ATE453380T1 - Verabreichung von in lipidvesikeln verpackten kleinen hydrophilen molekülen - Google Patents
Verabreichung von in lipidvesikeln verpackten kleinen hydrophilen molekülenInfo
- Publication number
- ATE453380T1 ATE453380T1 AT02743969T AT02743969T ATE453380T1 AT E453380 T1 ATE453380 T1 AT E453380T1 AT 02743969 T AT02743969 T AT 02743969T AT 02743969 T AT02743969 T AT 02743969T AT E453380 T1 ATE453380 T1 AT E453380T1
- Authority
- AT
- Austria
- Prior art keywords
- administration
- lipid vesicles
- hydrophilic molecules
- small hydrophilic
- molecules packaged
- Prior art date
Links
- 150000002632 lipids Chemical class 0.000 title abstract 3
- 150000002433 hydrophilic molecules Chemical class 0.000 title 1
- 150000003384 small molecules Chemical class 0.000 abstract 3
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01202401A EP1269993A1 (de) | 2001-06-21 | 2001-06-21 | Verabreichung von in Lipidvesikeln verpackten kleinen hydrophilen Molekülen |
| PCT/NL2002/000412 WO2003000233A2 (en) | 2001-06-21 | 2002-06-21 | Delivery of small hydrophilic molecules packaged into lipid vesicles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE453380T1 true ATE453380T1 (de) | 2010-01-15 |
Family
ID=8180516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02743969T ATE453380T1 (de) | 2001-06-21 | 2002-06-21 | Verabreichung von in lipidvesikeln verpackten kleinen hydrophilen molekülen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20030118636A1 (de) |
| EP (2) | EP1269993A1 (de) |
| AT (1) | ATE453380T1 (de) |
| CA (1) | CA2451148A1 (de) |
| DE (1) | DE60234921D1 (de) |
| DK (1) | DK1397123T3 (de) |
| WO (1) | WO2003000233A2 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1412487T3 (da) | 2001-07-30 | 2010-08-30 | Meso Scale Technologies Llc | Assayelektroder der har immobiliserede lipid/proteinlag og fremgangsmåder til at fremstille og anvende disse |
| JP2005530704A (ja) * | 2002-03-05 | 2005-10-13 | トランセイブ, インク. | 細胞内感染を予防及び治療するための吸入システム |
| EP3427742B1 (de) * | 2002-10-29 | 2020-08-12 | Insmed Incorporated | Aminoglycosid enthaltende liposome zur behandlung von pulmonaren infektionen |
| US7718189B2 (en) | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
| US7879351B2 (en) * | 2002-10-29 | 2011-02-01 | Transave, Inc. | High delivery rates for lipid based drug formulations, and methods of treatment thereof |
| US7968115B2 (en) * | 2004-03-05 | 2011-06-28 | Board Of Regents, The University Of Texas System | Liposomal curcumin for treatment of cancer |
| US7459147B2 (en) | 2003-06-30 | 2008-12-02 | L'oreal | Cosmetic composition comprising at least one hydrophilic organopolysiloxane, at least one hydrocarbon oil and at least one short hydrocarbon ester |
| US8784881B2 (en) * | 2004-03-05 | 2014-07-22 | Board Of Regents, The University Of Texas System | Liposomal curcumin for treatment of diseases |
| US20080103213A1 (en) * | 2004-03-05 | 2008-05-01 | Board Of Regents, The University Of Texas System | Liposomal curcumin for treatment of neurofibromatosis |
| ES2798263T3 (es) | 2005-12-08 | 2020-12-10 | Insmed Inc | Composiciones a base de lípidos de antiinfecciosos para tratar infecciones pulmonares |
| US20100196455A1 (en) * | 2007-05-04 | 2010-08-05 | Transave, Inc. | Compositions of Multicationic Drugs for Reducing Interactions with Polyanionic Biomolecules and Methods of Use Thereof |
| US9333214B2 (en) | 2007-05-07 | 2016-05-10 | Insmed Incorporated | Method for treating pulmonary disorders with liposomal amikacin formulations |
| US9114081B2 (en) | 2007-05-07 | 2015-08-25 | Insmed Incorporated | Methods of treating pulmonary disorders with liposomal amikacin formulations |
| US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
| US20100189777A1 (en) * | 2007-07-20 | 2010-07-29 | Basf Se | Functionalized nanocompartments with a transport system |
| EP2127640A1 (de) | 2008-05-27 | 2009-12-02 | Koninklijke Philips Electronics N.V. | Modifizierte azid-enthaltende Proteine |
| US9345113B2 (en) | 2009-06-24 | 2016-05-17 | Koninklijke Philips N.V. | Method and device for programming a microcontroller |
| WO2011097480A1 (en) * | 2010-02-05 | 2011-08-11 | University Of Louisville Research Foundation, Inc. | Exosomal compositions and methods for the treatment of disease |
| ES2905368T3 (es) | 2012-05-21 | 2022-04-08 | Insmed Inc | Sistemas para el tratamiento de infecciones pulmonares |
| WO2014081300A1 (en) * | 2012-11-22 | 2014-05-30 | Tagworks Pharmaceuticals B.V. | Channel protein activatable liposomes |
| WO2014085526A1 (en) | 2012-11-29 | 2014-06-05 | Insmed Incorporated | Stabilized vancomycin formulations |
| KR102205278B1 (ko) | 2013-03-14 | 2021-01-22 | 다이서나 파마수이티컬, 인크. | 음이온성 약제를 제형화하는 방법 |
| PL3142643T3 (pl) | 2014-05-15 | 2019-12-31 | Insmed Incorporated | Sposoby leczenia zakażeń płuc prątkami niegruźliczymi |
| EP3773505A4 (de) | 2018-03-30 | 2021-12-22 | Insmed Incorporated | Verfahren zur kontinuierlichen herstellung von liposomalen arzneimittelprodukten |
| AU2019262117C1 (en) | 2018-05-02 | 2024-12-05 | Insmed Incorporated | Methods for the manufacture of liposomal drug formulations |
| WO2020112408A1 (en) * | 2018-11-30 | 2020-06-04 | Corning Incorporated | System and method for analyzing extracellular vesicles with an optical biosensor |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4900556A (en) * | 1985-04-26 | 1990-02-13 | Massachusetts Institute Of Technology | System for delayed and pulsed release of biologically active substances |
| US5252263A (en) * | 1986-06-16 | 1993-10-12 | The Liposome Company, Inc. | Induction of asymmetry in vesicles |
| DE3852036T2 (de) * | 1987-07-27 | 1995-03-09 | Commonwealth Scientific And Industrial Research Organization, Campbell | Rezeptormembranen. |
| US5227470A (en) * | 1988-08-26 | 1993-07-13 | Canon Kabushiki Kaisha | Method for forming proteoliposome and method for forming giant proteoliposome |
| US5874316A (en) * | 1989-01-27 | 1999-02-23 | Australian Membrane Biotechnology Research Institute | Receptor membranes and ionophore gating |
| EP0770874A3 (de) * | 1989-01-27 | 1998-01-21 | Australian Membrane And Biotechnology Research Institute | Rezeptormembranen und selektive Steuerung des Ionenflusses durch Ionophoren |
| US5753258A (en) * | 1990-10-19 | 1998-05-19 | University Of Florida | Artificial viral envelopes |
| US5252348A (en) * | 1990-10-19 | 1993-10-12 | Univ. Of Florida Research Foundation, Inc. | Artificial viral envelopes |
| US5820879A (en) * | 1993-02-12 | 1998-10-13 | Access Pharmaceuticals, Inc. | Method of delivering a lipid-coated condensed-phase microparticle composition |
| US5753261A (en) * | 1993-02-12 | 1998-05-19 | Access Pharmaceuticals, Inc. | Lipid-coated condensed-phase microparticle composition |
| ES2177602T3 (es) * | 1994-11-18 | 2002-12-16 | Stichting Nl I Voor Zuivelonde | Metodo para controlar la expresion de genes en acido lactico. |
| WO1999003889A1 (en) * | 1997-07-15 | 1999-01-28 | The Regents Of The University Of California | Isolated dna encoding human calcium activated potassium channel |
| US6165732A (en) * | 1997-10-14 | 2000-12-26 | Washington University | Method for identifying apoptosis modulating compounds |
| GB9721901D0 (en) * | 1997-10-16 | 1997-12-17 | Univ Manchester | Particles |
-
2001
- 2001-06-21 EP EP01202401A patent/EP1269993A1/de not_active Withdrawn
-
2002
- 2002-06-21 EP EP02743969A patent/EP1397123B1/de not_active Expired - Lifetime
- 2002-06-21 CA CA002451148A patent/CA2451148A1/en not_active Abandoned
- 2002-06-21 WO PCT/NL2002/000412 patent/WO2003000233A2/en not_active Ceased
- 2002-06-21 AT AT02743969T patent/ATE453380T1/de not_active IP Right Cessation
- 2002-06-21 DE DE60234921T patent/DE60234921D1/de not_active Expired - Lifetime
- 2002-06-21 DK DK02743969.4T patent/DK1397123T3/da active
- 2002-10-24 US US10/281,048 patent/US20030118636A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60234921D1 (de) | 2010-02-11 |
| DK1397123T3 (da) | 2010-05-03 |
| CA2451148A1 (en) | 2003-01-03 |
| EP1397123A2 (de) | 2004-03-17 |
| EP1269993A1 (de) | 2003-01-02 |
| EP1397123B1 (de) | 2009-12-30 |
| WO2003000233A3 (en) | 2003-10-16 |
| US20030118636A1 (en) | 2003-06-26 |
| WO2003000233A2 (en) | 2003-01-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |