ATE455773T1 - Zur behandlung von schmerzen geeignete therapeutische mittel - Google Patents

Zur behandlung von schmerzen geeignete therapeutische mittel

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Publication number
ATE455773T1
ATE455773T1 AT04779721T AT04779721T ATE455773T1 AT E455773 T1 ATE455773 T1 AT E455773T1 AT 04779721 T AT04779721 T AT 04779721T AT 04779721 T AT04779721 T AT 04779721T AT E455773 T1 ATE455773 T1 AT E455773T1
Authority
AT
Austria
Prior art keywords
substituted pyridyl
pyridyl compound
animal
effective amount
disclosed
Prior art date
Application number
AT04779721T
Other languages
English (en)
Inventor
Donald Kyle
Qun Sun
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Application granted granted Critical
Publication of ATE455773T1 publication Critical patent/ATE455773T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3

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AT04779721T 2003-08-01 2004-07-30 Zur behandlung von schmerzen geeignete therapeutische mittel ATE455773T1 (de)

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PT1942106E (pt) 2011-12-22
ES2340168T3 (es) 2010-05-31
DE602004025244D1 (de) 2010-03-11
CY1112129T1 (el) 2015-11-04
EP1942106B1 (de) 2011-09-14
AU2004261666B2 (en) 2009-06-18
DK1942106T3 (da) 2011-12-19
JP2007501240A (ja) 2007-01-25
CN1832935A (zh) 2006-09-13
HRP20100229T1 (hr) 2010-05-31
EP1648880A1 (de) 2006-04-26
HRP20110891T1 (hr) 2011-12-31
SI1648880T1 (sl) 2010-05-31
WO2005012287A1 (en) 2005-02-10
US8030310B2 (en) 2011-10-04
US7696208B2 (en) 2010-04-13
SI1942106T1 (sl) 2012-01-31
ATE524455T1 (de) 2011-09-15
US20060258669A1 (en) 2006-11-16
DK1648880T3 (da) 2010-05-10
EP1942106A1 (de) 2008-07-09
MXPA06001331A (es) 2006-05-04
EP1648880B1 (de) 2010-01-20
HK1120799A1 (en) 2009-04-09
EP2275420A1 (de) 2011-01-19
PL1648880T3 (pl) 2010-06-30
ES2374017T3 (es) 2012-02-13
CY1110004T1 (el) 2015-01-14
US20100240675A1 (en) 2010-09-23
PT1648880E (pt) 2010-04-26
CA2534088C (en) 2011-01-11
CA2534088A1 (en) 2005-02-10
HK1093489A1 (en) 2007-03-02
PL1942106T3 (pl) 2012-02-29
AU2004261666A1 (en) 2005-02-10
JP5148110B2 (ja) 2013-02-20

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