ATE456773T1 - Kryolagerungssystem und -verfahren mit gesteuerter geschwindigkeit der dentritischen gefrierfront - Google Patents

Kryolagerungssystem und -verfahren mit gesteuerter geschwindigkeit der dentritischen gefrierfront

Info

Publication number
ATE456773T1
ATE456773T1 AT02752333T AT02752333T ATE456773T1 AT E456773 T1 ATE456773 T1 AT E456773T1 AT 02752333 T AT02752333 T AT 02752333T AT 02752333 T AT02752333 T AT 02752333T AT E456773 T1 ATE456773 T1 AT E456773T1
Authority
AT
Austria
Prior art keywords
sterile container
flexible sterile
biopharmaceutical
cryopreservation
freezing
Prior art date
Application number
AT02752333T
Other languages
English (en)
Inventor
Richard Wisniewski
Eric Lee
Original Assignee
Sartorius Stedim Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sartorius Stedim Systems Inc filed Critical Sartorius Stedim Systems Inc
Application granted granted Critical
Publication of ATE456773T1 publication Critical patent/ATE456773T1/de

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25C—PRODUCING, WORKING OR HANDLING ICE
    • F25C1/00—Producing ice
    • F25C1/04—Producing ice by using stationary moulds
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
    • F25B2600/00—Control issues
    • F25B2600/07—Remote controls
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25C—PRODUCING, WORKING OR HANDLING ICE
    • F25C2600/00—Control issues
    • F25C2600/04—Control means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/42—Low-temperature sample treatment, e.g. cryofixation

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Mechanical Engineering (AREA)
  • Thermal Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Packages (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cooling Or The Like Of Electrical Apparatus (AREA)
  • Devices That Are Associated With Refrigeration Equipment (AREA)
  • Vending Machines For Individual Products (AREA)
  • Molding Of Porous Articles (AREA)
  • Continuous Casting (AREA)
AT02752333T 2001-07-13 2002-07-15 Kryolagerungssystem und -verfahren mit gesteuerter geschwindigkeit der dentritischen gefrierfront ATE456773T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/905,488 US6453683B1 (en) 2001-05-22 2001-07-13 Tapered slot cryopreservation system with controlled dendritic freezing front velocity
PCT/US2002/022378 WO2003006899A1 (en) 2001-07-13 2002-07-15 Cryopreservation system with controlled dendritic freezing front velocity

Publications (1)

Publication Number Publication Date
ATE456773T1 true ATE456773T1 (de) 2010-02-15

Family

ID=25420922

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02752333T ATE456773T1 (de) 2001-07-13 2002-07-15 Kryolagerungssystem und -verfahren mit gesteuerter geschwindigkeit der dentritischen gefrierfront

Country Status (8)

