ATE457981T1 - 3-amido-1,2-benzisoxazolderivate, herstellungsverfahren und deren verwendung - Google Patents

3-amido-1,2-benzisoxazolderivate, herstellungsverfahren und deren verwendung

Info

Publication number
ATE457981T1
ATE457981T1 AT02782007T AT02782007T ATE457981T1 AT E457981 T1 ATE457981 T1 AT E457981T1 AT 02782007 T AT02782007 T AT 02782007T AT 02782007 T AT02782007 T AT 02782007T AT E457981 T1 ATE457981 T1 AT E457981T1
Authority
AT
Austria
Prior art keywords
amido
production process
relates
benzoisoxazole
present
Prior art date
Application number
AT02782007T
Other languages
English (en)
Inventor
Jin-Soo Lee
Seok-Hoon Ahn
Young-Goo Jin
Sang-Mi Jin
Sae-Kwang Ku
Jei-Man Rye
Yong-Ho Chung
Eun-Joo Kim
Sun-Ki Cho
Original Assignee
Dong Wha Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong Wha Pharm Co Ltd filed Critical Dong Wha Pharm Co Ltd
Application granted granted Critical
Publication of ATE457981T1 publication Critical patent/ATE457981T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02782007T 2001-11-06 2002-11-05 3-amido-1,2-benzisoxazolderivate, herstellungsverfahren und deren verwendung ATE457981T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020010069013A KR100789567B1 (ko) 2001-11-06 2001-11-06 3-아미도-1,2-벤조이소옥사졸 유도체, 그 염, 제조방법 및 용도
PCT/KR2002/002058 WO2003040113A1 (en) 2001-11-06 2002-11-05 3-amido-1,2-benzoisoxazole derivatives, process for preparation, and use thereof

Publications (1)

Publication Number Publication Date
ATE457981T1 true ATE457981T1 (de) 2010-03-15

Family

ID=19715763

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02782007T ATE457981T1 (de) 2001-11-06 2002-11-05 3-amido-1,2-benzisoxazolderivate, herstellungsverfahren und deren verwendung

Country Status (9)

Country Link
US (1) US7291638B2 (de)
EP (1) EP1451163B1 (de)
JP (1) JP2005508987A (de)
KR (1) KR100789567B1 (de)
CN (1) CN1309711C (de)
AT (1) ATE457981T1 (de)
DE (1) DE60235396D1 (de)
ES (1) ES2338102T3 (de)
WO (1) WO2003040113A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1701722E (pt) * 2004-11-23 2009-12-10 Dong Wha Pharm Co Ltd Sal do ácido n-hidroxi-4-{5-[4-(5-isopropil-2-metil-1,3-tiazol- 4-il)fenoxi]pentoxi}benzamidina-2-metanossulfónico
DE102005038947A1 (de) * 2005-05-18 2006-11-30 Grünenthal GmbH Substituierte Benzo[d]isoxazol-3-yl-amin-Verbindungen und deren Verwendung in Arzneimitteln
DE102005026194A1 (de) * 2005-06-06 2006-12-07 Grünenthal GmbH Substituierte N-Benzo[d]isoxazol-3-yl-amin-Derivate und deren Verwendung zur Herstellung von Arzneimitteln
EP1947942B1 (de) * 2005-08-18 2015-07-29 Accelalox, Inc. Verfahren zur behandlung von knochen durch modulation eines arachidonsäure-stoffwechsel- oder -signalleitungswegs
CA2623106C (en) 2005-09-19 2013-12-24 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
WO2009105723A2 (en) * 2008-02-22 2009-08-27 Accelalox, Inc. Novel methods for bone treatment by modulating an arachidonic acid metabolic or signaling pathway
ES2586213T3 (es) 2011-10-31 2016-10-13 Xenon Pharmaceuticals Inc. Compuestos de bencenosulfonamida y su uso como agentes terapéuticos
JP6014155B2 (ja) 2011-10-31 2016-10-25 ゼノン・ファーマシューティカルズ・インコーポレイテッドＸｅｎｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． ビアリールエーテルスルホンアミドおよび治療剤としてのそれらの使用
BR112014029161A2 (pt) 2012-05-22 2017-06-27 Genentech Inc benzamidas n-substituídas e seu uso no tratamento de dor
BR112015000187A2 (pt) 2012-07-06 2017-06-27 Genentech Inc benzamidas substituídas com n e métodos de uso das mesmas
BR112015022488A2 (pt) 2013-03-14 2017-07-18 Genentech Inc triazolopiridinas substituídas e métodos de uso das mesmas
BR112015023397A2 (pt) 2013-03-15 2017-07-18 Genentech Inc benzoxazois substituídos e métodos de uso dos mesmos
CN105492430B (zh) * 2013-03-15 2017-10-10 基因泰克公司 取代的苯并噁唑及其使用方法
CR20160296A (es) 2013-11-27 2016-09-20 Genentech Inc Benzamidas sustituidas y métodos para usarlas
EP3166939B1 (de) 2014-07-07 2019-06-05 Genentech, Inc. Therapeutische verbindungen und verfahren zur verwendung davon
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
WO2016191312A1 (en) 2015-05-22 2016-12-01 Genentech, Inc. Substituted benzamides and methods of use thereof
MA42683A (fr) 2015-08-27 2018-07-04 Genentech Inc Composés thérapeutiques et leurs méthodes utilisation
PE20181003A1 (es) 2015-09-28 2018-06-26 Genentech Inc Compuestos terapeuticos y sus metodos de uso
CN108495851A (zh) 2015-11-25 2018-09-04 基因泰克公司 取代的苯甲酰胺及其使用方法
EP3854782A1 (de) 2016-03-30 2021-07-28 Genentech, Inc. Substituierte benzamide und verfahren zur verwendung davon
CN109997116A (zh) * 2016-09-09 2019-07-09 沃尔玛阿波罗有限责任公司 用于监视现场的装置和方法
SG11201903348UA (en) 2016-10-17 2019-05-30 Genentech Inc Therapeutic compounds and methods of use thereof
WO2018175707A1 (en) 2017-03-24 2018-09-27 Genentech, Inc. 4-piperidin-n-(pyrimidin-4-yl)chroman-7-sulfonamide derivatives as sodium channel inhibitors
EP3759098A1 (de) 2018-02-26 2021-01-06 Genentech, Inc. Pyridinsulfonamidverbindungen und deren verwendung gegen schmerz und verwandte störungen
EP3774801A1 (de) 2018-03-30 2021-02-17 F. Hoffmann-La Roche AG Hydro-pyrido-verbindungen mit kondensierten ringen als natriumkanalinhibitoren
TW202003490A (zh) 2018-05-22 2020-01-16 瑞士商赫孚孟拉羅股份公司 治療性化合物及其使用方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2737213B2 (ja) * 1989-03-10 1998-04-08 日産化学工業株式会社 ロイコトリエンｂ▲下４▼誘導体
WO1994010158A1 (fr) * 1992-10-28 1994-05-11 Toyama Chemical Co., Ltd. Nouveaux derives de 1,2-benzisoxazole ou sel dudit derive, et agent de protection cerebrale contenant ce derive
ATE288270T1 (de) * 1993-11-19 2005-02-15 Janssen Pharmaceutica Nv Mikroverkapselte 1,2-benzazole
WO1998033779A1 (en) * 1997-02-04 1998-08-06 Dong Wha Pharm. Ind. Co., Ltd. 3-amino-1,2-benzoisoxazole derivatives, process for preparation, and use thereof

Also Published As

Publication number Publication date
CN1578775A (zh) 2005-02-09
US20050020650A1 (en) 2005-01-27
EP1451163A1 (de) 2004-09-01
WO2003040113A1 (en) 2003-05-15
EP1451163B1 (de) 2010-02-17
EP1451163A4 (de) 2005-01-26
US7291638B2 (en) 2007-11-06
KR100789567B1 (ko) 2007-12-28
KR20030038868A (ko) 2003-05-17
JP2005508987A (ja) 2005-04-07
DE60235396D1 (de) 2010-04-01
ES2338102T3 (es) 2010-05-04
CN1309711C (zh) 2007-04-11

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