ATE457068T1 - Vorrichtung und verfahren zur durchführung von in-vitro-dnp-nmr-messungen - Google Patents
Vorrichtung und verfahren zur durchführung von in-vitro-dnp-nmr-messungenInfo
- Publication number
- ATE457068T1 ATE457068T1 AT05744830T AT05744830T ATE457068T1 AT E457068 T1 ATE457068 T1 AT E457068T1 AT 05744830 T AT05744830 T AT 05744830T AT 05744830 T AT05744830 T AT 05744830T AT E457068 T1 ATE457068 T1 AT E457068T1
- Authority
- AT
- Austria
- Prior art keywords
- sample
- dnp
- nmr
- magnetic field
- working region
- Prior art date
Links
- 238000005481 NMR spectroscopy Methods 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 3
- 238000000338 in vitro Methods 0.000 title abstract 2
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/62—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using double resonance
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/30—Sample handling arrangements, e.g. sample cells, spinning mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/46—NMR spectroscopy
Landscapes
- Physics & Mathematics (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- High Energy & Nuclear Physics (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Measurement Of Current Or Voltage (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0411072.2A GB0411072D0 (en) | 2004-05-18 | 2004-05-18 | Apparatus and method for performing in-vitro dnp-nmr measurements |
| PCT/GB2005/001873 WO2005114244A1 (en) | 2004-05-18 | 2005-05-16 | Apparatus and method for performing in-vitro dnp-nmr measurements |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE457068T1 true ATE457068T1 (de) | 2010-02-15 |
Family
ID=32607522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05744830T ATE457068T1 (de) | 2004-05-18 | 2005-05-16 | Vorrichtung und verfahren zur durchführung von in-vitro-dnp-nmr-messungen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7639007B2 (de) |
| EP (1) | EP1747478B1 (de) |
| JP (1) | JP4340318B2 (de) |
| AT (1) | ATE457068T1 (de) |
| DE (1) | DE602005019233D1 (de) |
| GB (1) | GB0411072D0 (de) |
| WO (1) | WO2005114244A1 (de) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0424725D0 (en) * | 2004-11-09 | 2004-12-08 | Oxford Instr Superconductivity | Cryostat assembly |
| GB0605031D0 (en) * | 2006-03-13 | 2006-04-19 | Oxford Instr Molecular Biotool | NMR inspection apparatus |
| GB2443674B (en) * | 2006-10-04 | 2008-11-26 | Oxford Instr Superconductivity | Flow-cooled magnet system |
| US7631507B2 (en) * | 2006-11-02 | 2009-12-15 | General Electric Company | Methods and devices for polarized samples for use in MRI |
| US8731640B2 (en) | 2007-03-28 | 2014-05-20 | General Electric Company | Fluid path system for dissolution and transport of a hyperpolarized material |
| US20140123681A1 (en) * | 2007-04-02 | 2014-05-08 | General Electric Company | Method and apparatus to hyperpolarize materials for enhanced mr techniques |
| US20080242974A1 (en) * | 2007-04-02 | 2008-10-02 | Urbahn John A | Method and apparatus to hyperpolarize materials for enhanced mr techniques |
| US7906962B2 (en) * | 2007-08-24 | 2011-03-15 | The Regents Of The University Of California | Dynamic nuclear polarization enhanced nuclear magnetic resonance of water under ambient conditions |
