ATE452638T1 - Ascomycin enthaltende ophthalmische zubereitungen - Google Patents

Ascomycin enthaltende ophthalmische zubereitungen

Info

Publication number: ATE452638T1
Authority: AT; Austria
Prior art keywords: preparations containing; ophthalmic preparations; ascomycin; containing ascomycin; ophthalmic
Prior art date: 2001-08-23

Application number

AT02767419T

Other languages

English (en)

Inventor

Michelle Wong

Kasey Minick

Saunier Maggy Babiole

Jean-Claude Bizec

Andrea Fetz

Christian Schoch

Original Assignee

Novartis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-08-23

Filing date

2002-08-22

Publication date

2010-01-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23219986&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE452638(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-08-22 Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh

2010-01-15 Application granted granted Critical

2010-01-15 Publication of ATE452638T1 publication Critical patent/ATE452638T1/de

Links

ZDQSOHOQTUFQEM-PKUCKEGBSA-N ascomycin Chemical compound C/C([C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@@H](OC)C[C@@H](C)C\C(C)=C/[C@H](C(C[C@H](O)[C@H]1C)=O)CC)=C\[C@@H]1CC[C@@H](O)[C@H](OC)C1 ZDQSOHOQTUFQEM-PKUCKEGBSA-N 0.000 title 1
ZDQSOHOQTUFQEM-XCXYXIJFSA-N ascomycin Natural products CC[C@H]1C=C(C)C[C@@H](C)C[C@@H](OC)[C@H]2O[C@@](O)([C@@H](C)C[C@H]2OC)C(=O)C(=O)N3CCCC[C@@H]3C(=O)O[C@H]([C@H](C)[C@@H](O)CC1=O)C(=C[C@@H]4CC[C@@H](O)[C@H](C4)OC)C ZDQSOHOQTUFQEM-XCXYXIJFSA-N 0.000 title 1
238000002360 preparation method Methods 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)

AT02767419T 2001-08-23 2002-08-22 Ascomycin enthaltende ophthalmische zubereitungen ATE452638T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US31444801P	2001-08-23	2001-08-23
PCT/EP2002/009408 WO2003017990A2 (en)	2001-08-23	2002-08-22	Ophthalmic composition comprising an ascomycin

Publications (1)

Publication Number	Publication Date
ATE452638T1 true ATE452638T1 (de)	2010-01-15

Family

ID=23219986

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02767419T ATE452638T1 (de)	2001-08-23	2002-08-22	Ascomycin enthaltende ophthalmische zubereitungen

Country Status (27)

Country	Link
US (2)	US20030050255A1 (de)
EP (1)	EP1420787B8 (de)
JP (1)	JP2005501105A (de)
KR (2)	KR20100089108A (de)
CN (1)	CN100366251C (de)
AR (1)	AR035293A1 (de)
AT (1)	ATE452638T1 (de)
AU (1)	AU2002331172B2 (de)
BR (1)	BR0211972A (de)
CA (1)	CA2457034C (de)
CO (1)	CO5560568A2 (de)
DE (1)	DE60234840D1 (de)
EC (1)	ECSP044981A (de)
ES (1)	ES2337130T3 (de)
HU (1)	HUP0402396A3 (de)
IL (1)	IL160374A0 (de)
MX (1)	MXPA04001646A (de)
MY (1)	MY157377A (de)
NO (1)	NO20040775L (de)
NZ (1)	NZ531224A (de)
PE (1)	PE20030311A1 (de)
PL (1)	PL208685B1 (de)
PT (1)	PT1420787E (de)
RU (1)	RU2313344C2 (de)
TW (1)	TWI324925B (de)
WO (1)	WO2003017990A2 (de)
ZA (1)	ZA200400772B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7354574B2 (en)	2002-11-07	2008-04-08	Advanced Ocular Systems Limited	Treatment of ocular disease
BE1015610A3 (nl) *	2003-07-17	2005-06-07	Corrutech Nv	Verbeterde lijm en werkwijze voor het vervaardigen ervan.
US7083802B2 (en) *	2003-07-31	2006-08-01	Advanced Ocular Systems Limited	Treatment of ocular disease
JP2007505932A (ja)	2003-09-18	2007-03-15	マクサイト，インコーポレイテッド	経強膜送達
US7087237B2 (en)	2003-09-19	2006-08-08	Advanced Ocular Systems Limited	Ocular solutions
US7083803B2 (en)	2003-09-19	2006-08-01	Advanced Ocular Systems Limited	Ocular solutions
CA2597590A1 (en)	2005-02-09	2006-08-17	Macusight, Inc.	Formulations for ocular treatment
WO2007011880A2 (en)	2005-07-18	2007-01-25	Minu, L.L.C.	Enhanced ocular neuroprotection/neurostimulation
KR101478164B1 (ko)	2006-02-09	2014-12-31	산텐 세이야꾸 가부시키가이샤	안정한 제제와 그 제조 및 사용 방법
AU2007230964B2 (en)	2006-03-23	2012-07-19	Santen Pharmaceutical Co., Ltd.	Formulations and methods for vascular permeability-related diseases or conditions
WO2009007839A1 (en) *	2007-07-11	2009-01-15	Pfizer Inc.	Pharmaceutical compositions and methods of treating dry eye disorders
WO2009132050A2 (en)	2008-04-21	2009-10-29	Otonomy, Inc.	Auris formulations for treating otic diseases and conditions
US11969501B2 (en)	2008-04-21	2024-04-30	Dompé Farmaceutici S.P.A.	Auris formulations for treating otic diseases and conditions
MY161021A (en)	2008-05-14	2017-03-31	Otonomy Inc	Controlled release corticosteroid and methods for the treatment of otic disorders
US8648119B2 (en)	2008-05-23	2014-02-11	Otonomy, Inc.	Controlled release immunomodulator compositions and methods for the treatment of otic disorders
US8846770B2 (en)	2008-06-18	2014-09-30	Otonomy, Inc.	Controlled release aural pressure modulator compositions and methods for the treatment of OTIC disorders
WO2010011466A2 (en)	2008-06-27	2010-01-28	Otonomy, Inc.	Controlled-release cns modulating compositions and methods for the treatment of otic disorders
US8349353B2 (en)	2008-06-27	2013-01-08	Otonomy, Inc.	Controlled release cytotoxic agent compositions and methods for the treatment of otic disorders
US8496957B2 (en)	2008-07-21	2013-07-30	Otonomy, Inc	Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders
US8399018B2 (en)	2008-07-21	2013-03-19	Otonomy, Inc.	Controlled release ion channel modulator compositions and methods for the treatment of otic disorders
US8318817B2 (en)	2008-07-21	2012-11-27	Otonomy, Inc.	Controlled release antimicrobial compositions and methods for the treatment of otic disorders
WO2010011605A2 (en)	2008-07-21	2010-01-28	Otonomy, Inc.	Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders
CA2751761A1 (en)	2008-10-22	2010-04-29	House Ear Institute	Treatment and/or prevention of inner ear conditions by modulation of a metabotropic glutamate receptor
CN105682742A (zh)	2013-08-27	2016-06-15	奥德纳米有限公司	小儿耳部病症的治疗
AU2016355236C1 (en)	2015-11-16	2022-09-22	Medincell	A method for morselizing and/or targeting pharmaceutically active principles to synovial tissue
EP3512513A4 (de)	2016-09-16	2020-04-15	Otonomy, Inc.	Gelformulierungen für das ohr zur behandlung von otitis externa
JP7699426B2 (ja) *	2018-11-30	2025-06-27	ロート製薬株式会社	光線による障害からの細胞保護用眼科組成物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE132366T1 (de) *	1990-05-29	1996-01-15	Boston Ocular Res	Zusammensetzung zur behandlung von dry eye erkrankungen
US5247076A (en) *	1991-09-09	1993-09-21	Merck & Co., Inc.	Imidazolidyl macrolides having immunosuppressive activity
EP0551626A1 (de) *	1991-12-19	1993-07-21	LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d.	Thermoreversible Gel als pharmazeutische Grundmasse für eine galenische Form
US5302584A (en) *	1992-10-13	1994-04-12	American Home Products Corporation	Carbamates of rapamycin
JPH06345646A (ja) *	1993-06-08	1994-12-20	Fujisawa Pharmaceut Co Ltd	ローション剤
DK0786986T3 (da) *	1994-10-26	2002-04-29	Novartis Ag	Anvendelse af en umættet fedtalkohol
AR004480A1 (es) *	1995-04-06	1998-12-16	Amico Derin C D	Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen
JP4221762B2 (ja) *	1997-04-11	2009-02-12	アステラス製薬株式会社	医薬組成物
CZ287497B6 (cs) *	1997-12-30	2000-12-13	Galena, A. S.	Topické oční přípravky s imunosupresivními látkami
CZ20013769A3 (cs) *	1999-04-30	2002-03-13	Sucampo Ag	Činidlo pro léčbu suchého oka

2002
- 2002-08-21 TW TW091118911A patent/TWI324925B/zh not_active IP Right Cessation
- 2002-08-21 AR ARP020103137A patent/AR035293A1/es unknown
- 2002-08-22 NZ NZ531224A patent/NZ531224A/en not_active IP Right Cessation
- 2002-08-22 MX MXPA04001646A patent/MXPA04001646A/es active IP Right Grant
- 2002-08-22 BR BR0211972-2A patent/BR0211972A/pt active Search and Examination
- 2002-08-22 RU RU2004108463/15A patent/RU2313344C2/ru not_active IP Right Cessation
- 2002-08-22 JP JP2003522510A patent/JP2005501105A/ja active Pending
- 2002-08-22 IL IL16037402A patent/IL160374A0/xx unknown
- 2002-08-22 PL PL367459A patent/PL208685B1/pl not_active IP Right Cessation
- 2002-08-22 DE DE60234840T patent/DE60234840D1/de not_active Expired - Lifetime
- 2002-08-22 AU AU2002331172A patent/AU2002331172B2/en not_active Ceased
- 2002-08-22 KR KR1020107014068A patent/KR20100089108A/ko not_active Abandoned
- 2002-08-22 ES ES02767419T patent/ES2337130T3/es not_active Expired - Lifetime
- 2002-08-22 CA CA2457034A patent/CA2457034C/en not_active Expired - Fee Related
- 2002-08-22 PE PE2002000808A patent/PE20030311A1/es not_active Application Discontinuation
- 2002-08-22 EP EP02767419A patent/EP1420787B8/de not_active Expired - Lifetime
- 2002-08-22 PT PT02767419T patent/PT1420787E/pt unknown
- 2002-08-22 MY MYPI20023102A patent/MY157377A/en unknown
- 2002-08-22 WO PCT/EP2002/009408 patent/WO2003017990A2/en not_active Ceased
- 2002-08-22 AT AT02767419T patent/ATE452638T1/de active
- 2002-08-22 HU HU0402396A patent/HUP0402396A3/hu unknown
- 2002-08-22 KR KR10-2004-7002458A patent/KR20040030157A/ko not_active Ceased
- 2002-08-22 CN CNB028164466A patent/CN100366251C/zh not_active Expired - Fee Related
- 2002-08-23 US US10/227,086 patent/US20030050255A1/en not_active Abandoned
2004
- 2004-01-30 ZA ZA200400772A patent/ZA200400772B/en unknown
- 2004-02-17 NO NO20040775A patent/NO20040775L/no not_active Application Discontinuation
- 2004-02-18 EC EC2004004981A patent/ECSP044981A/es unknown
- 2004-02-18 CO CO04013810A patent/CO5560568A2/es not_active Application Discontinuation
2010
- 2010-11-30 US US12/955,950 patent/US20110071186A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CO5560568A2 (es)	2005-09-30
WO2003017990A3 (en)	2003-08-28
JP2005501105A (ja)	2005-01-13
IL160374A0 (en)	2004-07-25
PE20030311A1 (es)	2003-05-08
WO2003017990A2 (en)	2003-03-06
EP1420787B1 (de)	2009-12-23
KR20040030157A (ko)	2004-04-08
DE60234840D1 (de)	2010-02-04
PT1420787E (pt)	2010-03-01
RU2004108463A (ru)	2005-05-10
AU2002331172B2 (en)	2005-12-01
MXPA04001646A (es)	2004-05-31
HUP0402396A2 (hu)	2005-09-28
RU2313344C2 (ru)	2007-12-27
EP1420787A2 (de)	2004-05-26
PL208685B1 (pl)	2011-05-31
CA2457034A1 (en)	2003-03-06
KR20100089108A (ko)	2010-08-11
HUP0402396A3 (en)	2005-12-28
ES2337130T3 (es)	2010-04-21
HK1065961A1 (en)	2005-03-11
EP1420787B8 (de)	2010-09-01
CA2457034C (en)	2010-07-27
US20110071186A1 (en)	2011-03-24
BR0211972A (pt)	2004-09-21
CN100366251C (zh)	2008-02-06
PL367459A1 (en)	2005-02-21
MY157377A (en)	2016-06-15
NZ531224A (en)	2005-09-30
CN1545414A (zh)	2004-11-10
US20030050255A1 (en)	2003-03-13
TWI324925B (en)	2010-05-21
ZA200400772B (en)	2004-10-11
NO20040775L (no)	2004-02-17
AR035293A1 (es)	2004-05-05
ECSP044981A (es)	2004-04-28

Legal Events

Date

Code

Title

Description

2010-07-15

UEP

Publication of translation of european patent specification

Ref document number: 1420787

Country of ref document: EP

Publication	Publication Date	Title
DE60234840D1 (de)	2010-02-04	Ascomycin enthaltende ophthalmische zubereitungen
DE60208385D1 (de)	2006-02-02	Antineoplasische kombinationspräparate
NO20033556D0 (no)	2003-08-11	Farmasöytiske preparater
NO20034439D0 (no)	2003-10-03	Benzamidinderivater
IS6040A (is)	2001-08-07	Valdekoxib efnablöndur
DE50209261D1 (de)	2007-03-08	Mähvorrichtung
NO20035224D0 (no)	2003-11-24	Oftalmisk pirenzepingel
EP1460900A4 (de)	2004-11-03	Sezernierte humanproteine
NO20014597D0 (no)	2001-09-21	Fremgangsmåte
DK1482936T3 (da)	2007-01-08	Öjenpræparat omfattende ascomycin
DE50209245D1 (de)	2007-02-22	Neuroprotektives medikament
ITMI20010954A0 (it)	2001-05-10	Procedimento di iodurazione
EP1359932A4 (de)	2004-06-30	Tip39 polypeptide
DE50202621D1 (de)	2005-05-04	Zentrifuge
FR2803922B1 (fr)	2002-04-05	Lentille ophtalmique
DK1445641T3 (da)	2008-02-04	Okulære linser
EP1430904A4 (de)	2005-09-14	Desensibilisatoren
DE50009295D1 (de)	2005-02-24	Vernetzerfreie zubereitungen
EP1364654A4 (de)	2007-10-17	Augentropfen
DE50200779D1 (de)	2004-09-16	Planenhalter
DE60206034D1 (de)	2005-10-13	Spritze
FR2824842B1 (fr)	2004-04-30	Phytocystatine
DE50213427D1 (de)	2009-05-20	Durchführungsanordnung
DE60204435D1 (de)	2005-07-07	Spritze
TW540690U (en)	2003-07-01	Lens type compass