ATE453393T1 - Verwendung von pyridylamiden als angiogenesehemmer - Google Patents
Verwendung von pyridylamiden als angiogenesehemmerInfo
- Publication number
- ATE453393T1 ATE453393T1 AT03744849T AT03744849T ATE453393T1 AT E453393 T1 ATE453393 T1 AT E453393T1 AT 03744849 T AT03744849 T AT 03744849T AT 03744849 T AT03744849 T AT 03744849T AT E453393 T1 ATE453393 T1 AT E453393T1
- Authority
- AT
- Austria
- Prior art keywords
- pyridylamide
- angiogenesis inhibitors
- inappropriate
- mammal
- chem
- Prior art date
Links
- 229940121369 angiogenesis inhibitor Drugs 0.000 title 1
- 239000004037 angiogenesis inhibitor Substances 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02006697A EP1348434A1 (de) | 2002-03-27 | 2002-03-27 | Verwendung von Pyridylamiden als Inhibitoren von Angiogenese |
| PCT/EP2003/003060 WO2003080054A1 (en) | 2002-03-27 | 2003-03-24 | Use of pyridyl amides as inhibitors of angiogenesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE453393T1 true ATE453393T1 (de) | 2010-01-15 |
Family
ID=27798796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03744849T ATE453393T1 (de) | 2002-03-27 | 2003-03-24 | Verwendung von pyridylamiden als angiogenesehemmer |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20060052419A1 (de) |
| EP (2) | EP1348434A1 (de) |
| JP (1) | JP4599062B2 (de) |
| AT (1) | ATE453393T1 (de) |
| AU (1) | AU2003215672A1 (de) |
| CY (1) | CY1109925T1 (de) |
| DE (1) | DE60330757D1 (de) |
| DK (1) | DK1487444T3 (de) |
| ES (1) | ES2337780T3 (de) |
| PT (1) | PT1487444E (de) |
| SI (1) | SI1487444T1 (de) |
| WO (1) | WO2003080054A1 (de) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7977049B2 (en) | 2002-08-09 | 2011-07-12 | President And Fellows Of Harvard College | Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms |
| ZA200608176B (en) * | 2004-03-15 | 2008-05-28 | Ptc Therapeutics Inc | Carboline derivatives useful in the inhibition of angiogenesis |
| US7767689B2 (en) | 2004-03-15 | 2010-08-03 | Ptc Therapeutics, Inc. | Carboline derivatives useful in the treatment of cancer |
| EP1987019B1 (de) * | 2006-02-17 | 2012-11-28 | F. Hoffmann-La Roche AG | Benzoylpiperidinderivate als 5ht2/d3-modulatoren |
| WO2008026018A1 (en) * | 2006-09-01 | 2008-03-06 | Topotarget Switzerland Sa | New method for the treatment of inflammatory diseases |
| EP2079693B1 (de) | 2006-10-31 | 2013-02-27 | F. Hoffmann-La Roche AG | Etherderivate als duale modulatoren der 5-ht2a- und d3-rezeptoren |
| EP2098231A1 (de) | 2008-03-05 | 2009-09-09 | Topotarget Switzerland SA | Verwendung von NAD Synthesis Hemmern zur Behandlung von ischämischen Reperfusionsschäden |
| MX2010014310A (es) | 2008-06-24 | 2011-02-15 | Topotarget As | Derivados de acido escuarico como inhibidores de la nicotinamida. |
| WO2010023307A1 (en) | 2008-08-29 | 2010-03-04 | Topotarget A/S | Novel urea and thiourea derivatives |
| WO2011121055A1 (en) | 2010-03-31 | 2011-10-06 | Topotarget A/S | Pyridinyl derivatives comprising a cyanoguanidine or squaric acid moiety |
| AU2011295725B2 (en) | 2010-09-03 | 2015-03-26 | Forma Tm, Llc. | Novel compounds and compositions for the inhibition of NAMPT |
| WO2012031196A1 (en) | 2010-09-03 | 2012-03-08 | Forma Therapeutics, Inc. | 4- { [ ( pyridin- 3 - yl -methyl) aminocarbonyl] amino} benzene - sulfone derivatives as nampt inhibitors for therapy of diseases such as cancer |
| US9676721B2 (en) | 2010-09-03 | 2017-06-13 | Forma Tm, Llc | Compounds and compositions for the inhibition of NAMPT |
| CA2817093A1 (en) | 2010-11-15 | 2012-05-24 | Abbvie Inc. | Nampt inhibitors |
| PE20140913A1 (es) | 2010-11-15 | 2014-08-22 | Abbvie Inc | Inhibidores de nampt y rock |
| AR082888A1 (es) | 2011-05-04 | 2013-01-16 | Forma Therapeutics Inc | Compuestos de piridina para la inhibicion de nampt |
| WO2012154194A1 (en) | 2011-05-09 | 2012-11-15 | Forma Tm, Llc | Piperidine derivatives and compositions for the inhibition of nicotinamide phosphoribosyltransferase (nampt) |
| CN104583194A (zh) | 2012-05-11 | 2015-04-29 | 艾伯维公司 | 作为nampt抑制剂的哒嗪和吡啶衍生物 |
| AR091022A1 (es) | 2012-05-11 | 2014-12-30 | Abbvie Inc | Inhibidores del nampt |
| US9334264B2 (en) | 2012-05-11 | 2016-05-10 | Abbvie Inc. | NAMPT inhibitors |
| WO2013170113A1 (en) | 2012-05-11 | 2013-11-14 | Abbvie Inc. | Nampt inhibitors |
| US9938258B2 (en) | 2012-11-29 | 2018-04-10 | Karyopharm Therapeutics Inc. | Substituted 2,3-dihydrobenzofuranyl compounds and uses thereof |
| US9227978B2 (en) | 2013-03-15 | 2016-01-05 | Araxes Pharma Llc | Covalent inhibitors of Kras G12C |
| EP2970121B1 (de) * | 2013-03-15 | 2017-12-13 | Araxes Pharma LLC | Kovalente inhibitoren von kras-g12c |
| CN108440515B (zh) | 2013-07-03 | 2022-05-03 | 卡尔约药物治疗公司 | 取代的苯并呋喃基和苯并噁唑基化合物及其用途 |
| US9994558B2 (en) | 2013-09-20 | 2018-06-12 | Karyopharm Therapeutics Inc. | Multicyclic compounds and methods of using same |
| JO3805B1 (ar) | 2013-10-10 | 2021-01-31 | Araxes Pharma Llc | مثبطات كراس جي12سي |
| ES2898765T3 (es) | 2015-04-10 | 2022-03-08 | Araxes Pharma Llc | Compuestos de quinazolina sustituidos y métodos de uso de los mismos |
| ES2856880T3 (es) | 2015-04-15 | 2021-09-28 | Araxes Pharma Llc | Inhibidores tricíclicos condensados de KRAS y métodos de uso de los mismos |
| US10144724B2 (en) | 2015-07-22 | 2018-12-04 | Araxes Pharma Llc | Substituted quinazoline compounds and methods of use thereof |
| EP3337797A1 (de) | 2015-08-18 | 2018-06-27 | Karyopharm Therapeutics, Inc. | (s,e) -3-(6-aminopyridin-3-yl ) -n-((5-(4-(3-fluor-3-methylpyrrolidin-1-carbonyl) ) phenyl) -7-(4-fluorphenyl) benzofuran-2-yl) methyl) acrylamid zur behandlung von krebs |
| EP3356353A1 (de) | 2015-09-28 | 2018-08-08 | Araxes Pharma LLC | Inhibitoren von kras-g12c-mutanten proteinen |
| US10975071B2 (en) | 2015-09-28 | 2021-04-13 | Araxes Pharma Llc | Inhibitors of KRAS G12C mutant proteins |
| WO2017058792A1 (en) | 2015-09-28 | 2017-04-06 | Araxes Pharma Llc | Inhibitors of kras g12c mutant proteins |
| EP3356347A1 (de) | 2015-09-28 | 2018-08-08 | Araxes Pharma LLC | Inhibitoren von kras-g12c-mutanten proteinen |
| US10730867B2 (en) | 2015-09-28 | 2020-08-04 | Araxes Pharma Llc | Inhibitors of KRAS G12C mutant proteins |
| US10689356B2 (en) | 2015-09-28 | 2020-06-23 | Araxes Pharma Llc | Inhibitors of KRAS G12C mutant proteins |
| US10647703B2 (en) | 2015-09-28 | 2020-05-12 | Araxes Pharma Llc | Inhibitors of KRAS G12C mutant proteins |
| US10414757B2 (en) | 2015-11-16 | 2019-09-17 | Araxes Pharma Llc | 2-substituted quinazoline compounds comprising a substituted heterocyclic group and methods of use thereof |
| US10858347B2 (en) | 2015-12-31 | 2020-12-08 | Karyopharm Therapeutics Inc. | Multicyclic compounds and uses thereof |
| US10646488B2 (en) | 2016-07-13 | 2020-05-12 | Araxes Pharma Llc | Conjugates of cereblon binding compounds and G12C mutant KRAS, HRAS or NRAS protein modulating compounds and methods of use thereof |
| WO2018064510A1 (en) | 2016-09-29 | 2018-04-05 | Araxes Pharma Llc | Inhibitors of kras g12c mutant proteins |
| US10377743B2 (en) | 2016-10-07 | 2019-08-13 | Araxes Pharma Llc | Inhibitors of RAS and methods of use thereof |
| WO2018086703A1 (en) | 2016-11-11 | 2018-05-17 | Bayer Pharma Aktiengesellschaft | Dihydropyridazinones substituted with phenylureas |
| WO2018140600A1 (en) | 2017-01-26 | 2018-08-02 | Araxes Pharma Llc | Fused hetero-hetero bicyclic compounds and methods of use thereof |
| US11136308B2 (en) | 2017-01-26 | 2021-10-05 | Araxes Pharma Llc | Substituted quinazoline and quinazolinone compounds and methods of use thereof |
| EP3573954A1 (de) | 2017-01-26 | 2019-12-04 | Araxes Pharma LLC | Fusionierte bicyclische benzoheteroaromatische verbindungen und verfahren zur verwendung davon |
| WO2018140599A1 (en) | 2017-01-26 | 2018-08-02 | Araxes Pharma Llc | Benzothiophene and benzothiazole compounds and methods of use thereof |
| EP3573971A1 (de) | 2017-01-26 | 2019-12-04 | Araxes Pharma LLC | 1-(3-(6-(3-hydroxynaphthalen-1-yl)benzofuran-2-yl)azetidin-1yl)prop-2-en-1-on-derivate und ähnliche verbindungen als kras-g12c-modulatoren zur behandlung von krebs |
| WO2018218069A1 (en) | 2017-05-25 | 2018-11-29 | Araxes Pharma Llc | Quinazoline derivatives as modulators of mutant kras, hras or nras |
| KR20200010306A (ko) | 2017-05-25 | 2020-01-30 | 아락세스 파마 엘엘씨 | Kras의 공유적 억제제 |
| CN110869357A (zh) | 2017-05-25 | 2020-03-06 | 亚瑞克西斯制药公司 | 化合物及其用于治疗癌症的使用方法 |
| KR20250107972A (ko) | 2018-05-04 | 2025-07-14 | 레미디 플랜, 인크. | 암 줄기 세포를 표적화하는 암 치료 |
| CA3107168A1 (en) | 2018-08-01 | 2020-02-06 | Araxes Pharma Llc | Heterocyclic spiro compounds and methods of use thereof for the treatment of cancer |
| CN109776494B (zh) * | 2018-12-25 | 2021-06-18 | 中国人民解放军第二军医大学 | 一种多靶点抗肿瘤活性的烟酰胺磷酸核糖转移酶氮芥类抑制剂及其制备与应用 |
| JP7352196B2 (ja) | 2019-01-16 | 2023-09-28 | 東レ株式会社 | ポリオレフィン多層微多孔膜 |
| WO2021013693A1 (en) | 2019-07-23 | 2021-01-28 | Bayer Pharma Aktiengesellschaft | Antibody drug conjugates (adcs) with nampt inhibitors |
| CA3217380A1 (en) | 2021-05-13 | 2022-11-17 | Yushma Bhurruth-Alcor | Nampt inhibitors and uses thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4224326A (en) * | 1978-09-21 | 1980-09-23 | Eli Lilly And Company | Immunosuppressive agents |
| US4778796A (en) * | 1985-07-19 | 1988-10-18 | Dainippon Pharmaceutical Co., Ltd. | ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same |
| DE19624668A1 (de) * | 1996-06-20 | 1998-02-19 | Klinge Co Chem Pharm Fab | Verwendung von Pyridylalkan-, Pyridylalken- bzw. Pyridylalkinsäureamiden |
| DE19624659A1 (de) * | 1996-06-20 | 1998-01-08 | Klinge Co Chem Pharm Fab | Neue Pyridylalken- und Pyridylalkinsäureamide |
| DE19624704A1 (de) * | 1996-06-20 | 1998-01-08 | Klinge Co Chem Pharm Fab | Neue Pyridylalkansäureamide |
| CA2260771A1 (en) * | 1996-07-17 | 1998-01-22 | The General Hospital Corporation | Method of inducing vasodilation and treating pulmonary hypertension using adenoviral-mediated transfer of the nitric oxide synthase gene |
| DE19756236A1 (de) * | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue piperazinylsubstituierte Pyridylalkan-, alken- und -alkincarbonsäureamide |
| DE19756212A1 (de) * | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue, mit einem cyclischen Imid substituierte Pyridylalkan-, alken- und -alkincarbonsäureamide |
| DE19756235A1 (de) * | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue piperidinylsubstituierte Pyridylalkan- alken- und -alkincarbonsäureamide |
| DE19756261A1 (de) * | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue arylsubstituierte Pyridylalkan-, alken- und alkincarbonsäureamide |
| DE19818044A1 (de) * | 1998-04-22 | 1999-10-28 | Klinge Co Chem Pharm Fab | Verwendung von Vitamin-PP-Verbindungen |
-
2002
- 2002-03-27 EP EP02006697A patent/EP1348434A1/de not_active Withdrawn
-
2003
- 2003-03-24 SI SI200331755T patent/SI1487444T1/sl unknown
- 2003-03-24 PT PT03744849T patent/PT1487444E/pt unknown
- 2003-03-24 AU AU2003215672A patent/AU2003215672A1/en not_active Abandoned
- 2003-03-24 DK DK03744849.5T patent/DK1487444T3/da active
- 2003-03-24 DE DE60330757T patent/DE60330757D1/de not_active Expired - Lifetime
- 2003-03-24 ES ES03744849T patent/ES2337780T3/es not_active Expired - Lifetime
- 2003-03-24 US US10/509,362 patent/US20060052419A1/en not_active Abandoned
- 2003-03-24 EP EP03744849A patent/EP1487444B9/de not_active Expired - Lifetime
- 2003-03-24 JP JP2003577882A patent/JP4599062B2/ja not_active Expired - Fee Related
- 2003-03-24 AT AT03744849T patent/ATE453393T1/de active
- 2003-03-24 WO PCT/EP2003/003060 patent/WO2003080054A1/en not_active Ceased
-
2010
- 2010-03-22 CY CY20101100264T patent/CY1109925T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1487444B1 (de) | 2009-12-30 |
| EP1487444B9 (de) | 2010-07-21 |
| EP1487444A1 (de) | 2004-12-22 |
| AU2003215672A1 (en) | 2003-10-08 |
| DE60330757D1 (de) | 2010-02-11 |
| CY1109925T1 (el) | 2014-09-10 |
| EP1348434A1 (de) | 2003-10-01 |
| ES2337780T3 (es) | 2010-04-29 |
| WO2003080054A1 (en) | 2003-10-02 |
| SI1487444T1 (sl) | 2010-04-30 |
| JP2005528361A (ja) | 2005-09-22 |
| DK1487444T3 (da) | 2010-04-12 |
| JP4599062B2 (ja) | 2010-12-15 |
| PT1487444E (pt) | 2010-02-11 |
| US20060052419A1 (en) | 2006-03-09 |
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