ATE459369T1 - Verfahren zur behandlung von entzündungen - Google Patents
Verfahren zur behandlung von entzündungenInfo
- Publication number
- ATE459369T1 ATE459369T1 AT06006242T AT06006242T ATE459369T1 AT E459369 T1 ATE459369 T1 AT E459369T1 AT 06006242 T AT06006242 T AT 06006242T AT 06006242 T AT06006242 T AT 06006242T AT E459369 T1 ATE459369 T1 AT E459369T1
- Authority
- AT
- Austria
- Prior art keywords
- treating inflammation
- psoriasis
- antibody
- binds
- seq
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Liquid Crystal Substances (AREA)
- Apparatuses For Bulk Treatment Of Fruits And Vegetables And Apparatuses For Preparing Feeds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47089899A | 1999-12-23 | 1999-12-23 | |
| US21334100P | 2000-06-22 | 2000-06-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE459369T1 true ATE459369T1 (de) | 2010-03-15 |
Family
ID=26907985
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06006242T ATE459369T1 (de) | 1999-12-23 | 2000-12-22 | Verfahren zur behandlung von entzündungen |
| AT00988365T ATE339450T1 (de) | 1999-12-23 | 2000-12-22 | Verfahren zur behandlung von entzündungen |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00988365T ATE339450T1 (de) | 1999-12-23 | 2000-12-22 | Verfahren zur behandlung von entzündungen |
Country Status (10)
| Country | Link |
|---|---|
| EP (6) | EP1244708B8 (de) |
| JP (3) | JP2003535037A (de) |
| AT (2) | ATE459369T1 (de) |
| AU (1) | AU2458001A (de) |
| CA (1) | CA2395406C (de) |
| DE (2) | DE60043957D1 (de) |
| DK (1) | DK1616575T3 (de) |
| ES (1) | ES2387394T3 (de) |
| PT (1) | PT1616575E (de) |
| WO (1) | WO2001046261A1 (de) |
Families Citing this family (113)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU739420B2 (en) * | 1997-11-26 | 2001-10-11 | Zymogenetics Inc. | Mammalian cytokine-like polypeptide-10 |
| US7198789B2 (en) | 1998-03-17 | 2007-04-03 | Genetics Institute, Llc | Methods and compositions for modulating interleukin-21 receptor activity |
| US6057128A (en) | 1998-03-17 | 2000-05-02 | Genetics Institute, Inc. | MU-1, member of the cytokine receptor family |
| US7189400B2 (en) | 1998-03-17 | 2007-03-13 | Genetics Institute, Llc | Methods of treatment with antagonists of MU-1 |
| US7122632B2 (en) | 1999-12-23 | 2006-10-17 | Zymogenetics, Inc. | Soluble Interleukin-20 receptor |
| US6610286B2 (en) | 1999-12-23 | 2003-08-26 | Zymogenetics, Inc. | Method for treating inflammation using soluble receptors to interleukin-20 |
| WO2001046261A1 (en) * | 1999-12-23 | 2001-06-28 | Zymogenetics, Inc. | Method for treating inflammation |
| DK1246846T3 (da) | 1999-12-23 | 2008-12-08 | Zymogenetics Inc | Oplöselig interleukin-20-receptor |
| US20030023033A1 (en) * | 2001-07-26 | 2003-01-30 | Laure Dumoutier | Novel class II cytokine receptors and uses thereof |
| EP2177616B1 (de) | 2000-08-08 | 2012-02-29 | ZymoGenetics, Inc. | Lösliche Zcyctor 11 Cytokinrezeptoren |
| WO2002022153A2 (en) * | 2000-09-15 | 2002-03-21 | Zymogenetics, Inc. | Use of a polypeptide comprising the extracellular domains of il-20rb for the treatment of inflammation |
| EP1992643A3 (de) | 2001-06-20 | 2008-12-10 | Genentech, Inc. | Zusammensetzungen und Verfahren zur Behandlung und Diagnose von Tumoren |
| US20050272120A1 (en) | 2001-06-20 | 2005-12-08 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| EP1432431B1 (de) * | 2001-10-04 | 2017-05-10 | Genetics Institute LLC | Verfahren und zusammensetzungen zur modulierung der wirkung des interleukin-21 |
| AU2002357283B2 (en) | 2001-12-17 | 2007-08-16 | Zymogenetics, Inc. | Method for treating cervical cancer |
| EP1498137A1 (de) * | 2002-04-25 | 2005-01-19 | Chugai Seiyaku Kabushiki Kaisha | Mittel zur behandlung von lungenkrebs |
| US20050276812A1 (en) | 2004-06-01 | 2005-12-15 | Genentech, Inc. | Antibody-drug conjugates and methods |
| AU2004223837C1 (en) * | 2003-03-24 | 2012-03-15 | Zymogenetics, Inc. | Anti-IL-22RA antibodies and binding partners and methods of using in inflammation |
| EP1653995A1 (de) | 2003-08-08 | 2006-05-10 | Novo Nordisk A/S | Interleukin-20 zur behandlung und diagnose von mit neovaskularization verbunden zuständen |
| CN107213469A (zh) | 2003-11-06 | 2017-09-29 | 西雅图基因公司 | 能够与配体偶联的单甲基缬氨酸化合物 |
| WO2005052000A2 (en) | 2003-11-21 | 2005-06-09 | Zymogenetics, Inc. | Anti-il-20 antibodies and binding partners and methods of using in inflammation |
| KR101270829B1 (ko) | 2004-09-23 | 2013-06-07 | 제넨테크, 인크. | 시스테인 유전자조작 항체 및 접합체 |
| US20100111856A1 (en) | 2004-09-23 | 2010-05-06 | Herman Gill | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
| BRPI0516975A (pt) | 2004-10-22 | 2008-09-30 | Zymogenetics Inc | anticorpo ou seu fragmento de ligação a antìgeno, composição farmacêutica, imunoconjugado, hibridoma, anticorpo monoclonal, e, uso de um anticorpo ou seu fragmento de ligação a antìgeno |
| MX2010013565A (es) * | 2008-06-30 | 2011-01-14 | Novo Nordisk As | Anticuerpos de interleucina-20 anti-humanos. |
| CA2739794A1 (en) * | 2008-10-07 | 2010-04-15 | National Cheng Kung University | Use of il-20 antagonists for treating rheumatoid arthritis and osteoporosis |
| US8454956B2 (en) | 2009-08-31 | 2013-06-04 | National Cheng Kung University | Methods for treating rheumatoid arthritis and osteoporosis with anti-IL-20 antibodies |
| CA2809819A1 (en) | 2009-09-09 | 2011-03-17 | Centrose, Llc | Extracellular targeted drug conjugates |
| JP2013514795A (ja) | 2009-12-22 | 2013-05-02 | ノバルティス アーゲー | 治療における使用のための四価cd47抗体定常領域融合タンパク質 |
| WO2011130598A1 (en) | 2010-04-15 | 2011-10-20 | Spirogen Limited | Pyrrolobenzodiazepines and conjugates thereof |
| MX336540B (es) | 2010-06-08 | 2016-01-22 | Genentech Inc | Conjugados y anticuerpos manipulados geneticamente con cisteina. |
| ES2544608T3 (es) | 2010-11-17 | 2015-09-02 | Genentech, Inc. | Conjugados de anticuerpo y de alaninil-maitansinol |
| MX2013013054A (es) | 2011-05-12 | 2014-02-20 | Genentech Inc | Metodo de monitoreo de lc-ms/ms de reaccion multiple para detectar anticuerpos terapeuticos en muestras de animales utilizando peptidos de firma de estructura. |
| US20140193408A1 (en) | 2011-06-16 | 2014-07-10 | Novartis Ag | Soluble proteins for use as therapeutics |
| UY34347A (es) | 2011-09-26 | 2013-04-30 | Novartis Ag | Proteínas de función dual para tratar trastornos metabólicos |
| UY34346A (es) | 2011-09-26 | 2013-04-30 | Novartis Ag | Proteínas de fusión para tratar trastornos metabólicos |
| WO2013055987A1 (en) | 2011-10-14 | 2013-04-18 | Spirogen Sàrl | Pyrrolobenzodiazepines and conjugates thereof |
| EP2812445A2 (de) | 2012-02-10 | 2014-12-17 | Novo Nordisk A/S | Verfahren im zusammenhang mit der behandlung von entzündungserkrankungen und -störungen |
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| US9221904B2 (en) | 2012-07-19 | 2015-12-29 | National Cheng Kung University | Treatment of osteoarthritis using IL-20 antagonists |
| US8603470B1 (en) | 2012-08-07 | 2013-12-10 | National Cheng Kung University | Use of IL-20 antagonists for treating liver diseases |
| US8852588B2 (en) | 2012-08-07 | 2014-10-07 | National Cheng Kung University | Treating allergic airway disorders using anti-IL-20 receptor antibodies |
| KR101645905B1 (ko) | 2012-10-12 | 2016-08-04 | 스피로즌 살 | 피롤로벤조디아제핀 및 그의 컨주게이트 |
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| ES2680153T3 (es) | 2012-10-12 | 2018-09-04 | Adc Therapeutics Sa | Conjugados de anticuerpos anti-PSMA-pirrolobenzodiazepinas |
| PL2906251T3 (pl) | 2012-10-12 | 2018-02-28 | Adc Therapeutics Sa | Koniugaty pirolobenzodiazepina-przeciwciało anty-CD22 |
| MX364328B (es) | 2012-10-12 | 2019-04-23 | Medimmune Ltd | Conjugados del anticuerpo pirrolobenzodiazepina. |
| HRP20181646T2 (hr) | 2012-10-12 | 2019-08-09 | Adc Therapeutics Sa | Konjugati pirolobenzodiazepin - anti-psma protutijela |
| WO2014057117A1 (en) | 2012-10-12 | 2014-04-17 | Adc Therapeutics Sàrl | Pyrrolobenzodiazepine-antibody conjugates |
| CN105246894A (zh) | 2012-12-21 | 2016-01-13 | 斯皮罗根有限公司 | 用于治疗增殖性和自身免疫疾病的非对称吡咯并苯并二氮杂卓二聚物 |
| AU2013366493B2 (en) | 2012-12-21 | 2017-08-24 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
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| US5567584A (en) | 1988-01-22 | 1996-10-22 | Zymogenetics, Inc. | Methods of using biologically active dimerized polypeptide fusions to detect PDGF |
| PT873405E (pt) | 1996-01-11 | 2005-01-31 | Immunex Corp | Elementos de sequencia que aumentam a expressao (ease) para sistemas de expressao eucarioticos |
| US5945511A (en) | 1997-02-20 | 1999-08-31 | Zymogenetics, Inc. | Class II cytokine receptor |
| US6486301B1 (en) * | 1997-07-16 | 2002-11-26 | Human Genome Sciences, Inc. | Interleukin-20 |
| WO1999003982A1 (en) * | 1997-07-16 | 1999-01-28 | Human Genome Sciences, Inc. | Interleukin-20 |
| AU739420B2 (en) * | 1997-11-26 | 2001-10-11 | Zymogenetics Inc. | Mammalian cytokine-like polypeptide-10 |
| EP1062332A2 (de) | 1998-03-09 | 2000-12-27 | Schering Corporation | Menschliche rezeptorproteine; und verwandte reagenzien und verfahren |
| AU4411699A (en) * | 1998-06-05 | 1999-12-20 | Human Genome Sciences, Inc. | Interferon receptor hkaef92 |
| EP1141008A1 (de) * | 1998-12-31 | 2001-10-10 | Millennium Pharmaceuticals, Inc. | Cytokinin klasse ii rezeptor-ähnliche proteine und für diese kodierende nukleinsäuren |
| DK1246846T3 (da) * | 1999-12-23 | 2008-12-08 | Zymogenetics Inc | Oplöselig interleukin-20-receptor |
| WO2001046261A1 (en) * | 1999-12-23 | 2001-06-28 | Zymogenetics, Inc. | Method for treating inflammation |
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2000
- 2000-12-22 WO PCT/US2000/035305 patent/WO2001046261A1/en not_active Ceased
- 2000-12-22 AT AT06006242T patent/ATE459369T1/de not_active IP Right Cessation
- 2000-12-22 CA CA2395406A patent/CA2395406C/en not_active Expired - Fee Related
- 2000-12-22 AU AU24580/01A patent/AU2458001A/en not_active Abandoned
- 2000-12-22 EP EP00988365A patent/EP1244708B8/de not_active Expired - Lifetime
- 2000-12-22 PT PT05020542T patent/PT1616575E/pt unknown
- 2000-12-22 DK DK05020542.6T patent/DK1616575T3/da active
- 2000-12-22 AT AT00988365T patent/ATE339450T1/de active
- 2000-12-22 ES ES05020542T patent/ES2387394T3/es not_active Expired - Lifetime
- 2000-12-22 EP EP06006242A patent/EP1743648B1/de not_active Expired - Lifetime
- 2000-12-22 EP EP10166530A patent/EP2248828A1/de not_active Withdrawn
- 2000-12-22 EP EP10180117A patent/EP2295078A3/de not_active Withdrawn
- 2000-12-22 DE DE60043957T patent/DE60043957D1/de not_active Expired - Lifetime
- 2000-12-22 DE DE60030769T patent/DE60030769T2/de not_active Expired - Lifetime
- 2000-12-22 EP EP05020542A patent/EP1616575B1/de not_active Expired - Lifetime
- 2000-12-22 JP JP2001547170A patent/JP2003535037A/ja not_active Withdrawn
- 2000-12-22 EP EP10180136A patent/EP2295079A3/de not_active Withdrawn
-
2011
- 2011-06-16 JP JP2011133929A patent/JP2012025737A/ja active Pending
- 2011-09-27 JP JP2011210306A patent/JP2012025766A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1743648B1 (de) | 2010-03-03 |
| EP1244708B8 (de) | 2007-03-07 |
| DE60030769D1 (de) | 2006-10-26 |
| ES2387394T3 (es) | 2012-09-21 |
| PT1616575E (pt) | 2012-08-07 |
| JP2003535037A (ja) | 2003-11-25 |
| EP1743648A1 (de) | 2007-01-17 |
| CA2395406C (en) | 2013-07-16 |
| DE60030769T2 (de) | 2007-10-25 |
| EP2295079A2 (de) | 2011-03-16 |
| JP2012025737A (ja) | 2012-02-09 |
| DK1616575T3 (da) | 2012-09-10 |
| CA2395406A1 (en) | 2001-06-28 |
| JP2012025766A (ja) | 2012-02-09 |
| EP1616575A1 (de) | 2006-01-18 |
| WO2001046261A1 (en) | 2001-06-28 |
| AU2458001A (en) | 2001-07-03 |
| EP1244708A1 (de) | 2002-10-02 |
| EP2295078A2 (de) | 2011-03-16 |
| EP2295078A3 (de) | 2011-03-23 |
| EP2248828A1 (de) | 2010-11-10 |
| EP1616575B1 (de) | 2012-06-06 |
| EP2295079A3 (de) | 2011-03-23 |
| EP1244708B1 (de) | 2006-09-13 |
| ATE339450T1 (de) | 2006-10-15 |
| DE60043957D1 (de) | 2010-04-15 |
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