Country Link
US (1) US6453683B1 (de)
EP (1) EP1407202B1 (de)
JP (1) JP2004534601A (de)
CN (1) CN1283966C (de)
AT (1) ATE456773T1 (de)
CA (1) CA2453436A1 (de)
DE (1) DE60235239D1 (de)
WO (1) WO2003006899A1 (de)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6684646B2 (en) 2001-05-22 2004-02-03 Integrated Biosystems, Inc. Systems and methods for freezing, storing and thawing biopharmaceutical material
US6945056B2 (en) * 2001-11-01 2005-09-20 Integrated Biosystems, Inc. Systems and methods for freezing, mixing and thawing biopharmaceutical material
US6698213B2 (en) * 2001-05-22 2004-03-02 Integrated Biosystems, Inc. Systems and methods for freezing and storing biopharmaceutical material
US7104074B2 (en) * 2001-11-01 2006-09-12 Integrated Biosystems, Inc. Systems and methods for freezing, storing, transporting and thawing biopharmaceutical material
US6981794B2 (en) * 2002-04-12 2006-01-03 Hynetics Llc Methods for mixing solutions
US6908223B2 (en) 2002-04-12 2005-06-21 Hynetics Llc Systems for mixing liquid solutions and methods of manufacture
US6923567B2 (en) * 2002-04-12 2005-08-02 Hynetics Llc Mixing tank assembly
ATE328776T1 (de) 2002-09-23 2006-06-15 Integrated Biosystems Inc Verfahren und vorrichtung zum einfrieren, lagern, befördern und auftauen von biopharmazeutischem material
US6837610B2 (en) * 2002-09-27 2005-01-04 Ilc Dover Lpp Bioprocess container, bioprocess container mixing device and method of use thereof
WO2004055456A1 (en) * 2002-12-13 2004-07-01 Integrated Biosystems, Inc. Scaled down freezing and thawing system for bioparmaceuticals and biologics
US20070077237A1 (en) * 2003-10-09 2007-04-05 Udi Damari Method for freezing, thawing and transplantation of viable cartilage
US20050241333A1 (en) * 2003-12-03 2005-11-03 Hamilton Robert W Rate-controlled freezer and cooling methods thereof
EP1711214A1 (de) * 2004-02-02 2006-10-18 Interface Multigrad Technology (IMT) Ltd. Vorrichtung zum gerichteten kühlen von biomasse
WO2005072523A2 (en) * 2004-02-02 2005-08-11 I.M.T. Interface Multigrad Technology Ltd. Biological material and methods and solutions for preservation thereof
US7892726B2 (en) * 2004-06-07 2011-02-22 Core Dynamics Limited Method for sterilizing lyophilized eukaryotic anuclear cells with gamma irradiation
EP1778007A1 (de) * 2004-08-12 2007-05-02 I.M.T. Interface Multigrad Technology Ltd. Verfahren und gerät zum einfrieren bzw. auftauen von biologischem material
EP1850661A2 (de) * 2005-02-22 2007-11-07 Interface Multigrad Technology (IMT) Ltd. Konservierter lebensfähiger knorpel, verfahren zu seiner konservierung, sowie hierfür verwendete(s) system und geräte
US20060243666A1 (en) * 2005-04-29 2006-11-02 Jenkins Lauri L Process for the preparation of protein separation solution
US20060246008A1 (en) * 2005-04-29 2006-11-02 Jenkins Lauri L Process for the formulation of therapeutic protein
US20060246244A1 (en) * 2005-04-29 2006-11-02 Jenkins Lauri L Disposable vessel for the containment of biological materials and corrosive reagents
US20060246537A1 (en) * 2005-04-29 2006-11-02 Jenkins Lauri L Multi-step process for the manufacture of therapeutic protein
US20060246546A1 (en) * 2005-04-29 2006-11-02 Jenkins Lauri L Manufacture of biologic cellular products
EP1909565A2 (de) * 2005-08-03 2008-04-16 Interface Multigrad Technology (IMT) Ltd. Somatische zellen für die zelltherapie
JP2009518242A (ja) * 2005-12-02 2009-05-07 スミスクライン・ビーチャム・コーポレイション バイオ医薬品製剤の凍結貯蔵容器
US20070137842A1 (en) * 2005-12-20 2007-06-21 Philippe Lam Heating and cooling system for biological materials
EP1986493A1 (de) * 2006-02-13 2008-11-05 I.M.T. Interface Multigrad Technology Ltd. Tiefgefrorene lebensfähige feste organe und tiefgefrierverfahren hierfür
EP2113171B1 (de) 2006-03-06 2016-11-02 Sartorius Stedim North America Inc. Systeme und Verfahren zum Einfrieren, Lagern und Auftauen biopharmazeutischer Materialien
US20090094995A1 (en) * 2006-06-15 2009-04-16 Air Liquide Industrial U.S. Lp System and method for processing food products with fluid recirculation and chilling
US20100281886A1 (en) * 2006-09-11 2010-11-11 Core Dynamics Limited Systems, devices and methods for freezing and thawing biological materials
US8177123B2 (en) * 2008-09-24 2012-05-15 Sartorius Stedim North America Inc. Systems and methods for freezing, storing and thawing biopharmaceutical materials
US9301520B2 (en) * 2007-12-21 2016-04-05 Sartorius Stedim North America Inc. Systems and methods for freezing, storing and thawing biopharmaceutical materials
US20090202978A1 (en) * 2008-02-13 2009-08-13 Ginadi Shaham Method and apparatus for freezing of a biological material
DK2387686T3 (da) * 2009-01-13 2019-09-30 Emd Millipore Corp Forbedret biomaterialefrysning
ES2743693T3 (es) * 2009-04-29 2020-02-20 Biolife Solutions Inc Aparatos y composiciones para crioconservación de monocapas celulares
WO2011048031A1 (de) 2009-10-19 2011-04-28 Boehringer Ingelheim International Gmbh Behälter für pharmazeutisches material
CN102741244A (zh) 2009-10-26 2012-10-17 拜耳作物科学公司 4-[[(6-氯吡啶-3-基)甲基](2,2-二氟乙基)氨基]呋喃-2(5h)-酮的新固体形式
US8448457B2 (en) * 2009-11-23 2013-05-28 Sartorius Stedim North America Inc. Systems and methods for use in freezing, thawing, and storing biopharmaceutical materials
US8371132B2 (en) * 2009-11-23 2013-02-12 Sartorius Stedim North America Inc. Systems and methods for use in freezing, thawing, and storing biopharmaceutical materials
PT105405B (pt) 2010-11-26 2014-08-21 Univ Lisboa Processo e aparelho de congelação em pratos para obtenção de matrizes de gelo com distribuição de solutos uniforme
US20140047851A1 (en) * 2011-03-28 2014-02-20 Praxair Technology, Inc. Bulk freezing of biopharmaceuticals
FR3003644B1 (fr) * 2013-03-22 2015-03-20 Sartorius Stedim North America Inc Controle de l'etat de congelation d'un fluide biopharmaceutique se trouvant dans un conteneur.
FR3003550B1 (fr) 2013-03-22 2016-05-06 Sartorius Stedim North America Inc Installation et procede pour la preparation d'un conteneur charge avec un fluide biopharmaceutique.
CR20160162A (es) * 2013-09-25 2016-08-29 Saint Gobain Performance Plastics Corp Recipiente para crioconservación
PT107427B (pt) 2014-01-28 2021-01-04 Inst Superior Tecnico Sistema e método de preservação, armazenamento e transporte de materiais biológicos.
CN104132494A (zh) * 2014-08-18 2014-11-05 太仓派欧技术咨询服务有限公司 一种多内胆分离式长效冷藏柜
GB2537797B (en) * 2014-09-24 2019-01-02 The Sure Chill Company Ltd Cooling apparatus and method
US20190191693A1 (en) 2016-08-24 2019-06-27 Merck Sharp & Dohme Corp. Container System and Method for Freezing and Thawing a Liquid Product
WO2018211437A1 (en) 2017-05-16 2018-11-22 Smartfreez Lda System for scale-down the processes of freezing and thawing aqueous solutions of thermo-sensitive pharmaceuticals
AT521596A1 (de) 2018-09-05 2020-03-15 Single Use Support Gmbh Kühlplattenanordnung und Verfahren
US12302895B2 (en) * 2018-11-15 2025-05-20 Smartfreez Lda Device and method for freezing a biological solution
CN109964921A (zh) * 2019-02-25 2019-07-05 天津美电医疗科技有限公司 冰点以下温度保存生物物质的多相定容装置、系统和方法
US11590056B2 (en) * 2020-07-30 2023-02-28 Sartorius Stedim North America Freeze/thaw containment system for flexible pouch filled with biopharmaceutical fluid, and method of assembling a freeze/thaw containment system, using a protecting body
US12239127B2 (en) 2021-07-28 2025-03-04 Sartorius Stedim North America Inc. Thermal capacitors, systems, and methods for rapid freezing or heating of biological materials
WO2023240219A1 (en) * 2022-06-09 2023-12-14 Packaging Systems Cold Chain Llc Cold pack
CN120385670B (zh) * 2025-06-26 2025-09-09 北京理工大学 一种基于冰水液固相变的溶液中金属离子检测装置及方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2662520A (en) * 1951-02-06 1953-12-15 Little Inc A Preservation and storage of biological materials
US2775101A (en) * 1952-11-07 1956-12-25 Carrier Corp Self-contained ice making unit
US3121627A (en) * 1961-07-24 1964-02-18 Water Process Corp Method of purifying water by freezing
US3959981A (en) * 1974-08-08 1976-06-01 Anderson Luzon L Apparatus for preparing ice
IT1228889B (it) * 1989-02-24 1991-07-09 Sidam Srl Macchina per la produzione di gelati e ghiaccioli a due o piu' strati concentrici o comunque abbinati, in particolare gelati con stecco, e relativo procedimento di produzione
DE4023664C1 (en) * 1990-07-25 1991-08-14 Bosch-Siemens Hausgeraete Gmbh, 8000 Muenchen, De Clear ice-cubes formation in refrigerator - involves double profiled bowl in insulated base container holding eutectic solution
US5374436A (en) * 1993-09-29 1994-12-20 White; Neal E. Apparatus and method for making a multi-flavored frozen confection
US5582856A (en) * 1995-12-18 1996-12-10 White; Neal E. Apparatus and method for making a multi-flavored frozen confection
US6082121A (en) * 1999-04-02 2000-07-04 Group Dekko Services, Llc. Ice maker

Also Published As

Publication number Publication date
CA2453436A1 (en) 2003-01-23
WO2003006899A1 (en) 2003-01-23
US6453683B1 (en) 2002-09-24
HK1068943A1 (en) 2005-05-06
JP2004534601A (ja) 2004-11-18
EP1407202A1 (de) 2004-04-14
EP1407202B1 (de) 2010-01-27
CN1283966C (zh) 2006-11-08
EP1407202A4 (de) 2009-05-27
CN1527927A (zh) 2004-09-08
DE60235239D1 (de) 2010-03-18

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