ATE455785T1 - Neue pyrazolderivate und diese enthaltende mittel gegen diabetes - Google Patents

Neue pyrazolderivate und diese enthaltende mittel gegen diabetes

Info

Publication number: ATE455785T1
Authority: AT; Austria
Prior art keywords: group; lower alkyl; perfluoro; alkyl group; pyrazole derivatives
Prior art date: 2000-11-02

Application number

AT01978978T

Other languages

English (en)

Inventor

K Ohsumi

T Umemura

H Matsueda

T Hatanaka

A Onuki

K Maezono

Yoko Kageyama

N Kondo

Original Assignee

Ajinomoto Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-02

Filing date

2001-10-31

Publication date

2010-02-15

2001-10-31 Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk

2010-02-15 Application granted granted Critical

2010-02-15 Publication of ATE455785T1 publication Critical patent/ATE455785T1/de

Links

206010012601 diabetes mellitus Diseases 0.000 title abstract 2
WTKZEGDFNFYCGP-UHFFFAOYSA-N Pyrazole Chemical class C=1C=NNC=1 WTKZEGDFNFYCGP-UHFFFAOYSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 6
-1 perfluoro Chemical group 0.000 abstract 5
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000004414 alkyl thio group Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000002252 acyl group Chemical group 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003282 alkyl amino group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003217 pyrazoles Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Diabetes (AREA)
Biochemistry (AREA)
Epidemiology (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Genetics & Genomics (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

AT01978978T 2000-11-02 2001-10-31 Neue pyrazolderivate und diese enthaltende mittel gegen diabetes ATE455785T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP2000335851		2000-11-02
JP2001131264		2001-04-27
PCT/JP2001/009555 WO2002036602A1 (en)	2000-11-02	2001-10-31	Novel pyrazole derivatives and diabetes remedies containing the same

Publications (1)

Publication Number	Publication Date
ATE455785T1 true ATE455785T1 (de)	2010-02-15

Family

ID=26603344

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01978978T ATE455785T1 (de)	2000-11-02	2001-10-31	Neue pyrazolderivate und diese enthaltende mittel gegen diabetes

Country Status (8)

Country	Link
US (6)	US6815428B2 (de)
EP (2)	EP1338603B1 (de)
JP (1)	JP3915116B2 (de)
AT (1)	ATE455785T1 (de)
AU (1)	AU2002210990A1 (de)
DE (1)	DE60141156D1 (de)
ES (1)	ES2337127T3 (de)
WO (1)	WO2002036602A1 (de)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1020944C (zh)	1990-01-30	1993-05-26	阿图尔-费希尔股份公司费希尔厂	紧固件
ATE264337T1 (de) *	1999-08-31	2004-04-15	Kissei Pharmaceutical	Glucopyranosyloxypyrazol-derivate, diese enthaltende arzneimittel und zwischenprodukte zu deren herstellung
JP4591781B2 (ja) *	2000-11-02	2010-12-01	味の素株式会社	新規ピラゾール誘導体及びそれらを含有する糖尿病治療薬
ATE455785T1 (de) *	2000-11-02	2010-02-15	Ajinomoto Kk	Neue pyrazolderivate und diese enthaltende mittel gegen diabetes
PL209375B1 (pl)	2000-12-28	2011-08-31	Kissei Pharmaceutical	Pochodne glukopiranozyloksypirazolu, kompozycja farmaceutyczna zawierająca takie pochodne i zastosowanie tych pochodnych do wytwarzania kompozycji farmaceutycznej
CA2438593C (en) *	2001-02-26	2010-09-21	Kissei Pharmaceutical Co., Ltd.	Glucopyranosyloxypyrazole derivatives and medicinal use thereof
CA2438595C (en)	2001-02-27	2011-08-09	Kissei Pharmaceutical Co., Ltd.	Glucopyranosyloxypyrazole derivatives and medicinal use thereof
JP4292570B2 (ja) *	2001-04-27	2009-07-08	味の素株式会社	Ｎ−置換ピラゾール−ｏ−グリコシド誘導体及びそれらを含有する糖尿病治療薬
US7217697B2 (en)	2001-05-30	2007-05-15	Kissei Pharmaceutical Co., Ltd.	Glucopyranosyloxypyrazole derivative medicinal composition containing the same medicinal use thereof and intermediate therefor
US20030087843A1 (en) *	2001-09-05	2003-05-08	Washburn William N.	O-pyrazole glucoside SGLT2 inhibitors and method of use
US7956041B2 (en)	2002-04-26	2011-06-07	Ajinomoto Co., Inc.	Prophylactic and therapeutic agent of diabetes mellitus
CA2484306A1 (en) *	2002-04-26	2003-11-06	Katsumi Maezono	Prophylactic and therapeutic agent of diabetes mellitus
UA79804C2 (en) *	2002-07-03	2007-07-25	Janssen Pharmaceutica Nv	Cck-1 receptor modulators
PL213095B1 (pl) *	2002-08-08	2013-01-31	Kissei Pharmaceutical	Pochodna pirazolu, kompozycja farmaceutyczna, srodek do leczenia lub hamowania choroby i zastosowanie pochodnej pirazolu
ZA200501094B (en) *	2002-08-08	2006-10-25	Kissei Pharmaceutical	Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof
RU2322449C2 (ru) *	2002-08-09	2008-04-20	Тайсо Фармасьютикал Ко., Лтд.	ПРОИЗВОДНЫЕ АРИЛ 5-ТИО-β-D-ГЛЮКОПИРАНОЗИДА И ТЕРАПЕВТИЧЕСКИЕ СРЕДСТВА ПРИ ДИАБЕТЕ, СОДЕРЖАЩИЕ ИХ
ZA200501549B (en) *	2002-08-23	2006-07-26	Kissei Pharmaceutical	Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof and intermediate for the production thereof
JP2004137245A (ja) *	2002-08-23	2004-05-13	Kissei Pharmaceut Co Ltd	ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体
JP4606876B2 (ja) *	2002-08-27	2011-01-05	キッセイ薬品工業株式会社	ピラゾール誘導体、それを含有する医薬組成物及びその医薬用途
CA2500873C (en) *	2002-10-04	2012-01-17	Kissei Pharmaceutical Co., Ltd.	Pyrazole derivative, medicinal composition containing the same, medicinal use thereof and intermediate in producing the same
KR20050089156A (ko) *	2002-12-04	2005-09-07	깃세이 야쿠힌 고교 가부시키가이샤	고혈당증에 기인하는 질환의 예방 또는 치료제
DE10258008B4 (de)	2002-12-12	2006-02-02	Sanofi-Aventis Deutschland Gmbh	Heterocyclische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
DE10258007B4 (de)	2002-12-12	2006-02-09	Sanofi-Aventis Deutschland Gmbh	Aromatische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
AU2003289440A1 (en) *	2002-12-25	2004-07-22	Kissei Pharmaceutical Co., Ltd.	Nitrogen-containing heterocycic derivatives, medicinal compositions containing the same and medicinal use thereof
CN1761676A (zh)	2003-04-01	2006-04-19	大正制药株式会社	杂芳基5－硫代－β－D－吡喃葡糖苷衍生物及含有该衍生物的糖尿病治疗药
WO2004089966A1 (ja) *	2003-04-01	2004-10-21	Taisho Pharmaceutical Co., Ltd.	選択的なヘテロアリール５－チオ－β－Ｄ－アルドヘキソピラノシドの製造法
BRPI0409447A (pt) *	2003-04-14	2006-04-18	Inst For Pharm Discovery Inc	ácidos fenilalcanóicos substituìdos
EP1637539B1 (de) *	2003-06-20	2012-01-18	Kissei Pharmaceutical Co., Ltd.	Pyrazolderivat, arzneimittelzusammensetzung, die dieses enthält, und zwischenprodukt für dessen herstellung
LT2896397T (lt)	2003-08-01	2017-11-27	Mitsubishi Tanabe Pharma Corporation	Nauji junginiai, turintys inhibitorinį aktyvumą prieš nuo natrio priklausomą gliukozės transporterį
US8785403B2 (en)	2003-08-01	2014-07-22	Mitsubishi Tanabe Pharma Corporation	Glucopyranoside compound
EP1660509B1 (de) *	2003-08-26	2009-02-04	Boehringer Ingelheim International GmbH	Glucopyranosyloxy-pyrazole, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung
US7375090B2 (en)	2003-08-26	2008-05-20	Boehringer Ingelheim International Gmbh	Glucopyranosyloxy-pyrazoles, pharmaceutical compositions containing these compounds, the use thereof and processed for the preparation thereof
DE102004028241B4 (de) *	2004-06-11	2007-09-13	Sanofi-Aventis Deutschland Gmbh	Neue Fluorglykosidderivate von Pyrazolen, diese Verbindungen enthaltende Arzneimittel und Herstellung dieser Arzneimittel
TW200606129A (en)	2004-07-26	2006-02-16	Chugai Pharmaceutical Co Ltd	Novel cyclohexane derivative, its prodrug, its salt and diabetic therapeutic agent containing the same
TW200630327A (en) *	2004-10-28	2006-09-01	Inst For Pharm Discovery Inc	Substituted phenylalkanoic acids
EP1813611B1 (de) *	2004-11-18	2014-10-01	Kissei Pharmaceutical Co., Ltd.	1-substituierte 3-beta-d-glycopyranosylierte stickstoffhaltige heterocyclische verbindungen und medikamente, die diese enthalten
TW200637869A (en)	2005-01-28	2006-11-01	Chugai Pharmaceutical Co Ltd	The spiroketal derivatives and the use as therapeutical agent for diabetes of the same
WO2006098413A1 (ja) *	2005-03-17	2006-09-21	Kissei Pharmaceutical Co., Ltd.	グルコピラノシルオキシピラゾール誘導体の製造方法
JP4888840B2 (ja) *	2005-07-22	2012-02-29	味の素株式会社	ピラゾール−ｏ−グリコシド誘導体の調製方法及び前記方法の新規中間体
UY29694A1 (es) *	2005-07-28	2007-02-28	Boehringer Ingelheim Int	Metodos para prevenir y tratar trastornos metabolicos y nuevos derivados de pirazol-o-glucosido
UY30082A1 (es) *	2006-01-11	2007-08-31	Boehringer Ingelheim Int	Forma cristalina de 1-(1-metiletil)-4`-((2-fluoro-4-metoxifenil)metil)-5`- metil-1h-pirazol-3`-o-b-d-glucopiranosido, un metodo para su preparacion y el uso de la misma para preparar medicamentos
US7834050B2 (en)	2006-03-29	2010-11-16	Duke University	Small molecule insulin mimetics absent quinones
PE20110235A1 (es)	2006-05-04	2011-04-14	Boehringer Ingelheim Int	Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
DE102006028862A1 (de)	2006-06-23	2007-12-27	Merck Patent Gmbh	3-Amino-imidazo[1,2-a]pyridinderivate
US20080020987A1 (en) *	2006-07-20	2008-01-24	Waldemar Pfrengle	Processes for preparing pyrazole-O-glycoside derivatives and novel intermediates of said processes
UY30730A1 (es)	2006-12-04	2008-07-03	Mitsubishi Tanabe Pharma Corp	Forma cristalina del hemihidrato de 1-(b (beta)-d-glucopiranosil) -4-metil-3-[5-(4-fluorofenil) -2-tienilmetil]benceno
ATE528300T1 (de)	2006-12-06	2011-10-15	Glaxosmithkline Llc	Bizyklische verbindungen und ihre verwendung als antidiabetika
DE102007008420A1 (de)	2007-02-21	2008-08-28	Merck Patent Gmbh	Benzimidazolderivate
MX2010002695A (es)	2007-09-10	2010-04-01	Janssen Pharmaceutica Nv	Proceso para la preparacion de compuestos utiles como inhibidores de transportador de glucosa dependiente de sodio (sglt).
DE102007048716A1 (de)	2007-10-11	2009-04-23	Merck Patent Gmbh	Imidazo[1,2-a]pyrimidinderivate
CL2008003653A1 (es)	2008-01-17	2010-03-05	Mitsubishi Tanabe Pharma Corp	Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica.
DE102008017590A1 (de)	2008-04-07	2009-10-08	Merck Patent Gmbh	Glucopyranosidderivate
US8791077B2 (en)	2008-05-22	2014-07-29	Astrazeneca Ab	Method for treating hyperuricemia employing an SGLT2 inhibitor and composition containing same
MY155418A (en) *	2008-08-28	2015-10-15	Pfizer	Dioxa-bicyclo[3.2.1]octane-2,3,4-triol derivatives
US9056850B2 (en)	2008-10-17	2015-06-16	Janssen Pharmaceutica N.V.	Process for the preparation of compounds useful as inhibitors of SGLT
US20110009347A1 (en)	2009-07-08	2011-01-13	Yin Liang	Combination therapy for the treatment of diabetes
KR101532412B1 (ko)	2009-07-10	2015-06-29	얀센 파마슈티카 엔.브이.	1-(β-Ｄ-글루코피라노실)-4-메틸-3-(5-(4-플루오로페닐)-2-티에닐메틸) 벤젠의 결정화 방법
EP2298782A1 (de) *	2009-08-26	2011-03-23	Sanofi-Aventis	Verfahren zur Herstellung von Pyrazol-glykosid-Derivate
SI2488515T1 (sl)	2009-10-14	2017-04-26	Janssen Pharmaceutica Nv	Postopek za pripravo spojin, ki so uporabne kot inhibitorji SGLT2
EA021983B1 (ru)	2009-11-02	2015-10-30	Пфайзер Инк.	Производные диоксабицикло[3.2.1]октан-2,3,4-триола
WO2011070592A2 (en)	2009-12-09	2011-06-16	Panacea Biotec Ltd.	Novel sugar derivatives
WO2011107494A1 (de)	2010-03-03	2011-09-09	Sanofi	Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
TWI599360B (zh)	2010-05-11	2017-09-21	健生藥品公司	醫藥調配物
RS55056B1 (sr)	2011-04-13	2016-12-30	Janssen Pharmaceutica Nv	Proces za pripremu jedinjenja koja su korisna kao inhibitori sglt2
TWI542596B (zh)	2011-05-09	2016-07-21	健生藥品公司	（２ｓ,３ｒ,４ｒ,５ｓ,６ｒ）－２－（３－（（５－（４－氟苯基）噻吩－２－基）甲基）－４－甲基苯基）－６－（羥甲基）四氫－２ｈ－哌喃－３,４,５－三醇之ｌ－脯胺酸及檸檬酸共晶體
EP2774619B1 (de)	2013-03-04	2016-05-18	BioActive Food GmbH	Zusammensetzung zur Behandlung von hyperglykämischen Erkrankungen
EP2944311A1 (de)	2014-05-16	2015-11-18	BioActive Food GmbH	Kombination von biologisch aktiven Substanzen zur Behandlung von hyperglykämischen Erkrankungen
US20170071970A1 (en)	2015-09-15	2017-03-16	Janssen Pharmaceutica Nv	Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders
EP3583222A4 (de)	2017-02-17	2021-01-13	Hyasynth Biologicals Inc.	Verfahren und zelllinie zur herstellung von phytocannabinoiden und phytocannabinoid-analoga in hefe
BR112021000139A2 (pt)	2018-07-19	2021-04-06	Astrazeneca Ab	Métodos de tratamento da hfpef empregando dapagliflozina e composições compreendendo a mesma
WO2020039394A1 (en)	2018-08-24	2020-02-27	Novartis Ag	New drug combinations
AU2021202643B2 (en)	2020-07-27	2023-02-02	Astrazeneca Ab	Methods of treating chronic kidney disease with dapagliflozin
TW202220672A (zh)	2020-07-27	2022-06-01	瑞典商阿斯特捷利康公司	用達格列淨治療慢性腎臟病之方法
EP4315350A1 (de)	2021-04-01	2024-02-07	AstraZeneca UK Limited	Systeme und verfahren zur verwaltung von prädiabetes mit einer pharmazeutischen gliflozin-natrium-glucose-cotransport-2-inhibitorzusammensetzung
US20250108065A1 (en)	2022-01-26	2025-04-03	Astrazeneca Ab	Methods of treating prediabetes or reducing the risk of developing type 2 diabetes with dapagliflozin
WO2025125513A1 (en)	2023-12-15	2025-06-19	AstraZeneca Ireland Limited	Sglt2 inhibitors and baxdrostat for treating chronic kidney disease and hypertension

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5274111A (en) *	1992-04-07	1993-12-28	American Home Products Corporation	Trifluoromethyl substituted 1H-pyrazoles and derivatives thereof
US5264451A (en) *	1992-04-07	1993-11-23	American Home Products Corporation	Process for treating hyperglycemia using trifluoromethyl substituted 3H-pyrazol-3-ones
EP0850946A1 (de)	1996-12-24	1998-07-01	Ciba SC Holding AG	Cyclische Phosphinsäurederivate als Stabilisatoren
AU719726B2 (en)	1996-12-26	2000-05-18	Tanabe Seiyaku Co., Ltd.	Propiophenone derivatives and process for preparing the same
ATE264337T1 (de)	1999-08-31	2004-04-15	Kissei Pharmaceutical	Glucopyranosyloxypyrazol-derivate, diese enthaltende arzneimittel und zwischenprodukte zu deren herstellung
ATE455785T1 (de) *	2000-11-02	2010-02-15	Ajinomoto Kk	Neue pyrazolderivate und diese enthaltende mittel gegen diabetes
PL209375B1 (pl)	2000-12-28	2011-08-31	Kissei Pharmaceutical	Pochodne glukopiranozyloksypirazolu, kompozycja farmaceutyczna zawierająca takie pochodne i zastosowanie tych pochodnych do wytwarzania kompozycji farmaceutycznej
CA2438593C (en)	2001-02-26	2010-09-21	Kissei Pharmaceutical Co., Ltd.	Glucopyranosyloxypyrazole derivatives and medicinal use thereof
JP4292570B2 (ja)	2001-04-27	2009-07-08	味の素株式会社	Ｎ−置換ピラゾール−ｏ−グリコシド誘導体及びそれらを含有する糖尿病治療薬
JP4115105B2 (ja)	2001-07-02	2008-07-09	協和醗酵工業株式会社	ピラゾール誘導体
US7956041B2 (en) *	2002-04-26	2011-06-07	Ajinomoto Co., Inc.	Prophylactic and therapeutic agent of diabetes mellitus

2001
- 2001-10-31 AT AT01978978T patent/ATE455785T1/de not_active IP Right Cessation
- 2001-10-31 WO PCT/JP2001/009555 patent/WO2002036602A1/ja not_active Ceased
- 2001-10-31 DE DE60141156T patent/DE60141156D1/de not_active Expired - Lifetime
- 2001-10-31 JP JP2002539360A patent/JP3915116B2/ja not_active Expired - Fee Related
- 2001-10-31 AU AU2002210990A patent/AU2002210990A1/en not_active Abandoned
- 2001-10-31 ES ES01978978T patent/ES2337127T3/es not_active Expired - Lifetime
- 2001-10-31 EP EP01978978A patent/EP1338603B1/de not_active Expired - Lifetime
- 2001-10-31 EP EP09013281A patent/EP2163555A1/de not_active Withdrawn
2003
- 2003-05-02 US US10/427,959 patent/US6815428B2/en not_active Expired - Fee Related
2004
- 2004-09-09 US US10/936,535 patent/US7015201B2/en not_active Expired - Fee Related
2005
- 2005-10-24 US US11/255,937 patent/US7247616B2/en not_active Expired - Fee Related
2006
- 2006-12-05 US US11/567,039 patent/US7256209B2/en not_active Expired - Fee Related
2007
- 2007-07-06 US US11/774,102 patent/US7645787B2/en not_active Expired - Fee Related
2009
- 2009-11-19 US US12/621,626 patent/US20100063124A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1338603B1 (de)	2010-01-20
AU2002210990A1 (en)	2002-05-15
EP1338603A4 (de)	2007-03-28
US20060058244A1 (en)	2006-03-16
US20040006025A1 (en)	2004-01-08
US20100063124A1 (en)	2010-03-11
US6815428B2 (en)	2004-11-09
JPWO2002036602A1 (ja)	2004-03-11
US20050043249A1 (en)	2005-02-24
US7247616B2 (en)	2007-07-24
US7015201B2 (en)	2006-03-21
ES2337127T3 (es)	2010-04-21
JP3915116B2 (ja)	2007-05-16
US20070270479A1 (en)	2007-11-22
US7645787B2 (en)	2010-01-12
DE60141156D1 (de)	2010-03-11
US7256209B2 (en)	2007-08-14
WO2002036602A1 (en)	2002-05-10
EP1338603A1 (de)	2003-08-27
US20070099979A1 (en)	2007-05-03
EP2163555A1 (de)	2010-03-17

Legal Events

Date	Code	Title	Description
2010-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE455785T1 (de)	2010-02-15	Neue pyrazolderivate und diese enthaltende mittel gegen diabetes
DE69705480D1 (de)	2001-08-09	Verwendung von Oestrogenagonisten und -antagonisten zur Herstellung eines Medikaments zur Behandlung von Atherosklerose, unabhängig von Lipidsenkung
AU2284099A (en)	1999-10-18	Poly-aminoacid derivatives and their use in compositions for treating keratinousfibres
ATE327230T1 (de)	2006-06-15	Piperidinverbindungen und diese enthaltenden medikamente
ATE275134T1 (de)	2004-09-15	4-oxo-1,4-dihydro-3-chinolincarboxamide als antivirale mittel
HUP9802304A2 (hu)	1999-01-28	Piridazin-3-on-származékok, intermedierjeik, alkalmazásuk, a vegyületeket hatóanyagként tartalmazó herbicid készítmények
ES2163478T3 (es)	2002-02-01	Procedimiento de preparacion de composiciones cosmeticas o farmaceuticas que contienen liposomas.
ATE191473T1 (de)	2000-04-15	2,3,5-trimethyl-hydroxyanilid-derivative, ihre herstellung und ihre theraoeutische verwendung
ATE205072T1 (de)	2001-09-15	Kosmetische zusammensetzung enthaltend eine indigotyp-verbindung
ID23053A (id)	2000-01-20	Karboksamida yang digunakan sebagai agonis 5-ht <if>
BG105919A (en)	2002-06-28	Erythromycin derivatives
DK0947504T3 (da)	2003-11-24	16-en-vitamin D-derivater
DE60207796D1 (de)	2006-01-12	Electrochrome Lösung, enthaltend eine Hydrazonverbindung und mit dieser hergestellte Vorrichtung
DE60016384D1 (de)	2005-01-05	Chondrogonese promotoren und indolin-2-on derivate
BG101442A (en)	1998-03-31	New taxoids, their preparation and pharmaceutical compositions containing them
ATE356112T1 (de)	2007-03-15	Thio-derivate als würzende bestandteile
ATE195517T1 (de)	2000-09-15	Chinolinonderivate und diese enthaltende antiallergische zusammensetzungen
EP1285647A3 (de)	2003-07-02	Kosmetisches Haarpflegemittel enthaltend ein Guanidinderivat und ein N-alpha-Acylarginin
PT1206448E (pt)	2004-08-31	Novos analogos de vitamina d
TR200102205T2 (tr)	2002-01-21	Anti-konvülsan türevlerinin bulimia nevruza tedavisinde kullanılmaları.
ATE265854T1 (de)	2004-05-15	Azasteroidverbindung zur behandlung oder vorbeugung von prostatakrebs
BR0210201A (pt)	2004-06-08	Composição
ATE310111T1 (de)	2005-12-15	Verwendung von organischen karbonaten als lösungsmittel zur reinigung von metalloberflächen
DE60318033D1 (de)	2008-01-24	Biguanid-derivate und deren verwendung als antidiabetika
ES2058783T3 (es)	1994-11-01	Composiciones contra algas que contienen difenileteres e isotiazolonas, procedimientos de control de algas, y composiciones de recubrimiento que contienen las composiciones contra algas.