ATE132366T1 - Zusammensetzung zur behandlung von dry eye erkrankungen - Google Patents

Zusammensetzung zur behandlung von dry eye erkrankungen

Info

Publication number
ATE132366T1
ATE132366T1 AT91106698T AT91106698T ATE132366T1 AT E132366 T1 ATE132366 T1 AT E132366T1 AT 91106698 T AT91106698 T AT 91106698T AT 91106698 T AT91106698 T AT 91106698T AT E132366 T1 ATE132366 T1 AT E132366T1
Authority
AT
Austria
Prior art keywords
composition
treatment
dry eye
eye diseases
eye
Prior art date
Application number
AT91106698T
Other languages
English (en)
Inventor
Thomas Glonek
Donald R Korb
Jack V Greiner
Original Assignee
Boston Ocular Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Ocular Res filed Critical Boston Ocular Res
Application granted granted Critical
Publication of ATE132366T1 publication Critical patent/ATE132366T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
AT91106698T 1990-05-29 1991-04-25 Zusammensetzung zur behandlung von dry eye erkrankungen ATE132366T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52965790A 1990-05-29 1990-05-29
US63821591A 1991-01-07 1991-01-07

Publications (1)

Publication Number Publication Date
ATE132366T1 true ATE132366T1 (de) 1996-01-15

Family

ID=27063077

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91106698T ATE132366T1 (de) 1990-05-29 1991-04-25 Zusammensetzung zur behandlung von dry eye erkrankungen

Country Status (12)

Country Link
US (1) US5294607A (de)
EP (1) EP0459148B1 (de)
JP (1) JP3281392B2 (de)
AT (1) ATE132366T1 (de)
AU (1) AU648304B2 (de)
CA (1) CA2043366C (de)
DE (1) DE69115990T2 (de)
ES (1) ES2084722T3 (de)
GR (1) GR3019478T3 (de)
IL (1) IL98237A (de)
RU (1) RU2092138C1 (de)
TW (1) TW200396B (de)

Families Citing this family (124)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364632A (en) * 1989-04-05 1994-11-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions
ZA927277B (en) * 1991-10-02 1993-05-19 Boston Ocular Res Dry eye treatment process and solution.
DE69629230D1 (de) * 1995-03-24 2003-09-04 Ocular Res Of Bonton Inc Hydrogellinse mit Lipid-Vorbeschichtigung
DE19511322C2 (de) 1995-03-28 1999-09-02 Mann Gerhard Chem Pharm Fab Sterile Augengele mit einem Gehalt an mittelkettigen Triglyceriden und Verfahren zu deren Herstellung
US5616342A (en) * 1995-04-11 1997-04-01 Pdt, Inc. Emulsioin suitable for administering a poorly water-soluble photosensitizing compound and use thereof
DE19527132A1 (de) * 1995-07-25 1997-01-30 Laevosan Gmbh & Co Kg Ophthalmologische Ozonschutzzusammensetzung
US5696166A (en) * 1995-10-31 1997-12-09 Yanni; John M. Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders
JPH10218760A (ja) * 1997-02-04 1998-08-18 Nobel Igaku Kenkyusho:Kk ドライアイ治療用の微量油添加目薬
ZA989513B (en) 1997-10-21 1999-04-21 Alcon Lab Inc Compositions containing histamine H2 agonists and methods of use in treating dry eye
RU2125427C1 (ru) * 1998-05-27 1999-01-27 Миронова Эмилия Михайловна Средство для лечения глазных заболеваний - оковидит
EP0982025A1 (de) * 1998-08-28 2000-03-01 Wilhelm Prof. Dr. Stoffel Künstliche Tränen
AU2183900A (en) 1998-12-24 2000-07-31 Alcon Laboratories, Inc. Ep4 receptor agonists for treatment of dry eye
US6462080B1 (en) 1998-12-24 2002-10-08 Alcon Manufacturing, Ltd. Prostaglandin E receptor agonists for treatment of dry eye
EP1156809B1 (de) 1999-03-01 2005-12-07 Vista Scientific LLC Ophthalmologische zubereitung die mucin enthält
AUPQ228199A0 (en) * 1999-08-18 1999-09-09 Sly, Anthony William Ophthalmic fluid
PT1228028E (pt) 1999-11-09 2005-10-31 Alcon Inc Sais de hidroxieicosatetraeniato, composicoes e metodos para utilizacao no tratamento de perturbacoes da secura ocular
DE60019322T2 (de) 1999-11-09 2005-09-08 Alcon Inc. Heteroatomunterbrochene analoge von15-hydroxyeicosatetraensäure und verfahren zu deren verwendung
WO2001034550A2 (en) 1999-11-09 2001-05-17 Alcon Universal Ltd. 15-hydroxyeicosatetraenoic acid analogs with enhanced metabolic stability and methods of their use in treating dry eye disorders
HK1045985B (en) 1999-11-09 2004-04-23 Alcon, Inc. 15-hydroxyeicosatetraenoic acid-related compounds and methods of use
WO2001034553A2 (en) 1999-11-09 2001-05-17 Alcon Universal Ltd. 2,2-difluoro 15-hydroxyeicosatetraenoic acid analogs and methods of use
US6803385B2 (en) 1999-11-09 2004-10-12 Alcon, Inc. Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
DK1228027T3 (da) 1999-11-09 2004-07-19 Alcon Inc 3-heteroatomsubstituerede og to carbonhomologe af 15-HETE og fremgangsmåder til anvendelse
US6552084B2 (en) 1999-11-09 2003-04-22 Alcon Universal Ltd. Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
AU1226001A (en) 1999-11-09 2001-06-06 Alcon Universal Limited Phospholipids of hydroxyeicosatetraenoic acid-like derivatives
US6458854B2 (en) 1999-11-09 2002-10-01 Alcon Universal Ltd. Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use
PT1228032E (pt) 1999-11-09 2004-10-29 Alcon Inc Composicoes contendo derivados do acido hidroxieicosatetraenoico e metodos de utilizacao para o tratamento de desordens do olho seco
ATE258791T1 (de) * 1999-11-09 2004-02-15 Alcon Inc Lipoxin-a4 und deren analoge zur behandlung von trockenen augen
CA2386632A1 (en) 1999-11-09 2001-05-17 Alcon, Inc. Omega chain modified 15-hydroxyeicosatetraenoic acid derivatives and methods of their use for the treatment of dry eye
PT1228030E (pt) 1999-11-09 2005-08-31 Alcon Inc Derivados benzenoidicos do acido 15-hidroxieicosatetraenoico e metodos para a sua utilizacao no tratamento das perturbacoes do olho seco
AU2603301A (en) 1999-12-22 2001-07-03 Alcon Universal Limited 6-keto prostaglandin F1alpha and analogs for treating dry eye
US6348508B1 (en) 2000-04-04 2002-02-19 Bausch & Lomb Incorporated Method for treating dry eye
US7524511B1 (en) 2000-07-12 2009-04-28 Rogue Valley Natural Springs, Inc. Method and kit for moisturizing the surface of the eye
PT1304991E (pt) * 2000-07-12 2014-12-09 Rogue Valley Natural Springs Inc Método e kit para a hidratação da superfície do olho
BR0209883A (pt) 2001-05-21 2004-06-08 Alcon Inc Uso de inibidores da proteasoma para o tratamento de distúrbios do olho seco
EP1392322A1 (de) * 2001-05-21 2004-03-03 Alcon, Inc. Methode zur behandlung des trockenen auges
US7112588B2 (en) * 2001-05-21 2006-09-26 Alcon, Inc. Use of proteasome inhibitors to treat dry eye disorders
JP2004527578A (ja) 2001-05-21 2004-09-09 アルコン,インコーポレイテッド ドライアイ障害を処置するためのNF−κBインヒビターの使用
US6872382B1 (en) 2001-05-21 2005-03-29 Alcon, Inc. Use of selective PDE IV inhibitors to treat dry eye disorders
US6645994B1 (en) 2001-06-01 2003-11-11 Alcon, Inc. Method of treating dry eye disorders
FR2827190A1 (fr) * 2001-06-22 2003-01-17 Rhodia Chimie Sa Utilisation d'une huile comprenant un groupement polaire comme aide au depot d'une huile polaire non ionisable
US6750250B1 (en) 2001-07-12 2004-06-15 Alcon, Inc. 11,12-oxidoarachidonic acid derivatives and methods of their use in treating dry eye disorders
DE10141018A1 (de) * 2001-08-22 2003-03-13 Eth Zuerich Eidgenoessische Te Verwendung von negativ geladenen Phospholipiden, sowie Zusammensetzungen umfassend Phospholipide zur Behandlung des Auges
TWI324925B (en) * 2001-08-23 2010-05-21 Novartis Ag Ophthalmic composition
US20040220089A1 (en) * 2001-10-03 2004-11-04 Ellis Edward J. Ophthalmic preparation containing glycoprotein
US20040214754A1 (en) * 2001-10-03 2004-10-28 Ellis Edward J. Ophthalmic preparation containing glycomacropeptide
PL369960A1 (en) * 2001-10-11 2005-05-02 Alcon, Inc. Methods for treating dry eye by a combination of an antiinflammatory steroid and a muc-1 secretagogue
WO2003030894A1 (en) * 2001-10-11 2003-04-17 Alcon, Inc. Methods for treating dry eye
US6656460B2 (en) * 2001-11-01 2003-12-02 Yissum Research Development Method and composition for dry eye treatment
AU782913B2 (en) * 2001-11-02 2005-09-08 Santen Sas Method and composition for dry eye treatment
KR20060013632A (ko) * 2002-05-17 2006-02-13 오쎄라 파마슈티걸즈, 인크. 백내장 및 다른 안질환 발병의 개선
RU2232582C2 (ru) * 2002-07-29 2004-07-20 Уфимский научно-исследовательский институт глазных болезней Глазная пленка
EP1542768A1 (de) * 2002-09-20 2005-06-22 Alcon, Inc. Verwendung von zytokin-synthesehemmern zur behandlung von erkrankungen mit trockenem auge
US20040248794A1 (en) * 2002-12-20 2004-12-09 Yanni John M. Treatment of dry eye by restoring 15-lipoxygenase activity to ocular surface cells
WO2004093878A1 (en) 2003-04-16 2004-11-04 Alcon, Inc. Use of fused pyridazine derivatives for treating dry eye disorders
US7825134B2 (en) * 2003-05-19 2010-11-02 Othera Holding, Inc. Amelioration of cataracts, macular degeneration and other ophthalmic diseases
RU2245137C1 (ru) * 2003-06-18 2005-01-27 Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Фармацевтическая композиция для лечения воспалительных процессов вирусной этиологии в глазном яблоке
KR101188156B1 (ko) * 2003-09-10 2012-10-05 센주 세이야꾸 가부시키가이샤 콘택트렌즈용 안과용 조성물
MXPA03011987A (es) 2003-12-19 2005-06-23 Osio Sancho Alberto Metodo para el tratamiento de la presbicia induciendo cambios en el poder y fisiologia corneal.
US20070082017A1 (en) * 2004-01-10 2007-04-12 Tseng Scheffer C Lipid compositions and methods of use
US20050182039A1 (en) * 2004-02-13 2005-08-18 Bausch & Lomb Incorporated Use of Loteprednol etabonate for the treatment of dry eye
WO2005094836A2 (en) 2004-03-25 2005-10-13 Bausch & Lomb Incorporated Use of loteprednol etabonate for the treatment of dry eye
DE602005017762D1 (de) * 2004-05-14 2009-12-31 Alcon Inc Methode zur behandlung trockener augen und uveitis
US7923471B2 (en) * 2004-05-14 2011-04-12 Alcon, Inc. Method of treating dry eye disorders and uveitis
AU2005262392A1 (en) * 2004-07-01 2006-01-19 Johnson & Johnson Vision Care, Inc. Compositions and methods for treating eye disorders and conditions
JP5272307B2 (ja) * 2004-07-16 2013-08-28 大正製薬株式会社 水性点眼剤
US7223737B1 (en) 2004-08-13 2007-05-29 Alcon, Inc. Method of treating dry eye disorders using glycosides
WO2006022291A1 (ja) 2004-08-27 2006-03-02 Senju Pharmaceutical Co, .Ltd. ドライアイ治療用点眼液
US20060128803A1 (en) * 2004-12-14 2006-06-15 Alcon, Inc. Method of treating dry eye disorders using 13(S)-HODE and its analogs
US9161905B2 (en) * 2005-01-12 2015-10-20 Ocular Research Of Boston, Inc. Dry eye treatment
AU2012201476B2 (en) * 2005-01-12 2014-07-17 Ocular Research Of Boston, Inc Dry eye treatment
TW200722109A (en) * 2005-03-31 2007-06-16 Bausch & Lomb Polysaccharide and polyol composition for treating dry eye and related methods of manufacture and methods of use
TWI393567B (zh) * 2005-03-31 2013-04-21 Bausch & Lomb 治療乾眼之組合物及相關之製造方法及使用方法
ES2619303T3 (es) 2005-06-01 2017-06-26 Edison Pharmaceuticals, Inc. Productos terapéuticos redox activos para el tratamiento de enfermedades mitocondriales y otras afecciones y modulación de biomarcadores energéticos
WO2007005421A2 (en) * 2005-07-01 2007-01-11 Bausch & Lomb Incorporated Long lasting alginate dry eye, related methods of manufacture and methods of use
WO2007058935A2 (en) * 2005-11-14 2007-05-24 Bausch & Lomb Incorporated Ophthalmic composition for dry eye therapy
JP6033177B2 (ja) * 2006-01-13 2016-11-30 大正製薬株式会社 O/w型エマルション水性点眼剤
JP5748385B2 (ja) * 2006-01-13 2015-07-15 大正製薬株式会社 O/w型エマルション水性点眼剤
WO2007100652A2 (en) 2006-02-22 2007-09-07 Edison Pharmaceuticals, Inc. Side chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
US7745461B1 (en) 2006-02-27 2010-06-29 Alcon Research, Ltd. Method of treating dry eye disorders
ES2284398B2 (es) 2006-04-27 2008-12-16 Universidad Complutense De Madrid Formulacion de vesiculas liposomales en soluciones acuosas con caracteristicas de pelicula lagrimal.
US7691811B2 (en) * 2006-05-25 2010-04-06 Bodor Nicholas S Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye
CN101484187B (zh) * 2006-07-07 2012-12-26 博士伦公司 包含解离的糖皮质激素受体激动剂和免疫抑制剂的用于治疗干眼症的组合物
US20080057022A1 (en) * 2006-08-30 2008-03-06 Erning Xia Ophthalmic Pharmaceutical Compositions and Uses Thereof
US8138156B2 (en) * 2006-10-18 2012-03-20 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
US20080095754A1 (en) * 2006-10-18 2008-04-24 Burke Susan E Ophthalmic compositions comprising diglycine
US20080095863A1 (en) * 2006-10-24 2008-04-24 Alcon Manufacturing Ltd. 2-pyrrolidone derivatives for preservation of ophthalmic, otic and nasal compositions
WO2008052037A2 (en) * 2006-10-24 2008-05-02 Alcon Research, Ltd. Packaging materials for formulations containing 2-pyrrolidone derivatives
US20080188573A1 (en) * 2007-02-02 2008-08-07 Alcon Research, Ltd. Use of thy1-fp transgenic mouse for the identification of ophthalmic agents
WO2008120249A1 (en) * 2007-03-30 2008-10-09 Sifi S.P.A. Pharmaceutical formulations based on apolar and polar lipids for ophthalmic use
WO2008137496A1 (en) 2007-05-04 2008-11-13 Bausch & Lomb Incorporated Compositions for reducing, ameliorating, treating, or preventing condition of dry eye and methods of making and using same
CN101754745A (zh) * 2007-05-07 2010-06-23 博士伦公司 用于缓解、改善、治疗或预防干眼症的组合物及其制备和使用方法
WO2008154129A1 (en) * 2007-06-08 2008-12-18 Bausch & Lomb Incorporated Pharmaceutical compositions and method for treating, reducing, ameliorating, alleviating, or preventing dry eye
US20090142292A1 (en) * 2007-12-03 2009-06-04 Blackwell Richard I Method For The Mitigation of Symptoms of Dry Eye
US8629099B2 (en) * 2008-03-25 2014-01-14 Bausch & Lomb Incorporated Ophthalmic compositions comprising a dipeptide
MX363223B (es) 2008-09-10 2019-03-15 Bioelectron Tech Corp Tratamiento de trastornos generalizados del desarrollo con terapeuticos con actividad redox.
CA2736380C (en) * 2008-09-15 2013-05-28 Bausch & Lomb Incorporated Compositions comprising polymers having amino sugar units and methods of making and using same
US8539938B2 (en) * 2009-03-12 2013-09-24 Ford Global Technologies, Llc Fuel systems and methods for controlling fuel systems in a vehicle with multiple fuel tanks
CA2777479C (en) 2009-04-28 2017-10-17 Ptc Therapeutics, Inc. Treatment of leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones
TWI478730B (zh) * 2009-12-03 2015-04-01 Alcon Res Ltd 眼科乳劑
US8658614B2 (en) 2010-08-13 2014-02-25 The University of Texas Health Science Center Aptamer-containing compositions and methods for targeting E-selectin
US9161531B2 (en) 2011-02-23 2015-10-20 Donald R. Korb High alcohol content sanitizer
US8859525B2 (en) 2011-07-19 2014-10-14 Bausch & Lomb Incorporated Pharmaceutical compositions comprising mushroom-based polysaccharides and uses thereof
KR20140069210A (ko) 2011-09-22 2014-06-09 보오슈 앤드 롬 인코포레이팃드 안과적 겔 조성물
US8664180B2 (en) 2012-02-06 2014-03-04 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
US8324171B1 (en) 2012-02-06 2012-12-04 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
US9278132B2 (en) 2012-02-13 2016-03-08 Bausch & Lomb Incorporated Ophthalmic pharmaceutical compositions and methods of making and using same
AU2013222801B2 (en) 2012-02-24 2015-09-17 Bausch & Lomb Incorporated Ophthalmic compositions with alkoxylated natural waxes
JP6016465B2 (ja) * 2012-06-12 2016-10-26 ロート製薬株式会社 ビタミンa類を含有する水性組成物
DK2883104T3 (da) 2012-08-10 2024-07-29 Osio Corp D/B/A Yolia Health Anvendelse af kontaktlinse ved behandling af en ofthalmologisk lidelse
CN105188779B (zh) 2013-01-24 2017-12-12 博士伦公司 天然蜡的聚(氮/胺)衍生物和眼用组合物
WO2015138604A1 (en) 2014-03-12 2015-09-17 University Of Virginia Patent Foundation Compositions and methods for treating eye infections and disease
CA2947741A1 (en) 2014-05-05 2015-11-12 Thetis Pharmaceuticals Llc Compositions and methods relating to ionic salts of peptides
US9999626B2 (en) 2014-06-18 2018-06-19 Thetis Pharmaceuticals Llc Mineral amino-acid complexes of active agents
US12414937B2 (en) 2015-11-05 2025-09-16 University Of Louisville Research Foundation, Inc. Local and regional anesthesia and analgesia
US10703701B2 (en) 2015-12-17 2020-07-07 Ptc Therapeutics, Inc. Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders
ES2827796T3 (es) 2016-06-03 2021-05-24 Thetis Pharmaceuticals Llc Composiciones y procedimientos relativos a sales de mediadores pro-resolutivos especializados de inflamación
US9981041B2 (en) 2016-08-23 2018-05-29 Ira Jason Salzman Ophthalmic lubricating spray
US12233017B2 (en) 2016-10-14 2025-02-25 Olympic Ophthalmics, Inc. Quiet handheld devices and methods for treatment of disorders
US20180296390A1 (en) * 2017-04-18 2018-10-18 David Hoare Apparatus and method for treating a number of eye conditions of a user including dry eye syndrome and/or burns to the eyes
TWI884130B (zh) 2018-02-21 2025-05-21 瑞士商愛爾康公司 基於脂質的眼用乳劑
US11147736B2 (en) 2018-02-26 2021-10-19 Olympic Ophthalmics, Inc. Therapeutic handheld devices for disorders
US11278493B2 (en) 2018-12-10 2022-03-22 EternaTear, Inc. Ophthalmic formulations providing durable ocular lubrication
US11471475B1 (en) 2022-03-08 2022-10-18 Ralph P. Stone Ophthalmic suspension vehicles and related methods for pharmaceutical ingredient delivery
US11679078B1 (en) 2022-03-08 2023-06-20 EternaTear, Inc. Ophthalmic formulations and related methods

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4677099A (en) * 1981-09-04 1987-06-30 Yeda Research And Development Co., Ltd. Medical processes employing a novel lipid fraction
US4421748A (en) * 1982-07-13 1983-12-20 Trager Seymour F Artificial tear aid
JPH02500360A (ja) * 1986-07-28 1990-02-08 リポソーム テクノロジー,インコーポレイテッド 粘膜組織上での高い保持力を有するリポソーム
US4839175A (en) * 1986-07-28 1989-06-13 Liposome Technology, Inc. Liposomes with enhanced retention on mucosal tissue
US4804539A (en) * 1986-07-28 1989-02-14 Liposome Technology, Inc. Ophthalmic liposomes
US4818537A (en) * 1986-10-21 1989-04-04 Liposome Technology, Inc. Liposome composition for treating dry eye
US4914088A (en) * 1987-04-02 1990-04-03 Thomas Glonek Dry eye treatment solution and method
US4866049A (en) * 1987-08-10 1989-09-12 Spectra Pharmaceutical Services, Inc. Ophthalmic compositionn and method of using same
AU614465B2 (en) * 1989-04-05 1991-08-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions

Also Published As

Publication number Publication date
GR3019478T3 (en) 1996-07-31
EP0459148A2 (de) 1991-12-04
TW200396B (de) 1993-02-21
ES2084722T3 (es) 1996-05-16
JPH04279525A (ja) 1992-10-05
AU7619191A (en) 1992-08-06
EP0459148A3 (en) 1992-10-14
IL98237A (en) 1996-08-04
CA2043366C (en) 1999-01-05
CA2043366A1 (en) 1991-11-30
DE69115990D1 (de) 1996-02-15
JP3281392B2 (ja) 2002-05-13
DE69115990T2 (de) 1996-05-30
US5294607A (en) 1994-03-15
AU648304B2 (en) 1994-04-21
EP0459148B1 (de) 1996-01-03
RU2092138C1 (ru) 1997-10-10
IL98237A0 (en) 1992-06-21

Similar Documents

Publication Publication Date Title
DE69115990D1 (de) Zusammensetzung zur Behandlung von Dry Eye Erkrankungen
ATE80290T1 (de) Loesung zur behandlung von ''dry-eye''erkrankungen.
DE4391418T1 (de) Vorrichtung zur elektrochemischen Behandlung von Wasser
ATE190224T1 (de) Tensidefreie wasser-in-öl emulsion
DE69022249D1 (de) Knochenwachsapplikator zur Behandlung von Knochengewebe.
DE69609868D1 (de) Neue steroidester zur behandlung von hauterkrankungen
IT7927466A0 (it) Procedimento per la deidratazione e l'igienizzazione dei fanghi di acque di scarico.
DE69512509D1 (de) Eigenschaften von Gesichtpheromonen von Katzen
DK526489A (da) Bademiddel
DE69126776D1 (de) Parasitizide zusammensetzung und verfahren zu ihrer herstellung und ihre verwendung
DE69404785D1 (de) Vorrichtung zur Behandlung von Oberflächen
BE888082A (fr) Compositions cosmetiques ou pharmaceutiques sous forme d'emulsions stables du type huile-dans-l'eau
DE68914657D1 (de) Vorrichtung zur herstellung von eiskugeln und anwendung derselben zwecks oberflächenbehandlung.
DE69314234D1 (de) Konservierte Polysiloxanemulsion zur Behandlung von Geweben
DE59106539D1 (de) Verfahren zur Oberflächenbehandlung von Bauteilen.
ATE106736T1 (de) Verwendung von dimethylpolysiloxan zur behandlung von erkrankungen des gastrointestinaltraktes.
IT7924778A0 (it) Procedimento per l'innesto di particelle di gomma dienica in emulsione.
EP0844017A4 (de) Prozess zur herstellung eines emulgators und emulgierte zusammensetzung
DE69420487D1 (de) Vorrichtung zur thermischen Behandlung von laufenden Garnen
DE69412178D1 (de) Apparat zur Behandlung von Lagen
DE68903930D1 (de) Lipidemulsion zur behandlung von aids.
ATE204337T1 (de) Verfahren zur behandlung von leder mit tensiden zur verbesserung der hydrophobierwirkung
DE69731981D1 (de) Neue verbesserte formulierung zur behandlung von thromboembolismus
EP0139460A3 (de) Benzodiazepine und ihre therapeutische Verwendung
DE69101124D1 (de) Verfahren zur Herstellung von Mikrokapseln, welche hydrophobe Flüssigkeiten enthalten, Mikrokapseln und Verwendung derselben in Durchschreibpapieren.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee