ATE457038T1 - Genetisch modifizierte streptomyces-stämme für biotransformationen bei der anthracyclin- herstellung - Google Patents

Genetisch modifizierte streptomyces-stämme für biotransformationen bei der anthracyclin- herstellung

Info

Publication number: ATE457038T1
Authority: AT; Austria
Prior art keywords: biotransformations; genetically modified; anthracycline; streptomyces strains; modified streptomyces
Prior art date: 2007-08-24

Application number

AT07016622T

Other languages

English (en)

Inventor

Michael Lambert

Kristiina Ylihonko

Maria Holmbaeck

Original Assignee

Heraeus Gmbh W C

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-08-24

Filing date

2007-08-24

Publication date

2010-02-15

2007-08-24 Application filed by Heraeus Gmbh W C filed Critical Heraeus Gmbh W C

2010-02-15 Application granted granted Critical

2010-02-15 Publication of ATE457038T1 publication Critical patent/ATE457038T1/de

Links

229940045799 anthracyclines and related substance Drugs 0.000 title abstract 3
241000187747 Streptomyces Species 0.000 title 1
239000002207 metabolite Substances 0.000 abstract 2
230000000813 microbial effect Effects 0.000 abstract 2
239000003817 anthracycline antibiotic agent Substances 0.000 abstract 1
239000003242 anti bacterial agent Substances 0.000 abstract 1
229940088710 antibiotic agent Drugs 0.000 abstract 1
STQGQHZAVUOBTE-VGBVRHCVSA-N daunorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(C)=O)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 STQGQHZAVUOBTE-VGBVRHCVSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT07016622T 2007-08-24 2007-08-24 Genetisch modifizierte streptomyces-stämme für biotransformationen bei der anthracyclin- herstellung ATE457038T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP07016622A EP2042608B1 (de)	2007-08-24	2007-08-24	Genetisch modifizierte Streptomyces-Stämme für Biotransformationen bei der Anthracyclin-Herstellung

Publications (1)

Publication Number	Publication Date
ATE457038T1 true ATE457038T1 (de)	2010-02-15

Family

ID=38983538

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT07016622T ATE457038T1 (de)	2007-08-24	2007-08-24	Genetisch modifizierte streptomyces-stämme für biotransformationen bei der anthracyclin- herstellung

Country Status (7)

Country	Link
EP (1)	EP2042608B1 (de)
AT (1)	ATE457038T1 (de)
DE (1)	DE602007004672D1 (de)
ES (1)	ES2338596T3 (de)
PL (1)	PL2042608T3 (de)
PT (1)	PT2042608E (de)
TW (1)	TW200916576A (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN103882005B (zh) *	2014-02-20	2016-06-29	中国科学院寒区旱区环境与工程研究所	链霉菌菌株spc6-50-1的诱变筛选方法及应用
DE102014208194A1 (de)	2014-04-30	2015-11-05	Heraeus Deutschland GmbH & Co. KG	Aufreinigung von Epidaunorubicin
CN107541481B (zh) *	2016-06-23	2021-07-02	上海医药工业研究院	一种产表阿霉素的基因工程菌及其应用
CN111187746B (zh) *	2018-11-15	2022-11-22	上海医药工业研究院	一种基因工程菌及其制备方法和应用

2007
- 2007-08-24 EP EP07016622A patent/EP2042608B1/de not_active Not-in-force
- 2007-08-24 ES ES07016622T patent/ES2338596T3/es active Active
- 2007-08-24 AT AT07016622T patent/ATE457038T1/de not_active IP Right Cessation
- 2007-08-24 PL PL07016622T patent/PL2042608T3/pl unknown
- 2007-08-24 DE DE602007004672T patent/DE602007004672D1/de active Active
- 2007-08-24 PT PT07016622T patent/PT2042608E/pt unknown
2008
- 2008-08-22 TW TW097132264A patent/TW200916576A/zh unknown

Also Published As

Publication number	Publication date
EP2042608A1 (de)	2009-04-01
TW200916576A (en)	2009-04-16
PL2042608T3 (pl)	2010-06-30
PT2042608E (pt)	2010-03-22
DE602007004672D1 (de)	2010-03-25
ES2338596T3 (es)	2010-05-10
EP2042608B1 (de)	2010-02-03

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Legal Events

Date	Code	Title	Description
2010-08-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties