ATE457163T1 - Verwendung von ciclesonide zur erhaltung des feinen teilchengrössenanteils von formoterol - Google Patents

Verwendung von ciclesonide zur erhaltung des feinen teilchengrössenanteils von formoterol

Info

Publication number: ATE457163T1
Authority: AT; Austria
Prior art keywords: ciclesonide; formoterol; maintain; particle size; fine particle
Prior art date: 2003-05-28

Application number

AT04735045T

Other languages

English (en)

Inventor

Nicholas Heaton

Zoe Heaton

Original Assignee

Nycomed Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-05-28

Filing date

2004-05-27

Publication date

2010-02-15

2004-05-27 Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh

2010-02-15 Application granted granted Critical

2010-02-15 Publication of ATE457163T1 publication Critical patent/ATE457163T1/de

Links

LUKZNWIVRBCLON-GXOBDPJESA-N Ciclesonide Chemical compound C1([C@H]2O[C@@]3([C@H](O2)C[C@@H]2[C@@]3(C[C@H](O)[C@@H]3[C@@]4(C)C=CC(=O)C=C4CC[C@H]32)C)C(=O)COC(=O)C(C)C)CCCCC1 LUKZNWIVRBCLON-GXOBDPJESA-N 0.000 title 1
229960003728 ciclesonide Drugs 0.000 title 1
239000010419 fine particle Substances 0.000 title 1
BPZSYCZIITTYBL-UHFFFAOYSA-N formoterol Chemical compound C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-UHFFFAOYSA-N 0.000 title 1
229960002848 formoterol Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/24—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
- B65D81/26—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/24—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
- B65D81/26—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators
- B65D81/266—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators for absorbing gases, e.g. oxygen absorbers or desiccants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2209/00—Ancillary equipment
- A61M2209/06—Packaging for specific medical equipment

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Pulmonology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Food Science & Technology (AREA)
Mechanical Engineering (AREA)
Otolaryngology (AREA)
Inorganic Chemistry (AREA)
Anesthesiology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)

AT04735045T 2003-05-28 2004-05-27 Verwendung von ciclesonide zur erhaltung des feinen teilchengrössenanteils von formoterol ATE457163T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0312148.0A GB0312148D0 (en)	2003-05-28	2003-05-28	Stabilized pharmaceutical products
PCT/GB2004/002249 WO2004105727A2 (en)	2003-05-28	2004-05-27	Stabilized pharmaceutical product

Publications (1)

Publication Number	Publication Date
ATE457163T1 true ATE457163T1 (de)	2010-02-15

Family

ID=9958829

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04735045T ATE457163T1 (de)	2003-05-28	2004-05-27	Verwendung von ciclesonide zur erhaltung des feinen teilchengrössenanteils von formoterol

Country Status (22)

Country	Link
US (4)	US7736673B2 (de)
EP (1)	EP1626913B1 (de)
JP (1)	JP5175048B2 (de)
KR (1)	KR20060023539A (de)
CN (1)	CN1832890A (de)
AR (1)	AR047619A1 (de)
AT (1)	ATE457163T1 (de)
AU (1)	AU2004243223A1 (de)
BR (1)	BRPI0410701A (de)
CA (1)	CA2527088C (de)
DE (1)	DE602004025463D1 (de)
ES (1)	ES2340681T3 (de)
GB (1)	GB0312148D0 (de)
MA (1)	MA27804A1 (de)
MX (1)	MXPA05012757A (de)
NO (1)	NO20055443L (de)
PL (1)	PL1626913T3 (de)
RS (1)	RS20050882A (de)
RU (1)	RU2337667C2 (de)
TW (1)	TW200509989A (de)
WO (1)	WO2004105727A2 (de)
ZA (1)	ZA200509099B (de)

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AU2003293833B2 (en)	2002-12-12	2009-10-01	Covis Pharma B.V.	Combination medicament
GB0312148D0 (en) *	2003-05-28	2003-07-02	Aventis Pharma Ltd	Stabilized pharmaceutical products
CA2528479A1 (en)	2003-06-13	2004-12-23	Altana Pharma Ag	Formoterol and ciclesonide combination
GB0315889D0 (en)	2003-07-08	2003-08-13	Aventis Pharma Ltd	Stable pharmaceutical products
EP1803457A1 (de) *	2005-12-30	2007-07-04	Krka Tovarna Zdravil, D.D., Novo Mesto	Pharmazeutische Zubereitung, welche Montelukast enthält
PL1976522T5 (pl) *	2005-12-30	2019-12-31	Krka Tovarna Zdravil, D.D., Novo Mesto	Kompozycja farmaceutyczna zawierająca montelukast
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EP2254630A1 (de) *	2008-02-20	2010-12-01	Boehringer Ingelheim International GmbH	Pulverinhalatoren
PL3578169T3 (pl)	2009-02-26	2024-09-02	Glaxo Group Limited	Preparaty farmaceutyczne zawierające 4-{(1r)-2-[(6-{2-[(2,6-dichlorobenzylo)oksy]etoksy}heksylo)amino]-1-hydroksyetylo}-2-(hydroksymetylo)fenol
GB0921075D0 (en)	2009-12-01	2010-01-13	Glaxo Group Ltd	Novel combination of the therapeutic agents
US9233788B2 (en)	2010-01-22	2016-01-12	Bayer Healthcare Llc	Biosensor desiccant system having enhanced measurement performance
CN102713608B (zh) *	2010-01-22	2016-01-13	拜尔健康护理有限责任公司	改进准确度的除湿剂
WO2011093814A2 (en) *	2010-01-29	2011-08-04	Mahmut Bilgic	A pharmaceutical combination comprising formoterol and ciclesonide
AU2011298409B2 (en)	2010-08-31	2013-11-21	Glaxo Group Limited	Dry powder inhalation drug products exhibiting moisture control properties and methods of administering the same
TR201007250A2 (tr) *	2010-09-01	2012-03-21	Bi̇lgi̇ç Mahmut	Selobioz içeren formülasyon.
TWI565943B (zh) *	2011-07-22	2017-01-11	拜耳保健公司	具有增進測量性能之生物感測器乾燥劑系統
EP2751562B1 (de)	2011-09-02	2015-09-16	Nestec S.A.	Profilierung von signalwegproteinen zur bestimmung der therapeutischen wirksamkeit
WO2013109212A1 (en) *	2012-01-16	2013-07-25	Mahmut Bilgic	Dry powder formulations comprising ciclesonide
KR20130140358A (ko)	2012-06-14	2013-12-24	한미약품 주식회사	살메테롤 지나포산염, 플루티카손 프로피오네이트 및 티오트로피움 브로마이드를 포함하는 흡입 제형용 건조 분말 및 이의 제조방법
EP2954329A1 (de)	2013-02-05	2015-12-16	Nestec S.A.	Verfahren zur auswahl einer kombinationstherapie für darmkrebspatienten
CN104644618A (zh) *	2013-11-19	2015-05-27	上海医药工业研究院	一种干粉吸入剂及其制备方法
US11642309B2 (en) *	2017-10-16	2023-05-09	Faes Farma, S.A.	Aqueous compositions comprising bilastine and mometasone
US10537585B2 (en)	2017-12-18	2020-01-21	Dexcel Pharma Technologies Ltd.	Compositions comprising dexamethasone
US20250050042A1 (en) *	2021-12-21	2025-02-13	Chiesi Farmaceutici S.P.A.	Dry powder formulations filled in an inhaler with improved resistance to humidity

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JP2004051502A (ja) *	2002-07-17	2004-02-19	Jcr Pharmaceuticals Co Ltd	成長ホルモン含有安定化粉末製剤
AU2003293833B2 (en)	2002-12-12	2009-10-01	Covis Pharma B.V.	Combination medicament
EP1635844A1 (de)	2003-05-22	2006-03-22	ALTANA Pharma AG	Kombination aus salmeterol und ciclesonid
GB0312148D0 (en) *	2003-05-28	2003-07-02	Aventis Pharma Ltd	Stabilized pharmaceutical products
EP1636364A2 (de) *	2003-06-06	2006-03-22	Senesco Technologies, Inc.	Hemmung von apoptosespezifischem elf-5a (eif-5a1) mit antisense-oligonukleotiden und sirnas als antiinflammatorische therapeutika
CA2528479A1 (en)	2003-06-13	2004-12-23	Altana Pharma Ag	Formoterol and ciclesonide combination
GB0315889D0 (en) *	2003-07-08	2003-08-13	Aventis Pharma Ltd	Stable pharmaceutical products
GB0323685D0 (en)	2003-10-09	2003-11-12	Jagotec Ag	Improvements in or relating to organic compounds
GB0323684D0 (en)	2003-10-09	2003-11-12	Jagotec Ag	Improvements in or relating to organic compounds

2003
- 2003-05-28 GB GBGB0312148.0A patent/GB0312148D0/en not_active Ceased
2004
- 2004-05-27 EP EP04735045A patent/EP1626913B1/de not_active Expired - Lifetime
- 2004-05-27 BR BRPI0410701-2A patent/BRPI0410701A/pt not_active IP Right Cessation
- 2004-05-27 RU RU2005136869/13A patent/RU2337667C2/ru not_active IP Right Cessation
- 2004-05-27 CA CA2527088A patent/CA2527088C/en not_active Expired - Fee Related
- 2004-05-27 AT AT04735045T patent/ATE457163T1/de not_active IP Right Cessation
- 2004-05-27 KR KR1020057022586A patent/KR20060023539A/ko not_active Withdrawn
- 2004-05-27 ES ES04735045T patent/ES2340681T3/es not_active Expired - Lifetime
- 2004-05-27 JP JP2006530539A patent/JP5175048B2/ja not_active Expired - Lifetime
- 2004-05-27 RS YUP-2005/0882A patent/RS20050882A/sr unknown
- 2004-05-27 PL PL04735045T patent/PL1626913T3/pl unknown
- 2004-05-27 AU AU2004243223A patent/AU2004243223A1/en not_active Abandoned
- 2004-05-27 CN CNA2004800143546A patent/CN1832890A/zh active Pending
- 2004-05-27 TW TW093115016A patent/TW200509989A/zh unknown
- 2004-05-27 WO PCT/GB2004/002249 patent/WO2004105727A2/en not_active Ceased
- 2004-05-27 MX MXPA05012757A patent/MXPA05012757A/es unknown
- 2004-05-27 DE DE602004025463T patent/DE602004025463D1/de not_active Expired - Lifetime
- 2004-05-28 AR ARP040101868A patent/AR047619A1/es not_active Application Discontinuation
2005
- 2005-10-26 US US11/259,495 patent/US7736673B2/en not_active Expired - Lifetime
- 2005-11-10 ZA ZA200509099A patent/ZA200509099B/xx unknown
- 2005-11-11 MA MA28600A patent/MA27804A1/fr unknown
- 2005-11-17 NO NO20055443A patent/NO20055443L/no not_active Application Discontinuation
2010
- 2010-04-30 US US12/771,557 patent/US8029811B2/en not_active Expired - Lifetime
2011
- 2011-08-26 US US13/219,046 patent/US8163299B2/en not_active Expired - Lifetime
2012
- 2012-04-02 US US13/437,569 patent/US8440210B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
GB0312148D0 (en)	2003-07-02
ZA200509099B (en)	2006-08-30
US20120247982A1 (en)	2012-10-04
JP5175048B2 (ja)	2013-04-03
RU2005136869A (ru)	2006-06-10
RU2337667C2 (ru)	2008-11-10
US20100247585A1 (en)	2010-09-30
AU2004243223A1 (en)	2004-12-09
CA2527088C (en)	2011-03-01
MXPA05012757A (es)	2006-02-13
PL1626913T3 (pl)	2010-07-30
US20060147537A1 (en)	2006-07-06
US20110308975A1 (en)	2011-12-22
US8163299B2 (en)	2012-04-24
US7736673B2 (en)	2010-06-15
DE602004025463D1 (de)	2010-03-25
JP2007504277A (ja)	2007-03-01
NO20055443L (no)	2005-11-17
BRPI0410701A (pt)	2006-06-13
RS20050882A (sr)	2007-12-31
US8440210B2 (en)	2013-05-14
ES2340681T3 (es)	2010-06-08
WO2004105727A2 (en)	2004-12-09
WO2004105727A3 (en)	2005-06-16
TW200509989A (en)	2005-03-16
KR20060023539A (ko)	2006-03-14
CA2527088A1 (en)	2004-12-09
CN1832890A (zh)	2006-09-13
EP1626913A2 (de)	2006-02-22
AR047619A1 (es)	2006-02-01
EP1626913B1 (de)	2010-02-10
MA27804A1 (fr)	2006-03-01
US8029811B2 (en)	2011-10-04

Legal Events

Date	Code	Title	Description
2010-08-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE457163T1 (de)	2010-02-15	Verwendung von ciclesonide zur erhaltung des feinen teilchengrössenanteils von formoterol
ATE465712T1 (de)	2010-05-15	Ultrafeine zusammensetzungen von formoterol
DE602004012969D1 (de)	2008-05-21	Phenylacetamide und ihre verwendung als glukokinase-modulatoren
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