ATE458534T1 - Medizinische vorrichtung zur gesteuerten arzneimittelverabreichung sowie herzüberwachung und/oder herzstimulation - Google Patents
Medizinische vorrichtung zur gesteuerten arzneimittelverabreichung sowie herzüberwachung und/oder herzstimulationInfo
- Publication number
- ATE458534T1 ATE458534T1 AT03773170T AT03773170T ATE458534T1 AT E458534 T1 ATE458534 T1 AT E458534T1 AT 03773170 T AT03773170 T AT 03773170T AT 03773170 T AT03773170 T AT 03773170T AT E458534 T1 ATE458534 T1 AT E458534T1
- Authority
- AT
- Austria
- Prior art keywords
- medical device
- cardiac
- patient
- drug
- drug delivery
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic using feedback of body parameters, e.g. blood sugar or pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/3629—Heart stimulators in combination with non-electric therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0244—Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/35—Communication
- A61M2205/3507—Communication with implanted devices, e.g. external control
- A61M2205/3523—Communication with implanted devices, e.g. external control using telemetric means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/04—Heartbeat characteristics, e.g. ECG, blood pressure modulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
- A61M5/16804—Active flow controllers
- A61M5/16827—Active flow controllers controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
- A61N1/39—Heart defibrillators
- A61N1/3956—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Diabetes (AREA)
- Electrotherapy Devices (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41600502P | 2002-10-04 | 2002-10-04 | |
| US44455403P | 2003-02-03 | 2003-02-03 | |
| US46016303P | 2003-04-03 | 2003-04-03 | |
| PCT/US2003/031596 WO2004033036A2 (en) | 2002-10-04 | 2003-10-06 | Medical device for controlled drug delivery and cardiac monitoring and/or stimulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE458534T1 true ATE458534T1 (de) | 2010-03-15 |
Family
ID=32096880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03773170T ATE458534T1 (de) | 2002-10-04 | 2003-10-06 | Medizinische vorrichtung zur gesteuerten arzneimittelverabreichung sowie herzüberwachung und/oder herzstimulation |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7917208B2 (de) |
| EP (1) | EP1551505B1 (de) |
| AT (1) | ATE458534T1 (de) |
| AU (1) | AU2003279842A1 (de) |
| DE (1) | DE60331455D1 (de) |
| WO (1) | WO2004033036A2 (de) |
Families Citing this family (169)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6302875B1 (en) | 1996-10-11 | 2001-10-16 | Transvascular, Inc. | Catheters and related devices for forming passageways between blood vessels or other anatomical structures |
| WO2001012157A1 (en) * | 1999-08-18 | 2001-02-22 | Microchips, Inc. | Thermally-activated microchip chemical delivery devices |
| ATE323470T1 (de) * | 1999-12-10 | 2006-05-15 | Massachusetts Inst Technology | Mikrochip-arzneistoffverabreichungssysteme und herstellungsverfahren |
| ES2420279T3 (es) | 2000-03-02 | 2013-08-23 | Microchips, Inc. | Dispositivos microfabricados y métodos para almacenamiento y exposición selectiva de productos químicos |
| EP1339312B1 (de) * | 2000-10-10 | 2006-01-04 | Microchips, Inc. | Mikrochip-reservoir-vorrichtungen mit drahtloser übertragung von energie und daten |
| DE60219607T2 (de) | 2001-01-09 | 2007-12-27 | Microchips, Inc., Bedford | Flexible mikrochip-vorrichtungen zur ophthalmologischen und anderen applikation |
| US6875208B2 (en) * | 2001-05-31 | 2005-04-05 | Massachusetts Institute Of Technology | Microchip devices with improved reservoir opening |
| WO2003032957A2 (en) * | 2001-06-28 | 2003-04-24 | Microchips, Inc. | Methods for hermetically sealing microchip reservoir devices |
| US8145316B2 (en) | 2002-04-08 | 2012-03-27 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
| US8774922B2 (en) | 2002-04-08 | 2014-07-08 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods |
| US7162303B2 (en) | 2002-04-08 | 2007-01-09 | Ardian, Inc. | Renal nerve stimulation method and apparatus for treatment of patients |
| US8145317B2 (en) | 2002-04-08 | 2012-03-27 | Ardian, Inc. | Methods for renal neuromodulation |
| US9308043B2 (en) | 2002-04-08 | 2016-04-12 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for monopolar renal neuromodulation |
| US6978174B2 (en) | 2002-04-08 | 2005-12-20 | Ardian, Inc. | Methods and devices for renal nerve blocking |
| US8150519B2 (en) | 2002-04-08 | 2012-04-03 | Ardian, Inc. | Methods and apparatus for bilateral renal neuromodulation |
| US7653438B2 (en) | 2002-04-08 | 2010-01-26 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
| US9636174B2 (en) | 2002-04-08 | 2017-05-02 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for therapeutic renal neuromodulation |
| US8131371B2 (en) | 2002-04-08 | 2012-03-06 | Ardian, Inc. | Methods and apparatus for monopolar renal neuromodulation |
| US20070135875A1 (en) | 2002-04-08 | 2007-06-14 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
| US20080213331A1 (en) | 2002-04-08 | 2008-09-04 | Ardian, Inc. | Methods and devices for renal nerve blocking |
| US9308044B2 (en) | 2002-04-08 | 2016-04-12 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for therapeutic renal neuromodulation |
| US8347891B2 (en) | 2002-04-08 | 2013-01-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen |
| US8774913B2 (en) | 2002-04-08 | 2014-07-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for intravasculary-induced neuromodulation |
| US7756583B2 (en) | 2002-04-08 | 2010-07-13 | Ardian, Inc. | Methods and apparatus for intravascularly-induced neuromodulation |
| US20070129761A1 (en) | 2002-04-08 | 2007-06-07 | Ardian, Inc. | Methods for treating heart arrhythmia |
| US7853333B2 (en) | 2002-04-08 | 2010-12-14 | Ardian, Inc. | Methods and apparatus for multi-vessel renal neuromodulation |
| US20140018880A1 (en) | 2002-04-08 | 2014-01-16 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for monopolar renal neuromodulation |
| US7617005B2 (en) | 2002-04-08 | 2009-11-10 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
| US8175711B2 (en) | 2002-04-08 | 2012-05-08 | Ardian, Inc. | Methods for treating a condition or disease associated with cardio-renal function |
| US7620451B2 (en) | 2005-12-29 | 2009-11-17 | Ardian, Inc. | Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach |
| AU2003303288B2 (en) * | 2002-08-16 | 2006-12-07 | Microchips, Inc. | Controlled release device and method |
| WO2004022033A1 (en) * | 2002-09-04 | 2004-03-18 | Microchips, Inc. | Method and device for the controlled delivery of parathyroid hormone |
| US8303511B2 (en) * | 2002-09-26 | 2012-11-06 | Pacesetter, Inc. | Implantable pressure transducer system optimized for reduced thrombosis effect |
| US20040247671A1 (en) * | 2003-04-25 | 2004-12-09 | Prescott James H. | Solid drug formulation and device for storage and controlled delivery thereof |
| WO2005010240A2 (en) * | 2003-07-17 | 2005-02-03 | Microchips, Inc. | Low temperature methods for hermetically sealing reservoir devices |
| US20050055014A1 (en) * | 2003-08-04 | 2005-03-10 | Coppeta Jonathan R. | Methods for accelerated release of material from a reservoir device |
| US7392084B2 (en) | 2003-09-23 | 2008-06-24 | Cardiac Pacemakers, Inc. | Demand-based cardiac function therapy |
| US7572226B2 (en) | 2003-10-28 | 2009-08-11 | Cardiac Pacemakers, Inc. | System and method for monitoring autonomic balance and physical activity |
| US7657312B2 (en) | 2003-11-03 | 2010-02-02 | Cardiac Pacemakers, Inc. | Multi-site ventricular pacing therapy with parasympathetic stimulation |
| ATE482650T1 (de) * | 2003-11-03 | 2010-10-15 | Microchips Inc | Medizinprodukt zum messen von glucose |
| US20050245972A1 (en) * | 2004-04-29 | 2005-11-03 | Medtronic, Inc. | Apparatus and methods for treating arrhythmia and lowering defibrillation threshold |
| US7260431B2 (en) * | 2004-05-20 | 2007-08-21 | Cardiac Pacemakers, Inc. | Combined remodeling control therapy and anti-remodeling therapy by implantable cardiac device |
| US20050267440A1 (en) * | 2004-06-01 | 2005-12-01 | Herman Stephen J | Devices and methods for measuring and enhancing drug or analyte transport to/from medical implant |
| WO2005118166A2 (en) | 2004-06-04 | 2005-12-15 | Teva Pharmaceutical Industries, Ltd. | Pharmaceutical composition containing irbesartan |
| US20070036835A1 (en) * | 2004-07-19 | 2007-02-15 | Microchips, Inc. | Hermetically Sealed Devices for Controlled Release or Exposure of Reservoir Contents |
| JP2008508024A (ja) * | 2004-07-28 | 2008-03-21 | アーディアン インコーポレイテッド | 腎神経ブロッキング方法及び装置 |
| WO2006015299A2 (en) * | 2004-07-30 | 2006-02-09 | Microchips, Inc. | Multi-reservoir device for transdermal drug delivery and sensing |
| ATE424928T1 (de) | 2004-09-01 | 2009-03-15 | Microchips Inc | Behältervorrichtungen mit mehreren verschlüssen zur gesteuerten abgabe oder exponierung des behälterinhalts |
| WO2006050106A1 (en) * | 2004-10-28 | 2006-05-11 | Microchips, Inc. | Orthopedic and dental implant devices providing controlled drug delivery |
| US7937143B2 (en) | 2004-11-02 | 2011-05-03 | Ardian, Inc. | Methods and apparatus for inducing controlled renal neuromodulation |
| SG191562A1 (en) | 2004-11-04 | 2013-07-31 | Microchips Inc | Compression cold welding process for forming vias |
| US7413846B2 (en) * | 2004-11-15 | 2008-08-19 | Microchips, Inc. | Fabrication methods and structures for micro-reservoir devices |
| US7803168B2 (en) | 2004-12-09 | 2010-09-28 | The Foundry, Llc | Aortic valve repair |
| AU2006208131A1 (en) * | 2005-01-25 | 2006-08-03 | Microchips, Inc. | Control of drug release by transient modification of local microenvironments |
| US7587238B2 (en) | 2005-03-11 | 2009-09-08 | Cardiac Pacemakers, Inc. | Combined neural stimulation and cardiac resynchronization therapy |
| US8067026B2 (en) * | 2005-03-14 | 2011-11-29 | Boston Scientific Scimed, Inc. | Drug release regions for medical devices, which include polycyclic-structure-containing polymers |
| US7493161B2 (en) | 2005-05-10 | 2009-02-17 | Cardiac Pacemakers, Inc. | System and method to deliver therapy in presence of another therapy |
| US20070016163A1 (en) * | 2005-06-28 | 2007-01-18 | Microchips, Inc. | Medical and dental implant devices for controlled drug delivery |
| US8892197B2 (en) * | 2005-07-29 | 2014-11-18 | Medtronic, Inc. | Method and apparatus to control conduction through the heart to treat cardiac conditions |
| IL185609A0 (en) * | 2007-08-30 | 2008-01-06 | Dan Furman | Multi function senssor |
| US20090221882A1 (en) * | 2005-12-08 | 2009-09-03 | Dan Gur Furman | Implantable Biosensor Assembly and Health Monitoring system and Method including same |
| US7751883B2 (en) * | 2006-04-25 | 2010-07-06 | Eugenio Picano | System and method for promoting coronary angiogenesis |
| US9026205B2 (en) * | 2006-05-25 | 2015-05-05 | Cochlear Limited | Stimulating device |
| US8126538B2 (en) * | 2006-06-06 | 2012-02-28 | Cardiac Pacemakers, Inc. | Method and apparatus for introducing endolymphatic instrumentation |
| US7894906B2 (en) * | 2006-06-06 | 2011-02-22 | Cardiac Pacemakers, Inc. | Amelioration of chronic pain by endolymphatic stimulation |
| US7526337B2 (en) * | 2006-06-06 | 2009-04-28 | Cardiac Pacemakers, Inc. | Method and device for lymphatic system monitoring |
| US7734341B2 (en) * | 2006-06-06 | 2010-06-08 | Cardiac Pacemakers, Inc. | Method and apparatus for gastrointestinal stimulation via the lymphatic system |
| US20070282376A1 (en) | 2006-06-06 | 2007-12-06 | Shuros Allan C | Method and apparatus for neural stimulation via the lymphatic system |
| US8401654B1 (en) * | 2006-06-30 | 2013-03-19 | Boston Scientific Neuromodulation Corporation | Methods and systems for treating one or more effects of deafferentation |
| US20080015494A1 (en) * | 2006-07-11 | 2008-01-17 | Microchips, Inc. | Multi-reservoir pump device for dialysis, biosensing, or delivery of substances |
| WO2008017042A1 (en) * | 2006-08-03 | 2008-02-07 | Microchips, Inc. | Cardiac biosensor devices and methods |
| US8905999B2 (en) * | 2006-09-01 | 2014-12-09 | Cardiac Pacemakers, Inc. | Method and apparatus for endolymphatic drug delivery |
| US20090048518A1 (en) * | 2006-12-10 | 2009-02-19 | Cardio Art Technologies Ltd. | Doppler motion sensor apparatus and method of using same |
| WO2008100974A2 (en) | 2007-02-13 | 2008-08-21 | Sharma Virender K | Method and apparatus for electrical stimulation of the pancreatico-biliary system |
| DE102007010326A1 (de) * | 2007-03-02 | 2008-09-04 | Up Management Gmbh & Co Med-Systems Kg | Vorrichtung zur Infusion von mindestens einem Medikament |
| US20080294228A1 (en) * | 2007-05-23 | 2008-11-27 | Cardiac Pacemakers | Method and device for controlled stimulation of lymphatic flow |
| WO2009054758A1 (en) * | 2007-10-26 | 2009-04-30 | St. Jude Medical Ab | Methods and systems for drug titration |
| US20090137890A1 (en) * | 2007-11-27 | 2009-05-28 | Burnes John E | Devices to monitor glucose levels and ischemia |
| US20090156921A1 (en) * | 2007-12-18 | 2009-06-18 | Huisun Wang | Cardiac ablation catheter with oxygen saturation sensor |
| US8526641B2 (en) * | 2008-03-31 | 2013-09-03 | Cochlear Limited | Customizable mass arrangements for bone conduction devices |
| CA2722662A1 (en) * | 2008-05-12 | 2009-11-19 | Cardio Art Technologies, Ltd. | Integrated heart monitoring device and method of using same |
| DE102008024447A1 (de) | 2008-05-20 | 2009-11-26 | Biotronik Crm Patent Ag | Implantierbare Schockelektrodenleitung und implantierbare Defibrillationsanordnung |
| US8834446B2 (en) | 2008-06-12 | 2014-09-16 | DePuy Synthes Products, LLC | Pulsatile flux drug delivery |
| US8886306B2 (en) * | 2008-08-20 | 2014-11-11 | Cardiac Pacemakers, Inc. | Triggered high-output pacing therapy |
| US10603489B2 (en) | 2008-10-09 | 2020-03-31 | Virender K. Sharma | Methods and apparatuses for stimulating blood vessels in order to control, treat, and/or prevent a hemorrhage |
| US9079028B2 (en) | 2008-10-09 | 2015-07-14 | Virender K. Sharma | Method and apparatus for stimulating the vascular system |
| US8652129B2 (en) | 2008-12-31 | 2014-02-18 | Medtronic Ardian Luxembourg S.A.R.L. | Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation |
| WO2010111617A2 (en) | 2009-03-27 | 2010-09-30 | Van Andel Research Institute | Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use |
| WO2011032099A1 (en) | 2009-09-11 | 2011-03-17 | The Board Of Trustees Of The University Of Illinois | Methods of treating diastolic dysfunction and related conditions |
| WO2011056572A1 (en) | 2009-10-27 | 2011-05-12 | The Board Of Trustees Of The University Of Illinois | Methods of diagnosing diastolic dysfunction |
| EP2506921A4 (de) * | 2009-11-30 | 2013-10-30 | Univ South Florida | Implantierbare würfelförmige siliciumcarbid-neuralprothese |
| WO2011075393A2 (en) | 2009-12-18 | 2011-06-23 | Indiana University Research And Technology Corporation | Glucagon/glp-1 receptor co-agonists |
| US8696740B2 (en) | 2010-01-05 | 2014-04-15 | The Johns Hopkins University | Implantable pressure-actuated drug delivery systems and methods of manufacture and use |
| KR20120123443A (ko) | 2010-01-27 | 2012-11-08 | 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 | 대사 장애 및 비만 치료용 글루카곤 길항제-gip 항진제 콘쥬게이트 |
| EP2547359B1 (de) | 2010-03-15 | 2016-03-09 | The Board of Trustees of the University of Illionis | Hemmer von interaktionen, die beta-integrin-g protein-alpha-untereinheit binden |
| JP5969469B2 (ja) | 2010-06-16 | 2016-08-17 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | インスリン受容体に対して高い活性を示す単鎖インスリンアゴニスト |
| CN103313671B (zh) | 2010-10-25 | 2017-06-06 | 美敦力Af卢森堡有限责任公司 | 用于神经调节治疗的估算及反馈的装置、系统及方法 |
| US9029502B2 (en) | 2010-12-20 | 2015-05-12 | The Regents Of The University Of Michigan | Inhibitors of the epidermal growth factor receptor-heat shock protein 90 binding interaction |
| NZ612297A (en) | 2010-12-22 | 2015-10-30 | Univ Indiana Res & Tech Corp | Glucagon analogs exhibiting gip receptor activity |
| EP2678002A2 (de) * | 2011-02-25 | 2014-01-01 | Medtronic, Inc. | Therapie für nierenerkrankungen und/oder herzinsuffizienz |
| WO2012135224A1 (en) * | 2011-03-27 | 2012-10-04 | Medtronic Ardian Luxembourg Sarl | Systems and methods for local drug delivery to kidneys |
| US20120259269A1 (en) | 2011-04-08 | 2012-10-11 | Tyco Healthcare Group Lp | Iontophoresis drug delivery system and method for denervation of the renal sympathetic nerve and iontophoretic drug delivery |
| US8663202B2 (en) * | 2011-05-20 | 2014-03-04 | Advastim, Inc. | Wireless remote neurostimulator |
| CN103857408B (zh) | 2011-06-22 | 2017-04-12 | 印第安那大学科技研究公司 | 胰高血糖素/glp‑1受体协同激动剂 |
| MY169202A (en) | 2011-08-25 | 2019-02-27 | Microchips Biotech Inc | Space-efficient containment devices and method of making same |
| US10427153B2 (en) | 2011-08-25 | 2019-10-01 | Microchips Biotech, Inc. | Systems and methods for sealing a plurality of reservoirs of a microchip element with a sealing grid |
| EP2750697A4 (de) | 2011-09-02 | 2015-03-25 | Medtronic Inc | Chimäre natriuretische peptidzusammensetzungen und verfahren zu ihrer herstellung |
| US9415123B2 (en) | 2011-10-10 | 2016-08-16 | The Regents Of The University Of Michigan | Polymeric nanoparticles for ultrasound imaging and therapy |
| BR112014007124A2 (pt) | 2011-11-17 | 2017-06-13 | Univ Indiana Res & Tech Corp | superfamília de peptídeos gluxagon que exibem atividade no receptor glicocorticóide |
| CN104114183A (zh) | 2011-12-20 | 2014-10-22 | 印第安纳大学研究及科技有限公司 | 用于治疗糖尿病的基于ctp的胰岛素类似物 |
| AU2012362318B2 (en) * | 2011-12-30 | 2015-09-17 | Kibur Medical, Inc. | Implantable devices and methods for the evaluation of active agent |
| US9750568B2 (en) | 2012-03-08 | 2017-09-05 | Medtronic Ardian Luxembourg S.A.R.L. | Ovarian neuromodulation and associated systems and methods |
| EP3348220B1 (de) | 2012-03-08 | 2024-10-23 | Medtronic Ardian Luxembourg S.à.r.l. | Biomarkerprobenahme in zusammenhang mit neuromodulationsvorrichtungen sowie entsprechende systeme |
| MX2014015205A (es) | 2012-06-14 | 2015-08-14 | Ambrx Inc | Anticuerpos anti-psma conjugados a polipeptidos de ligando de receptor nuclear. |
| ES2602486T3 (es) | 2012-06-21 | 2017-02-21 | Indiana University Research And Technology Corporation | Análogos de glucagón que muestran actividad de receptor de GIP |
| SI2864350T1 (en) | 2012-06-21 | 2018-08-31 | Indiana University Research And Technology Corporation | GLUCAGON ANALOGUE ANALOGUE WITH ACTIVITY OF GIP RECEPTOR |
| CN108383902A (zh) | 2012-09-26 | 2018-08-10 | 印第安纳大学研究及科技有限公司 | 胰岛素类似物二聚体 |
| US20140110296A1 (en) | 2012-10-19 | 2014-04-24 | Medtronic Ardian Luxembourg S.A.R.L. | Packaging for Catheter Treatment Devices and Associated Devices, Systems, and Methods |
| US9919103B2 (en) * | 2012-12-21 | 2018-03-20 | Microchips Biotech, Inc. | Implantable medical device for minimally-invasive insertion |
| US9700668B2 (en) | 2013-02-28 | 2017-07-11 | Microchips Biotech, Inc. | Implantable medical device for minimally-invasive insertion |
| JP6538645B2 (ja) | 2013-03-14 | 2019-07-03 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | インスリン‐インクレチン複合物 |
| WO2015116658A1 (en) * | 2014-01-31 | 2015-08-06 | University Hospitals | Systems and methods for intrathecal delivery of a pharmaceutical agent |
| US10189908B2 (en) | 2014-02-05 | 2019-01-29 | The University Of Chicago | Chimeric antigen receptors recognizing cancer-specific TN glycopeptide variants |
| US10194979B1 (en) | 2014-03-28 | 2019-02-05 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for catheter-based renal neuromodulation |
| US10194980B1 (en) | 2014-03-28 | 2019-02-05 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for catheter-based renal neuromodulation |
| US9980766B1 (en) | 2014-03-28 | 2018-05-29 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and systems for renal neuromodulation |
| US9937124B2 (en) | 2014-09-11 | 2018-04-10 | International Business Machines Corporation | Microchip substance delivery devices having low-power electromechanical release mechanisms |
| CN108271356A (zh) | 2014-09-24 | 2018-07-10 | 印第安纳大学研究及科技有限公司 | 肠降血糖素-胰岛素缀合物 |
| EP3250609A4 (de) | 2015-01-26 | 2018-07-11 | The University of Chicago | Il13ra-alpha-2-bindende wirkstoffe und verwendung davon bei der krebsbehandlung |
| EP3250611B1 (de) | 2015-01-26 | 2021-04-21 | The University of Chicago | Car-t-zellen zur erkennung krebsspezifischer il 13r-alpha2 |
| US20180201937A1 (en) | 2015-08-04 | 2018-07-19 | The University Of Chicago | Inhibitors of cacna1a/alpha1a subunit internal ribosomal entry site (ires) and methods of treating spinocerebellar ataxia type 6 |
| US10881788B2 (en) * | 2015-10-30 | 2021-01-05 | International Business Machines Corporation | Delivery device including reactive material for programmable discrete delivery of a substance |
| US10620151B2 (en) | 2016-08-30 | 2020-04-14 | Analog Devices Global | Electrochemical sensor, and a method of forming an electrochemical sensor |
| US12188893B2 (en) | 2016-08-30 | 2025-01-07 | Analog Devices International Unlimited Company | Electrochemical sensor, and a method of forming an electrochemical sensor |
| US11268927B2 (en) | 2016-08-30 | 2022-03-08 | Analog Devices International Unlimited Company | Electrochemical sensor, and a method of forming an electrochemical sensor |
| US10751469B2 (en) * | 2017-04-07 | 2020-08-25 | Northwesten University | Computer controlled pediatric regional anesthesia |
| CN108968976B (zh) | 2017-05-31 | 2022-09-13 | 心脏起搏器股份公司 | 具有化学传感器的植入式医疗设备 |
| JP2020526483A (ja) | 2017-06-30 | 2020-08-31 | アムジエン・インコーポレーテツド | 心筋節活性化剤で心不全を治療する方法 |
| WO2019023093A1 (en) | 2017-07-26 | 2019-01-31 | Cardiac Pacemakers, Inc. | SYSTEMS AND METHODS FOR POSTURE DISAMBIGULATION |
| CN118126157A (zh) | 2017-08-03 | 2024-06-04 | 美国安进公司 | 白介素-21突变蛋白和治疗方法 |
| CN109381195B (zh) | 2017-08-10 | 2023-01-10 | 心脏起搏器股份公司 | 包括电解质传感器融合的系统和方法 |
| CN109419515B (zh) | 2017-08-23 | 2023-03-24 | 心脏起搏器股份公司 | 具有分级激活的可植入化学传感器 |
| US10640504B2 (en) | 2017-09-08 | 2020-05-05 | Amgen Inc. | Inhibitors of KRAS G12C and methods of using the same |
| SG11202002114RA (en) | 2017-09-18 | 2020-04-29 | Univ California | Claudin6 antibodies and methods of treating cancer |
| CN109864746B (zh) | 2017-12-01 | 2023-09-29 | 心脏起搏器股份公司 | 用于医学装置的多模式分析物传感器 |
| CN109864747B (zh) | 2017-12-05 | 2023-08-25 | 心脏起搏器股份公司 | 多模式分析物传感器光电子接口 |
| MX2020007291A (es) | 2018-01-12 | 2020-09-10 | Amgen Inc | Anticuerpos anti-pd-1 y metodos de tratamiento. |
| US11116561B2 (en) | 2018-01-24 | 2021-09-14 | Medtronic Ardian Luxembourg S.A.R.L. | Devices, agents, and associated methods for selective modulation of renal nerves |
| US11022579B2 (en) | 2018-02-05 | 2021-06-01 | Analog Devices International Unlimited Company | Retaining cap |
| CN108939211A (zh) * | 2018-07-31 | 2018-12-07 | 佛山市苔藓云链科技有限公司 | 一种输液监控系统 |
| US20200085776A1 (en) | 2018-09-10 | 2020-03-19 | Cardax, Inc. | Methods of Reducing C-Reactive Protein and/or Treating Cardiovascular Disease |
| US10926024B2 (en) | 2018-10-04 | 2021-02-23 | Corvictus Llc | Emergency medical intervention device |
| WO2020191344A1 (en) | 2019-03-20 | 2020-09-24 | The Regents Of The University Of California | Claudin-6 bispecific antibodies |
| DK3941946T3 (da) | 2019-03-20 | 2025-03-24 | Univ California | Claudin-6-antistoffer og lægemiddelkonjugater |
| EP3952841A1 (de) | 2019-04-09 | 2022-02-16 | The Board Of Trustees Of The University Of Illinois | Wirkstoffabsorbierte, hochporöse aktivkohle zur verbesserten wirkstoffabgabe |
| US20230190725A1 (en) | 2019-04-29 | 2023-06-22 | The Board Of Trustees Of The University Of Illinois | Mek inhibitors for corneal scarring and neovascularization |
| AU2020266083A1 (en) | 2019-04-30 | 2021-09-23 | Instituto de Medicina Molecular João Lobo Antunes | Rank pathway inhibitors in combination with CDK inhibitors |
| MX2021015937A (es) | 2019-06-24 | 2022-02-03 | Amgen Inc | Inhibicion de sirp-gamma para el tratamiento del cancer. |
| EP4021454A1 (de) | 2019-08-30 | 2022-07-06 | Research Institute at Nationwide Children's Hospital | Kupfer-atsm zur behandlung von mit mitochondrialer dysfunktion assoziierten neurodegenerativen störungen |
| CN114615903A (zh) * | 2019-10-29 | 2022-06-10 | 日本烟草国际股份有限公司 | 气溶胶产生吸用装置和方法 |
| TW202216778A (zh) | 2020-07-15 | 2022-05-01 | 美商安進公司 | Tigit及cd112r阻斷 |
| WO2022093786A1 (en) | 2020-10-29 | 2022-05-05 | Cardiac Pacemakers, Inc. | Integrated thermo-photonic chemical sensor |
| IL302850A (en) | 2020-11-12 | 2023-07-01 | Amgen Inc | Methods of treating heart failure by administering OMECAMTIV MECARBIL |
| US20240017077A1 (en) * | 2020-12-10 | 2024-01-18 | Baropace, Inc. | Method of treating drug resistant hypertension and heart failure with preserved ejection fraction by combined drug treatment with baropacing and beta blockers |
| CA3208974A1 (en) | 2021-01-20 | 2022-07-28 | Bioentre Llc | Ctla4-binding proteins and methods of treating cancer |
| EP4392130A1 (de) * | 2021-08-25 | 2024-07-03 | BaroPace, Inc. | Systeme und verfahren zur herzstimulation mit betablockern |
| WO2023137161A1 (en) | 2022-01-14 | 2023-07-20 | Amgen Inc. | Triple blockade of tigit, cd112r, and pd-l1 |
| WO2024019938A1 (en) | 2022-07-18 | 2024-01-25 | Medphlow, Llc | Integrated cartridge assembly for administration of drugs |
| US11986474B1 (en) | 2023-06-27 | 2024-05-21 | Cytokinetics, Incorporated | Methods for treating heart failure by administering cardiac sarcomere activators |
Family Cites Families (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4146029A (en) | 1974-04-23 | 1979-03-27 | Ellinwood Jr Everett H | Self-powered implanted programmable medication system and method |
| US4003379A (en) | 1974-04-23 | 1977-01-18 | Ellinwood Jr Everett H | Apparatus and method for implanted self-powered medication dispensing |
| US4146026A (en) * | 1977-03-15 | 1979-03-27 | Montalvo Victor H | Filter mask |
| US4360019A (en) | 1979-02-28 | 1982-11-23 | Andros Incorporated | Implantable infusion device |
| US4731051A (en) | 1979-04-27 | 1988-03-15 | The Johns Hopkins University | Programmable control means for providing safe and controlled medication infusion |
| US4360031A (en) | 1980-09-11 | 1982-11-23 | Medtronic, Inc. | Drug dispensing irrigatable electrode |
| GB8422876D0 (en) | 1984-09-11 | 1984-10-17 | Secr Defence | Silicon implant devices |
| US5156148A (en) * | 1987-10-06 | 1992-10-20 | Leonard Bloom | System for treating a malfunctioning heart |
| DE3735137A1 (de) | 1987-10-16 | 1989-05-03 | Siemens Ag | Anordnung zum abgeben von medikamenten bei einem implantierbaren medizinischen geraet |
| US5387419A (en) | 1988-03-31 | 1995-02-07 | The University Of Michigan | System for controlled release of antiarrhythmic agents |
| US5252294A (en) | 1988-06-01 | 1993-10-12 | Messerschmitt-Bolkow-Blohm Gmbh | Micromechanical structure |
| US5200051A (en) | 1988-11-14 | 1993-04-06 | I-Stat Corporation | Wholly microfabricated biosensors and process for the manufacture and use thereof |
| US5041107A (en) | 1989-10-06 | 1991-08-20 | Cardiac Pacemakers, Inc. | Electrically controllable, non-occluding, body implantable drug delivery system |
| US5067491A (en) | 1989-12-08 | 1991-11-26 | Becton, Dickinson And Company | Barrier coating on blood contacting devices |
| US5147297A (en) * | 1990-05-07 | 1992-09-15 | Alza Corporation | Iontophoretic delivery device |
| US5167625A (en) | 1990-10-09 | 1992-12-01 | Sarcos Group | Multiple vesicle implantable drug delivery system |
| US5524338A (en) | 1991-10-22 | 1996-06-11 | Pi Medical Corporation | Method of making implantable microelectrode |
| US5193539A (en) | 1991-12-18 | 1993-03-16 | Alfred E. Mann Foundation For Scientific Research | Implantable microstimulator |
| US5368588A (en) | 1993-02-26 | 1994-11-29 | Bettinger; David S. | Parenteral fluid medication reservoir pump |
| US5338307A (en) * | 1993-03-09 | 1994-08-16 | Ethicon, Inc. | Adaptor cap for trocar assembly |
| NZ263685A (en) * | 1993-03-15 | 1997-08-22 | Univ Michiganthe Board Of Rege | Device for controlling heart rhythm comprising eledevice for controlling heart rhythm comprising electrode assembly for attachment to the heart and a ctrode assembly for attachment to the heart and a controlled release matrix comprising an antiarrhytcontrolled release matrix comprising an antiarrhythmic agent hmic agent |
| US5366454A (en) | 1993-03-17 | 1994-11-22 | La Corporation De L'ecole Polytechnique | Implantable medication dispensing device |
| US5368704A (en) | 1993-08-06 | 1994-11-29 | Teknekron Corporation | Micro-electrochemical valves and method |
| US6129685A (en) | 1994-02-09 | 2000-10-10 | The University Of Iowa Research Foundation | Stereotactic hypothalamic obesity probe |
| US5971931A (en) | 1994-03-29 | 1999-10-26 | Raff; Gilbert Lewis | Biologic micromonitoring methods and systems |
| US5562715A (en) | 1994-12-01 | 1996-10-08 | Czura; John J. | Cardiac pulse generator |
| US5591217A (en) | 1995-01-04 | 1997-01-07 | Plexus, Inc. | Implantable stimulator with replenishable, high value capacitive power source and method therefor |
| US5556421A (en) | 1995-02-22 | 1996-09-17 | Intermedics, Inc. | Implantable medical device with enclosed physiological parameter sensors or telemetry link |
| US7611533B2 (en) | 1995-06-07 | 2009-11-03 | Cook Incorporated | Coated implantable medical device |
| US5992769A (en) | 1995-06-09 | 1999-11-30 | The Regents Of The University Of Michigan | Microchannel system for fluid delivery |
| US5713954A (en) | 1995-06-13 | 1998-02-03 | Abiomed R&D, Inc. | Extra cardiac ventricular assist device |
| US5662689A (en) | 1995-09-08 | 1997-09-02 | Medtronic, Inc. | Method and apparatus for alleviating cardioversion shock pain |
| WO1997029802A2 (en) | 1996-02-20 | 1997-08-21 | Advanced Bionics Corporation | Improved implantable microstimulator and systems employing the same |
| DE19610293C1 (de) | 1996-03-15 | 1997-07-31 | Fraunhofer Ges Forschung | Vorrichtung zur gekapselten Aufnahme eines Materials |
| US5797898A (en) | 1996-07-02 | 1998-08-25 | Massachusetts Institute Of Technology | Microchip drug delivery devices |
| DE19716683C1 (de) | 1997-04-21 | 1998-06-04 | Fraunhofer Ges Forschung | Vorrichtung zur getrennten, gekapselten Aufnahme einer Mehrzahl gleicher oder unterschiedlicher Stoffe |
| IL121286A0 (en) * | 1997-07-11 | 1998-01-04 | Pets N People Ltd | Apparatus and methods for dispensing pet care substances |
| US6001090A (en) | 1998-02-09 | 1999-12-14 | Lenhart; Douglas | Thermal pharmaceutical delivery system |
| US7208010B2 (en) | 2000-10-16 | 2007-04-24 | Conor Medsystems, Inc. | Expandable medical device for delivery of beneficial agent |
| US6757560B1 (en) | 1999-04-09 | 2004-06-29 | Novosis Pharma Ag | Transdermal delivery system (TDS) with electrode network |
| US6161047A (en) | 1998-04-30 | 2000-12-12 | Medtronic Inc. | Apparatus and method for expanding a stimulation lead body in situ |
| US6319241B1 (en) | 1998-04-30 | 2001-11-20 | Medtronic, Inc. | Techniques for positioning therapy delivery elements within a spinal cord or a brain |
| US6243608B1 (en) | 1998-06-12 | 2001-06-05 | Intermedics Inc. | Implantable device with optical telemetry |
| US6941171B2 (en) | 1998-07-06 | 2005-09-06 | Advanced Bionics Corporation | Implantable stimulator methods for treatment of incontinence and pain |
| US6908770B1 (en) | 1998-07-16 | 2005-06-21 | Board Of Regents, The University Of Texas System | Fluid based analysis of multiple analytes by a sensor array |
| EP1102560A4 (de) * | 1998-08-07 | 2003-03-12 | Infinite Biomedical Technologi | Technologie von implantierbaren vorrichtung zur detektion, anzeige und intervention bei myokardialer ischämie |
| JP2000151148A (ja) * | 1998-11-13 | 2000-05-30 | Mitsumi Electric Co Ltd | 携帯用電子機器のコード接続構造 |
| US6289237B1 (en) | 1998-12-22 | 2001-09-11 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Apparatus for energizing a remote station and related method |
| US6112116A (en) * | 1999-02-22 | 2000-08-29 | Cathco, Inc. | Implantable responsive system for sensing and treating acute myocardial infarction |
| US6178349B1 (en) | 1999-04-15 | 2001-01-23 | Medtronic, Inc. | Drug delivery neural stimulation device for treatment of cardiovascular disorders |
| US6923784B2 (en) | 1999-04-30 | 2005-08-02 | Medtronic, Inc. | Therapeutic treatment of disorders based on timing information |
| US6587719B1 (en) | 1999-07-01 | 2003-07-01 | Cyberonics, Inc. | Treatment of obesity by bilateral vagus nerve stimulation |
| US6804558B2 (en) | 1999-07-07 | 2004-10-12 | Medtronic, Inc. | System and method of communicating between an implantable medical device and a remote computer system or health care provider |
| US6334859B1 (en) | 1999-07-26 | 2002-01-01 | Zuli Holdings Ltd. | Subcutaneous apparatus and subcutaneous method for treating bodily tissues with electricity or medicaments |
| WO2001012157A1 (en) | 1999-08-18 | 2001-02-22 | Microchips, Inc. | Thermally-activated microchip chemical delivery devices |
| US6442434B1 (en) | 1999-10-19 | 2002-08-27 | Abiomed, Inc. | Methods and apparatus for providing a sufficiently stable power to a load in an energy transfer system |
| EP1229901B1 (de) | 1999-11-17 | 2009-03-18 | Boston Scientific Limited | Miniaturisierte vorrichtungen zur abgabe von molekülen in einer trägerflüssigkeit |
| EP1231981A1 (de) | 1999-11-22 | 2002-08-21 | Abiomed, Inc. | Vorrichtung zur übertragung von energie durch eine grenzschicht |
| ATE323470T1 (de) | 1999-12-10 | 2006-05-15 | Massachusetts Inst Technology | Mikrochip-arzneistoffverabreichungssysteme und herstellungsverfahren |
| US6328699B1 (en) | 2000-01-11 | 2001-12-11 | Cedars-Sinai Medical Center | Permanently implantable system and method for detecting, diagnosing and treating congestive heart failure |
| ES2420279T3 (es) | 2000-03-02 | 2013-08-23 | Microchips, Inc. | Dispositivos microfabricados y métodos para almacenamiento y exposición selectiva de productos químicos |
| WO2001091902A2 (en) | 2000-05-30 | 2001-12-06 | Massachusetts Institute Of Technology | Methods and devices for sealing microchip reservoir devices |
| US6726920B1 (en) * | 2000-09-22 | 2004-04-27 | Durect Corporation | Implantable drug delivery patch |
| EP1339312B1 (de) * | 2000-10-10 | 2006-01-04 | Microchips, Inc. | Mikrochip-reservoir-vorrichtungen mit drahtloser übertragung von energie und daten |
| AU2002224453A1 (en) | 2000-10-11 | 2002-04-22 | Microchips, Inc. | Microchip reservoir devices and facilitated corrosion of electrodes |
| CA2426937A1 (en) | 2000-10-26 | 2002-05-02 | Medtronic, Inc. | Method and apparatus to minimize the effects of a cardiac insult |
| US7218964B2 (en) | 2000-10-26 | 2007-05-15 | Medtronic, Inc. | Closed-loop neuromodulation for prevention and treatment of cardiac conditions |
| DE60140072D1 (de) | 2000-10-26 | 2009-11-12 | Meditronic Inc | Vorrichtung zur minimierung der wirkungen eines herzinsults |
| CA2426810A1 (en) | 2000-10-26 | 2002-06-13 | Medtronic, Inc. | Method and apparatus for electrically stimulating the nervous system to improve ventricular dysfunction, heart failure, and other cardiac comditions |
| DE10063612C2 (de) | 2000-12-20 | 2002-11-07 | Fraunhofer Ges Forschung | Mikrosystem zur Kontrolle der Wirkstoffabgabe aus einem Wirkstoffreservoir sowie Implantat mit Mikrosystem |
| US6666821B2 (en) | 2001-01-08 | 2003-12-23 | Medtronic, Inc. | Sensor system |
| DE60219607T2 (de) | 2001-01-09 | 2007-12-27 | Microchips, Inc., Bedford | Flexible mikrochip-vorrichtungen zur ophthalmologischen und anderen applikation |
| US6824521B2 (en) | 2001-01-22 | 2004-11-30 | Integrated Sensing Systems, Inc. | Sensing catheter system and method of fabrication |
| DE10103330B4 (de) | 2001-01-25 | 2009-04-30 | Siemens Ag | Medizinisches System zur Überwachung eines die Blutgerinnung betreffenden Messwertes eines Patienten |
| US6571125B2 (en) | 2001-02-12 | 2003-05-27 | Medtronic, Inc. | Drug delivery device |
| US7181287B2 (en) | 2001-02-13 | 2007-02-20 | Second Sight Medical Products, Inc. | Implantable drug delivery device |
| US7338522B2 (en) | 2001-02-13 | 2008-03-04 | Second Sight Medical Products, Inc. | Implantable retinal electrode array configuration for minimal retinal damage and method of reducing retinal stress |
| US6453195B1 (en) * | 2001-03-19 | 2002-09-17 | Medtronic, Inc. | Closed loop drug delivery system and remote management thereof |
| US6733485B1 (en) | 2001-05-25 | 2004-05-11 | Advanced Bionics Corporation | Microstimulator-based electrochemotherapy methods and systems |
| WO2002096389A1 (en) | 2001-05-30 | 2002-12-05 | Microchips, Inc. | Conformal coated microchip reservoir devices |
| US6875208B2 (en) | 2001-05-31 | 2005-04-05 | Massachusetts Institute Of Technology | Microchip devices with improved reservoir opening |
| WO2003032957A2 (en) | 2001-06-28 | 2003-04-24 | Microchips, Inc. | Methods for hermetically sealing microchip reservoir devices |
| US6969369B2 (en) | 2002-04-22 | 2005-11-29 | Medtronic, Inc. | Implantable drug delivery system responsive to intra-cardiac pressure |
| AU2003303288B2 (en) * | 2002-08-16 | 2006-12-07 | Microchips, Inc. | Controlled release device and method |
| WO2004022033A1 (en) * | 2002-09-04 | 2004-03-18 | Microchips, Inc. | Method and device for the controlled delivery of parathyroid hormone |
| WO2004026281A2 (en) * | 2002-09-23 | 2004-04-01 | Microchips, Inc. | Micro-reservoir osmotic release systems and microtube array device |
| EP1551499A1 (de) * | 2002-10-04 | 2005-07-13 | Microchips, Inc. | Medizinische vorrichtung zur nervenstimulation und kontrollierten verabreichung von medikamenten |
| US7632234B2 (en) | 2003-08-29 | 2009-12-15 | Medtronic, Inc. | Implantable biosensor devices for monitoring cardiac marker molecules |
| PT1662987E (pt) | 2003-09-11 | 2012-02-14 | Theranos Inc | Dispositivo médico para monitorização de analito e distribuição de droga |
| US20060041296A1 (en) | 2004-08-23 | 2006-02-23 | Medtronic, Inc. | Novel medical electrode configurations |
-
2003
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| WO2004033036A3 (en) | 2004-09-30 |
| EP1551505A2 (de) | 2005-07-13 |
| US20040106953A1 (en) | 2004-06-03 |
| US7917208B2 (en) | 2011-03-29 |
| DE60331455D1 (de) | 2010-04-08 |
| EP1551505B1 (de) | 2010-02-24 |
| AU2003279842A1 (en) | 2004-05-04 |
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