ATE459976T1 - Faims apparatur und verfahren unter verwendung eines trägergases von gemischter zusammensetzung - Google Patents

Faims apparatur und verfahren unter verwendung eines trägergases von gemischter zusammensetzung

Info

Publication number
ATE459976T1
ATE459976T1 AT01914868T AT01914868T ATE459976T1 AT E459976 T1 ATE459976 T1 AT E459976T1 AT 01914868 T AT01914868 T AT 01914868T AT 01914868 T AT01914868 T AT 01914868T AT E459976 T1 ATE459976 T1 AT E459976T1
Authority
AT
Austria
Prior art keywords
carrier gas
mixed composition
ions
faims apparatus
ion
Prior art date
Application number
AT01914868T
Other languages
English (en)
Inventor
Roger Guevremont
Randy Purves
David Barnett
Original Assignee
Ca Nat Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ca Nat Research Council filed Critical Ca Nat Research Council
Application granted granted Critical
Publication of ATE459976T1 publication Critical patent/ATE459976T1/de

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Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/624—Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Electrochemistry (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT01914868T 2000-03-14 2001-03-14 Faims apparatur und verfahren unter verwendung eines trägergases von gemischter zusammensetzung ATE459976T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18908500P 2000-03-14 2000-03-14
PCT/CA2001/000310 WO2001069646A2 (en) 2000-03-14 2001-03-14 Faims apparatus and method using carrier gas of mixed composition

Publications (1)

Publication Number Publication Date
ATE459976T1 true ATE459976T1 (de) 2010-03-15

Family

ID=22695859

Family Applications (2)

Application Number Title Priority Date Filing Date
AT01913444T ATE308115T1 (de) 2000-03-14 2001-03-14 Faims apparatur und verfahren mit lasergestützter ionisationsquelle
AT01914868T ATE459976T1 (de) 2000-03-14 2001-03-14 Faims apparatur und verfahren unter verwendung eines trägergases von gemischter zusammensetzung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT01913444T ATE308115T1 (de) 2000-03-14 2001-03-14 Faims apparatur und verfahren mit lasergestützter ionisationsquelle

Country Status (8)

Country Link
US (6) US6703609B2 (de)
EP (4) EP1266394B1 (de)
JP (1) JP4783533B2 (de)
AT (2) ATE308115T1 (de)
AU (10) AU3907301A (de)
CA (6) CA2402812C (de)
DE (2) DE60114394T2 (de)
WO (6) WO2001069647A2 (de)

Families Citing this family (148)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6690004B2 (en) * 1999-07-21 2004-02-10 The Charles Stark Draper Laboratory, Inc. Method and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry
US6806463B2 (en) 1999-07-21 2004-10-19 The Charles Stark Draper Laboratory, Inc. Micromachined field asymmetric ion mobility filter and detection system
US6815669B1 (en) 1999-07-21 2004-11-09 The Charles Stark Draper Laboratory, Inc. Longitudinal field driven ion mobility filter and detection system
US7148477B2 (en) * 1999-07-21 2006-12-12 Sionex Corporation System for trajectory-based ion species identification
US6815668B2 (en) 1999-07-21 2004-11-09 The Charles Stark Draper Laboratory, Inc. Method and apparatus for chromatography-high field asymmetric waveform ion mobility spectrometry
US7005632B2 (en) 2002-04-12 2006-02-28 Sionex Corporation Method and apparatus for control of mobility-based ion species identification
US7098449B1 (en) 1999-07-21 2006-08-29 The Charles Stark Draper Laboratory, Inc. Spectrometer chip assembly
US7129482B2 (en) * 1999-07-21 2006-10-31 Sionex Corporation Explosives detection using differential ion mobility spectrometry
US7399958B2 (en) * 1999-07-21 2008-07-15 Sionex Corporation Method and apparatus for enhanced ion mobility based sample analysis using various analyzer configurations
US7157700B2 (en) * 2001-06-30 2007-01-02 Sionex Corporation System for collection of data and identification of unknown ion species in an electric field
US7057168B2 (en) 1999-07-21 2006-06-06 Sionex Corporation Systems for differential ion mobility analysis
AU3907301A (en) * 2000-03-14 2001-09-24 Ca Nat Research Council Faims apparatus and method with laser-based ionization source
AU2001239076A1 (en) * 2000-03-14 2001-09-24 National Research Council Canada Tandem high field asymmetric waveform ion mobility spectrometry (faims)/ion mobility spectrometry
CA2402793C (en) * 2000-03-14 2009-06-16 National Research Council Of Canada Improved parallel plate geometry faims apparatus and method
AU2001275364A1 (en) * 2000-06-09 2001-12-24 University Of Delaware System and method for chemical analysis using laser ablation
WO2002083276A1 (en) * 2001-04-17 2002-10-24 The Charles Stark Draper Laboratory, Inc. Methods and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry
US7586088B2 (en) 2001-06-21 2009-09-08 Micromass Uk Limited Mass spectrometer and method of mass spectrometry
US7119328B2 (en) 2001-06-30 2006-10-10 Sionex Corporation System for DMS peak resolution
WO2003005016A1 (en) * 2001-06-30 2003-01-16 Sionex Corporation System for collection of data and identification of unknown ion species in an electric field
US7274015B2 (en) 2001-08-08 2007-09-25 Sionex Corporation Capacitive discharge plasma ion source
US7091481B2 (en) * 2001-08-08 2006-08-15 Sionex Corporation Method and apparatus for plasma generation
US6727496B2 (en) * 2001-08-14 2004-04-27 Sionex Corporation Pancake spectrometer
JP2005509888A (ja) * 2001-11-16 2005-04-14 ウオーターズ・インベストメンツ・リミテツド Ｍａｌｄｉターゲット上への濃縮、脱塩および被着の並列処理
US7223967B2 (en) * 2002-02-08 2007-05-29 Thermo Finnigan Llc Side-to-side FAIMS apparatus having an analyzer region with non-uniform spacing and method therefore
US6787765B2 (en) * 2002-02-08 2004-09-07 Ionalytics Corporation FAIMS with non-destructive detection of selectively transmitted ions
US7034286B2 (en) 2002-02-08 2006-04-25 Ionalytics Corporation FAIMS apparatus having plural ion inlets and method therefore
US6987262B2 (en) * 2002-02-08 2006-01-17 Ionalytics Corporation FAIMS apparatus and method for detecting trace amounts of a vapour in a carrier gas
US7026612B2 (en) * 2002-02-08 2006-04-11 Ionalytics Corporation FAIMS apparatus and method using carrier gases that contain a trace amount of a dopant species
US7005633B2 (en) * 2002-02-08 2006-02-28 Ionalytics Corporation Method and apparatus for desolvating ions for introduction into a FAIMS analyzer region
US7122794B1 (en) 2002-02-21 2006-10-17 Sionex Corporation Systems and methods for ion mobility control
FI118277B (fi) 2002-03-25 2007-09-14 Environics Oy Kennorakenne, laite ja menetelmä
US6906319B2 (en) 2002-05-17 2005-06-14 Micromass Uk Limited Mass spectrometer
DE10236344B4 (de) * 2002-08-08 2007-03-29 Bruker Daltonik Gmbh Ionisieren an Atmosphärendruck für massenspektrometrische Analysen
CA2502445C (en) * 2002-09-25 2011-08-23 Ionalytics Corporation Faims apparatus and method for separating ions
US7378651B2 (en) * 2002-09-25 2008-05-27 Thermo Finnigan Llc High field asymmetric waveform ion mobility spectrometer FAIMS
US7358504B2 (en) * 2002-09-25 2008-04-15 Thermo Finnigan Llc FAIMS apparatus and method for separating ions
US7417225B2 (en) * 2002-09-25 2008-08-26 Thermo Finnigan Llc Apparatus and method for adjustment of ion separation resolution in FAIMS
US6822225B2 (en) * 2002-09-25 2004-11-23 Ut-Battelle Llc Pulsed discharge ionization source for miniature ion mobility spectrometers
WO2004040257A2 (en) * 2002-10-12 2004-05-13 Sionex Corporation NOx MONITOR USING DIFFERENTIAL MOBILITY SPECTROMETRY
DE10310394A1 (de) * 2003-03-07 2004-09-23 Wma Airsense Analysentechnik Gmbh Verfahren und Meßsystem zur Erfassung von Gefahrstoffen
US20050085740A1 (en) * 2003-04-01 2005-04-21 Davis Cristina E. Non-invasive breath analysis using field asymmetric ion mobility spectrometry
US7470898B2 (en) 2003-04-01 2008-12-30 The Charles Stark Draper Laboratory, Inc. Monitoring drinking water quality using differential mobility spectrometry
WO2004092705A2 (en) * 2003-04-09 2004-10-28 Brigham Young University Cross-flow ion mobility analyzer
WO2004097396A1 (en) * 2003-04-24 2004-11-11 Sionex Corporation Apparatus and method for controlling ion behavior in ion mobility spectrometry
JP2007524964A (ja) * 2003-06-20 2007-08-30 ブリガム・ヤング・ユニバーシティ イオン移動度分析及びイオントラップ質量分析のための単一装置
US7057166B2 (en) * 2003-06-27 2006-06-06 Ionalytics Corporation Method of separating ions
CA2529505A1 (en) 2003-06-27 2005-01-06 Brigham Young University Virtual ion trap
WO2005028973A2 (en) * 2003-09-17 2005-03-31 Sionex Corporation Solid-state flow generator and related systems, applications, and methods
US7071465B2 (en) 2003-10-14 2006-07-04 Washington State University Research Foundation Ion mobility spectrometry method and apparatus
US7186972B2 (en) * 2003-10-23 2007-03-06 Beckman Coulter, Inc. Time of flight mass analyzer having improved mass resolution and method of operating same
EP1690074A2 (de) * 2003-11-25 2006-08-16 Sionex Corporation Auf mobilität beruhende vorrichtung und verfahren unter verwendung von dispersionseigenschaften, probenfragmentierung und/oder druckkontrolle zur verbesserung der analyse einer probe
EP1697024B1 (de) 2003-12-18 2017-08-30 DH Technologies Development Pte. Ltd. Verfahren und vorrichtung zur verbesserten ionenbasierten probendetektion unter verwendung von selektiver vortrennung und verstärkung
CA2551991A1 (en) 2004-01-13 2005-07-28 Sionex Corporation Methods and apparatus for enhanced sample identification based on combined analytical techniques
EP1562042A3 (de) * 2004-01-22 2007-02-21 Ionalytics Corporation Verfahren und Gerät für FAIMS zur Reihenanalyse mehrerer Proben
US7112788B2 (en) * 2004-01-22 2006-09-26 Ionalytics Corporation Apparatus and method for controllably affecting the temperature of FAIMS components
WO2005074584A2 (en) * 2004-02-02 2005-08-18 Sionex Corporation Compact sample analysis systems and related methods using combined chromatography and mobility spectrometry techniques
JP2007520865A (ja) * 2004-02-03 2007-07-26 オルガニゼイション ユーロピエンヌ プール ラ レシェルシェ ニュークリエル 放射線検出器
CA2499247A1 (en) * 2004-03-03 2005-09-03 Ionalytics Corporation Method and apparatus for selecting inlets of a multiple inlet faims
GB0408751D0 (en) * 2004-04-20 2004-05-26 Micromass Ltd Mass spectrometer
EP1756561A1 (de) * 2004-04-28 2007-02-28 Sionex Corporation System und verfahren zur ionenspeziesanalyse mit verbesserter zustandskontrolle und dateninterpretation unter verwendung differentieller mobilitätsspektrometer
RU2266587C1 (ru) * 2004-07-23 2005-12-20 Государственное научное учреждение "Научно-исследовательский институт ядерной физики при Томском политехническом университете министерства образования Российской Федерации" Способ измерения спектра ионов и времяпролетный спектрометр ионов
AU2005268605A1 (en) * 2004-08-02 2006-02-09 Owlstone Ltd Ion mobility spectrometer
GB0417184D0 (en) * 2004-08-02 2004-09-01 Owlstone Ltd Microchip ion mobility spectrometer
CA2574295C (en) * 2004-08-05 2009-11-24 Ionalytics Corporation Low field mobility separation of ions using segmented cylindrical faims
US7388195B2 (en) * 2004-09-30 2008-06-17 Charles Stark Draper Laboratory, Inc. Apparatus and systems for processing samples for analysis via ion mobility spectrometry
DE112005002204T5 (de) * 2004-10-14 2007-09-27 Electronic Biosciences, LLC, San Diego Integriertes Sensorenfeld zum Erzeugen eines Bio-Fingerprints eines Analyts
EP1810315B1 (de) * 2004-10-28 2014-12-03 Albert Edward Litherland Verfahren und vorrichtung zur trennung von isobarischen interferenzen
GB0424426D0 (en) 2004-11-04 2004-12-08 Micromass Ltd Mass spectrometer
WO2006056049A1 (en) * 2004-11-24 2006-06-01 Ionalytics Corporation Apparatus and method for adjustment of ion separation resolution in faims
WO2006060807A1 (en) * 2004-12-03 2006-06-08 Sionex Corporation Method and apparatus for enhanced ion based sample filtering and detection
WO2006061593A2 (en) * 2004-12-07 2006-06-15 Micromass Uk Limited Mass spectrometer
US8754366B2 (en) * 2005-01-11 2014-06-17 Hamilton Sundstrand Corporation Tandem differential mobility ion mobility spectrometer for chemical vapor detection
US7812309B2 (en) * 2005-02-09 2010-10-12 Thermo Finnigan Llc Apparatus and method for an electro-acoustic ion transmittor
GB0503010D0 (en) * 2005-02-14 2005-03-16 Micromass Ltd Mass spectrometer
US8440968B2 (en) * 2005-02-14 2013-05-14 Micromass Uk Limited Ion-mobility analyser
WO2006086880A1 (en) * 2005-02-17 2006-08-24 Thermo Finnigan Llc Apparatus and method for forming a gas composition gradient between faims electrodes
US7148474B2 (en) * 2005-04-11 2006-12-12 Battelle Memorial Institute Device for two-dimensional gas-phase separation and characterization of ion mixtures
WO2006119167A1 (en) 2005-04-29 2006-11-09 Sionex Corporation Compact gas chromatography and ion mobility based sample analysis systems, methods, and devices
US7351960B2 (en) * 2005-05-16 2008-04-01 Thermo Finnigan Llc Enhanced ion desolvation for an ion mobility spectrometry device
WO2006127974A1 (en) * 2005-05-24 2006-11-30 Sionex Corporation Combined mass and differential mobility spectrometry
WO2007014303A2 (en) 2005-07-26 2007-02-01 Sionex Corporation Ultra compact ion mobility based analyzer system and method
GB0808344D0 (en) * 2008-05-08 2008-06-18 Owlstone Ltd Sensor
US7358487B2 (en) * 2005-09-19 2008-04-15 Owlstone Nanotech, Inc. Ion gate
EP1927125A2 (de) * 2005-09-19 2008-06-04 Owlstone Ltd Ionenpumpe
US7449683B2 (en) * 2005-09-28 2008-11-11 Battelle Memorial Institute Method and apparatus for high-order differential mobility separations
FI119660B (fi) * 2005-11-30 2009-01-30 Environics Oy Kaasun ioniliikkuvuuden mittausmenetelmä ja -laite
CN101568765B (zh) * 2005-12-19 2012-01-25 皇家飞利浦电子股份有限公司 用于发生蒸汽的装置和方法
CA2632251C (en) * 2005-12-22 2011-06-21 Thermo Finnigan Llc Apparatus and method for pumping in an ion optical device
US20070272852A1 (en) * 2006-01-26 2007-11-29 Sionex Corporation Differential mobility spectrometer analyzer and pre-filter apparatus, methods, and systems
WO2007123464A1 (en) * 2006-04-20 2007-11-01 Axel Mie Method for separation of molecules
US7397027B2 (en) * 2006-05-30 2008-07-08 Agilent Technologies, Inc. Multi-channel high-field asymmetric waveform ion mobility spectrometry
US7468511B2 (en) 2006-06-13 2008-12-23 Thermo Finnigan, Llc FAIMS electrodes with lateral ion focusing
US7812305B2 (en) * 2006-06-29 2010-10-12 Sionex Corporation Tandem differential mobility spectrometers and mass spectrometer for enhanced analysis
GB0613900D0 (en) * 2006-07-13 2006-08-23 Micromass Ltd Mass spectrometer
GB0622780D0 (en) 2006-11-15 2006-12-27 Micromass Ltd Mass spectrometer
US7550717B1 (en) 2006-11-30 2009-06-23 Thermo Finnigan Llc Quadrupole FAIMS apparatus
US8217344B2 (en) * 2007-02-01 2012-07-10 Dh Technologies Development Pte. Ltd. Differential mobility spectrometer pre-filter assembly for a mass spectrometer
US7723679B2 (en) * 2007-02-23 2010-05-25 Brigham Young University Coaxial hybrid radio frequency ion trap mass analyzer
EP2126961B1 (de) * 2007-02-24 2014-06-18 Sociedad Europea De Analisis Diferencial De Movilidad S.L. Verfahren zur genauen unterscheidung von gasphasenionen mit mehreren filtereinrichtungen in tandemschaltung
DE102007017055B4 (de) * 2007-04-11 2011-06-22 Bruker Daltonik GmbH, 28359 Messung der Mobilität massenselektierter Ionen
JP4862738B2 (ja) * 2007-05-08 2012-01-25 株式会社日立製作所 イオン移動度分析装置およびイオン移動度分離／質量分析複合装置
US7863562B2 (en) * 2007-06-22 2011-01-04 Shimadzu Corporation Method and apparatus for digital differential ion mobility separation
JP4905270B2 (ja) * 2007-06-29 2012-03-28 株式会社日立製作所 イオントラップ、質量分析計、イオンモビリティ分析計
US8173959B1 (en) * 2007-07-21 2012-05-08 Implant Sciences Corporation Real-time trace detection by high field and low field ion mobility and mass spectrometry
US7638765B1 (en) 2007-07-27 2009-12-29 Thermo Finnigan Llc FAIMS cell with separate desolvation and carrier gas inlets
US8334506B2 (en) 2007-12-10 2012-12-18 1St Detect Corporation End cap voltage control of ion traps
US7858934B2 (en) * 2007-12-20 2010-12-28 Thermo Finnigan Llc Quadrupole FAIMS apparatus
US8067731B2 (en) * 2008-03-08 2011-11-29 Scott Technologies, Inc. Chemical detection method and system
EP2112683A1 (de) 2008-04-22 2009-10-28 IEE INTERNATIONAL ELECTRONICS & ENGINEERING S.A. Differentialmobilitätsspektrometer und Betriebsverfahren dafür
US7973277B2 (en) 2008-05-27 2011-07-05 1St Detect Corporation Driving a mass spectrometer ion trap or mass filter
US20100282966A1 (en) * 2008-05-30 2010-11-11 DH Technologies Development Pte Ltd. Method and system for vacuum driven mass spectrometer interface with adjustable resolution and selectivity
EP2281297B1 (de) * 2008-05-30 2019-01-16 DH Technologies Development Pte. Ltd. Verfahren und system für vakuumgesteuerte dms-spektrometer-/massenspektrometerschnittstelle mit einstellbarer auflösung und selektivität
DE102008063233B4 (de) * 2008-12-23 2012-02-16 Bruker Daltonik Gmbh Hohe Massenauflösung mit ICR-Messzellen
GB0907619D0 (en) * 2009-05-01 2009-06-10 Shimadzu Res Lab Europe Ltd Ion analysis apparatus and method of use
JP5985989B2 (ja) * 2010-01-28 2016-09-06 エムディーエス アナリティカル テクノロジーズ， ア ビジネス ユニット オブ エムディーエス インコーポレイテッド 低圧微分移動度分光計を備えた質量分析システム
GB201002445D0 (en) 2010-02-12 2010-03-31 Micromass Ltd Improved differentiation and determination of ionic conformations by combining ion mobility and hydrogen deuterium exchange reactions
US8158932B2 (en) 2010-04-16 2012-04-17 Thermo Finnigan Llc FAIMS having a displaceable electrode for on/off operation
RU2434226C1 (ru) * 2010-07-19 2011-11-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Национальный исследовательский ядерный университет "МИФИ" (НИЯУ МИФИ) Устройство для получения и анализа ионов аналита
RU2434225C1 (ru) * 2010-07-19 2011-11-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Национальный исследовательский ядерный университет "МИФИ" (НИЯУ МИФИ) Способ получения и анализа ионов аналита
EP2603307B1 (de) * 2010-08-10 2018-10-10 Shimadzu Corporation Vorhanggasfilter für hochfluss-ionenquellen
GB201021360D0 (en) * 2010-12-16 2011-01-26 Thermo Fisher Scient Bremen Gmbh Apparatus and methods for ion mobility spectrometry
DE102011008713B4 (de) * 2011-01-17 2012-08-02 Bruker Daltonik Gmbh Kingdon-Ionenfallen mit Cassini-Potentialen höherer Ordnung
US9395333B2 (en) 2011-06-22 2016-07-19 Implant Sciences Corporation Ion mobility spectrometer device with embedded faims
US9068943B2 (en) 2011-04-27 2015-06-30 Implant Sciences Corporation Chemical analysis using hyphenated low and high field ion mobility
WO2012167254A1 (en) * 2011-06-03 2012-12-06 Dh Technologies Development Pte. Ltd. Method and system for reducing interferences in the spectrometric analysis of steroids
US8502138B2 (en) * 2011-07-29 2013-08-06 Sharp Kabushiki Kaisha Integrated ion mobility spectrometer
CN102354650A (zh) * 2011-09-20 2012-02-15 中国科学院化学研究所 一种电喷雾离子源装置
RU2476870C1 (ru) * 2011-11-02 2013-02-27 Федеральное государственное унитарное предприятие "Научно-исследовательский технологический институт имени А.П. Александрова" Способ разделения и регистрации ионов в газе (варианты)
WO2013080044A2 (en) * 2011-11-17 2013-06-06 Owlstone Limited Sensor apparatus and method for use with gas ionization systems
WO2013152344A1 (en) 2012-04-06 2013-10-10 Implant Sciences Corporation Selective ionization using high frequency filtering of reactive ions
US9134273B2 (en) 2012-05-18 2015-09-15 Dh Technologies Development Pte. Ltd. Methods for selective detection of biologically relevant acids
US9188565B2 (en) * 2012-05-31 2015-11-17 The University Of North Carolina At Chapel Hill High field asymmetric ion mobility spectrometry (FAIMS) methods and devices with voltage-gas composition linked scans
CN102901753A (zh) * 2012-09-24 2013-01-30 杭州泰林生物技术设备有限公司 液体氧化检测电极及其装置
GB201314977D0 (en) 2013-08-21 2013-10-02 Thermo Fisher Scient Bremen Mass spectrometer
CN104569233B (zh) * 2013-10-28 2018-04-24 同方威视技术股份有限公司 离子迁移谱仪系统
WO2015191569A1 (en) * 2014-06-13 2015-12-17 Perkinelmer Health Sciences, Inc. Rf ion guide with axial fields
JP6306797B2 (ja) * 2014-07-30 2018-04-04 ヒューレット−パッカード デベロップメント カンパニー エル．ピー．Ｈｅｗｌｅｔｔ‐Ｐａｃｋａｒｄ Ｄｅｖｅｌｏｐｍｅｎｔ Ｃｏｍｐａｎｙ， Ｌ．Ｐ． 加熱機能を有するイオン書き込みユニット
GB2569059B (en) * 2014-10-14 2019-09-25 Smiths Detection Watford Ltd Method and apparatus
GB2531292B (en) * 2014-10-14 2019-06-12 Smiths Detection Watford Ltd Method and apparatus
US9766218B2 (en) * 2014-10-31 2017-09-19 Morpho Detection, Llc Gas curtain at inlet for trace detectors
JP6288367B2 (ja) 2015-03-09 2018-03-07 株式会社島津製作所 平行平板型不均一電場イオン移動度分光装置
WO2018084868A1 (en) 2016-11-07 2018-05-11 Wood Mark W Scroll compressor with circular surface terminations
US10030658B2 (en) 2016-04-27 2018-07-24 Mark W. Wood Concentric vane compressor
US11480178B2 (en) 2016-04-27 2022-10-25 Mark W. Wood Multistage compressor system with intercooler
US11686309B2 (en) 2016-11-07 2023-06-27 Mark W. Wood Scroll compressor with circular surface terminations
US10049868B2 (en) 2016-12-06 2018-08-14 Rapiscan Systems, Inc. Apparatus for detecting constituents in a sample and method of using the same
GB202004961D0 (en) 2020-04-03 2020-05-20 Micromass Ltd De-clustering guide
US11092569B1 (en) 2020-07-05 2021-08-17 Cannabix Technologies Inc. Apparatus and methods for detection of molecules

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2003A (en) * 1841-03-12 Improvement in horizontal windivhlls
US2002A (en) * 1841-03-12 Tor and planter for plowing
US2001A (en) * 1841-03-12 Sawmill
US3668383A (en) * 1969-01-09 1972-06-06 Franklin Gno Corp Apparatus and methods for separating, detecting, and measuring trace gases
JPS50119696A (de) * 1974-03-04 1975-09-19
US4234791A (en) * 1978-11-13 1980-11-18 Research Corporation Tandem quadrupole mass spectrometer for selected ion fragmentation studies and low energy collision induced dissociator therefor
US4311669A (en) * 1980-08-21 1982-01-19 The Bendix Corporation Membrane interface for ion mobility detector cells
US4501965A (en) * 1983-01-14 1985-02-26 Mds Health Group Limited Method and apparatus for sampling a plasma into a vacuum chamber
US5106468A (en) * 1985-12-30 1992-04-21 Exxon Research And Engineering Company Electrophoretic separation
US5026987A (en) * 1988-06-02 1991-06-25 Purdue Research Foundation Mass spectrometer with in-line collision surface means
US5073713A (en) * 1990-05-29 1991-12-17 Battelle Memorial Institute Detection method for dissociation of multiple-charged ions
US5283199A (en) * 1990-06-01 1994-02-01 Environmental Technologies Group, Inc. Chlorine dioxide monitor based on ion mobility spectrometry with selective dopant chemistry
US5248875A (en) * 1992-04-24 1993-09-28 Mds Health Group Limited Method for increased resolution in tandem mass spectrometry
US5420424A (en) * 1994-04-29 1995-05-30 Mine Safety Appliances Company Ion mobility spectrometer
US5523566A (en) * 1994-07-20 1996-06-04 Fuerstenau; Stephen D. Method for detection and analysis of inorganic ions in aqueous solutions by electrospray mass spectrometry
US5520424A (en) 1995-01-30 1996-05-28 U.S. Controls Copr. Tamper-proof door switch and latch device
CA2229070C (en) * 1995-08-11 2007-01-30 Mds Health Group Limited Spectrometer with axial field
US5811800A (en) * 1995-09-14 1998-09-22 Bruker-Franzen Analytik Gmbh Temporary storage of ions for mass spectrometric analyses
RU2105298C1 (ru) 1995-10-03 1998-02-20 Владилен Федорович Минин Способ анализа микропримесей веществ в воздухе "ионозолер-2"
US5801379A (en) * 1996-03-01 1998-09-01 Mine Safety Appliances Company High voltage waveform generator
US5736739A (en) * 1996-04-04 1998-04-07 Mine Safety Appliances Company Recirculating filtration system for use with a transportable ion mobility spectrometer in gas chromatography applications
US5763876A (en) * 1996-04-04 1998-06-09 Mine Safety Appliances Company Inlet heating device for ion mobility spectrometer
US5723861A (en) * 1996-04-04 1998-03-03 Mine Safety Appliances Company Recirculating filtration system for use with a transportable ion mobility spectrometer
US5869831A (en) * 1996-06-27 1999-02-09 Yale University Method and apparatus for separation of ions in a gas for mass spectrometry
RU2105296C1 (ru) 1996-07-24 1998-02-20 Всероссийский научно-исследовательский институт минерального сырья им.Н.М.Федоровского Способ определения нитрит-иона в растворе
US6960761B2 (en) 1997-06-02 2005-11-01 Advanced Research & Technology Institute Instrument for separating ions in time as functions of preselected ion mobility and ion mass
US5905258A (en) * 1997-06-02 1999-05-18 Advanced Research & Techology Institute Hybrid ion mobility and mass spectrometer
US6498342B1 (en) * 1997-06-02 2002-12-24 Advanced Research & Technology Institute Ion separation instrument
US6323482B1 (en) * 1997-06-02 2001-11-27 Advanced Research And Technology Institute, Inc. Ion mobility and mass spectrometer
US5955886A (en) * 1997-07-10 1999-09-21 Pcp, Inc. Microliter-sized ionization device and method
CA2245022C (en) * 1997-08-22 2007-06-12 Mds Inc. Ion source
US6040573A (en) * 1997-09-25 2000-03-21 Indiana University Advanced Research & Technology Institute Inc. Electric field generation for charged particle analyzers
US5789745A (en) * 1997-10-28 1998-08-04 Sandia Corporation Ion mobility spectrometer using frequency-domain separation
US6041734A (en) * 1997-12-01 2000-03-28 Applied Materials, Inc. Use of an asymmetric waveform to control ion bombardment during substrate processing
EP1051733B1 (de) * 1997-12-04 2004-08-18 University Of Manitoba Vorrichtung und verfahren zur stoss-induzierten dissoziation von ionen in einem quadrupol-ionenleiter
AU1329899A (en) 1997-12-05 1999-06-28 University Of British Columbia, The Method of analyzing ions in an apparatus including a time of flight mass spectrometer and a linear ion trap
US6015972A (en) * 1998-01-12 2000-01-18 Mds Inc. Boundary activated dissociation in rod-type mass spectrometer
AU2463299A (en) * 1998-01-23 1999-08-09 Analytica Of Branford, Inc. Mass spectrometry from surfaces
US6124592A (en) * 1998-03-18 2000-09-26 Technispan Llc Ion mobility storage trap and method
EP1102984A1 (de) * 1998-08-05 2001-05-30 National Research Council of Canada Verfahren zur isomertrennung und trennung verschiedener ionenkonformationen in der gasphase
US6504149B2 (en) * 1998-08-05 2003-01-07 National Research Council Canada Apparatus and method for desolvating and focussing ions for introduction into a mass spectrometer
US6621077B1 (en) * 1998-08-05 2003-09-16 National Research Council Canada Apparatus and method for atmospheric pressure-3-dimensional ion trapping
CA2255122C (en) * 1998-12-04 2007-10-09 Mds Inc. Improvements in ms/ms methods for a quadrupole/time of flight tandem mass spectrometer
US6410914B1 (en) * 1999-03-05 2002-06-25 Bruker Daltonics Inc. Ionization chamber for atmospheric pressure ionization mass spectrometry
EP1047107B1 (de) * 1999-04-06 2006-10-04 Micromass UK Limited Verfahren zur Identifizierung von Peptiden und Proteinen mittels Massenspektromterie
AU3952200A (en) 1999-04-16 2000-11-02 Mds Inc. Mass spectrometer, including coupling of an atmospheric pressure ion source to alow pressure mass analyzer
JP2003525515A (ja) * 1999-06-11 2003-08-26 パーセプティブ バイオシステムズ，インコーポレイテッド 衝突室中での減衰を伴うタンデム飛行時間型質量分析計およびその使用のための方法
US6512224B1 (en) * 1999-07-21 2003-01-28 The Charles Stark Draper Laboratory, Inc. Longitudinal field driven field asymmetric ion mobility filter and detection system
US6495823B1 (en) * 1999-07-21 2002-12-17 The Charles Stark Draper Laboratory, Inc. Micromachined field asymmetric ion mobility filter and detection system
US6815668B2 (en) * 1999-07-21 2004-11-09 The Charles Stark Draper Laboratory, Inc. Method and apparatus for chromatography-high field asymmetric waveform ion mobility spectrometry
US6525314B1 (en) * 1999-09-15 2003-02-25 Waters Investments Limited Compact high-performance mass spectrometer
WO2001022049A2 (en) 1999-09-24 2001-03-29 Haley Lawrence V A novel ion-mobility based device using an oscillatory high-field ion separator with a multi-channel array charge collector
AU2001239076A1 (en) * 2000-03-14 2001-09-24 National Research Council Canada Tandem high field asymmetric waveform ion mobility spectrometry (faims)/ion mobility spectrometry
AU3907301A (en) * 2000-03-14 2001-09-24 Ca Nat Research Council Faims apparatus and method with laser-based ionization source
CA2402793C (en) 2000-03-14 2009-06-16 National Research Council Of Canada Improved parallel plate geometry faims apparatus and method
JP3976470B2 (ja) * 2000-04-13 2007-09-19 本州化学工業株式会社 ブチルフェノール類の脱ブチル化方法
US6417511B1 (en) * 2000-07-17 2002-07-09 Agilent Technologies, Inc. Ring pole ion guide apparatus, systems and method
US6598553B1 (en) * 2002-02-13 2003-07-29 Mark X Steering Systems, Llc Power assist marine steering system

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