ATE45578T1 - Synthese von inotropem imidazo(4,5-c>pyridin. - Google Patents
Synthese von inotropem imidazo(4,5-c>pyridin.Info
- Publication number
- ATE45578T1 ATE45578T1 AT86302225T AT86302225T ATE45578T1 AT E45578 T1 ATE45578 T1 AT E45578T1 AT 86302225 T AT86302225 T AT 86302225T AT 86302225 T AT86302225 T AT 86302225T AT E45578 T1 ATE45578 T1 AT E45578T1
- Authority
- AT
- Austria
- Prior art keywords
- pyridine
- imidazo
- inotropic
- synthesis
- methoxy
- Prior art date
Links
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title abstract 4
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 230000000297 inotrophic effect Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- ZCCYWTNAKNQRES-UHFFFAOYSA-N 2-methoxy-4-methylbenzenecarbothioic s-acid Chemical compound COC1=CC(C)=CC=C1C(O)=S ZCCYWTNAKNQRES-UHFFFAOYSA-N 0.000 abstract 1
- OYTKINVCDFNREN-UHFFFAOYSA-N amifampridine Chemical compound NC1=CC=NC=C1N OYTKINVCDFNREN-UHFFFAOYSA-N 0.000 abstract 1
- 229960004012 amifampridine Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Exhaust Gas After Treatment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71800085A | 1985-03-29 | 1985-03-29 | |
| EP86302225A EP0196224B1 (de) | 1985-03-29 | 1986-03-26 | Synthese von inotropem Imidazo[4,5-c]pyridin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE45578T1 true ATE45578T1 (de) | 1989-09-15 |
Family
ID=24884411
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86302225T ATE45578T1 (de) | 1985-03-29 | 1986-03-26 | Synthese von inotropem imidazo(4,5-c>pyridin. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0196224B1 (de) |
| JP (1) | JPS61229878A (de) |
| KR (1) | KR870000930B1 (de) |
| AT (1) | ATE45578T1 (de) |
| CA (1) | CA1295330C (de) |
| DE (1) | DE3665064D1 (de) |
| HU (1) | HU195219B (de) |
| IL (1) | IL78241A0 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5322672B2 (ja) * | 2008-11-28 | 2013-10-23 | 住友化学株式会社 | ジベンゾオキセピン化合物の製造方法 |
| JP7240004B2 (ja) | 2017-07-27 | 2023-03-15 | アドシア | 少なくともヒトインスリンa21gおよび食事作用性グルカゴンサプレッサーを含む水溶液注射剤の形態の組成物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3273461D1 (en) * | 1981-08-19 | 1986-10-30 | Merck Patent Gmbh | 2-arylimidazopyridines |
| ES8401486A1 (es) * | 1981-11-10 | 1983-12-01 | Wellcome Found | Un procedimiento para la preparacion de nuevos derivados de imidazo (4,5-c)piridina. |
| IL68495A0 (en) * | 1982-05-03 | 1983-07-31 | Lilly Co Eli | 2-phenylimidazo(4,5-c)pyridines |
-
1986
- 1986-03-24 CA CA000504917A patent/CA1295330C/en not_active Expired - Lifetime
- 1986-03-24 IL IL78241A patent/IL78241A0/xx not_active IP Right Cessation
- 1986-03-26 EP EP86302225A patent/EP0196224B1/de not_active Expired
- 1986-03-26 DE DE8686302225T patent/DE3665064D1/de not_active Expired
- 1986-03-26 AT AT86302225T patent/ATE45578T1/de active
- 1986-03-27 KR KR8602289A patent/KR870000930B1/ko not_active Expired
- 1986-03-27 HU HU861298A patent/HU195219B/hu not_active IP Right Cessation
- 1986-03-28 JP JP61072383A patent/JPS61229878A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HU195219B (en) | 1988-04-28 |
| DE3665064D1 (en) | 1989-09-21 |
| HUT40655A (en) | 1987-01-28 |
| KR860007258A (ko) | 1986-10-10 |
| EP0196224A1 (de) | 1986-10-01 |
| CA1295330C (en) | 1992-02-04 |
| IL78241A0 (en) | 1986-07-31 |
| EP0196224B1 (de) | 1989-08-16 |
| JPS61229878A (ja) | 1986-10-14 |
| KR870000930B1 (en) | 1987-05-11 |
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