ATE398121T1 - Neue synthese von irbesartan - Google Patents

Neue synthese von irbesartan

Info

Publication number: ATE398121T1
Authority: AT; Austria
Prior art keywords: irbesartan; new synthesis; synthesis; new; provides
Prior art date: 2003-01-16

Application number

AT04702955T

Other languages

English (en)

Inventor

Gennady Nisnevich

Igor Rukhman

Boris Pertsikov

Julia Kaftanov

Ben-Zion Dolitzky

Original Assignee

Teva Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-01-16

Filing date

2004-01-16

Publication date

2008-07-15

2004-01-16 Application filed by Teva Pharma filed Critical Teva Pharma

2008-07-15 Application granted granted Critical

2008-07-15 Publication of ATE398121T1 publication Critical patent/ATE398121T1/de

Links

239000002947 C09CA04 - Irbesartan Substances 0.000 title abstract 2
YCPOHTHPUREGFM-UHFFFAOYSA-N irbesartan Chemical compound O=C1N(CC=2C=CC(=CC=2)C=2C(=CC=CC=2)C=2[N]N=NN=2)C(CCCC)=NC21CCCC2 YCPOHTHPUREGFM-UHFFFAOYSA-N 0.000 title abstract 2
229960002198 irbesartan Drugs 0.000 title abstract 2
230000015572 biosynthetic process Effects 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1
238000004519 manufacturing process Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Plural Heterocyclic Compounds (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Catalysts (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT04702955T 2003-01-16 2004-01-16 Neue synthese von irbesartan ATE398121T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US44099703P	2003-01-16	2003-01-16

Publications (1)

Publication Number	Publication Date
ATE398121T1 true ATE398121T1 (de)	2008-07-15

Family

ID=32771889

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04702955T ATE398121T1 (de)	2003-01-16	2004-01-16	Neue synthese von irbesartan

Country Status (10)

Country	Link
US (6)	US7019148B2 (de)
EP (3)	EP1509517B1 (de)
CN (2)	CN1759113A (de)
AT (1)	ATE398121T1 (de)
CA (1)	CA2513373A1 (de)
DE (1)	DE602004014321D1 (de)
ES (1)	ES2281312T3 (de)
PT (1)	PT1509517E (de)
SI (1)	SI1509517T1 (de)
WO (1)	WO2004065383A2 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7941149B2 (en)	2002-05-13	2011-05-10	Misonimo Chi Acquistion L.L.C.	Multi-hop ultra wide band wireless network communication
US8780770B2 (en) *	2002-05-13	2014-07-15	Misonimo Chi Acquisition L.L.C.	Systems and methods for voice and video communication over a wireless network
US7957356B2 (en) *	2002-05-13	2011-06-07	Misomino Chi Acquisitions L.L.C.	Scalable media access control for multi-hop high bandwidth communications
CN1759113A (zh) *	2003-01-16	2006-04-12	特瓦制药工业有限公司	伊贝沙坦的新合成方法
US7038060B2 (en) *	2003-02-05	2006-05-02	Teva Pharmaceutical Industries Ltd.	Synthesis of 2-butyl-3-(2′-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)-1,3-diazaspiro[4.4]-non-ene-4-one
WO2005113518A1 (en) *	2004-05-20	2005-12-01	Dr. Reddy's Laboratories Ltd.	Process for preparing irbesartan
TWI346108B (en) *	2004-08-23	2011-08-01	Bristol Myers Squibb Co	A method for preparing irbesartan and intermediates thereof
DE102004060699A1 (de) *	2004-12-16	2006-06-22	Ratiopharm Gmbh	Verfahren zur Herstellung von Candesartan
ES2308591T3 (es) *	2004-12-22	2008-12-01	Algry Quimica, S.L	Intermedios para la preparacion de antagonistas de los receptores de la angiotensina ii.
SI21965A (sl) *	2005-01-05	2006-08-31	Krka, Tovarna Zdravil, D.D., Novo Mesto	Priprava tetrazolskega derivata
ES2259909B1 (es) *	2005-02-28	2007-06-16	Inke, S.A.	Procedimiento para la obtencion de un compuesto farmaceuticamente activo y de su intermedio de sintesis.
EP1885714B1 (de) *	2005-05-24	2014-01-15	LEK Pharmaceuticals d.d.	Verfahren zur herstellung von 2-alkyl-1-((2'-substituierten-biphenyl-4-yl)methyl)-imidazol, -dihydroimidazol oder -benzimidazol-derivaten
EP1749828A1 (de)	2005-08-04	2007-02-07	Farmaprojects S.L.	Verfahren zur Herstellung eines Angiotensin-II-Antagonisten
EP1764365A1 (de) *	2005-09-20	2007-03-21	KRKA, D.D., Novo Mesto	Verfahren zur Herstellung Sartanderivate und Zwischenprodukte für dieses Verfahren
EP1948641A1 (de) *	2005-10-28	2008-07-30	Alembic Limited	Verbessertes verfahren zur herstellung von irbesartan
ES2300175B1 (es) *	2006-02-14	2009-06-08	Inke, S.A.	Procedimiento para la obtencion de intermedios utiles en la obtencion de un compuesto farmaceuticamente activo.
CA2654218C (en)	2006-04-07	2014-07-22	Lek Pharmaceuticals D.D.	Process for the preparation of pure irbesartan
US8175613B2 (en)	2006-08-04	2012-05-08	Misonimo Chi Acquisitions L.L.C.	Systems and methods for determining location of devices within a wireless network
JP2009515834A (ja) *	2006-08-29	2009-04-16	テバファーマシューティカルインダストリーズリミティド	５−フェニル−１−トリチル−１ｈ−テトラゾールの合成のための方法
CN101611571B (zh) *	2006-12-07	2013-04-03	米索尼莫奇获取有限公司	时隙和信道分配系统和方法
CA2759163C (en)	2009-04-28	2015-02-17	Daiichi Sankyo Company, Limited	Method for producing olmesartan medoxomil
CN106608886A (zh) *	2015-11-22	2017-05-03	宁夏际华环境安全科技有限公司	一种苯基硼酸生产工艺

Family Cites Families (15)

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Publication number	Priority date	Publication date	Assignee	Title
US531929A (en) *		1895-01-01		harden
GB8910547D0 (en) *	1989-05-08	1989-06-21	Ici America Inc	Substituted ketones
US5270317A (en)	1990-03-20	1993-12-14	Elf Sanofi	N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
US5164403A (en)	1991-04-05	1992-11-17	G. D. Searle & Co.	N-arylheteroarylalkyl imidazol-2-one compounds for treatment of circulatory disorders
CZ36394A3 (en)	1991-08-19	1994-07-13	Du Pont	Substituted imidazilonone derivatives and pharmaceutical preparations based thereon
US5310929A (en)	1992-08-06	1994-05-10	E. I. Du Pont De Nemours And Company	Prodrugs of imidazole carboxylic acids as angiotensin II receptor antagonists
CA2147503A1 (en)	1992-11-06	1994-05-26	Judith M. Pisano	Substituted dipeptide analogs promote release of growth hormone
US5541209A (en)	1994-08-22	1996-07-30	Bristol-Myers Squibb Company	Method of treating or preventing cardiac arrhythmia employing an N-substituted heterocyclic derivative
ATE176784T1 (de) *	1994-09-20	1999-03-15	Wakunaga Seiyaku Kk	Verfahren zur herstellung von n- biphenylmethylthiadiazolin derivaten oder deren salzen sowie dafür benötigte zwischen verbindungen
FR2725987B1 (fr)	1994-10-19	1997-01-10	Sanofi Sa	Procede pour la preparation d'un derive de tetrazole sous deux formes cristallines et nouvelle forme cristalline de ce derive
US5541204A (en) *	1994-12-02	1996-07-30	Bristol-Myers Squibb Company	Aryloxypropanolamine β 3 adrenergic agonists
IT1292437B1 (it) *	1997-06-30	1999-02-08	Zambon Spa	Processo di orto-metallazione utile per la sintesi di 1 - tetrazol- 5-il) benzeni 2-sostituiti
FR2780403B3 (fr) *	1998-06-24	2000-07-21	Sanofi Sa	Nouvelle forme de l'irbesartan, procedes pour obtenir ladite forme et compositions pharmaceutiques en contenant
AU2003256609A1 (en) *	2002-07-16	2004-02-02	Teva Pharmaceutical Industries Ltd.	Novel synthesis of irbesartan
CN1759113A (zh) *	2003-01-16	2006-04-12	特瓦制药工业有限公司	伊贝沙坦的新合成方法

2004
- 2004-01-16 CN CNA2004800067788A patent/CN1759113A/zh active Pending
- 2004-01-16 EP EP04702955A patent/EP1509517B1/de not_active Expired - Lifetime
- 2004-01-16 SI SI200430833T patent/SI1509517T1/sl unknown
- 2004-01-16 PT PT04702955T patent/PT1509517E/pt unknown
- 2004-01-16 ES ES04702955T patent/ES2281312T3/es not_active Expired - Lifetime
- 2004-01-16 AT AT04702955T patent/ATE398121T1/de not_active IP Right Cessation
- 2004-01-16 EP EP09180682A patent/EP2189457A1/de not_active Withdrawn
- 2004-01-16 US US10/759,906 patent/US7019148B2/en not_active Expired - Fee Related
- 2004-01-16 CN CNA2007101866764A patent/CN101165062A/zh active Pending
- 2004-01-16 EP EP08010340A patent/EP2039693A3/de not_active Withdrawn
- 2004-01-16 DE DE602004014321T patent/DE602004014321D1/de not_active Expired - Fee Related
- 2004-01-16 CA CA002513373A patent/CA2513373A1/en not_active Abandoned
- 2004-01-16 WO PCT/US2004/001135 patent/WO2004065383A2/en not_active Ceased
2006
- 2006-02-06 US US11/348,945 patent/US7217825B2/en not_active Expired - Fee Related
- 2006-02-06 US US11/349,360 patent/US7227026B2/en not_active Expired - Fee Related
- 2006-02-06 US US11/348,944 patent/US7301035B2/en not_active Expired - Fee Related
2007
- 2007-05-04 US US11/800,332 patent/US7838683B2/en not_active Expired - Fee Related
2008
- 2008-12-18 US US12/317,216 patent/US20090216026A1/en not_active Abandoned

Also Published As

Publication number	Publication date
WO2004065383A2 (en)	2004-08-05
CN1759113A (zh)	2006-04-12
US7227026B2 (en)	2007-06-05
US7301035B2 (en)	2007-11-27
US7217825B2 (en)	2007-05-15
ES2281312T3 (es)	2008-08-01
WO2004065383A3 (en)	2004-12-16
EP2039693A3 (de)	2009-06-17
ES2281312T1 (es)	2007-10-01
US7019148B2 (en)	2006-03-28
US20060135544A1 (en)	2006-06-22
US20060128968A1 (en)	2006-06-15
EP2189457A1 (de)	2010-05-26
PT1509517E (pt)	2008-08-05
EP2039693A2 (de)	2009-03-25
US7838683B2 (en)	2010-11-23
SI1509517T1 (sl)	2008-10-31
EP1509517A2 (de)	2005-03-02
CN101165062A (zh)	2008-04-23
US20060135780A1 (en)	2006-06-22
US20090216026A1 (en)	2009-08-27
US20040192713A1 (en)	2004-09-30
EP1509517B1 (de)	2008-06-11
DE602004014321D1 (de)	2008-07-24
US20070213539A1 (en)	2007-09-13
CA2513373A1 (en)	2004-08-05

Legal Events

Date	Code	Title	Description
2008-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE602004014321D1 (de)	2008-07-24	Neue synthese von irbesartan
CY1109088T1 (el)	2014-07-02	Μεθοδος για την παρασκευη υποκατεστημενων ενωσεων 3-αρυλο-βουτυλ-αμινης
DK1838677T3 (da)	2010-01-11	Krystallinske former af (R)-8-chlor-1.methyl-2,3,4,5-tetrahydro-1H-3-benzazepinhydrochlorid
DE602004030334D1 (de)	2011-01-13	Synthese von 5-substituierten 7-azaindolen und 7-azaindolinen
DE602004024798D1 (de)	2010-02-04	Herstellung von quetiapin
TW200510301A (en)	2005-03-16	Novel compounds
TW200510303A (en)	2005-03-16	Novel compounds
ES2338590T3 (es)	2010-05-10	Procedimiento regioselectivo de preparacion de benzoimidazoltiofenos.
MXPA05011962A (es)	2006-02-02	Oxiarenos substituidos.
HRP20080057T3 (en)	2008-02-29	9,10-alpha,alpha-oh-taxane analogs and methods for production thereof
DE602006017918D1 (de)	2010-12-16	Verfahren zur Herstellung von Telmisartan
IS8122A (is)	2005-11-10	Aðferð til að framleiða N-útskipt 2-sýanópýrrólídín
CY1110047T1 (el)	2015-01-14	Μεθοδοι για τον καθαρισμο ραδιοεπισημασμενων προϊοντων χρησιμοποιωντας σαρωτη στερεου-υποστρωματος
NO20053151D0 (no)	2005-06-28	Fremgangsmate for a produsere mikrosystemer.
DE602006005349D1 (de)	2009-04-09	Verfahren zur herstellung von hydrazon-derivaten
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BR0214445B1 (pt)	2012-07-10	processos para a produção de compostos.
EP1485498A4 (de)	2006-09-13	Synthese von synthonen zur herstellung bioaktiver verbindungen
DK1339703T3 (da)	2004-09-27	Fremgangsmåde til fremstilling af paclitaxel
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DK1280752T3 (da)	2004-11-01	Fremgangsmåde til fremstilling af 2-alkyl-3-chlorphenoler
DE602006003204D1 (de)	2008-11-27	Reinigungsverfahren von Moxonidine
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