ATE458493T1 - Immunogene lhrh zusammensetzungen sowie damit zusammenhängende verfahren - Google Patents

Immunogene lhrh zusammensetzungen sowie damit zusammenhängende verfahren

Info

Publication number: ATE458493T1
Authority: AT; Austria
Prior art keywords: related methods; immunogenic lhrh; lhrh compositions; immunogenic; compositions
Prior art date: 1997-07-09

Application number

AT98931835T

Other languages

English (en)

Inventor

Michael Mcnamara

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-07-09

Filing date

1998-07-09

Publication date

2010-03-15

1998-07-09 Application filed by Pfizer filed Critical Pfizer

2010-03-15 Application granted granted Critical

2010-03-15 Publication of ATE458493T1 publication Critical patent/ATE458493T1/de

Links

101000904173 Homo sapiens Progonadoliberin-1 Proteins 0.000 title abstract 2
102100024028 Progonadoliberin-1 Human genes 0.000 title abstract 2
101000996723 Sus scrofa Gonadotropin-releasing hormone receptor Proteins 0.000 title abstract 2
XLXSAKCOAKORKW-UHFFFAOYSA-N gonadorelin Chemical compound C1CCC(C(=O)NCC(N)=O)N1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(CO)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C(CC=1NC=NC=1)NC(=O)C1NC(=O)CC1)CC1=CC=C(O)C=C1 XLXSAKCOAKORKW-UHFFFAOYSA-N 0.000 title abstract 2
230000002163 immunogen Effects 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
241000282887 Suidae Species 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
230000003247 decreasing effect Effects 0.000 abstract 1
230000002130 immunocastration Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0006—Contraceptive vaccins; Vaccines against sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55583—Polysaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Virology (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Diabetes (AREA)
Mycology (AREA)
Gastroenterology & Hepatology (AREA)
Gynecology & Obstetrics (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Pregnancy & Childbirth (AREA)
Neurology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)

AT98931835T 1997-07-09 1998-07-09 Immunogene lhrh zusammensetzungen sowie damit zusammenhängende verfahren ATE458493T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
AUPO7768A AUPO776897A0 (en)	1997-07-09	1997-07-09	A method of achieving production gains in livestock and agents useful for same
PCT/AU1998/000532 WO1999002180A1 (en)	1997-07-09	1998-07-09	Immunogenic lhrh compositions and methods relating thereto

Publications (1)

Publication Number	Publication Date
ATE458493T1 true ATE458493T1 (de)	2010-03-15

Family

ID=3802056

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98931835T ATE458493T1 (de)	1997-07-09	1998-07-09	Immunogene lhrh zusammensetzungen sowie damit zusammenhängende verfahren

Country Status (19)

Country	Link
US (6)	US7534441B2 (de)
EP (4)	EP1007084B1 (de)
JP (3)	JP5116916B2 (de)
KR (2)	KR20060101554A (de)
AT (1)	ATE458493T1 (de)
AU (2)	AUPO776897A0 (de)
CA (1)	CA2294865C (de)
CY (2)	CY1109968T1 (de)
DE (2)	DE122010000033I1 (de)
DK (1)	DK1007084T3 (de)
ES (1)	ES2339308T3 (de)
FR (2)	FR10C0035I2 (de)
LU (1)	LU91711I2 (de)
NZ (1)	NZ502080A (de)
PL (1)	PL200495B1 (de)
PT (1)	PT1007084E (de)
TW (1)	TWI235666B (de)
WO (1)	WO1999002180A1 (de)
ZA (1)	ZA986074B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AUPO776897A0 (en) *	1997-07-09	1997-07-31	Csl Limited	A method of achieving production gains in livestock and agents useful for same
AUPP807399A0 (en) *	1999-01-08	1999-02-04	Csl Limited	Improved immunogenic lhrh composition and methods relating thereto
ATE286511T1 (de)	1999-02-17	2005-01-15	Pfizer Prod Inc	Fusionsproteine mit trägern welche eine doppelte immunantwort induzieren
US8088734B2 (en) *	2003-01-21	2012-01-03	Unigene Laboratories Inc.	Oral delivery of peptides
US20090028886A1 (en) *	2004-08-04	2009-01-29	Cytos Biotechnology Ag	Carrier conjugates of gnrh-peptides
EP1890725A2 (de) *	2005-06-01	2008-02-27	Pfizer Products Inc.	Impfstoffzusammensetzungen und verfahren zur behandlung von harninkontinenz
WO2008110912A1 (en) *	2007-03-14	2008-09-18	Pfizer Inc.	Fertility regulation in horses
MY176727A (en)	2012-12-03	2020-08-20	Pfizer	Selective androgen receptor modulators
KR101918381B1 (ko) *	2017-01-11	2018-11-13	이경민	칠보 공예품을 제조하는 방법과 이에 의하여 제조되는 칠보 공예품
KR102477054B1 (ko) *	2020-03-24	2022-12-14	주식회사 바이오앱	웅취 제거용 재조합 단백질 및 이를 포함하는 백신 조성물
AU2024296166A1 (en) *	2023-07-07	2025-09-25	Ouro Fino Saúde Animal Ltda	Modified gnrh peptide and its conjugate for mammalian immunocastration, manufacturing method, composition and kit

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3963691A (en) *	1974-10-07	1976-06-15	Merck & Co., Inc.	Synthetic antigens of luteinizing hormone releasing hormone
DE3411224A1 (de) *	1984-03-27	1985-10-10	Hoechst Ag, 6230 Frankfurt	Verfahren zur racematarmen herstellung von peptidzwischenprodukten der gonadorelin- und gonadorelinanaloga-synthese und neue zwischenprodukte bei diesem verfahren
NZ220932A (en) *	1986-07-03	1990-05-28	Victoria State	Composition comprising an antigenic substance, such as lhrh, conjugated to at least two different carriers and method of immunological castration and spaying
NZ221306A (en)	1986-08-15	1990-02-26	Commw Scient Ind Res Org	2-component immunoadjuvant comprising a mycobacterial free immunoadjuvant oil and a polycationic polyelectrolyte immunoadjuvant and vaccines thereof
WO1988005308A1 (en) *	1987-01-14	1988-07-28	Commonwealth Scientific And Industrial Research Or	Anti reproductive hormone
GB2228262B (en) *	1989-01-25	1992-10-07	Nat Inst Immunology	Antigenic derivative of gnrh
WO1990009799A1 (en) *	1989-02-23	1990-09-07	Colorado State University Research Foundation	GnRH ANALOGS FOR DESTROYING GONADOTROPHS
NL8900726A (nl)	1989-03-23	1990-10-16	Stichting Centr Diergeneeskund	Peptide, immunogene samenstelling en vaccin- of geneesmiddelpreparaat; werkwijze voor het immuniseren van een zoogdier tegen lhrh, en werkwijze voor het verbeteren van de vleeskwaliteit van varkens.
US5138034A (en) *	1989-07-12	1992-08-11	The Green Cross Corporation	Method of fractionating plasma proteins
ATE140972T1 (de)	1989-08-25	1996-08-15	Biotech Australia Pty Ltd	Fusionsproteine bestehend aus tratp und mindestens einem lhrh-analog
US5324512A (en)	1990-12-26	1994-06-28	The Population Council	[Gln']-luteinizing hormone releasing hormone conjugate of tetanus vaccine and its uses
ES2149166T3 (es) *	1991-03-01	2000-11-01	Merial Sas	Procedimiento de inmunoneutralizacion anti-lhrm de los animales domesticos machos no castrados y peptido para su realizacion.
EP0596959B1 (de) *	1991-07-26	2000-03-29	Commonwealth Scientific And Industrial Research Organisation	System der bereitstellung eines impfstoffes auf peptidbasis, das sein eigenes adjuvans bildet, und seine herstellung
US5837268A (en)	1991-10-16	1998-11-17	University Of Saskatchewan	GnRH-leukotoxin chimeras
ZA934199B (en)	1992-06-18	1994-01-10	Akzo Nv	Carrier system against gnrh
US5614487A (en)	1993-05-28	1997-03-25	Genentech, Inc.	Sustained release pharmaceutical composition
US5688506A (en) *	1994-01-27	1997-11-18	Aphton Corp.	Immunogens against gonadotropin releasing hormone
US5885966A (en) *	1995-06-07	1999-03-23	Dlo Instituut Voor Dierhouderij En Diergezondheid	Peptide, immunogenic composition and vaccine or medical preparation, a method to immunise animals against the hormone LHRH, and analogs of the LHRH tandem repeat peptide and their use as vaccine
WO1996040755A1 (en)	1995-06-07	1996-12-19	Dlo Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo)	An improved peptide, immunogenic composition and vaccine or medical preparation, a method to immunise animals against the hormone lhrh, and analogs of the lhrh tandem repeat peptide and their use as vaccine
WO1997015316A1 (en)	1995-10-27	1997-05-01	Merck & Co., Inc.	Conjugates of gonadotropin releasing hormone
AUPO776897A0 (en) *	1997-07-09	1997-07-31	Csl Limited	A method of achieving production gains in livestock and agents useful for same
US6013770A (en)	1997-07-21	2000-01-11	Washington State University	Chimeric contraceptive vaccines

1997
- 1997-07-09 AU AUPO7768A patent/AUPO776897A0/en not_active Abandoned
1998
- 1998-07-09 PT PT98931835T patent/PT1007084E/pt unknown
- 1998-07-09 EP EP98931835A patent/EP1007084B1/de not_active Expired - Lifetime
- 1998-07-09 WO PCT/AU1998/000532 patent/WO1999002180A1/en not_active Ceased
- 1998-07-09 PL PL338037A patent/PL200495B1/pl unknown
- 1998-07-09 DE DE201012000033 patent/DE122010000033I1/de active Pending
- 1998-07-09 EP EP10154395A patent/EP2196213A1/de not_active Withdrawn
- 1998-07-09 EP EP10184161A patent/EP2316477A1/de not_active Withdrawn
- 1998-07-09 DK DK98931835.7T patent/DK1007084T3/da active
- 1998-07-09 DE DE69841521T patent/DE69841521D1/de not_active Expired - Lifetime
- 1998-07-09 AU AU82001/98A patent/AU725562B2/en not_active Expired
- 1998-07-09 AT AT98931835T patent/ATE458493T1/de active
- 1998-07-09 TW TW087111118A patent/TWI235666B/zh not_active IP Right Cessation
- 1998-07-09 ES ES98931835T patent/ES2339308T3/es not_active Expired - Lifetime
- 1998-07-09 NZ NZ502080A patent/NZ502080A/en not_active IP Right Cessation
- 1998-07-09 EP EP10154397A patent/EP2191839A3/de not_active Withdrawn
- 1998-07-09 KR KR1020067015504A patent/KR20060101554A/ko not_active Ceased
- 1998-07-09 KR KR1020007000181A patent/KR100680631B1/ko not_active Expired - Lifetime
- 1998-07-09 CA CA2294865A patent/CA2294865C/en not_active Expired - Lifetime
- 1998-07-09 JP JP2000501770A patent/JP5116916B2/ja not_active Expired - Lifetime
- 1998-09-07 ZA ZA986074A patent/ZA986074B/xx unknown
2005
- 2005-01-03 US US11/027,683 patent/US7534441B2/en not_active Expired - Fee Related
2009
- 2009-04-02 US US12/384,242 patent/US20090226484A1/en not_active Abandoned
- 2009-04-09 US US12/384,974 patent/US20090291098A1/en not_active Abandoned
- 2009-10-23 JP JP2009244560A patent/JP5231378B2/ja not_active Expired - Lifetime
2010
- 2010-04-13 CY CY20101100331T patent/CY1109968T1/el unknown
- 2010-07-07 CY CY2010013C patent/CY2010013I2/el unknown
- 2010-07-09 FR FR10C0035C patent/FR10C0035I2/fr active Active
- 2010-07-28 LU LU91711C patent/LU91711I2/fr unknown
- 2010-08-24 FR FR10C0040C patent/FR10C0040I1/fr active Active
2011
- 2011-06-23 US US13/167,438 patent/US20110293647A1/en not_active Abandoned
2012
- 2012-08-16 US US13/587,249 patent/US8741303B2/en not_active Expired - Fee Related
- 2012-09-05 JP JP2012195610A patent/JP2013006862A/ja active Pending
2014
- 2014-04-18 US US14/256,043 patent/US20140271695A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DE69841521D1 (de)	2010-04-08
KR20010021623A (ko)	2001-03-15
US20060024290A1 (en)	2006-02-02
US20090226484A1 (en)	2009-09-10
ZA986074B (en)	1999-03-16
EP2196213A1 (de)	2010-06-16
JP2010059167A (ja)	2010-03-18
FR10C0035I2 (fr)	2012-06-22
CY2010013I1 (el)	2012-01-25
EP1007084A4 (de)	2003-07-02
WO1999002180A1 (en)	1999-01-21
CY1109968T1 (el)	2012-01-25
AU8200198A (en)	1999-02-08
ES2339308T3 (es)	2010-05-18
DE122010000033I1 (de)	2011-12-01
TWI235666B (en)	2005-07-11
JP2013006862A (ja)	2013-01-10
NZ502080A (en)	2001-09-28
EP1007084B1 (de)	2010-02-24
JP5231378B2 (ja)	2013-07-10
AU725562B2 (en)	2000-10-12
JP5116916B2 (ja)	2013-01-09
US20120328639A1 (en)	2012-12-27
FR10C0035I1 (fr)	2010-08-27
PL338037A1 (en)	2000-09-25
CY2010013I2 (el)	2012-01-25
US7534441B2 (en)	2009-05-19
US8741303B2 (en)	2014-06-03
AUPO776897A0 (en)	1997-07-31
PL200495B1 (pl)	2009-01-30
EP1007084A1 (de)	2000-06-14
EP2191839A3 (de)	2010-09-08
PT1007084E (pt)	2010-04-08
EP2191839A2 (de)	2010-06-02
US20090291098A1 (en)	2009-11-26
CA2294865C (en)	2013-05-21
EP2316477A1 (de)	2011-05-04
KR20060101554A (ko)	2006-09-25
DK1007084T3 (da)	2010-05-03
KR100680631B1 (ko)	2007-02-09
FR10C0040I1 (fr)	2010-10-15
US20140271695A1 (en)	2014-09-18
JP2001509489A (ja)	2001-07-24
CA2294865A1 (en)	1999-01-21
LU91711I2 (fr)	2010-09-28
US20110293647A1 (en)	2011-12-01

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