ATE452209T1 - Verfahren zur in-vitro-diagnose von lungenkarzinomen durch nachweis grösserer alternativer transkripte des klk8-gens zur kodierung von kallicrein 8 und seine verwendung zur prognostizierung von überlebenschancen - Google Patents

Verfahren zur in-vitro-diagnose von lungenkarzinomen durch nachweis grösserer alternativer transkripte des klk8-gens zur kodierung von kallicrein 8 und seine verwendung zur prognostizierung von überlebenschancen

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Publication number
ATE452209T1
ATE452209T1 AT07823868T AT07823868T ATE452209T1 AT E452209 T1 ATE452209 T1 AT E452209T1 AT 07823868 T AT07823868 T AT 07823868T AT 07823868 T AT07823868 T AT 07823868T AT E452209 T1 ATE452209 T1 AT E452209T1
Authority
AT
Austria
Prior art keywords
gene encoding
kallicrein
lung carcinoma
vitro diagnosis
alternative transcripts
Prior art date
Application number
AT07823868T
Other languages
English (en)
Inventor
Mireille Ainciburu
Yves Courty
Colette Jolivet-Reynaud
Chris Planque
Original Assignee
Biomerieux Sa
Univ Francois Rabelais De Tour
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux Sa, Univ Francois Rabelais De Tour filed Critical Biomerieux Sa
Application granted granted Critical
Publication of ATE452209T1 publication Critical patent/ATE452209T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT07823868T 2006-09-28 2007-09-27 Verfahren zur in-vitro-diagnose von lungenkarzinomen durch nachweis grösserer alternativer transkripte des klk8-gens zur kodierung von kallicrein 8 und seine verwendung zur prognostizierung von überlebenschancen ATE452209T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0653983A FR2906537A1 (fr) 2006-09-28 2006-09-28 Procede de diagnostic in vitro du cancer broncho-pulmonaire par detection des transcrits majoritaires alternatifs du gene klk8 codant la kallicreine 8 et son utilisation pour le pronostic de survie
PCT/FR2007/052023 WO2008037930A2 (fr) 2006-09-28 2007-09-27 Procede de diagnostic in vitro du cancer broncho-pulmonaire par detection des transcrits majoritaires alternatifs du gene klk8 codant la kallicreine 8 et son utilisation pour le pronostic de survie

Publications (1)

Publication Number Publication Date
ATE452209T1 true ATE452209T1 (de) 2010-01-15

Family

ID=37762428

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07823868T ATE452209T1 (de) 2006-09-28 2007-09-27 Verfahren zur in-vitro-diagnose von lungenkarzinomen durch nachweis grösserer alternativer transkripte des klk8-gens zur kodierung von kallicrein 8 und seine verwendung zur prognostizierung von überlebenschancen

Country Status (9)

Country Link
US (3) US8236506B2 (de)
EP (1) EP2066807B1 (de)
JP (1) JP5394241B2 (de)
CN (1) CN101522913B (de)
AT (1) ATE452209T1 (de)
DE (1) DE602007003856D1 (de)
ES (1) ES2338490T3 (de)
FR (1) FR2906537A1 (de)
WO (1) WO2008037930A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2906537A1 (fr) 2006-09-28 2008-04-04 Biomerieux Sa Procede de diagnostic in vitro du cancer broncho-pulmonaire par detection des transcrits majoritaires alternatifs du gene klk8 codant la kallicreine 8 et son utilisation pour le pronostic de survie

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FR2749082B1 (fr) 1996-05-24 1998-06-26 Bio Merieux Particules superparamagnetiques et monodispersees
CN1238013A (zh) * 1996-11-14 1999-12-08 梅奥医学教育及研究基金会 转移性前列腺癌的检测方法
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FR2793809B1 (fr) 1999-05-20 2006-07-28 Biomerieux Sa Procede d'analyse de la predisposition genetique d'un patient a au moins une maladie et amplification adaptee a un tel procede
JP2001046065A (ja) * 1999-08-03 2001-02-20 Suntory Ltd 新規セリンプロテアーゼ
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FR2816958B1 (fr) * 2000-11-17 2004-11-26 Biomerieux Sa Procede d'analyse de la predisposition genetique d'un patient au diabete insulino-dependant, dispositif adapte a sa mise en oeuvre et jeu d'amorces d'amplification adapte a un tel procede
FR2906537A1 (fr) * 2006-09-28 2008-04-04 Biomerieux Sa Procede de diagnostic in vitro du cancer broncho-pulmonaire par detection des transcrits majoritaires alternatifs du gene klk8 codant la kallicreine 8 et son utilisation pour le pronostic de survie

Also Published As

Publication number Publication date
JP2010504746A (ja) 2010-02-18
WO2008037930A2 (fr) 2008-04-03
US8236506B2 (en) 2012-08-07
US20130289260A1 (en) 2013-10-31
CN101522913A (zh) 2009-09-02
US20100255466A1 (en) 2010-10-07
EP2066807B1 (de) 2009-12-16
FR2906537A1 (fr) 2008-04-04
US20120295261A1 (en) 2012-11-22
US8716458B2 (en) 2014-05-06
DE602007003856D1 (de) 2010-01-28
EP2066807A2 (de) 2009-06-10
JP5394241B2 (ja) 2014-01-22
ES2338490T3 (es) 2010-05-07
WO2008037930A3 (fr) 2008-06-19
CN101522913B (zh) 2013-12-18
US8486632B2 (en) 2013-07-16

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