ATE458534T1 - Medizinische vorrichtung zur gesteuerten arzneimittelverabreichung sowie herzüberwachung und/oder herzstimulation - Google Patents
Medizinische vorrichtung zur gesteuerten arzneimittelverabreichung sowie herzüberwachung und/oder herzstimulationInfo
- Publication number
- ATE458534T1 ATE458534T1 AT03773170T AT03773170T ATE458534T1 AT E458534 T1 ATE458534 T1 AT E458534T1 AT 03773170 T AT03773170 T AT 03773170T AT 03773170 T AT03773170 T AT 03773170T AT E458534 T1 ATE458534 T1 AT E458534T1
- Authority
- AT
- Austria
- Prior art keywords
- medical device
- cardiac
- patient
- drug
- drug delivery
- Prior art date
Links
- 230000000747 cardiac effect Effects 0.000 title abstract 5
- 238000012544 monitoring process Methods 0.000 title abstract 3
- 239000000599 controlled substance Substances 0.000 title abstract 2
- 230000000638 stimulation Effects 0.000 title abstract 2
- 238000001647 drug administration Methods 0.000 title 1
- 238000012377 drug delivery Methods 0.000 abstract 4
- 239000003814 drug Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 3
- 108020001621 Natriuretic Peptide Proteins 0.000 abstract 2
- 102000004571 Natriuretic peptide Human genes 0.000 abstract 2
- 239000000692 natriuretic peptide Substances 0.000 abstract 2
- 206010007559 Cardiac failure congestive Diseases 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 238000013194 cardioversion Methods 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/3629—Heart stimulators in combination with non-electric therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0244—Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/35—Communication
- A61M2205/3507—Communication with implanted devices, e.g. external control
- A61M2205/3523—Communication with implanted devices, e.g. external control using telemetric means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/04—Heartbeat characteristics, e.g. ECG, blood pressure modulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16804—Flow controllers
- A61M5/16827—Flow controllers controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
- A61N1/39—Heart defibrillators
- A61N1/3956—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Electrotherapy Devices (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41600502P | 2002-10-04 | 2002-10-04 | |
| US44455403P | 2003-02-03 | 2003-02-03 | |
| US46016303P | 2003-04-03 | 2003-04-03 | |
| PCT/US2003/031596 WO2004033036A2 (en) | 2002-10-04 | 2003-10-06 | Medical device for controlled drug delivery and cardiac monitoring and/or stimulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE458534T1 true ATE458534T1 (de) | 2010-03-15 |
Family
ID=32096880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03773170T ATE458534T1 (de) | 2002-10-04 | 2003-10-06 | Medizinische vorrichtung zur gesteuerten arzneimittelverabreichung sowie herzüberwachung und/oder herzstimulation |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7917208B2 (de) |
| EP (1) | EP1551505B1 (de) |
| AT (1) | ATE458534T1 (de) |
| AU (1) | AU2003279842A1 (de) |
| DE (1) | DE60331455D1 (de) |
| WO (1) | WO2004033036A2 (de) |
Families Citing this family (169)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6302875B1 (en) | 1996-10-11 | 2001-10-16 | Transvascular, Inc. | Catheters and related devices for forming passageways between blood vessels or other anatomical structures |
| ATE290364T1 (de) * | 1999-08-18 | 2005-03-15 | Microchips Inc | Thermisch aktivierbarer microchip als abgabevorrichtung für chemikalien |
| ATE323470T1 (de) * | 1999-12-10 | 2006-05-15 | Massachusetts Inst Technology | Mikrochip-arzneistoffverabreichungssysteme und herstellungsverfahren |
| DE60144142D1 (de) | 2000-03-02 | 2011-04-14 | Microchips Inc | Mikromechanische geräte und verfahren zur speicherung und zur selektiven exposition von chemikalien |
| DE60116520T2 (de) * | 2000-10-10 | 2006-08-31 | Microchips, Inc., Bedford | Microchip-reservoir-vorrichtungen mit drahtloser übertragung von energie und daten |
| WO2002055058A2 (en) | 2001-01-09 | 2002-07-18 | Microchips, Inc. | Flexible microchip devices for ophthalmic and other applications |
| WO2002099457A1 (en) * | 2001-05-31 | 2002-12-12 | Massachusetts Inst Technology | Microchip devices with improved reservoir opening |
| US6827250B2 (en) * | 2001-06-28 | 2004-12-07 | Microchips, Inc. | Methods for hermetically sealing microchip reservoir devices |
| US7756583B2 (en) | 2002-04-08 | 2010-07-13 | Ardian, Inc. | Methods and apparatus for intravascularly-induced neuromodulation |
| US9308043B2 (en) | 2002-04-08 | 2016-04-12 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for monopolar renal neuromodulation |
| US7853333B2 (en) | 2002-04-08 | 2010-12-14 | Ardian, Inc. | Methods and apparatus for multi-vessel renal neuromodulation |
| US7162303B2 (en) | 2002-04-08 | 2007-01-09 | Ardian, Inc. | Renal nerve stimulation method and apparatus for treatment of patients |
| US20070129761A1 (en) | 2002-04-08 | 2007-06-07 | Ardian, Inc. | Methods for treating heart arrhythmia |
| US8150519B2 (en) | 2002-04-08 | 2012-04-03 | Ardian, Inc. | Methods and apparatus for bilateral renal neuromodulation |
| US7617005B2 (en) | 2002-04-08 | 2009-11-10 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
| US8131371B2 (en) | 2002-04-08 | 2012-03-06 | Ardian, Inc. | Methods and apparatus for monopolar renal neuromodulation |
| US8150520B2 (en) | 2002-04-08 | 2012-04-03 | Ardian, Inc. | Methods for catheter-based renal denervation |
| US8774913B2 (en) | 2002-04-08 | 2014-07-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for intravasculary-induced neuromodulation |
| US20080213331A1 (en) | 2002-04-08 | 2008-09-04 | Ardian, Inc. | Methods and devices for renal nerve blocking |
| US9636174B2 (en) | 2002-04-08 | 2017-05-02 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for therapeutic renal neuromodulation |
| US8347891B2 (en) | 2002-04-08 | 2013-01-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen |
| US20070135875A1 (en) | 2002-04-08 | 2007-06-14 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
| US7620451B2 (en) | 2005-12-29 | 2009-11-17 | Ardian, Inc. | Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach |
| US8145316B2 (en) | 2002-04-08 | 2012-03-27 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
| US7653438B2 (en) | 2002-04-08 | 2010-01-26 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
| US6978174B2 (en) | 2002-04-08 | 2005-12-20 | Ardian, Inc. | Methods and devices for renal nerve blocking |
| US20140018880A1 (en) | 2002-04-08 | 2014-01-16 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for monopolar renal neuromodulation |
| US9308044B2 (en) | 2002-04-08 | 2016-04-12 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for therapeutic renal neuromodulation |
| US8774922B2 (en) | 2002-04-08 | 2014-07-08 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods |
| US8145317B2 (en) | 2002-04-08 | 2012-03-27 | Ardian, Inc. | Methods for renal neuromodulation |
| DE60336727D1 (de) * | 2002-08-16 | 2011-05-26 | Microchips Inc | Vorrichtung mit kontrollierter abgabe und verfahren |
| AU2003278766A1 (en) * | 2002-09-04 | 2004-03-29 | Microchips, Inc. | Method and device for the controlled delivery of parathyroid hormone |
| US8303511B2 (en) * | 2002-09-26 | 2012-11-06 | Pacesetter, Inc. | Implantable pressure transducer system optimized for reduced thrombosis effect |
| ES2359243T3 (es) * | 2003-04-25 | 2011-05-19 | Boston Scientific Scimed, Inc. | Formulación de fármaco sólida y dispositivo para el almacenamiento y la administración controlada de la misma. |
| WO2005010240A2 (en) * | 2003-07-17 | 2005-02-03 | Microchips, Inc. | Low temperature methods for hermetically sealing reservoir devices |
| US20050055014A1 (en) * | 2003-08-04 | 2005-03-10 | Coppeta Jonathan R. | Methods for accelerated release of material from a reservoir device |
| US7392084B2 (en) | 2003-09-23 | 2008-06-24 | Cardiac Pacemakers, Inc. | Demand-based cardiac function therapy |
| US7572226B2 (en) | 2003-10-28 | 2009-08-11 | Cardiac Pacemakers, Inc. | System and method for monitoring autonomic balance and physical activity |
| US8095197B2 (en) * | 2003-11-03 | 2012-01-10 | Microchips, Inc. | Medical device for sensing glucose |
| US7657312B2 (en) | 2003-11-03 | 2010-02-02 | Cardiac Pacemakers, Inc. | Multi-site ventricular pacing therapy with parasympathetic stimulation |
| US20050245972A1 (en) * | 2004-04-29 | 2005-11-03 | Medtronic, Inc. | Apparatus and methods for treating arrhythmia and lowering defibrillation threshold |
| US7260431B2 (en) | 2004-05-20 | 2007-08-21 | Cardiac Pacemakers, Inc. | Combined remodeling control therapy and anti-remodeling therapy by implantable cardiac device |
| EP1765455A2 (de) * | 2004-06-01 | 2007-03-28 | Microchips, Inc. | Vorrichtungen und verfahren zur messung und verstärkung des wirkstoff- oder analyttransports zu/von einem medizinischen implantat |
| DE602005025755D1 (de) | 2004-06-04 | 2011-02-17 | Teva Pharma | Irbesartan enthaltende pharmazeutische zusammensetzung |
| US20070036835A1 (en) * | 2004-07-19 | 2007-02-15 | Microchips, Inc. | Hermetically Sealed Devices for Controlled Release or Exposure of Reservoir Contents |
| CN101035593B (zh) * | 2004-07-28 | 2011-05-25 | 阿迪安公司 | 肾神经阻滞的方法及装置 |
| WO2006015299A2 (en) * | 2004-07-30 | 2006-02-09 | Microchips, Inc. | Multi-reservoir device for transdermal drug delivery and sensing |
| JP5107041B2 (ja) | 2004-09-01 | 2012-12-26 | マイクロチップス・インコーポレーテッド | レザバ内容物の制御された放出または曝露のための、マルチキャップレザバデバイス |
| CA2583911A1 (en) * | 2004-10-28 | 2006-05-11 | Microchips, Inc. | Orthopedic and dental implant devices providing controlled drug delivery |
| US7937143B2 (en) | 2004-11-02 | 2011-05-03 | Ardian, Inc. | Methods and apparatus for inducing controlled renal neuromodulation |
| CN104925744A (zh) | 2004-11-04 | 2015-09-23 | 微芯片生物技术公司 | 压入式冷焊密封方法和装置 |
| US7413846B2 (en) * | 2004-11-15 | 2008-08-19 | Microchips, Inc. | Fabrication methods and structures for micro-reservoir devices |
| JP5219518B2 (ja) | 2004-12-09 | 2013-06-26 | ザ ファウンドリー, エルエルシー | 大動脈弁修復 |
| WO2006081279A2 (en) * | 2005-01-25 | 2006-08-03 | Microchips, Inc. | Control of drug release by transient modification of local microenvironments |
| US7587238B2 (en) | 2005-03-11 | 2009-09-08 | Cardiac Pacemakers, Inc. | Combined neural stimulation and cardiac resynchronization therapy |
| US8067026B2 (en) * | 2005-03-14 | 2011-11-29 | Boston Scientific Scimed, Inc. | Drug release regions for medical devices, which include polycyclic-structure-containing polymers |
| US7493161B2 (en) | 2005-05-10 | 2009-02-17 | Cardiac Pacemakers, Inc. | System and method to deliver therapy in presence of another therapy |
| WO2007001624A2 (en) * | 2005-06-28 | 2007-01-04 | Microchips, Inc. | Medical and dental implant devices for controlled drug delivery |
| US8892197B2 (en) | 2005-07-29 | 2014-11-18 | Medtronic, Inc. | Method and apparatus to control conduction through the heart to treat cardiac conditions |
| US20090221882A1 (en) * | 2005-12-08 | 2009-09-03 | Dan Gur Furman | Implantable Biosensor Assembly and Health Monitoring system and Method including same |
| IL185609A0 (en) * | 2007-08-30 | 2008-01-06 | Dan Furman | Multi function senssor |
| US7751883B2 (en) * | 2006-04-25 | 2010-07-06 | Eugenio Picano | System and method for promoting coronary angiogenesis |
| WO2007137335A1 (en) | 2006-05-25 | 2007-12-06 | Cochlear Limited | A stimulating device |
| US7526337B2 (en) * | 2006-06-06 | 2009-04-28 | Cardiac Pacemakers, Inc. | Method and device for lymphatic system monitoring |
| US7734341B2 (en) * | 2006-06-06 | 2010-06-08 | Cardiac Pacemakers, Inc. | Method and apparatus for gastrointestinal stimulation via the lymphatic system |
| US20070282376A1 (en) | 2006-06-06 | 2007-12-06 | Shuros Allan C | Method and apparatus for neural stimulation via the lymphatic system |
| US7894906B2 (en) * | 2006-06-06 | 2011-02-22 | Cardiac Pacemakers, Inc. | Amelioration of chronic pain by endolymphatic stimulation |
| US8126538B2 (en) * | 2006-06-06 | 2012-02-28 | Cardiac Pacemakers, Inc. | Method and apparatus for introducing endolymphatic instrumentation |
| US8401654B1 (en) * | 2006-06-30 | 2013-03-19 | Boston Scientific Neuromodulation Corporation | Methods and systems for treating one or more effects of deafferentation |
| US20080015494A1 (en) * | 2006-07-11 | 2008-01-17 | Microchips, Inc. | Multi-reservoir pump device for dialysis, biosensing, or delivery of substances |
| WO2008017042A1 (en) * | 2006-08-03 | 2008-02-07 | Microchips, Inc. | Cardiac biosensor devices and methods |
| US8905999B2 (en) * | 2006-09-01 | 2014-12-09 | Cardiac Pacemakers, Inc. | Method and apparatus for endolymphatic drug delivery |
| US20090048518A1 (en) * | 2006-12-10 | 2009-02-19 | Cardio Art Technologies Ltd. | Doppler motion sensor apparatus and method of using same |
| US9037244B2 (en) | 2007-02-13 | 2015-05-19 | Virender K. Sharma | Method and apparatus for electrical stimulation of the pancreatico-biliary system |
| DE102007010326A1 (de) * | 2007-03-02 | 2008-09-04 | Up Management Gmbh & Co Med-Systems Kg | Vorrichtung zur Infusion von mindestens einem Medikament |
| US20080294228A1 (en) * | 2007-05-23 | 2008-11-27 | Cardiac Pacemakers | Method and device for controlled stimulation of lymphatic flow |
| WO2009054758A1 (en) * | 2007-10-26 | 2009-04-30 | St. Jude Medical Ab | Methods and systems for drug titration |
| US20090137890A1 (en) * | 2007-11-27 | 2009-05-28 | Burnes John E | Devices to monitor glucose levels and ischemia |
| US20090156921A1 (en) * | 2007-12-18 | 2009-06-18 | Huisun Wang | Cardiac ablation catheter with oxygen saturation sensor |
| US20090248085A1 (en) * | 2008-03-31 | 2009-10-01 | Cochlear Limited | Tissue injection fixation system for a prosthetic device |
| WO2009138881A2 (en) * | 2008-05-12 | 2009-11-19 | Cardio Art Technologies, Ltd. | Method and system for monitoring a health condition |
| DE102008024447A1 (de) | 2008-05-20 | 2009-11-26 | Biotronik Crm Patent Ag | Implantierbare Schockelektrodenleitung und implantierbare Defibrillationsanordnung |
| US8834446B2 (en) | 2008-06-12 | 2014-09-16 | DePuy Synthes Products, LLC | Pulsatile flux drug delivery |
| US8886306B2 (en) * | 2008-08-20 | 2014-11-11 | Cardiac Pacemakers, Inc. | Triggered high-output pacing therapy |
| US10603489B2 (en) | 2008-10-09 | 2020-03-31 | Virender K. Sharma | Methods and apparatuses for stimulating blood vessels in order to control, treat, and/or prevent a hemorrhage |
| US9079028B2 (en) | 2008-10-09 | 2015-07-14 | Virender K. Sharma | Method and apparatus for stimulating the vascular system |
| US8652129B2 (en) | 2008-12-31 | 2014-02-18 | Medtronic Ardian Luxembourg S.A.R.L. | Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation |
| WO2010111617A2 (en) | 2009-03-27 | 2010-09-30 | Van Andel Research Institute | Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use |
| WO2011032099A1 (en) | 2009-09-11 | 2011-03-17 | The Board Of Trustees Of The University Of Illinois | Methods of treating diastolic dysfunction and related conditions |
| US20120208762A1 (en) | 2009-10-27 | 2012-08-16 | The Board Of Trustees Of The University Of Illinois | Methods of Diagnosing Diastolic Dysfunction |
| EP2506921A4 (de) * | 2009-11-30 | 2013-10-30 | Univ South Florida | Implantierbare würfelförmige siliciumcarbid-neuralprothese |
| US8703701B2 (en) | 2009-12-18 | 2014-04-22 | Indiana University Research And Technology Corporation | Glucagon/GLP-1 receptor co-agonists |
| US8696740B2 (en) | 2010-01-05 | 2014-04-15 | The Johns Hopkins University | Implantable pressure-actuated drug delivery systems and methods of manufacture and use |
| KR20120123443A (ko) | 2010-01-27 | 2012-11-08 | 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 | 대사 장애 및 비만 치료용 글루카곤 길항제-gip 항진제 콘쥬게이트 |
| ES2575160T3 (es) | 2010-03-15 | 2016-06-24 | The Board Of Trustees Of The University Of Illinois | Inhibidores de las interacciones que unen la subunidad alfa de la beta integrina-proteína G |
| JP5969469B2 (ja) | 2010-06-16 | 2016-08-17 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | インスリン受容体に対して高い活性を示す単鎖インスリンアゴニスト |
| CN103313671B (zh) | 2010-10-25 | 2017-06-06 | 美敦力Af卢森堡有限责任公司 | 用于神经调节治疗的估算及反馈的装置、系统及方法 |
| WO2012087943A2 (en) | 2010-12-20 | 2012-06-28 | The Regents Of The University Of Michigan | Inhibitors of the epidermal growth factor receptor-heat shock protein 90 binding interaction |
| US8507428B2 (en) | 2010-12-22 | 2013-08-13 | Indiana University Research And Technology Corporation | Glucagon analogs exhibiting GIP receptor activity |
| US20120277155A1 (en) * | 2011-02-25 | 2012-11-01 | Medtronic, Inc. | Therapy for kidney disease and/or heart failure |
| EP2691129A1 (de) * | 2011-03-27 | 2014-02-05 | Medtronic Ardian Luxembourg S.à.r.l. | Systeme und verfahren zur lokalen arzneimittelverabreichung an die nieren |
| JP5759615B2 (ja) | 2011-04-08 | 2015-08-05 | コヴィディエン リミテッド パートナーシップ | 腎交感神経の除神経およびイオン導入薬物送達のためのイオン導入カテーテルシステムならびに方法 |
| US8663202B2 (en) * | 2011-05-20 | 2014-03-04 | Advastim, Inc. | Wireless remote neurostimulator |
| RS56173B1 (sr) | 2011-06-22 | 2017-11-30 | Univ Indiana Res & Tech Corp | Koagonisti receptora za glukagon/glp-1 receptora |
| US10427153B2 (en) | 2011-08-25 | 2019-10-01 | Microchips Biotech, Inc. | Systems and methods for sealing a plurality of reservoirs of a microchip element with a sealing grid |
| KR102109870B1 (ko) | 2011-08-25 | 2020-05-28 | 마이크로칩스 바이오테크 인코포레이티드 | 공간 효율적 격납 장치들 및 그 제조 방법 |
| EP2750697A4 (de) | 2011-09-02 | 2015-03-25 | Medtronic Inc | Chimäre natriuretische peptidzusammensetzungen und verfahren zu ihrer herstellung |
| US9415123B2 (en) | 2011-10-10 | 2016-08-16 | The Regents Of The University Of Michigan | Polymeric nanoparticles for ultrasound imaging and therapy |
| JP6324315B2 (ja) | 2011-11-17 | 2018-05-16 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | グルココルチコイド受容体の活性を示すグルカゴンスーパーファミリーのペプチド |
| BR112014015156A2 (pt) | 2011-12-20 | 2020-10-27 | Indiana University Research And Technology Corporation | análogos de insulina à base de ctp, seus métodos de produção e uso no tratamento de hiperglicemia, bem como sequência de ácido nucleico e célula hospedeira |
| AU2012362318B2 (en) | 2011-12-30 | 2015-09-17 | Kibur Medical, Inc. | Implantable devices and methods for the evaluation of active agent |
| JP6195856B2 (ja) | 2012-03-08 | 2017-09-13 | メドトロニック アーディアン ルクセンブルク ソシエテ ア レスポンサビリテ リミテ | 神経調節装置に関するバイオマーカーのサンプリングならびに関連システムおよび方法 |
| AU2013230781B2 (en) | 2012-03-08 | 2015-12-03 | Medtronic Af Luxembourg S.A.R.L. | Ovarian neuromodulation and associated systems and methods |
| CN104619350A (zh) | 2012-06-14 | 2015-05-13 | Ambrx公司 | 结合到核受体配体多肽的抗psma抗体 |
| PE20150863A1 (es) | 2012-06-21 | 2015-06-11 | Univ Indiana Res & Tech Corp | Analogos de glucagon que exhiben actividad de receptor de gip |
| CN104583232B (zh) | 2012-06-21 | 2018-04-13 | 印第安纳大学研究及科技有限公司 | 展现gip受体活性的胰高血糖素类似物 |
| EP3395358B1 (de) | 2012-09-26 | 2019-11-06 | Indiana University Research and Technology Corporation | Insulinanalogdimere |
| US20140110296A1 (en) | 2012-10-19 | 2014-04-24 | Medtronic Ardian Luxembourg S.A.R.L. | Packaging for Catheter Treatment Devices and Associated Devices, Systems, and Methods |
| JP6435272B2 (ja) * | 2012-12-21 | 2018-12-05 | マイクロチップス バイオテック,インコーポレイテッド | 低侵襲挿入のための植え込み型医療デバイス |
| SG11201506675PA (en) | 2013-02-28 | 2015-09-29 | Microchips Biotech Inc | Implantable medical device for minimally-invasive insertion |
| JP6538645B2 (ja) | 2013-03-14 | 2019-07-03 | インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation | インスリン‐インクレチン複合物 |
| EP3102253A1 (de) * | 2014-01-31 | 2016-12-14 | University Hospitals | Systeme und verfahren zur intrathekalen verabreichung eines pharmazeutischen wirkstoffs |
| US10189908B2 (en) | 2014-02-05 | 2019-01-29 | The University Of Chicago | Chimeric antigen receptors recognizing cancer-specific TN glycopeptide variants |
| US10194980B1 (en) | 2014-03-28 | 2019-02-05 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for catheter-based renal neuromodulation |
| US10194979B1 (en) | 2014-03-28 | 2019-02-05 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for catheter-based renal neuromodulation |
| US9980766B1 (en) | 2014-03-28 | 2018-05-29 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and systems for renal neuromodulation |
| US9937124B2 (en) | 2014-09-11 | 2018-04-10 | International Business Machines Corporation | Microchip substance delivery devices having low-power electromechanical release mechanisms |
| CN108271356A (zh) | 2014-09-24 | 2018-07-10 | 印第安纳大学研究及科技有限公司 | 肠降血糖素-胰岛素缀合物 |
| WO2016123143A1 (en) | 2015-01-26 | 2016-08-04 | The University Of Chicago | CAR T-CELLS RECOGNIZING CANCER-SPECIFIC IL 13Rα2 |
| CN107683289B (zh) | 2015-01-26 | 2021-08-06 | 芝加哥大学 | IL13Rα2结合剂和其在癌症治疗中的用途 |
| WO2017024111A1 (en) | 2015-08-04 | 2017-02-09 | The University Of Chicago | Inhibitors of cacna1a/alpha1a subunit internal ribosomal entry site (ires) and methods of treating spinocerebellar ataxia type 6 |
| US10881788B2 (en) * | 2015-10-30 | 2021-01-05 | International Business Machines Corporation | Delivery device including reactive material for programmable discrete delivery of a substance |
| US10620151B2 (en) | 2016-08-30 | 2020-04-14 | Analog Devices Global | Electrochemical sensor, and a method of forming an electrochemical sensor |
| US12188893B2 (en) | 2016-08-30 | 2025-01-07 | Analog Devices International Unlimited Company | Electrochemical sensor, and a method of forming an electrochemical sensor |
| US11268927B2 (en) | 2016-08-30 | 2022-03-08 | Analog Devices International Unlimited Company | Electrochemical sensor, and a method of forming an electrochemical sensor |
| US10751469B2 (en) * | 2017-04-07 | 2020-08-25 | Northwesten University | Computer controlled pediatric regional anesthesia |
| CN108968976B (zh) | 2017-05-31 | 2022-09-13 | 心脏起搏器股份公司 | 具有化学传感器的植入式医疗设备 |
| DK3645002T3 (da) | 2017-06-30 | 2024-12-16 | Amgen Inc | Fremgangsmåder til behandling af hjertesvigt med hjerte-sarkomer-aktivatorer |
| WO2019023093A1 (en) | 2017-07-26 | 2019-01-31 | Cardiac Pacemakers, Inc. | SYSTEMS AND METHODS FOR POSTURE DISAMBIGULATION |
| EP4029877B1 (de) | 2017-08-03 | 2024-01-17 | Amgen Inc. | Interleukin-21-muteine und verfahren zur behandlung |
| CN109381195B (zh) | 2017-08-10 | 2023-01-10 | 心脏起搏器股份公司 | 包括电解质传感器融合的系统和方法 |
| CN109419515B (zh) | 2017-08-23 | 2023-03-24 | 心脏起搏器股份公司 | 具有分级激活的可植入化学传感器 |
| AU2018329920B2 (en) | 2017-09-08 | 2022-12-01 | Amgen Inc. | Inhibitors of KRAS G12C and methods of using the same |
| NO20210351A1 (en) | 2017-09-18 | 2021-03-18 | Univ California | Claudin6 antibodies and methods of treating cancer |
| CN109864746B (zh) | 2017-12-01 | 2023-09-29 | 心脏起搏器股份公司 | 用于医学装置的多模式分析物传感器 |
| CN109864747B (zh) | 2017-12-05 | 2023-08-25 | 心脏起搏器股份公司 | 多模式分析物传感器光电子接口 |
| TW201930344A (zh) | 2018-01-12 | 2019-08-01 | 美商安進公司 | 抗pd-1抗體及治療方法 |
| US11116561B2 (en) | 2018-01-24 | 2021-09-14 | Medtronic Ardian Luxembourg S.A.R.L. | Devices, agents, and associated methods for selective modulation of renal nerves |
| US11022579B2 (en) | 2018-02-05 | 2021-06-01 | Analog Devices International Unlimited Company | Retaining cap |
| CN108939211A (zh) * | 2018-07-31 | 2018-12-07 | 佛山市苔藓云链科技有限公司 | 一种输液监控系统 |
| WO2020055913A1 (en) | 2018-09-10 | 2020-03-19 | Cardax, Inc. | Methods of reducing- c-reactive protein and/or treating cardiovascular disease |
| US10926024B2 (en) | 2018-10-04 | 2021-02-23 | Corvictus Llc | Emergency medical intervention device |
| DK3941946T3 (da) | 2019-03-20 | 2025-03-24 | Univ California | Claudin-6-antistoffer og lægemiddelkonjugater |
| US20220177583A1 (en) | 2019-03-20 | 2022-06-09 | The Regents Of The University Of California | Claudin-6 bispecific antibodies |
| EP3952841A1 (de) | 2019-04-09 | 2022-02-16 | The Board Of Trustees Of The University Of Illinois | Wirkstoffabsorbierte, hochporöse aktivkohle zur verbesserten wirkstoffabgabe |
| US20230190725A1 (en) | 2019-04-29 | 2023-06-22 | The Board Of Trustees Of The University Of Illinois | Mek inhibitors for corneal scarring and neovascularization |
| JP2022530241A (ja) | 2019-04-30 | 2022-06-28 | インスチトゥート デ メディシーナ モリクラール ジョアン ロボ アントゥネス | Cdk阻害剤と組み合わせたrank経路阻害剤 |
| JP7763666B2 (ja) | 2019-06-24 | 2025-11-04 | アムジェン インコーポレイテッド | 癌治療のためのSIRPγの阻害 |
| CA3151422A1 (en) | 2019-08-30 | 2021-03-04 | Research Institute At Nationwide Children's Hospital | Copper-atsm for treating neurodegenerative disorders associated with mitochondrial dysfunction |
| EP4051035A1 (de) * | 2019-10-29 | 2022-09-07 | JT International SA | Aerosolerzeugende verdampfungsvorrichtung und verfahren |
| TW202216778A (zh) | 2020-07-15 | 2022-05-01 | 美商安進公司 | Tigit及cd112r阻斷 |
| US12551145B2 (en) | 2020-10-29 | 2026-02-17 | Cardiac Pacemakers, Inc. | Integrated thermo-photonic chemical sensor |
| DK4243825T3 (da) | 2020-11-12 | 2025-12-01 | Amgen Inc | Omecamtiv mecarbil til behandling af hjerteinsattsvigt hos udvalgte patientgrupper |
| WO2022125275A1 (en) * | 2020-12-10 | 2022-06-16 | Baropace, Inc. | Treating drug resistant hypertension and heart failure with preserved ejection fraction by combined treatment with baropacing and beta blockers |
| US20250282870A1 (en) | 2021-01-20 | 2025-09-11 | Bioentre Llc | Ctla4-binding proteins and methods of treating cancer |
| IL310772A (en) * | 2021-08-25 | 2024-04-01 | Baropace Inc | systems and treatment of the heart rhythm using beta blockers |
| WO2023137161A1 (en) | 2022-01-14 | 2023-07-20 | Amgen Inc. | Triple blockade of tigit, cd112r, and pd-l1 |
| US12121695B2 (en) | 2022-07-18 | 2024-10-22 | Medphlow, Llc | Integrated cartridge assembly for administration of drugs |
| US11986474B1 (en) | 2023-06-27 | 2024-05-21 | Cytokinetics, Incorporated | Methods for treating heart failure by administering cardiac sarcomere activators |
Family Cites Families (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4003379A (en) * | 1974-04-23 | 1977-01-18 | Ellinwood Jr Everett H | Apparatus and method for implanted self-powered medication dispensing |
| US4146029A (en) * | 1974-04-23 | 1979-03-27 | Ellinwood Jr Everett H | Self-powered implanted programmable medication system and method |
| US4146026A (en) * | 1977-03-15 | 1979-03-27 | Montalvo Victor H | Filter mask |
| US4360019A (en) * | 1979-02-28 | 1982-11-23 | Andros Incorporated | Implantable infusion device |
| US4731051A (en) * | 1979-04-27 | 1988-03-15 | The Johns Hopkins University | Programmable control means for providing safe and controlled medication infusion |
| US4360031A (en) * | 1980-09-11 | 1982-11-23 | Medtronic, Inc. | Drug dispensing irrigatable electrode |
| GB8422876D0 (en) * | 1984-09-11 | 1984-10-17 | Secr Defence | Silicon implant devices |
| US5156148A (en) * | 1987-10-06 | 1992-10-20 | Leonard Bloom | System for treating a malfunctioning heart |
| DE3735137A1 (de) * | 1987-10-16 | 1989-05-03 | Siemens Ag | Anordnung zum abgeben von medikamenten bei einem implantierbaren medizinischen geraet |
| US5387419A (en) * | 1988-03-31 | 1995-02-07 | The University Of Michigan | System for controlled release of antiarrhythmic agents |
| US5252294A (en) * | 1988-06-01 | 1993-10-12 | Messerschmitt-Bolkow-Blohm Gmbh | Micromechanical structure |
| US5200051A (en) * | 1988-11-14 | 1993-04-06 | I-Stat Corporation | Wholly microfabricated biosensors and process for the manufacture and use thereof |
| US5041107A (en) * | 1989-10-06 | 1991-08-20 | Cardiac Pacemakers, Inc. | Electrically controllable, non-occluding, body implantable drug delivery system |
| US5067491A (en) * | 1989-12-08 | 1991-11-26 | Becton, Dickinson And Company | Barrier coating on blood contacting devices |
| US5147297A (en) * | 1990-05-07 | 1992-09-15 | Alza Corporation | Iontophoretic delivery device |
| US5167625A (en) * | 1990-10-09 | 1992-12-01 | Sarcos Group | Multiple vesicle implantable drug delivery system |
| US5524338A (en) * | 1991-10-22 | 1996-06-11 | Pi Medical Corporation | Method of making implantable microelectrode |
| US5193539A (en) * | 1991-12-18 | 1993-03-16 | Alfred E. Mann Foundation For Scientific Research | Implantable microstimulator |
| US5368588A (en) * | 1993-02-26 | 1994-11-29 | Bettinger; David S. | Parenteral fluid medication reservoir pump |
| US5338307A (en) * | 1993-03-09 | 1994-08-16 | Ethicon, Inc. | Adaptor cap for trocar assembly |
| JPH07509735A (ja) | 1993-03-15 | 1995-10-26 | ザ ボード オブ リージェンツ オブ ザ ユニヴァーシティ オブ ミシガン | 抗不整脈薬の放出制御用システム |
| US5366454A (en) * | 1993-03-17 | 1994-11-22 | La Corporation De L'ecole Polytechnique | Implantable medication dispensing device |
| US5368704A (en) * | 1993-08-06 | 1994-11-29 | Teknekron Corporation | Micro-electrochemical valves and method |
| US6129685A (en) * | 1994-02-09 | 2000-10-10 | The University Of Iowa Research Foundation | Stereotactic hypothalamic obesity probe |
| US5971931A (en) * | 1994-03-29 | 1999-10-26 | Raff; Gilbert Lewis | Biologic micromonitoring methods and systems |
| US5562715A (en) * | 1994-12-01 | 1996-10-08 | Czura; John J. | Cardiac pulse generator |
| US5591217A (en) * | 1995-01-04 | 1997-01-07 | Plexus, Inc. | Implantable stimulator with replenishable, high value capacitive power source and method therefor |
| US5556421A (en) * | 1995-02-22 | 1996-09-17 | Intermedics, Inc. | Implantable medical device with enclosed physiological parameter sensors or telemetry link |
| US7611533B2 (en) | 1995-06-07 | 2009-11-03 | Cook Incorporated | Coated implantable medical device |
| US5992769A (en) * | 1995-06-09 | 1999-11-30 | The Regents Of The University Of Michigan | Microchannel system for fluid delivery |
| US5713954A (en) * | 1995-06-13 | 1998-02-03 | Abiomed R&D, Inc. | Extra cardiac ventricular assist device |
| US5662689A (en) * | 1995-09-08 | 1997-09-02 | Medtronic, Inc. | Method and apparatus for alleviating cardioversion shock pain |
| US6051017A (en) * | 1996-02-20 | 2000-04-18 | Advanced Bionics Corporation | Implantable microstimulator and systems employing the same |
| DE19610293C1 (de) * | 1996-03-15 | 1997-07-31 | Fraunhofer Ges Forschung | Vorrichtung zur gekapselten Aufnahme eines Materials |
| US5797898A (en) * | 1996-07-02 | 1998-08-25 | Massachusetts Institute Of Technology | Microchip drug delivery devices |
| DE19716683C1 (de) | 1997-04-21 | 1998-06-04 | Fraunhofer Ges Forschung | Vorrichtung zur getrennten, gekapselten Aufnahme einer Mehrzahl gleicher oder unterschiedlicher Stoffe |
| IL121286A0 (en) * | 1997-07-11 | 1998-01-04 | Pets N People Ltd | Apparatus and methods for dispensing pet care substances |
| US6001090A (en) * | 1998-02-09 | 1999-12-14 | Lenhart; Douglas | Thermal pharmaceutical delivery system |
| US7208010B2 (en) | 2000-10-16 | 2007-04-24 | Conor Medsystems, Inc. | Expandable medical device for delivery of beneficial agent |
| US6757560B1 (en) * | 1999-04-09 | 2004-06-29 | Novosis Pharma Ag | Transdermal delivery system (TDS) with electrode network |
| US6161047A (en) * | 1998-04-30 | 2000-12-12 | Medtronic Inc. | Apparatus and method for expanding a stimulation lead body in situ |
| US6319241B1 (en) * | 1998-04-30 | 2001-11-20 | Medtronic, Inc. | Techniques for positioning therapy delivery elements within a spinal cord or a brain |
| US6243608B1 (en) * | 1998-06-12 | 2001-06-05 | Intermedics Inc. | Implantable device with optical telemetry |
| US6941171B2 (en) * | 1998-07-06 | 2005-09-06 | Advanced Bionics Corporation | Implantable stimulator methods for treatment of incontinence and pain |
| US6908770B1 (en) * | 1998-07-16 | 2005-06-21 | Board Of Regents, The University Of Texas System | Fluid based analysis of multiple analytes by a sensor array |
| WO2000007497A1 (en) * | 1998-08-07 | 2000-02-17 | Infinite Biomedical Technologies, Incorporated | Implantable myocardial ischemia detection, indication and action technology |
| JP2000151148A (ja) * | 1998-11-13 | 2000-05-30 | Mitsumi Electric Co Ltd | 携帯用電子機器のコード接続構造 |
| US6289237B1 (en) * | 1998-12-22 | 2001-09-11 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Apparatus for energizing a remote station and related method |
| US6112116A (en) * | 1999-02-22 | 2000-08-29 | Cathco, Inc. | Implantable responsive system for sensing and treating acute myocardial infarction |
| US6178349B1 (en) * | 1999-04-15 | 2001-01-23 | Medtronic, Inc. | Drug delivery neural stimulation device for treatment of cardiovascular disorders |
| US6923784B2 (en) * | 1999-04-30 | 2005-08-02 | Medtronic, Inc. | Therapeutic treatment of disorders based on timing information |
| US6587719B1 (en) * | 1999-07-01 | 2003-07-01 | Cyberonics, Inc. | Treatment of obesity by bilateral vagus nerve stimulation |
| US6804558B2 (en) * | 1999-07-07 | 2004-10-12 | Medtronic, Inc. | System and method of communicating between an implantable medical device and a remote computer system or health care provider |
| US6334859B1 (en) * | 1999-07-26 | 2002-01-01 | Zuli Holdings Ltd. | Subcutaneous apparatus and subcutaneous method for treating bodily tissues with electricity or medicaments |
| ATE290364T1 (de) * | 1999-08-18 | 2005-03-15 | Microchips Inc | Thermisch aktivierbarer microchip als abgabevorrichtung für chemikalien |
| US6442434B1 (en) | 1999-10-19 | 2002-08-27 | Abiomed, Inc. | Methods and apparatus for providing a sufficiently stable power to a load in an energy transfer system |
| EP2308522A3 (de) * | 1999-11-17 | 2012-02-29 | Boston Scientific Limited | Miniaturisierte Vorrichtungen zur Abgabe von Molekülen in einer Trägerflüssigkeit |
| WO2001037926A1 (en) | 1999-11-22 | 2001-05-31 | Abiomed, Inc. | Apparatus for transferring energy across a boundary |
| ATE323470T1 (de) * | 1999-12-10 | 2006-05-15 | Massachusetts Inst Technology | Mikrochip-arzneistoffverabreichungssysteme und herstellungsverfahren |
| US6328699B1 (en) | 2000-01-11 | 2001-12-11 | Cedars-Sinai Medical Center | Permanently implantable system and method for detecting, diagnosing and treating congestive heart failure |
| DE60144142D1 (de) * | 2000-03-02 | 2011-04-14 | Microchips Inc | Mikromechanische geräte und verfahren zur speicherung und zur selektiven exposition von chemikalien |
| AU2001265128A1 (en) * | 2000-05-30 | 2001-12-11 | Massachusetts Institute Of Technology | Methods and devices for sealing microchip reservoir devices |
| US6726920B1 (en) * | 2000-09-22 | 2004-04-27 | Durect Corporation | Implantable drug delivery patch |
| DE60116520T2 (de) * | 2000-10-10 | 2006-08-31 | Microchips, Inc., Bedford | Microchip-reservoir-vorrichtungen mit drahtloser übertragung von energie und daten |
| AU2002224453A1 (en) * | 2000-10-11 | 2002-04-22 | Microchips, Inc. | Microchip reservoir devices and facilitated corrosion of electrodes |
| EP1330287B1 (de) * | 2000-10-26 | 2009-07-29 | Medtronic, Inc. | Gerät zur minimierung der wirkungen einer herzverletzung |
| CA2426810A1 (en) * | 2000-10-26 | 2002-06-13 | Medtronic, Inc. | Method and apparatus for electrically stimulating the nervous system to improve ventricular dysfunction, heart failure, and other cardiac comditions |
| CA2426944A1 (en) * | 2000-10-26 | 2002-05-02 | Medtronic, Inc. | Method and apparatus to minimize the effects of a cardiac insult |
| DE10063612C2 (de) | 2000-12-20 | 2002-11-07 | Fraunhofer Ges Forschung | Mikrosystem zur Kontrolle der Wirkstoffabgabe aus einem Wirkstoffreservoir sowie Implantat mit Mikrosystem |
| US6666821B2 (en) * | 2001-01-08 | 2003-12-23 | Medtronic, Inc. | Sensor system |
| WO2002055058A2 (en) * | 2001-01-09 | 2002-07-18 | Microchips, Inc. | Flexible microchip devices for ophthalmic and other applications |
| US6824521B2 (en) * | 2001-01-22 | 2004-11-30 | Integrated Sensing Systems, Inc. | Sensing catheter system and method of fabrication |
| DE10103330B4 (de) * | 2001-01-25 | 2009-04-30 | Siemens Ag | Medizinisches System zur Überwachung eines die Blutgerinnung betreffenden Messwertes eines Patienten |
| US6571125B2 (en) * | 2001-02-12 | 2003-05-27 | Medtronic, Inc. | Drug delivery device |
| US7338522B2 (en) | 2001-02-13 | 2008-03-04 | Second Sight Medical Products, Inc. | Implantable retinal electrode array configuration for minimal retinal damage and method of reducing retinal stress |
| US7181287B2 (en) * | 2001-02-13 | 2007-02-20 | Second Sight Medical Products, Inc. | Implantable drug delivery device |
| US6453195B1 (en) * | 2001-03-19 | 2002-09-17 | Medtronic, Inc. | Closed loop drug delivery system and remote management thereof |
| US6733485B1 (en) * | 2001-05-25 | 2004-05-11 | Advanced Bionics Corporation | Microstimulator-based electrochemotherapy methods and systems |
| JP2004533297A (ja) * | 2001-05-29 | 2004-11-04 | メドトロニック・インコーポレーテッド | 心臓病の予防及び処置のための閉ループ神経調節システム |
| US6973718B2 (en) * | 2001-05-30 | 2005-12-13 | Microchips, Inc. | Methods for conformal coating and sealing microchip reservoir devices |
| WO2002099457A1 (en) | 2001-05-31 | 2002-12-12 | Massachusetts Inst Technology | Microchip devices with improved reservoir opening |
| US6827250B2 (en) | 2001-06-28 | 2004-12-07 | Microchips, Inc. | Methods for hermetically sealing microchip reservoir devices |
| US6969369B2 (en) * | 2002-04-22 | 2005-11-29 | Medtronic, Inc. | Implantable drug delivery system responsive to intra-cardiac pressure |
| DE60336727D1 (de) * | 2002-08-16 | 2011-05-26 | Microchips Inc | Vorrichtung mit kontrollierter abgabe und verfahren |
| AU2003278766A1 (en) * | 2002-09-04 | 2004-03-29 | Microchips, Inc. | Method and device for the controlled delivery of parathyroid hormone |
| AU2003278881A1 (en) * | 2002-09-23 | 2004-04-08 | Microchips, Inc. | Micro-reservoir osmotic release systems and microtube array device |
| EP1551499A1 (de) * | 2002-10-04 | 2005-07-13 | Microchips, Inc. | Medizinische vorrichtung zur nervenstimulation und kontrollierten verabreichung von medikamenten |
| US7632234B2 (en) * | 2003-08-29 | 2009-12-15 | Medtronic, Inc. | Implantable biosensor devices for monitoring cardiac marker molecules |
| KR101556457B1 (ko) * | 2003-09-11 | 2015-10-01 | 테라노스, 인코포레이티드 | 피분석물의 모니터링 및 약물 전달을 위한 의료 기기 |
| US20060041296A1 (en) * | 2004-08-23 | 2006-02-23 | Medtronic, Inc. | Novel medical electrode configurations |
-
2003
- 2003-10-06 AU AU2003279842A patent/AU2003279842A1/en not_active Abandoned
- 2003-10-06 WO PCT/US2003/031596 patent/WO2004033036A2/en not_active Ceased
- 2003-10-06 DE DE60331455T patent/DE60331455D1/de not_active Expired - Lifetime
- 2003-10-06 AT AT03773170T patent/ATE458534T1/de not_active IP Right Cessation
- 2003-10-06 EP EP03773170A patent/EP1551505B1/de not_active Expired - Lifetime
- 2003-10-06 US US10/679,772 patent/US7917208B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7917208B2 (en) | 2011-03-29 |
| WO2004033036A2 (en) | 2004-04-22 |
| DE60331455D1 (de) | 2010-04-08 |
| EP1551505A2 (de) | 2005-07-13 |
| WO2004033036A3 (en) | 2004-09-30 |
| EP1551505B1 (de) | 2010-02-24 |
| AU2003279842A1 (en) | 2004-05-04 |
| US20040106953A1 (en) | 2004-06-03 |
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| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |