ATE457981T1 - 3-amido-1,2-benzisoxazolderivate, herstellungsverfahren und deren verwendung - Google Patents

3-amido-1,2-benzisoxazolderivate, herstellungsverfahren und deren verwendung

Info

Publication number
ATE457981T1
ATE457981T1 AT02782007T AT02782007T ATE457981T1 AT E457981 T1 ATE457981 T1 AT E457981T1 AT 02782007 T AT02782007 T AT 02782007T AT 02782007 T AT02782007 T AT 02782007T AT E457981 T1 ATE457981 T1 AT E457981T1
Authority
AT
Austria
Prior art keywords
amido
production process
relates
benzoisoxazole
present
Prior art date
Application number
AT02782007T
Other languages
English (en)
Inventor
Jin-Soo Lee
Seok-Hoon Ahn
Young-Goo Jin
Sang-Mi Jin
Sae-Kwang Ku
Jei-Man Rye
Yong-Ho Chung
Eun-Joo Kim
Sun-Ki Cho
Original Assignee
Dong Wha Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong Wha Pharm Co Ltd filed Critical Dong Wha Pharm Co Ltd
Application granted granted Critical
Publication of ATE457981T1 publication Critical patent/ATE457981T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02782007T 2001-11-06 2002-11-05 3-amido-1,2-benzisoxazolderivate, herstellungsverfahren und deren verwendung ATE457981T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020010069013A KR100789567B1 (ko) 2001-11-06 2001-11-06 3-아미도-1,2-벤조이소옥사졸 유도체, 그 염, 제조방법 및 용도
PCT/KR2002/002058 WO2003040113A1 (en) 2001-11-06 2002-11-05 3-amido-1,2-benzoisoxazole derivatives, process for preparation, and use thereof

Publications (1)

Publication Number Publication Date
ATE457981T1 true ATE457981T1 (de) 2010-03-15

Family

ID=19715763

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02782007T ATE457981T1 (de) 2001-11-06 2002-11-05 3-amido-1,2-benzisoxazolderivate, herstellungsverfahren und deren verwendung

Country Status (9)

Country Link
US (1) US7291638B2 (de)
EP (1) EP1451163B1 (de)
JP (1) JP2005508987A (de)
KR (1) KR100789567B1 (de)
CN (1) CN1309711C (de)
AT (1) ATE457981T1 (de)
DE (1) DE60235396D1 (de)
ES (1) ES2338102T3 (de)
WO (1) WO2003040113A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2361867C2 (ru) * 2004-11-23 2009-07-20 Донг Вха Фармасьютикал. Инд. Ко., Лтд. Диметансульфонат n-гидрокси-4{5-[4-(5-изопропил-2-метил-1, 3-тиазол-4-ил)фенокси]пентокси}бензамидина
DE102005038947A1 (de) 2005-05-18 2006-11-30 Grünenthal GmbH Substituierte Benzo[d]isoxazol-3-yl-amin-Verbindungen und deren Verwendung in Arzneimitteln
DE102005026194A1 (de) * 2005-06-06 2006-12-07 Grünenthal GmbH Substituierte N-Benzo[d]isoxazol-3-yl-amin-Derivate und deren Verwendung zur Herstellung von Arzneimitteln
AU2006279325B2 (en) * 2005-08-18 2013-06-27 Accelalox, Inc. Methods for bone treatment by modulating an arachidonic acid metabolic or signaling pathway
JP2009508596A (ja) 2005-09-19 2009-03-05 ヒストジェニックス コーポレイション 細胞支持基材及びその調製方法
WO2009105723A2 (en) * 2008-02-22 2009-08-27 Accelalox, Inc. Novel methods for bone treatment by modulating an arachidonic acid metabolic or signaling pathway
JP6014155B2 (ja) 2011-10-31 2016-10-25 ゼノン・ファーマシューティカルズ・インコーポレイテッドＸｅｎｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． ビアリールエーテルスルホンアミドおよび治療剤としてのそれらの使用
US9630929B2 (en) 2011-10-31 2017-04-25 Xenon Pharmaceuticals Inc. Benzenesulfonamide compounds and their use as therapeutic agents
SG11201408284VA (en) 2012-05-22 2015-02-27 Xenon Pharmaceuticals Inc N-substituted benzamides and their use in the treatment of pain
US10071957B2 (en) 2012-07-06 2018-09-11 Genentech, Inc. N-substituted benzamides and methods of use thereof
US9550775B2 (en) 2013-03-14 2017-01-24 Genentech, Inc. Substituted triazolopyridines and methods of use thereof
CN105492430B (zh) * 2013-03-15 2017-10-10 基因泰克公司 取代的苯并噁唑及其使用方法
MX2015010775A (es) 2013-03-15 2016-04-25 Genentech Inc Benzoxazoles sustituidos y metodos para usarlos.
CR20160296A (es) 2013-11-27 2016-09-20 Genentech Inc Benzamidas sustituidas y métodos para usarlas
CN106715418A (zh) 2014-07-07 2017-05-24 基因泰克公司 治疗化合物及其使用方法
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
JP2018520107A (ja) 2015-05-22 2018-07-26 ジェネンテック， インコーポレイテッド 置換ベンズアミド及びその使用方法
EP3341353A1 (de) 2015-08-27 2018-07-04 Genentech, Inc. Therapeutische verbindungen und verfahren zur verwendung davon
CN108290881B (zh) 2015-09-28 2021-12-07 健泰科生物技术公司 治疗性化合物和其使用方法
US10899732B2 (en) 2015-11-25 2021-01-26 Genentech, Inc. Substituted benzamides useful as sodium channel blockers
EP3854782A1 (de) 2016-03-30 2021-07-28 Genentech, Inc. Substituierte benzamide und verfahren zur verwendung davon
CA3035907A1 (en) * 2016-09-09 2018-03-15 Walmart Apollo, Llc Apparatus and method for monitoring a field
AU2017347549A1 (en) 2016-10-17 2019-05-02 Genentech, Inc. Therapeutic compounds and methods of use thereof
JP2020511511A (ja) 2017-03-24 2020-04-16 ジェネンテック， インコーポレイテッド ナトリウムチャネル阻害剤としての４−ピペリジン−ｎ−（ピリミジン−４−イル）クロマン−７−スルホンアミド誘導体
AR114263A1 (es) 2018-02-26 2020-08-12 Genentech Inc Compuestos terapéuticos y métodos para utilizarlos
WO2019191702A1 (en) 2018-03-30 2019-10-03 F. Hoffmann-La Roche Ag Substituted hydro-pyrido-azines as sodium channel inhibitors
TW202003490A (zh) 2018-05-22 2020-01-16 瑞士商赫孚孟拉羅股份公司 治療性化合物及其使用方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2737213B2 (ja) * 1989-03-10 1998-04-08 日産化学工業株式会社 ロイコトリエンｂ▲下４▼誘導体
CA2146755A1 (en) * 1992-10-28 1994-05-11 Kenji Takeda Novel 1,2-benzoisoxazole derivative or its salt and brain-protecting agent comprising the same
CN1074923C (zh) * 1993-11-19 2001-11-21 詹森药业有限公司 微囊密封的3-哌啶基取代的1,2-苯并异唑类和1,2-苯并异噻唑类
US6150390A (en) * 1997-02-04 2000-11-21 Dong Wha Pharm. Ind. Co., Ltd. 3-amino-1,2-benzoisoxazole derivatives, process for preparation, and use thereof

Also Published As

Publication number Publication date
US7291638B2 (en) 2007-11-06
CN1578775A (zh) 2005-02-09
EP1451163A1 (de) 2004-09-01
DE60235396D1 (de) 2010-04-01
US20050020650A1 (en) 2005-01-27
JP2005508987A (ja) 2005-04-07
WO2003040113A1 (en) 2003-05-15
EP1451163A4 (de) 2005-01-26
KR100789567B1 (ko) 2007-12-28
ES2338102T3 (es) 2010-05-04
CN1309711C (zh) 2007-04-11
KR20030038868A (ko) 2003-05-17
EP1451163B1 (de) 2010-02-17

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