ATE132366T1 - Zusammensetzung zur behandlung von dry eye erkrankungen - Google Patents

Zusammensetzung zur behandlung von dry eye erkrankungen

Info

Publication number
ATE132366T1
ATE132366T1 AT91106698T AT91106698T ATE132366T1 AT E132366 T1 ATE132366 T1 AT E132366T1 AT 91106698 T AT91106698 T AT 91106698T AT 91106698 T AT91106698 T AT 91106698T AT E132366 T1 ATE132366 T1 AT E132366T1
Authority
AT
Austria
Prior art keywords
composition
treatment
dry eye
eye diseases
eye
Prior art date
Application number
AT91106698T
Other languages
English (en)
Inventor
Thomas Glonek
Donald R Korb
Jack V Greiner
Original Assignee
Boston Ocular Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Ocular Res filed Critical Boston Ocular Res
Application granted granted Critical
Publication of ATE132366T1 publication Critical patent/ATE132366T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)
AT91106698T 1990-05-29 1991-04-25 Zusammensetzung zur behandlung von dry eye erkrankungen ATE132366T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52965790A 1990-05-29 1990-05-29
US63821591A 1991-01-07 1991-01-07

Publications (1)

Publication Number Publication Date
ATE132366T1 true ATE132366T1 (de) 1996-01-15

Family

ID=27063077

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91106698T ATE132366T1 (de) 1990-05-29 1991-04-25 Zusammensetzung zur behandlung von dry eye erkrankungen

Country Status (12)

Country Link
US (1) US5294607A (de)
EP (1) EP0459148B1 (de)
JP (1) JP3281392B2 (de)
AT (1) ATE132366T1 (de)
AU (1) AU648304B2 (de)
CA (1) CA2043366C (de)
DE (1) DE69115990T2 (de)
ES (1) ES2084722T3 (de)
GR (1) GR3019478T3 (de)
IL (1) IL98237A (de)
RU (1) RU2092138C1 (de)
TW (1) TW200396B (de)

Families Citing this family (124)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364632A (en) * 1989-04-05 1994-11-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions
ZA927277B (en) * 1991-10-02 1993-05-19 Boston Ocular Res Dry eye treatment process and solution.
EP0733918B1 (de) * 1995-03-24 2003-07-30 Ocular Research of Boston, Inc. Hydrogellinse mit Lipid-Vorbeschichtigung
DE19511322C2 (de) 1995-03-28 1999-09-02 Mann Gerhard Chem Pharm Fab Sterile Augengele mit einem Gehalt an mittelkettigen Triglyceriden und Verfahren zu deren Herstellung
US5616342A (en) * 1995-04-11 1997-04-01 Pdt, Inc. Emulsioin suitable for administering a poorly water-soluble photosensitizing compound and use thereof
DE19527132A1 (de) * 1995-07-25 1997-01-30 Laevosan Gmbh & Co Kg Ophthalmologische Ozonschutzzusammensetzung
US5696166A (en) * 1995-10-31 1997-12-09 Yanni; John M. Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders
JPH10218760A (ja) * 1997-02-04 1998-08-18 Nobel Igaku Kenkyusho:Kk ドライアイ治療用の微量油添加目薬
ZA989513B (en) 1997-10-21 1999-04-21 Alcon Lab Inc Compositions containing histamine H2 agonists and methods of use in treating dry eye
RU2125427C1 (ru) * 1998-05-27 1999-01-27 Миронова Эмилия Михайловна Средство для лечения глазных заболеваний - оковидит
EP0982025A1 (de) * 1998-08-28 2000-03-01 Wilhelm Prof. Dr. Stoffel Künstliche Tränen
AU2183900A (en) 1998-12-24 2000-07-31 Alcon Laboratories, Inc. Ep4 receptor agonists for treatment of dry eye
AU2183800A (en) 1998-12-24 2000-07-31 Alcon Laboratories, Inc. Prostaglandin e agonists for treatment of dry eye
JP2002538124A (ja) 1999-03-01 2002-11-12 ヴィスタ サイエンティフィック エルエルシー ムチンを含む眼科用調合物
AUPQ228199A0 (en) * 1999-08-18 1999-09-09 Sly, Anthony William Ophthalmic fluid
PT1228030E (pt) 1999-11-09 2005-08-31 Alcon Inc Derivados benzenoidicos do acido 15-hidroxieicosatetraenoico e metodos para a sua utilizacao no tratamento das perturbacoes do olho seco
DE60019322T2 (de) 1999-11-09 2005-09-08 Alcon Inc. Heteroatomunterbrochene analoge von15-hydroxyeicosatetraensäure und verfahren zu deren verwendung
US6255343B1 (en) 1999-11-09 2001-07-03 Alcon Universal Ltd. 2,2-difluoro 15-hydroxyeicosatetraenoic acid analogs and methods of use
ATE258791T1 (de) * 1999-11-09 2004-02-15 Alcon Inc Lipoxin-a4 und deren analoge zur behandlung von trockenen augen
US6331644B1 (en) 1999-11-09 2001-12-18 Alcon Universal Ltd. 3-heteroatom substituted and two carbon homologs of 15-HETE and methods of use
WO2001034550A2 (en) 1999-11-09 2001-05-17 Alcon Universal Ltd. 15-hydroxyeicosatetraenoic acid analogs with enhanced metabolic stability and methods of their use in treating dry eye disorders
BR0015402A (pt) 1999-11-09 2002-06-25 Alcon Inc Derivados de ácido 15-hidroxieicosatetraenóico de cadeia Èmega modificada e métodos de seu uso para o tratamento de olho seco
DK1228032T3 (da) 1999-11-09 2004-11-01 Alcon Inc Præparater, som indeholder hydroxyicosatetraensyrederivater, og fremgangsmåder til anvendelse ved behandling af öjentörhedslidelser
US6803385B2 (en) 1999-11-09 2004-10-12 Alcon, Inc. Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
DE60007547T2 (de) 1999-11-09 2004-06-17 Alcon, Inc. 15-hydroxyeicosatetraensäure verwandte verbindungen und anwendungsverfahren
KR20020050240A (ko) 1999-11-09 2002-06-26 구이도 콜러, 스테판 바슬러 하이드록시에이코사테트라에노에이트 염, 조성물 및 안구건조증 치료에서의 사용 방법
AU1226001A (en) 1999-11-09 2001-06-06 Alcon Universal Limited Phospholipids of hydroxyeicosatetraenoic acid-like derivatives
US6458854B2 (en) 1999-11-09 2002-10-01 Alcon Universal Ltd. Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use
US6552084B2 (en) 1999-11-09 2003-04-22 Alcon Universal Ltd. Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
US6576663B2 (en) 1999-12-22 2003-06-10 Alcon, Inc. 6-Keto prostaglandin F1α and analogs for treating dry eye
US6348508B1 (en) 2000-04-04 2002-02-19 Bausch & Lomb Incorporated Method for treating dry eye
US7524511B1 (en) 2000-07-12 2009-04-28 Rogue Valley Natural Springs, Inc. Method and kit for moisturizing the surface of the eye
AU2001273251B2 (en) * 2000-07-12 2005-03-24 Rogue Valley Natural Springs, Inc. Method and kit for moisturizing the surface of the eye
US20030008853A1 (en) * 2001-05-21 2003-01-09 Alcon, Inc. Method for treating dry eye disorders
BR0209965A (pt) 2001-05-21 2004-04-06 Alcon Inc Uso de inibidores de nf-kappab para tratar distúrbios do olho seco
ATE353667T1 (de) 2001-05-21 2007-03-15 Alcon Inc Verwendung von proteasom-inhibitoren zur behandlung des trockenen auges
US6872382B1 (en) 2001-05-21 2005-03-29 Alcon, Inc. Use of selective PDE IV inhibitors to treat dry eye disorders
US7112588B2 (en) * 2001-05-21 2006-09-26 Alcon, Inc. Use of proteasome inhibitors to treat dry eye disorders
US6645994B1 (en) 2001-06-01 2003-11-11 Alcon, Inc. Method of treating dry eye disorders
FR2827190A1 (fr) * 2001-06-22 2003-01-17 Rhodia Chimie Sa Utilisation d'une huile comprenant un groupement polaire comme aide au depot d'une huile polaire non ionisable
US6750250B1 (en) 2001-07-12 2004-06-15 Alcon, Inc. 11,12-oxidoarachidonic acid derivatives and methods of their use in treating dry eye disorders
DE10141018A1 (de) * 2001-08-22 2003-03-13 Eth Zuerich Eidgenoessische Te Verwendung von negativ geladenen Phospholipiden, sowie Zusammensetzungen umfassend Phospholipide zur Behandlung des Auges
AR035293A1 (es) * 2001-08-23 2004-05-05 Novartis Ag Composicion oftalmica.
US20040214754A1 (en) * 2001-10-03 2004-10-28 Ellis Edward J. Ophthalmic preparation containing glycomacropeptide
US20040220089A1 (en) * 2001-10-03 2004-11-04 Ellis Edward J. Ophthalmic preparation containing glycoprotein
US20030109508A1 (en) * 2001-10-11 2003-06-12 Alcon, Inc. Methods for treating dry eye
MXPA04003299A (es) * 2001-10-11 2004-07-23 Alcon Inc Metodos para tratar la resequedad ocular mediante una combinacion de un esteroide antiinflamatorio y un secretagogo muc-1.
US6656460B2 (en) * 2001-11-01 2003-12-02 Yissum Research Development Method and composition for dry eye treatment
AU782913B2 (en) * 2001-11-02 2005-09-08 Santen Sas Method and composition for dry eye treatment
CN100469776C (zh) * 2002-05-17 2009-03-18 奥特拉控股公司 白内障和其它眼病发展的改善
RU2232582C2 (ru) * 2002-07-29 2004-07-20 Уфимский научно-исследовательский институт глазных болезней Глазная пленка
BR0314603A (pt) * 2002-09-20 2005-07-26 Alcon Inc Uso de inibidores da sìntese de citoquina para o tratamento de distúrbios de olhos secos
AU2003303623A1 (en) * 2002-12-20 2004-07-29 Alcon, Inc. Treatment of dry eye by restoring 15-lipoxygenase activity to ocular surface cells
US7235556B2 (en) 2003-04-16 2007-06-26 Alcon, Inc. Methods of treating dry eye disorders
US7825134B2 (en) * 2003-05-19 2010-11-02 Othera Holding, Inc. Amelioration of cataracts, macular degeneration and other ophthalmic diseases
RU2245137C1 (ru) * 2003-06-18 2005-01-27 Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Фармацевтическая композиция для лечения воспалительных процессов вирусной этиологии в глазном яблоке
US20070053861A1 (en) * 2003-09-10 2007-03-08 Senju Pharmaceutical Co., Ltd. Ophthalmic composition for contact lens
MXPA03011987A (es) 2003-12-19 2005-06-23 Osio Sancho Alberto Metodo para el tratamiento de la presbicia induciendo cambios en el poder y fisiologia corneal.
WO2005067892A1 (en) * 2004-01-10 2005-07-28 Biolipid, Inc. Lipid compositions and methods of use
US20050182039A1 (en) * 2004-02-13 2005-08-18 Bausch & Lomb Incorporated Use of Loteprednol etabonate for the treatment of dry eye
MXPA06010849A (es) 2004-03-25 2007-03-08 Bausch & Lomb Uso de loteprednol etabonato para el tratamiento del ojo seco.
CN100522147C (zh) * 2004-05-14 2009-08-05 爱尔康公司 5,6,7-三羟基庚酸及其类似物在制备治疗干眼病和眼色素层炎药物中的应用
US7923471B2 (en) * 2004-05-14 2011-04-12 Alcon, Inc. Method of treating dry eye disorders and uveitis
CN101043884A (zh) * 2004-07-01 2007-09-26 谢彭斯眼科研究公司 用于治疗眼部疾病和病症的组合物和方法
JP5272307B2 (ja) * 2004-07-16 2013-08-28 大正製薬株式会社 水性点眼剤
US7223737B1 (en) 2004-08-13 2007-05-29 Alcon, Inc. Method of treating dry eye disorders using glycosides
CN101005834A (zh) 2004-08-27 2007-07-25 千寿制药株式会社 干眼症治疗用滴眼液
US20060128803A1 (en) * 2004-12-14 2006-06-15 Alcon, Inc. Method of treating dry eye disorders using 13(S)-HODE and its analogs
AU2012201476B2 (en) * 2005-01-12 2014-07-17 Ocular Research Of Boston, Inc Dry eye treatment
US9161905B2 (en) * 2005-01-12 2015-10-20 Ocular Research Of Boston, Inc. Dry eye treatment
TW200722109A (en) * 2005-03-31 2007-06-16 Bausch & Lomb Polysaccharide and polyol composition for treating dry eye and related methods of manufacture and methods of use
TWI393567B (zh) * 2005-03-31 2013-04-21 Bausch & Lomb 治療乾眼之組合物及相關之製造方法及使用方法
CA2610152C (en) 2005-06-01 2018-04-10 Edison Pharmaceuticals, Inc. Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
US20070004672A1 (en) * 2005-07-01 2007-01-04 Dharmendra Jani Long lasting alginate dry eye, related methods of manufacture and methods of use
WO2007058935A2 (en) * 2005-11-14 2007-05-24 Bausch & Lomb Incorporated Ophthalmic composition for dry eye therapy
JP6033177B2 (ja) * 2006-01-13 2016-11-30 大正製薬株式会社 Ｏ／ｗ型エマルション水性点眼剤
JP5748385B2 (ja) * 2006-01-13 2015-07-15 大正製薬株式会社 Ｏ／ｗ型エマルション水性点眼剤
EA019675B1 (ru) 2006-02-22 2014-05-30 Эдисон Фармасьютикалз, Инк. Редокс-активные терапевтические средства для лечения митохондриальных заболеваний и модуляции биомаркера коэнзима q
US7745461B1 (en) 2006-02-27 2010-06-29 Alcon Research, Ltd. Method of treating dry eye disorders
ES2284398B2 (es) 2006-04-27 2008-12-16 Universidad Complutense De Madrid Formulacion de vesiculas liposomales en soluciones acuosas con caracteristicas de pelicula lagrimal.
US7691811B2 (en) * 2006-05-25 2010-04-06 Bodor Nicholas S Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye
BRPI0714155A2 (pt) * 2006-07-07 2012-12-25 Bausch & Lomb composiÇço, e, uso de um agonista do receptor de glucocorticàide dissociado (digra), uma prà-droga do mesmo, ou um sal farmaceuticamente aceitÁvel do mesmo
US20080057022A1 (en) * 2006-08-30 2008-03-06 Erning Xia Ophthalmic Pharmaceutical Compositions and Uses Thereof
US8138156B2 (en) * 2006-10-18 2012-03-20 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
US20080095754A1 (en) * 2006-10-18 2008-04-24 Burke Susan E Ophthalmic compositions comprising diglycine
US20080095863A1 (en) * 2006-10-24 2008-04-24 Alcon Manufacturing Ltd. 2-pyrrolidone derivatives for preservation of ophthalmic, otic and nasal compositions
WO2008052037A2 (en) * 2006-10-24 2008-05-02 Alcon Research, Ltd. Packaging materials for formulations containing 2-pyrrolidone derivatives
US20080188573A1 (en) * 2007-02-02 2008-08-07 Alcon Research, Ltd. Use of thy1-fp transgenic mouse for the identification of ophthalmic agents
WO2008120249A1 (en) * 2007-03-30 2008-10-09 Sifi S.P.A. Pharmaceutical formulations based on apolar and polar lipids for ophthalmic use
CN101674807B (zh) * 2007-05-04 2013-03-20 博士伦公司 用于缓解、改善、治疗或预防干眼症的组合物及其制备和使用方法
KR20100016285A (ko) * 2007-05-07 2010-02-12 보오슈 앤드 롬 인코포레이팃드 안구건조 상태를 감소, 개선, 치료 또는 예방하기 위한 조성물 및 이의 제조 및 사용 방법
WO2008154129A1 (en) * 2007-06-08 2008-12-18 Bausch & Lomb Incorporated Pharmaceutical compositions and method for treating, reducing, ameliorating, alleviating, or preventing dry eye
US20090142292A1 (en) * 2007-12-03 2009-06-04 Blackwell Richard I Method For The Mitigation of Symptoms of Dry Eye
US8629099B2 (en) * 2008-03-25 2014-01-14 Bausch & Lomb Incorporated Ophthalmic compositions comprising a dipeptide
BRPI0918139B1 (pt) 2008-09-10 2024-04-30 Ptc Therapeutics, Inc Composição, alimento medicinal ou funcional, suplemento alimentar ou dietético para tratamento de distúrbios de desenvolvimento pervasivos com terapêuticos redox-ativos
EP2346513A1 (de) * 2008-09-15 2011-07-27 Bausch & Lomb Incorporated Zusammensetzungen mit polymeren mit aminozuckereinheiten und verfahren zu ihrer herstellung und verwendung
US8539938B2 (en) * 2009-03-12 2013-09-24 Ford Global Technologies, Llc Fuel systems and methods for controlling fuel systems in a vehicle with multiple fuel tanks
JP2012525399A (ja) 2009-04-28 2012-10-22 エジソン ファーマシューティカルズ， インコーポレイテッド トコトリエノールキノンを用いる、レーバー遺伝性視神経症および優性遺伝性視神経萎縮症の治療
TWI478730B (zh) * 2009-12-03 2015-04-01 Alcon Res Ltd 眼科乳劑
US8658614B2 (en) 2010-08-13 2014-02-25 The University of Texas Health Science Center Aptamer-containing compositions and methods for targeting E-selectin
US9161531B2 (en) 2011-02-23 2015-10-20 Donald R. Korb High alcohol content sanitizer
US8859525B2 (en) 2011-07-19 2014-10-14 Bausch & Lomb Incorporated Pharmaceutical compositions comprising mushroom-based polysaccharides and uses thereof
EP2758031A1 (de) 2011-09-22 2014-07-30 Bausch & Lomb Incorporated Ophthalmische gelzusammensetzungen
US8324171B1 (en) 2012-02-06 2012-12-04 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
US8664180B2 (en) 2012-02-06 2014-03-04 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
US9278132B2 (en) 2012-02-13 2016-03-08 Bausch & Lomb Incorporated Ophthalmic pharmaceutical compositions and methods of making and using same
EP2816996B1 (de) 2012-02-24 2016-10-05 Bausch & Lomb Incorporated Ophthalmische zusammensetzungen mit alkoxylierten natürlichen wachsen
JP6016465B2 (ja) * 2012-06-12 2016-10-26 ロート製薬株式会社 ビタミンａ類を含有する水性組成物
ES2994608T3 (en) 2012-08-10 2025-01-27 Osio Corp D/B/A Yolia Health Contact lens use in the treatment of an ophthalmologic condition
PL2948196T3 (pl) 2013-01-24 2018-01-31 Bausch & Lomb Poli(azotowane/aminowane) pochodne naturalnego wosku lub jego alkoksylowana pochodna i kompozycje okulistyczne
AU2015229452B2 (en) 2014-03-12 2021-07-15 University Of Virginia Patent Foundation Compositions and methods for treating eye infections and disease
US9505709B2 (en) 2014-05-05 2016-11-29 Thetis Pharmaceuticals Llc Compositions and methods relating to ionic salts of peptides
KR20170023061A (ko) 2014-06-18 2017-03-02 테티스 파마수티컬스 엘엘씨 활성제의 미네랄 아미노산 복합체
WO2017079734A1 (en) 2015-11-05 2017-05-11 University Of Louisville Research Foundation, Inc. Local and regional anesthesia and analgesia
CN113024369A (zh) 2015-12-17 2021-06-25 Ptc医疗公司 用于治疗氧化应急障碍的化合物
CA3026264A1 (en) 2016-06-03 2017-12-07 Thetis Pharmaceuticals Llc Compositions and methods relating to salts of specialized pro-resolving mediators
US9981041B2 (en) 2016-08-23 2018-05-29 Ira Jason Salzman Ophthalmic lubricating spray
US12233017B2 (en) 2016-10-14 2025-02-25 Olympic Ophthalmics, Inc. Quiet handheld devices and methods for treatment of disorders
US20180296390A1 (en) * 2017-04-18 2018-10-18 David Hoare Apparatus and method for treating a number of eye conditions of a user including dry eye syndrome and/or burns to the eyes
TWI884130B (zh) 2018-02-21 2025-05-21 瑞士商愛爾康公司 基於脂質的眼用乳劑
US11141348B2 (en) 2018-02-26 2021-10-12 Olympic Ophthalmics, Inc. Treatment methods using handheld devices for disorders
US11278493B2 (en) 2018-12-10 2022-03-22 EternaTear, Inc. Ophthalmic formulations providing durable ocular lubrication
US11679078B1 (en) 2022-03-08 2023-06-20 EternaTear, Inc. Ophthalmic formulations and related methods
US11471475B1 (en) 2022-03-08 2022-10-18 Ralph P. Stone Ophthalmic suspension vehicles and related methods for pharmaceutical ingredient delivery

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4677099A (en) * 1981-09-04 1987-06-30 Yeda Research And Development Co., Ltd. Medical processes employing a novel lipid fraction
US4421748A (en) * 1982-07-13 1983-12-20 Trager Seymour F Artificial tear aid
WO1988000824A1 (en) * 1986-07-28 1988-02-11 Liposome Technology, Inc. Liposomes with enhanced retention on mucosal tissue
US4839175A (en) * 1986-07-28 1989-06-13 Liposome Technology, Inc. Liposomes with enhanced retention on mucosal tissue
US4804539A (en) * 1986-07-28 1989-02-14 Liposome Technology, Inc. Ophthalmic liposomes
US4818537A (en) * 1986-10-21 1989-04-04 Liposome Technology, Inc. Liposome composition for treating dry eye
US4914088A (en) * 1987-04-02 1990-04-03 Thomas Glonek Dry eye treatment solution and method
US4866049A (en) * 1987-08-10 1989-09-12 Spectra Pharmaceutical Services, Inc. Ophthalmic compositionn and method of using same
AU614465B2 (en) * 1989-04-05 1991-08-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions

Also Published As

Publication number Publication date
RU2092138C1 (ru) 1997-10-10
JPH04279525A (ja) 1992-10-05
DE69115990T2 (de) 1996-05-30
TW200396B (de) 1993-02-21
ES2084722T3 (es) 1996-05-16
US5294607A (en) 1994-03-15
AU7619191A (en) 1992-08-06
JP3281392B2 (ja) 2002-05-13
CA2043366C (en) 1999-01-05
EP0459148A2 (de) 1991-12-04
EP0459148A3 (en) 1992-10-14
IL98237A (en) 1996-08-04
DE69115990D1 (de) 1996-02-15
CA2043366A1 (en) 1991-11-30
GR3019478T3 (en) 1996-07-31
EP0459148B1 (de) 1996-01-03
IL98237A0 (en) 1992-06-21
AU648304B2 (en) 1994-04-21

Similar Documents

Publication Publication Date Title
DE69115990D1 (de) Zusammensetzung zur Behandlung von Dry Eye Erkrankungen
DE3874479D1 (de) Loesung zur behandlung von "dry-eye"-erkrankungen.
DE4391418T1 (de) Vorrichtung zur elektrochemischen Behandlung von Wasser
ATE60697T1 (de) Verfahren zur bekaempfung von pilzen.
ATE190224T1 (de) Tensidefreie wasser-in-öl emulsion
DE69432228D1 (de) Fluorierte öl-in-wasser-emulsion zur oberflächenbehandlung
DE69022249D1 (de) Knochenwachsapplikator zur Behandlung von Knochengewebe.
DE69609868D1 (de) Neue steroidester zur behandlung von hauterkrankungen
DE3674308D1 (de) Biozide zusammensetzungund verfahren zur behandlung von wasser.
DE69512509D1 (de) Eigenschaften von Gesichtpheromonen von Katzen
DK526489D0 (da) Bademiddel
DE69126776D1 (de) Parasitizide zusammensetzung und verfahren zu ihrer herstellung und ihre verwendung
DE69404785D1 (de) Vorrichtung zur Behandlung von Oberflächen
BE888082A (fr) Compositions cosmetiques ou pharmaceutiques sous forme d'emulsions stables du type huile-dans-l'eau
DE68914657D1 (de) Vorrichtung zur herstellung von eiskugeln und anwendung derselben zwecks oberflächenbehandlung.
DE69314234D1 (de) Konservierte Polysiloxanemulsion zur Behandlung von Geweben
DE59106539D1 (de) Verfahren zur Oberflächenbehandlung von Bauteilen.
ATE106736T1 (de) Verwendung von dimethylpolysiloxan zur behandlung von erkrankungen des gastrointestinaltraktes.
IT7924778A0 (it) Procedimento per l'innesto di particelle di gomma dienica in emulsione.
EP0844017A4 (de) Prozess zur herstellung eines emulgators und emulgierte zusammensetzung
DE69403871D1 (de) Vorrichtung zur Behandlung von Oberflächen
SE8802873D0 (sv) A method of controlling microbiological deposits on paper making equipment and paper obtained thereby
DE69412178D1 (de) Apparat zur Behandlung von Lagen
DE68903930D1 (de) Lipidemulsion zur behandlung von aids.
ATE204337T1 (de) Verfahren zur behandlung von leder mit tensiden zur verbesserung der hydrophobierwirkung

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee