
US9687475B1 (en) 2016-03-24 2017-06-27 Ezra Pharma Llc Extended release pharmaceutical formulations with controlled impurity levels
US9675585B1 (en) 2016-03-24 2017-06-13 Ezra Pharma Extended release pharmaceutical formulations
WO2018190621A1 (ko) * 2017-04-10 2018-10-18 성균관대학교 산학협력단 다공성 위체류층을 포함하는 서방성 제제 및 이의 제조방법
WO2020047198A1 (en) 2018-08-31 2020-03-05 Incyte Corporation Salts of an lsd1 inhibitor and processes for preparing the same
IT202100006776A1 (it) * 2021-03-22 2022-09-22 Univ Degli Studi Genova Metodo di produzione di matrici compatte gastroritentive per il rilascio controllato di sostanze attive e matrici compatte così ottenute
CN117695238A (zh) * 2023-12-19 2024-03-15 新美誉(杭州)生物科技有限公司 一种盐酸曲唑酮缓释片及其制备方法
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Also Published As

Publication number Publication date
EP1218889A2 (de) 2002-07-03
KR100621281B1 (ko) 2006-09-13
EP1218889B1 (de) 2009-12-02
US20080160082A1 (en) 2008-07-03
JP2003534236A (ja) 2003-11-18
HUP0204451A3 (en) 2004-05-28
AU2879901A (en) 2001-04-30
BG106605A (bg) 2002-12-29
MXPA02003321A (es) 2004-09-10
JP4359412B2 (ja) 2009-11-04
RS50303B (sr) 2009-09-08
IL148864A0 (en) 2002-09-12
JP2007217436A (ja) 2007-08-30
UA80667C2 (en) 2007-10-25
CA2385890C (en) 2007-04-03
PT1218889E (pt) 2010-03-08
KR20020097138A (ko) 2002-12-31
NO20021540D0 (no) 2002-03-27
WO2001022791A8 (en) 2002-10-31
DK1218889T3 (da) 2010-04-12
RU2002111365A (ru) 2004-01-27
BR0014383A (pt) 2002-10-22
DE60043447D1 (de) 2010-01-14
CN101804041A (zh) 2010-08-18
US20070128276A1 (en) 2007-06-07
ES2337547T3 (es) 2010-04-27
RU2238087C2 (ru) 2004-10-20
NZ518052A (en) 2005-04-29
HUP0204451A2 (hu) 2003-06-28
WO2001022791A2 (en) 2001-04-05
CA2385890A1 (en) 2001-04-05
PL358369A1 (en) 2004-08-09
AU774099B2 (en) 2004-06-17
NO20021540L (no) 2002-05-28
IL148864A (en) 2008-06-05
CZ20021076A3 (cs) 2002-08-14
AP1954A (en) 2009-02-10
BG66093B1 (bg) 2011-04-29
CN1399543A (zh) 2003-02-26
ZA200202411B (en) 2003-06-26
YU23402A (sh) 2004-12-31
WO2001022791A3 (en) 2002-01-31

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