ATE453380T1 - Verabreichung von in lipidvesikeln verpackten kleinen hydrophilen molekülen - Google Patents
Verabreichung von in lipidvesikeln verpackten kleinen hydrophilen molekülenInfo
- Publication number
- ATE453380T1 ATE453380T1 AT02743969T AT02743969T ATE453380T1 AT E453380 T1 ATE453380 T1 AT E453380T1 AT 02743969 T AT02743969 T AT 02743969T AT 02743969 T AT02743969 T AT 02743969T AT E453380 T1 ATE453380 T1 AT E453380T1
- Authority
- AT
- Austria
- Prior art keywords
- administration
- lipid vesicles
- hydrophilic molecules
- small hydrophilic
- molecules packaged
- Prior art date
Links
- 150000002632 lipids Chemical class 0.000 title abstract 3
- 150000002433 hydrophilic molecules Chemical class 0.000 title 1
- 150000003384 small molecules Chemical class 0.000 abstract 3
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01202401A EP1269993A1 (de) | 2001-06-21 | 2001-06-21 | Verabreichung von in Lipidvesikeln verpackten kleinen hydrophilen Molekülen |
| PCT/NL2002/000412 WO2003000233A2 (en) | 2001-06-21 | 2002-06-21 | Delivery of small hydrophilic molecules packaged into lipid vesicles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE453380T1 true ATE453380T1 (de) | 2010-01-15 |
Family
ID=8180516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02743969T ATE453380T1 (de) | 2001-06-21 | 2002-06-21 | Verabreichung von in lipidvesikeln verpackten kleinen hydrophilen molekülen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20030118636A1 (de) |
| EP (2) | EP1269993A1 (de) |
| AT (1) | ATE453380T1 (de) |
| CA (1) | CA2451148A1 (de) |
| DE (1) | DE60234921D1 (de) |
| DK (1) | DK1397123T3 (de) |
| WO (1) | WO2003000233A2 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1412487B1 (de) | 2001-07-30 | 2010-06-16 | Meso Scale Technologies LLC | Assay-elektroden mit schichten aus immobilisiertem lipid/protein sowie verfahren zu deren herstellung und verwendung |
| JP2005530704A (ja) * | 2002-03-05 | 2005-10-13 | トランセイブ, インク. | 細胞内感染を予防及び治療するための吸入システム |
| US7879351B2 (en) * | 2002-10-29 | 2011-02-01 | Transave, Inc. | High delivery rates for lipid based drug formulations, and methods of treatment thereof |
| US7718189B2 (en) | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
| PT1581236E (pt) * | 2002-10-29 | 2013-12-24 | Insmed Inc | Libertação prolongada de anti-infecciosos |
| US7968115B2 (en) | 2004-03-05 | 2011-06-28 | Board Of Regents, The University Of Texas System | Liposomal curcumin for treatment of cancer |
| US7459147B2 (en) | 2003-06-30 | 2008-12-02 | L'oreal | Cosmetic composition comprising at least one hydrophilic organopolysiloxane, at least one hydrocarbon oil and at least one short hydrocarbon ester |
| US8784881B2 (en) * | 2004-03-05 | 2014-07-22 | Board Of Regents, The University Of Texas System | Liposomal curcumin for treatment of diseases |
| US20080103213A1 (en) * | 2004-03-05 | 2008-05-01 | Board Of Regents, The University Of Texas System | Liposomal curcumin for treatment of neurofibromatosis |
| EP3067047B1 (de) | 2005-12-08 | 2022-04-20 | Insmed Incorporated | Antiinfektive zusammensetzungen auf lipidbasis zur behandlung von lungeninfekten |
| WO2008137717A1 (en) | 2007-05-04 | 2008-11-13 | Transave, Inc. | Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof |
| US9114081B2 (en) | 2007-05-07 | 2015-08-25 | Insmed Incorporated | Methods of treating pulmonary disorders with liposomal amikacin formulations |
| US9333214B2 (en) | 2007-05-07 | 2016-05-10 | Insmed Incorporated | Method for treating pulmonary disorders with liposomal amikacin formulations |
| US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
| WO2009013115A2 (en) * | 2007-07-20 | 2009-01-29 | Basf Se | Vesicles comprising a transmembrane transport trigger system |
| EP2127640A1 (de) | 2008-05-27 | 2009-12-02 | Koninklijke Philips Electronics N.V. | Modifizierte azid-enthaltende Proteine |
| BRPI1010137A2 (pt) | 2009-06-24 | 2016-03-15 | Koninkl Philips Electronics Nv | método para transmitir dados a partir de um dispositivo de consumidor por uma linha de alimentação de tensão em ca para uma fonte de tensão em ca, método para uma comunicação em dois sentidos entre uma fonte de tensão em ca e um dispositivo do consumidor por uma linha de alimentação de tensão em ca, dispositivo de programação para programar um controlador em um driver eletrônico e driver eletrônico |
| WO2011097480A1 (en) | 2010-02-05 | 2011-08-11 | University Of Louisville Research Foundation, Inc. | Exosomal compositions and methods for the treatment of disease |
| PL2852391T3 (pl) | 2012-05-21 | 2022-04-11 | Insmed Incorporated | Układy do leczenia infekcji płuc |
| WO2014081300A1 (en) * | 2012-11-22 | 2014-05-30 | Tagworks Pharmaceuticals B.V. | Channel protein activatable liposomes |
| US10124066B2 (en) | 2012-11-29 | 2018-11-13 | Insmed Incorporated | Stabilized vancomycin formulations |
| CN105142614A (zh) | 2013-03-14 | 2015-12-09 | 迪克纳制药公司 | 用于配制阴离子试剂的方法 |
| LT3466432T (lt) | 2014-05-15 | 2020-12-28 | Insmed Incorporated | Būdai, skirti plaučių netuberkuliozinėms mikobakterinėms infekcijoms gydyti |
| EP3773505B1 (de) | 2018-03-30 | 2026-04-29 | Insmed Incorporated | Verfahren zur kontinuierlichen herstellung von liposomalen arzneimittelprodukten |
| JP7449275B2 (ja) | 2018-05-02 | 2024-03-13 | インスメッド インコーポレイテッド | リポソーム薬物製剤の製造方法 |
| EP3887826A1 (de) * | 2018-11-30 | 2021-10-06 | Corning Incorporated | System und verfahren zur analyse von extrazellulären vesikeln mit einem optischen biosensor |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4900556A (en) * | 1985-04-26 | 1990-02-13 | Massachusetts Institute Of Technology | System for delayed and pulsed release of biologically active substances |
| US5252263A (en) * | 1986-06-16 | 1993-10-12 | The Liposome Company, Inc. | Induction of asymmetry in vesicles |
| CA1335879C (en) * | 1987-07-27 | 1995-06-13 | Bruce Andrew Cornell | Receptor membranes |
| US5227470A (en) * | 1988-08-26 | 1993-07-13 | Canon Kabushiki Kaisha | Method for forming proteoliposome and method for forming giant proteoliposome |
| US5874316A (en) * | 1989-01-27 | 1999-02-23 | Australian Membrane Biotechnology Research Institute | Receptor membranes and ionophore gating |
| ES2102364T3 (es) * | 1989-01-27 | 1997-08-01 | Au Membrane & Biotech Res Inst | Membranas receptoras y control del paso a su traves por medio de ionoforos. |
| US5252348A (en) * | 1990-10-19 | 1993-10-12 | Univ. Of Florida Research Foundation, Inc. | Artificial viral envelopes |
| US5753258A (en) * | 1990-10-19 | 1998-05-19 | University Of Florida | Artificial viral envelopes |
| US5753261A (en) * | 1993-02-12 | 1998-05-19 | Access Pharmaceuticals, Inc. | Lipid-coated condensed-phase microparticle composition |
| US5820879A (en) * | 1993-02-12 | 1998-10-13 | Access Pharmaceuticals, Inc. | Method of delivering a lipid-coated condensed-phase microparticle composition |
| EP0712935B1 (de) * | 1994-11-18 | 2002-06-19 | Stichting Nederlands Instituut Voor Zuivelonderzoek | Verfahren zur Kontrolle der Genexpression in Milchsäurebakterien |
| AU742407B2 (en) * | 1997-07-15 | 2002-01-03 | Regents Of The University Of California, The | Isolated DNA encoding human calcium activated potassium channel |
| US6165732A (en) * | 1997-10-14 | 2000-12-26 | Washington University | Method for identifying apoptosis modulating compounds |
| GB9721901D0 (en) * | 1997-10-16 | 1997-12-17 | Univ Manchester | Particles |
-
2001
- 2001-06-21 EP EP01202401A patent/EP1269993A1/de not_active Withdrawn
-
2002
- 2002-06-21 AT AT02743969T patent/ATE453380T1/de not_active IP Right Cessation
- 2002-06-21 EP EP02743969A patent/EP1397123B1/de not_active Expired - Lifetime
- 2002-06-21 DK DK02743969.4T patent/DK1397123T3/da active
- 2002-06-21 CA CA002451148A patent/CA2451148A1/en not_active Abandoned
- 2002-06-21 DE DE60234921T patent/DE60234921D1/de not_active Expired - Lifetime
- 2002-06-21 WO PCT/NL2002/000412 patent/WO2003000233A2/en not_active Ceased
- 2002-10-24 US US10/281,048 patent/US20030118636A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003000233A2 (en) | 2003-01-03 |
| EP1397123B1 (de) | 2009-12-30 |
| DE60234921D1 (de) | 2010-02-11 |
| EP1269993A1 (de) | 2003-01-02 |
| DK1397123T3 (da) | 2010-05-03 |
| WO2003000233A3 (en) | 2003-10-16 |
| CA2451148A1 (en) | 2003-01-03 |
| US20030118636A1 (en) | 2003-06-26 |
| EP1397123A2 (de) | 2004-03-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |