ATE453416T1 - Medizinischer stent mit einer kombination aus melatonin und paclitaxel - Google Patents
Medizinischer stent mit einer kombination aus melatonin und paclitaxelInfo
- Publication number
- ATE453416T1 ATE453416T1 AT07802809T AT07802809T ATE453416T1 AT E453416 T1 ATE453416 T1 AT E453416T1 AT 07802809 T AT07802809 T AT 07802809T AT 07802809 T AT07802809 T AT 07802809T AT E453416 T1 ATE453416 T1 AT E453416T1
- Authority
- AT
- Austria
- Prior art keywords
- melatonin
- paclitaxel
- combination
- medical stent
- stent
- Prior art date
Links
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 title abstract 2
- 229930012538 Paclitaxel Natural products 0.000 title abstract 2
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003987 melatonin Drugs 0.000 title abstract 2
- 229960001592 paclitaxel Drugs 0.000 title abstract 2
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title abstract 2
- 208000031481 Pathologic Constriction Diseases 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 208000037803 restenosis Diseases 0.000 abstract 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 abstract 1
- 208000037804 stenosis Diseases 0.000 abstract 1
- 230000036262 stenosis Effects 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Surgery (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2006008286 | 2006-08-23 | ||
| PCT/EP2007/058743 WO2008023038A1 (en) | 2006-08-23 | 2007-08-22 | Medical stent provided with a combination of melatonin and paclitaxel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE453416T1 true ATE453416T1 (de) | 2010-01-15 |
Family
ID=37866137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07802809T ATE453416T1 (de) | 2006-08-23 | 2007-08-22 | Medizinischer stent mit einer kombination aus melatonin und paclitaxel |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20090258053A1 (de) |
| EP (1) | EP2056897B1 (de) |
| JP (1) | JP5385785B2 (de) |
| AT (1) | ATE453416T1 (de) |
| CA (1) | CA2660900A1 (de) |
| DE (1) | DE602007004124D1 (de) |
| WO (1) | WO2008023038A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070053845A1 (en) * | 2004-03-02 | 2007-03-08 | Shiladitya Sengupta | Nanocell drug delivery system |
| AU2005219413A1 (en) * | 2004-03-02 | 2005-09-15 | Massachusetts Institute Of Technology | Nanocell drug delivery system |
| US9265633B2 (en) | 2009-05-20 | 2016-02-23 | 480 Biomedical, Inc. | Drug-eluting medical implants |
| EP2532372B1 (de) * | 2010-02-02 | 2015-02-25 | Terumo Kabushiki Kaisha | Biologisch abbaubarer stent |
| US20150073388A1 (en) * | 2013-09-09 | 2015-03-12 | Maria Palasis | Drug delivery systems and related methods |
| US11839698B2 (en) * | 2014-03-13 | 2023-12-12 | W. L. Gore & Associates, Inc. | Drug composition and coating |
| US10143779B2 (en) * | 2014-05-16 | 2018-12-04 | Terumo Kabushiki Kaisha | Method of inhibiting thickening of vascular intima |
| DE102015000662B3 (de) | 2015-01-23 | 2016-06-09 | Jenoptik Laser Gmbh | Laseranordnung mit Hilfsring |
| US10232082B2 (en) | 2015-06-29 | 2019-03-19 | 480 Biomedical, Inc. | Implantable scaffolds for treatment of sinusitis |
| CN108135688B (zh) | 2015-06-29 | 2021-06-04 | 莱拉医药公司 | 用于治疗鼻窦炎的可植入支架 |
| US12564659B2 (en) | 2017-04-20 | 2026-03-03 | Lyra Therapeutics, Inc. | Implantable scaffolds for treatment of sinusitis |
| CN112048081B (zh) * | 2020-08-19 | 2022-10-28 | 浙江工业大学 | 一种高强度全降解型木质素基高吸水性树脂及其制备方法 |
| US11312684B1 (en) | 2021-02-10 | 2022-04-26 | Eleusis Therapeutics Us, Inc. | Pharmaceutically acceptable salts of psilocin and uses thereof |
| WO2025099444A1 (en) * | 2023-11-09 | 2025-05-15 | Beckley Psytech Limited | N-Acetylserotonin (NAS) Analogues |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6258121B1 (en) * | 1999-07-02 | 2001-07-10 | Scimed Life Systems, Inc. | Stent coating |
| WO2001049268A1 (en) * | 2000-01-05 | 2001-07-12 | Imarx Therapeutics, Inc. | Pharmaceutical formulations for the delivery of drugs having low aqueous solubility |
| DE60238422D1 (de) * | 2001-09-24 | 2011-01-05 | Boston Scient Ltd | Optimierte dosierung bei paclitaxelhaltigen stents |
| KR20140027554A (ko) * | 2002-12-09 | 2014-03-06 | 아브락시스 바이오사이언스, 엘엘씨 | 약리학적 물질의 조성물 및 그 전달방법 |
| CA2536961A1 (en) * | 2003-08-14 | 2005-02-24 | Blue Medical Devices B.V. | Endoluminal prosthesis comprising a therapeutic agent |
| US7220816B2 (en) * | 2003-12-16 | 2007-05-22 | Advanced Cardiovascular Systems, Inc. | Biologically absorbable coatings for implantable devices based on poly(ester amides) and methods for fabricating the same |
| US20060083768A1 (en) * | 2004-09-28 | 2006-04-20 | Atrium Medical Corporation | Method of thickening a coating using a drug |
| US8609123B2 (en) * | 2004-11-29 | 2013-12-17 | Advanced Cardiovascular Systems, Inc. | Derivatized poly(ester amide) as a biobeneficial coating |
-
2007
- 2007-08-22 DE DE602007004124T patent/DE602007004124D1/de active Active
- 2007-08-22 WO PCT/EP2007/058743 patent/WO2008023038A1/en not_active Ceased
- 2007-08-22 AT AT07802809T patent/ATE453416T1/de not_active IP Right Cessation
- 2007-08-22 US US12/438,311 patent/US20090258053A1/en not_active Abandoned
- 2007-08-22 EP EP07802809A patent/EP2056897B1/de not_active Ceased
- 2007-08-22 JP JP2009525069A patent/JP5385785B2/ja not_active Expired - Fee Related
- 2007-08-22 CA CA002660900A patent/CA2660900A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2056897A1 (de) | 2009-05-13 |
| WO2008023038A1 (en) | 2008-02-28 |
| CA2660900A1 (en) | 2008-02-28 |
| JP2010501229A (ja) | 2010-01-21 |
| JP5385785B2 (ja) | 2014-01-08 |
| DE602007004124D1 (de) | 2010-02-11 |
| EP2056897B1 (de) | 2009-12-30 |
| US20090258053A1 (en) | 2009-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |