ATE452882T1 - Herstellung von quetiapin - Google Patents

Herstellung von quetiapin

Info

Publication number
ATE452882T1
ATE452882T1 AT04767074T AT04767074T ATE452882T1 AT E452882 T1 ATE452882 T1 AT E452882T1 AT 04767074 T AT04767074 T AT 04767074T AT 04767074 T AT04767074 T AT 04767074T AT E452882 T1 ATE452882 T1 AT E452882T1
Authority
AT
Austria
Prior art keywords
quetiapine
preparation
compound
discloses
well
Prior art date
Application number
AT04767074T
Other languages
English (en)
Inventor
Petteri Rummakko
Soini Huhta
Arne Grumann
Original Assignee
Fermion Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fermion Oy filed Critical Fermion Oy
Application granted granted Critical
Publication of ATE452882T1 publication Critical patent/ATE452882T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D281/16—[b, f]-condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT04767074T 2003-09-23 2004-09-23 Herstellung von quetiapin ATE452882T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50498103P 2003-09-23 2003-09-23
PCT/FI2004/000560 WO2005028458A1 (en) 2003-09-23 2004-09-23 Preparation of quetiapine

Publications (1)

Publication Number Publication Date
ATE452882T1 true ATE452882T1 (de) 2010-01-15

Family

ID=34375548

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04767074T ATE452882T1 (de) 2003-09-23 2004-09-23 Herstellung von quetiapin

Country Status (9)

Country Link
US (1) US7863441B2 (de)
EP (1) EP1664007B1 (de)
JP (1) JP2007505864A (de)
AT (1) ATE452882T1 (de)
CA (1) CA2538745A1 (de)
DE (1) DE602004024798D1 (de)
ES (1) ES2335589T3 (de)
PT (1) PT1664007E (de)
WO (1) WO2005028458A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2538866A1 (en) * 2003-09-23 2005-03-31 Fermion Oy Preparation of quetiapine
US7687622B2 (en) 2005-04-14 2010-03-30 Teva Pharmaceutical Industries, Ltd Process for preparing quetiapine fumarate
PT103884A (pt) * 2006-11-17 2008-05-19 Astrazeneca Ab Composições de libertação prolongada e métodos para a sua preparação
WO2009004480A2 (en) 2007-05-07 2009-01-08 Actavis Group Ptc Ehf Quetiapine salts and their polymorphs
JP2011510960A (ja) 2008-01-31 2011-04-07 フェルミオン オサケ ユキチュア ケチアピンの製造方法
WO2010100623A1 (en) 2009-03-04 2010-09-10 Ranbaxy Laboratories Limited Process for the preparation of quetiapine fumarate
CN101891707B (zh) * 2010-07-29 2012-10-17 浙江海正药业股份有限公司 喹硫平或其可药用盐的制备方法
EP2888284B1 (de) 2012-08-21 2022-07-06 Janssen Pharmaceutica NV Antikörper gegen risperidon-haptene und verwendungen davon
PL2888257T3 (pl) * 2012-08-21 2018-02-28 Janssen Pharmaceutica Nv Hapteny kwetiapiny do zastosowania w testach immunologicznych
WO2014031656A1 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc Antibodies to olanzapine haptens and use thereof
JP6389176B2 (ja) 2012-08-21 2018-09-12 ヤンセン ファーマシューティカ エヌ．ベー． アリピプラゾールハプテンに対する抗体及びその使用
CA2882562C (en) 2012-08-21 2019-08-27 Eric Hryhorenko Antibodies to aripiprazole and use thereof
CA2882596C (en) 2012-08-21 2019-05-14 Ortho-Clinical Diagnostics, Inc. Antibodies to olanzapine and use thereof
ES2691092T3 (es) 2012-08-21 2018-11-23 Janssen Pharmaceutica Nv Anticuerpos contra la risperidona y uso de los mismos
JP6450314B2 (ja) 2012-08-21 2019-01-09 ヤンセン ファーマシューティカ エヌ．ベー． クエチアピンハプテンに対する抗体及びその使用
PL2888592T3 (pl) 2012-08-21 2018-03-30 Janssen Pharmaceutica Nv Przeciwciała względem kwetiapiny i ich zastosowania
JP2015529199A (ja) 2012-08-21 2015-10-05 オルソ−クリニカル ダイアグノスティクス，インコーポレイティド パリペリドンハプテンに対する抗体及びその使用
JP6131414B2 (ja) 2012-08-21 2017-05-24 ヤンセン ファーマシューティカ エヌ．ベー． アリピプラゾールのハプテン及びイムノアッセイにおけるそれらの使用
ES2669565T3 (es) 2012-08-21 2018-05-28 Janssen Pharmaceutica Nv Haptenos de risperidona y paliperidona
CN104854110B (zh) * 2012-08-21 2016-12-28 詹森药业有限公司 奥氮平半抗原
JP2015527365A (ja) 2012-08-21 2015-09-17 オルソ−クリニカル ダイアグノスティクス，インコーポレイティド パリペリドンに対する抗体及びその使用
CN104837838A (zh) 2012-08-21 2015-08-12 詹森药业有限公司 帕潘立酮半抗原
CN103396382B (zh) * 2013-07-29 2015-05-20 太仓市茜泾化工有限公司 一种喹硫平中间体的制备方法
CN104803947A (zh) * 2015-03-12 2015-07-29 常州康丽制药有限公司 11-(1-哌嗪基)二苯并[b,f][1,4]硫氮杂*富马酸盐的制备方法
EP3390449A1 (de) 2015-12-17 2018-10-24 Janssen Pharmaceutica N.V. Antikörper gegen risperidon und verwendung davon
US10435478B2 (en) 2015-12-17 2019-10-08 Janssen Pharmaceutica Nv Antibodies to quetiapine and use thereof
CN114181172B (zh) * 2021-12-27 2023-12-22 浙江苏泊尔制药有限公司 一种富马酸喹硫平的高效制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA979441A (en) * 1967-02-27 1975-12-09 American Cyanamid Company 11-(piperazinyl) dibenz (b,f) (1,4) oxazepines and analogous thiazepines
US3539573A (en) * 1967-03-22 1970-11-10 Jean Schmutz 11-basic substituted dibenzodiazepines and dibenzothiazepines
HU227039B1 (en) * 2000-01-25 2010-05-28 Egis Gyogyszergyar Nyilvanosan New process for the production of quetiapine and intermediates therefor
CN1289471C (zh) * 2001-04-16 2006-12-13 先灵公司 作为cxc－趋化因子受体配体的3,4－二取代的环丁烯－1,2－二酮
ES2223294B2 (es) * 2003-08-08 2005-10-01 Vita Cientifica, S.L. Procedimiento de preparacion de un compuesto farmaceuticamente activo.
CA2538866A1 (en) 2003-09-23 2005-03-31 Fermion Oy Preparation of quetiapine

Also Published As

Publication number Publication date
PT1664007E (pt) 2010-02-15
JP2007505864A (ja) 2007-03-15
EP1664007B1 (de) 2009-12-23
EP1664007A1 (de) 2006-06-07
DE602004024798D1 (de) 2010-02-04
US7863441B2 (en) 2011-01-04
WO2005028458A1 (en) 2005-03-31
CA2538745A1 (en) 2005-03-31
US20070111987A1 (en) 2007-05-17
ES2335589T3 (es) 2010-03-30

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