| EP2028505A3 (de) | 2007-08-24 | 2010-03-17 | Oxford Instruments Molecular Biotools Ltd. | Kühleinheit einer DNP-Vorrichtung |
| WO2009027645A2 (en) * | 2007-08-24 | 2009-03-05 | The Universtiy Of Nottingham | Improvements in the preparation of a sample (e.g. involving dynamic nuclear polarisation) for analysis (e.g. by nmr or mri) |
| DE102008033886B4 (de) * | 2008-07-18 | 2012-03-08 | Bruker Biospin Ag | Apparatur zur Durchführung von DNP-NMR Messungen mit Kompensationsanordnung |
| US7633290B1 (en) | 2008-09-09 | 2009-12-15 | General Electric Company | Apparatus and method for a fully automated preparation of a hyperpolarizing imaging agent |
| US9234691B2 (en) * | 2010-03-11 | 2016-01-12 | Quantum Design International, Inc. | Method and apparatus for controlling temperature in a cryocooled cryostat using static and moving gas |
| US8970217B1 (en) | 2010-04-14 | 2015-03-03 | Hypres, Inc. | System and method for noise reduction in magnetic resonance imaging |
| US9618257B2 (en) * | 2010-06-09 | 2017-04-11 | Quantum Design International, Inc. | Gas-flow cryostat for dynamic temperature regulation using a fluid level sensor |
| US20130237803A1 (en) * | 2010-11-16 | 2013-09-12 | Aspect Imaging Ltd. | System and Method for Generating Invasively Hyperpolarized Images |
| US8786284B2 (en) * | 2011-01-11 | 2014-07-22 | Bridge12 Technologies, Inc. | Integrated high-frequency generator system utilizing the magnetic field of the target application |
| DE102011013577B4 (de) * | 2011-03-10 | 2013-02-28 | Karlsruher Institut für Technologie | Vorrichtung zur Speicherung von Wasserstoff und von magnetischer Energie sowie ein Verfahren zu ihrem Betrieb |
| WO2012126366A2 (zh) * | 2011-03-21 | 2012-09-27 | 爱里程科技咨询(上海)有限公司 | 一种优化dnp的磁共振设备和方法 |
| DE102011005888B4 (de) * | 2011-03-22 | 2014-01-09 | Bruker Biospin Ag | Kühlung eines Kryo-Probenkopfes in einer Kernspinresonanz-Apparatur |
| US9110132B2 (en) * | 2011-08-05 | 2015-08-18 | Chris Chiodo | Electrical and fluid connection system for magnetic imaging |
| EP2795355B1 (de) | 2011-12-23 | 2019-04-03 | Stichting Katholieke Universiteit | Kernmagnetresonanzvorrichtung mit schneller zyklischer dynamischer nuklearer polarisierung |
| GB2498181A (en) * | 2011-12-29 | 2013-07-10 | Bruker Biospin Gmbh | Device and method for rapid dynamic nuclear polarisation |
| EP2992344B1 (de) * | 2013-05-03 | 2020-10-07 | Quantum Valley Investment Fund LP | Spinpolarisationsübertragung |
| CA2910547C (en) | 2013-05-03 | 2020-03-10 | Quantum Valley Investment Fund LP | Using a thermally-isolated cavity to polarize a spin ensemble |
| DE102013212312B4 (de) * | 2013-06-26 | 2017-02-02 | Bruker Biospin Ag | NMR-Probenkopf mit verbesserter Zentrierung des Probenröhrchens |
| US10184711B2 (en) | 2014-05-19 | 2019-01-22 | General Electric Company | Cryogenic cooling system |
| JP6434231B2 (ja) * | 2014-06-23 | 2018-12-05 | 住友ゴム工業株式会社 | 動的核スピン偏極実験用高分子複合材料とその作製方法 |
| DE102014225481A1 (de) * | 2014-12-10 | 2016-06-16 | Bruker Biospin Gmbh | Kryostat mit einem ersten und einem zweiten Heliumtank, die zumindest in einem unteren Bereich flüssigkeitsdicht voneinander abgetrennt sind |
| US10088536B2 (en) * | 2015-03-27 | 2018-10-02 | Bruker Biospin Corporation | Sample introduction system and method for polarization |
| WO2016163021A1 (ja) * | 2015-04-10 | 2016-10-13 | 三菱電機株式会社 | 超電導マグネット |
| EP3081954B1 (de) * | 2015-04-13 | 2018-07-25 | Bruker France S.A.S. | Verfahren für kernmagnetische resonanzmessungen mit zwei magnetfeldern |
| WO2016170153A1 (en) * | 2015-04-23 | 2016-10-27 | Universidad De Zaragoza | Method for cooling cryogenic liquids and system associated to said method |
| WO2016179523A1 (en) * | 2015-05-06 | 2016-11-10 | The Regents Of The University Of California | Apparatus and method for nuclear magnetic resonance utilizing dynamic nuclear polarization |
| GB201517391D0 (en) * | 2015-10-01 | 2015-11-18 | Iceoxford Ltd | Cryogenic apparatus |
| JP6602716B2 (ja) * | 2016-03-30 | 2019-11-06 | ジャパンスーパーコンダクタテクノロジー株式会社 | 超電導マグネット装置 |
| JP6546115B2 (ja) * | 2016-03-30 | 2019-07-17 | ジャパンスーパーコンダクタテクノロジー株式会社 | 超電導マグネット装置 |
| EP4607201A3 (de) | 2016-07-21 | 2025-10-22 | Siemens Healthcare Diagnostics, Inc. | Magnetische abschirmung für ivd-automatisierungssystem |
| US10892526B2 (en) * | 2016-08-22 | 2021-01-12 | Georgetown University | Stripline detector for in situ battery NMR |
| WO2019029161A1 (zh) * | 2017-08-10 | 2019-02-14 | 中国科学技术大学 | 脉冲式电子顺磁共振谱仪 |
| CN109387799B (zh) * | 2017-08-10 | 2025-01-24 | 中国科学技术大学 | 脉冲式电子顺磁共振谱仪 |
| CN111810134B (zh) * | 2019-12-26 | 2024-03-26 | 北京默凯斯威能源技术有限公司 | 一种石油核磁共振测井仪探头磁体装置 |
| DE102020214887B4 (de) | 2020-11-26 | 2022-08-04 | Bruker Switzerland Ag | Magnetsystem zur Durchführung von 2-Feld-NMR-Experimenten und zugehöriges Nachrüstverfahren |
| CN115753868B (zh) * | 2022-12-05 | 2023-06-20 | 中国科学院精密测量科学与技术创新研究院 | 一种用于dDNP的可变温广谱光诱导自由基生成的装置和方法 |
| CN116223554B (zh) * | 2023-05-09 | 2023-08-04 | 中国科学院精密测量科学与技术创新研究院 | 一种用于dDNP探针分子多通道代谢示踪检测的装置和方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1330659T3 (da) | 2000-11-03 | 2006-12-18 | Amersham Health As | Fremgangsmåde og indretning til oplösning af hyperpolariseret, fast materiale til NMR-analyser |
| US6515260B1 (en) * | 2001-11-07 | 2003-02-04 | Varian, Inc. | Method and apparatus for rapid heating of NMR samples |
| DE102004005744B4 (de) * | 2004-02-05 | 2007-12-20 | Bruker Biospin Gmbh | Driftkompensiertes supraleitendes Magnetsystem |
| GB0501346D0 (en) * | 2005-01-21 | 2005-03-02 | Oxford Instr Molecular Biotool | Method of carrying out dynamic nuclear polarization |
-
2004
- 2004-05-18 GB GBGB0411072.2A patent/GB0411072D0/en not_active Ceased
-
2005
- 2005-05-16 DE DE602005019233T patent/DE602005019233D1/de not_active Expired - Lifetime
- 2005-05-16 US US11/569,130 patent/US7639007B2/en not_active Expired - Fee Related
- 2005-05-16 JP JP2007517405A patent/JP4340318B2/ja not_active Expired - Fee Related
- 2005-05-16 WO PCT/GB2005/001873 patent/WO2005114244A1/en not_active Ceased
- 2005-05-16 AT AT05744830T patent/ATE457068T1/de not_active IP Right Cessation
- 2005-05-16 EP EP05744830A patent/EP1747478B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1747478A1 (de) | 2007-01-31 |
| EP1747478B1 (de) | 2010-02-03 |
| DE602005019233D1 (de) | 2010-03-25 |
| GB0411072D0 (en) | 2004-06-23 |
| JP2007538244A (ja) | 2007-12-27 |
| WO2005114244A1 (en) | 2005-12-01 |
| JP4340318B2 (ja) | 2009-10-07 |
| US7639007B2 (en) | 2009-12-29 |
| US20080290869A1 (en) | 2008-11-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |